Hungarian Wound Care Society

Skeletal Muscle Mass Index and Risk of Lower Extremity Ulcers: Analysis of NHANES Data with External Hospital Validation - PubMed
Abstract by Honglei Wang and Yefeng Shen (Beijing, China - Int J Low Extrem Wounds).

Immune cells in diabetic wound repair: the key to better wound management - PubMed
Abstract by Yi Ru, Yunxi Cai, Guangyuan Cheng, Xiaoxuan Ma et al. (Shanghai, China - Front Med.).

Comparative Analysis of Physicochemical Properties and Biocompatibility of Biomass-Derived and Fossil-Derived Polyvinyl Alcohol Hydrogels: Material Screening for Wound Dressing Applications - Mdpi.com
Article by Shanshan Wang, Yun Liu, Han Li, An Xu and Wenqing Liu (Hefei, China - Gels). The authors findings strongly validated the benefits and applicability of biomass-derived polyvinyl alcohol in wound dressing, especially for addressing complex wounds necessitating both physical defense and drug-based intervention.

The mechanism by which negative pressure wound therapy promotes wound healing - PubMed
Abstract by Ying Zeng, Jianjian Tu and Jichao Qin (China - J Tissue Viability).

Evaluation of heparin gel's effects on stage II pressure ulcers: a randomized controlled trial - PubMed
Abstract by Raheleh Khani, Leila Behbood, Masoud Fallahi, Shahab Rezaeian and Foroud Shahbazi (Kermanshah, Iran - Eur J Med Res.).

Pressure Injuries in Critically Ill Patients With Ischaemic Stroke: Prevalence, Risk Factors and Clinical Outcomes - PubMed
Abstract by Yinhua Liu, Jing Luo, Lijun Huang, Huanyi Liang et al. (China - Nurs Crit Care).

Nanotechnology in Wound Healing: A New Frontier in Regenerative Medicine - Researchgate.net
Article by Alibala Aliyev, Aygun Israyilova, Ulviyya Hasanova, Zarema Gakhramanova and Aida Ahmadova (Baku, Azerbaijan - Micro). Nanocomposite hydrogels are particularly advantageous as biointeractive dressings due to their ability to maintain wound moisture while facilitating regulated drug delivery. Recent advancements indicate their potential to aid in tissue regeneration, enhance therapy precision, and address issues related to safety and translation. Nanotechnology-based approaches, especially smart hydrogels, give significant promise to transform the future of wound care due to their flexibility, adaptability, and efficiency.

Experts Highlight Emerging Biophysical Approaches to Advanced Wound Care - Generalsurgerynews.com
Article by Jenna Bassett. Wounds that heal improperly, incompletely or too slowly may lead to chronic wounds and morbidity that can impose a significant burden on the patient and provider. It comes as no surprise, then, that clinicians and researchers have developed advanced wound care technologies to support safe and optimized healing.

A Scoping Review of Clinical Trials on the Efficacy of Curcumin and Its Formulations for Wound Healing - Nih.gov
Article by Mohammad Mahdi Parvizi, Ali Arefkia, Yasamin Dehghan, Mohammad Ali Salimi and Negin Fazelzadeh Haghighi (Shiraz, Iran - J Cosmet Dermatol.). According to the findings of the current study, curcumin is a safe and effective adjuvant for improving wound healing. However, the significant heterogeneity observed among clinical trials limits the ability to develop consistent treatment guidelines.

Patient-Reported Outcomes Favor Below-Knee Over Above-Knee Amputation in Patients With Nontraumatic Lower Extremity Wounds - Hmpgloballearningnetwork.com
Article by Ryan P. Lin, Danny S. Chamaa, Sami Ferdousian, Rachel N. Rohrich et al. (USA - Wounds). The study results indicate that patients who have undergone above-knee amputation have higher pain intensity, more psychological distress, and lower function compared with patients who have undergone below-knee amputation (BKA). These findings underly the importance of performing a BKA when possible.

Revolutionizing Wound Care: Innovative Wound Care Technology Transforming Patient Outcomes - Healogics.com
Modern wound care has changed dramatically over the past several decades. What once relied on simple bandages, ointments, and time has evolved into a sophisticated field supported by biotechnology, materials science, and advanced digital tools. Today’s wound care technology does far more than cover a wound; it interacts with the healing process, addresses barriers to recovery, and supports the body’s ability to repair itself.

Hydrogel Microneedle Array-Based Transdermal Dressing System for Multiplexed Assessment and Intelligent Therapy of Chronic Wounds - Wiley.com
Article by Md Sharifuzzaman, Gauri Hasabnis, Sheikh Ahmed Abu Saleh, Leonard Siebert et al. (Kiel, Germany - Small - Nanoscience & Nanotechnology Journal). This work validates a robust platform that directly links deep-tissue biomarkers to wound state, paving the way for personalized, proactive chronic wound management.

Evaluate Wound Healing Time and Infection Control Measures - Saspublishers.com
Article by Tanusree Burmon, Mahbuba Akhter, A. K. M. Lutful Haque, Mohiuddin Biswas and Saba Al Galib (Bangladesh - Sch J App Med Sci). L-lysine shortens the time it takes for granulation tissue to form and speeds up wound healing. However, additional clinical trials are needed to determine the significance of L-lysin as a possible drug for surgical site infection treatment.

Comparison of 'Lite' reduced compression two-layer bandages for treatment of leg ulcers: Results of the pragmatic, single-centre randomized controlled PEACH trial - PubMed
Abstract by Jane Todhunter, Helen Greenhow and Leon Jonker (Carlisle, UK - J Vasc Nurs.).

Wounds and the Microbiota: The Healing Interplay Between Host and Microbial Communities - Mdpi.com
Article by Raghad Al-Taweel, Ayat S Hammad, Ali Tajammul, Sergio Crovella and Maha Al-Asmakh (Doha, Qatar - IJMS). This review integrates current molecular insights and bibliometric trends to highlight advances and remaining challenges in understanding the wound–microbiome axis. A deeper grasp of these interactions can inform next-generation, microbiome-targeted therapies for chronic wounds.

Deep Eutectic Solvents in Chronic Wound Management: Current Developments and Future Prospects - Dovepress.com
Article by Rakesh Bastola and Raj Kumar Thapa (Pokhara, Nepal - International Journal of Nanomedicine). Deep Eutectic Solvents represent novel and versatile therapeutic platforms that have the potential to transform the treatment landscape of chronic wound healing.

Nanotechnology in Wound Healing: A New Frontier in Regenerative Medicine - Mdpi.com
Article by Alibala Aliyev, Aygun Israyilova, Ulviyya Hasanova, Zarema Gakhramanova and Aida Ahmadova (Baku, Azerbaijan - Micro). Nanocomposite hydrogels are particularly advantageous as biointeractive dressings due to their ability to maintain wound moisture while facilitating regulated drug delivery. Recent advancements indicate their potential to aid in tissue regeneration, enhance therapy precision, and address issues related to safety and translation.

A Multi‐Centre, Randomised, Controlled Clinical Trial Assessing Cryopreserved Ultra‐Thick Human Amniotic Membrane in the Treatment of Complex Diabetic Foot Ulcers - Nih.gov
Article by Joseph Caporusso, Travis Motley, John C Lantis II, Stephen Heisler et al. (USA - Wound Repair Regen.). Herein, a randomised controlled trial was conducted to assess the safety and efficacy of umbilical cord versus standard of care (SOC) for DFUs with exposed bone, tendon, muscle and/or joint capsule and controlled osteomyelitis. While there were no significant differences in healing rates or adverse events between the two treatment arms at any time point, this study demonstrates that adjunctive cUC is safe and helps achieve a high healing rate at 50 weeks with less than four applications for complex DFUs that are often excluded in clinical trials.

Editorial: Prevention and Treatment of Skin Diseases - Frontiersin.org
Article by Rosa di Liddo, Francesca Caroppo, Masaoki Kawasumi and Barbara Zavan (Italy, USA - Front. Pharmacol.). Skin wounds represent a significant global health issue, as they can be a sign of an underlying disease and require specialized care to heal properly. When a reparative process rather than regeneration occurs, nonfunctional fibrotic tissue masses, namely scars, develop. Currently, empirical treatments often rely on a one-size-fits-all approach, failing to consider individual patient characteristics. Thus, they have several limitations, such as 1) a lack of standardization and evidence; 2) ineffectiveness; and 3) practical restrictions.

Tap Water vs. Sterile Saline for Irrigation of Traumatic Soft-Tissue Wounds in the ED - Cureus.com
Article by Henry Mills, Nikhil Pandit, Lucky Jeyaseelan and Amit Patel (UK). The authors' findings, combined with the considerable reductions in cost and environmental impact, along with the greater practicality of tap water, suggest it is a safe and effective alternative when potable water is available.

An Ultrafast Self-Gelling Versatile Hydrogel for Rapid Infected Burn Wound Repair in Military Medicine - Wiley.com
Article by Liping Zhang, Zhangrui Wu, Xiansheng Zhao, Geng Wang et al. (Hangzhou, China - Advanced Functional Materials). The authors' results indicate that PG@PAC is a potential all-in-one ready-to-use dressing for infected burn wound under resource-limited environments and provide a promising envision of battlefield wound management.

Be there or be square: Should we adopt non-rectangular dressing shapes in single-use negative pressure wound therapy? - PubMed
Abstract by Ofek Barzilay and Amit Gefen (Israel, Belgium - J Tissue Viability).

Scientists say this viral rosemary skincare trend actually works - Sciencedaily.com
Researchers have found scientific support for the viral claim that rosemary can improve wound healing. Carnosic acid, a natural antioxidant in rosemary, promoted scar-free healing in mice by activating a nerve sensor tied to regenerative repair. Rosemary proved more potent and gentler than other herbs or compounds that target the same pathway.

Combining Light And Platelet Rich Plasma (PRP): Huge Wound Healing Boost? - Lighttherapyinsiders.com
PRP is derived from your own blood, by taking it out of your body. What happens next is that the platelets and growth factors are concentrated outside the body. The PRP is then reinjected into the injured area to stimulate healing or just to plain improve cellular functioning. So you can use PRP to heal but also for anti-aging purposes.

In vitro assessment of shear force buffering in sacral dressings to alleviate pressure injuries in bed-based patients - PubMed
Abstract by Rory Turnbull, Dominic Jones, Ali Alazmani and Pete Culmer (Leeds, UK - J Wound Care).

A decade of global research activity in pressure ulcer science: a survey of publication patterns (2015-2024) - PubMed
Abstract by Yimei Tan, Huolin Zheng, Ling Li and Yanping Kuang (Ganzhou, China - J Wound Care).

Therapeutic Potential of Chitosan-Based and Related Nanocomposite Systems in Wound Management: A Review - Mdpi.com
Article by Beata Bielska and Katarzyna Miłowska (Lodz, Poland - IJMS). This review methodically synthesises the extant experimental evidence demonstrating that these multifunctional systems exhibit regenerative, antioxidant, and antimicrobial properties that may support selected biological processes relevant to wound repair. The promotion of angiogenesis, fibroblast growth, and epithelial regeneration is accompanied by a reduction in infection-related complications.

Retrospective case series: Skin protection and wound management - Woundsinternational.com
Article by Junya Kawada, Koichi Kono, Jaraspas Wongviseskarn, Liqiong Li et al. (Wounds). This retrospective case series highlights the successful use of Aquacel® Foam Pro dressings and other products for skin protection and wound management by healthcare practitioners across the Asia-Pacific region. The cases demonstrate the versatility of these dressings in protecting at-risk anatomical areas and supporting the management of various wound types, from preserving skin integrity during prolonged prone positioning to treating established pressure injuries and skin tears.

Biofilm in Diabetic Foot Ulcers: A Systematic Narrative Review - Wiley.com
Article by George Theodorakopoulos and David G. Armstrong (Greece, UK, USA - International Wound Journal). Current data justify maintaining guideline-based care while prioritising trials that integrate validated biofilm endpoints, standardised microbiological methods, and antifungal components. Distinguishing established from experimental approaches is essential to advancing safe, evidence-based biofilm management in DFUs.

Effect of Dry Carbonic Acid Baths on Blood Rheological Parameters in Patients with Venous Leg Ulcers - PubMed
Article by Patrycja Dolibog, Paweł Tomasz Dolibog, Mikołaj Łanocha, Marcelina Paruzel et al. (Poland - JCM). CO2 dry baths support the treatment of venous ulcers by improving microcirculation and reducing pain. Their impact on blood rheology may have clinical significance, especially as an adjunct to therapy in chronic venous insufficiency.

Platelet-Rich Plasma (PRP) and Recombinant Growth Factor Therapies in Cutaneous Wound Healing: Mechanisms, Clinical Applications, and Future Directions - PubMed
Article by Abu-Bakr Ahmed, Spencer Thatcher, Joshua Khorsandi, Zahra Ahmed et al. (USA - JCM). PRP offers broad, autologous biologic activation, while recombinant growth factors deliver high-potency, targeted precision. Together, they represent complementary regenerative strategies that can shorten healing times and improve outcomes in chronic wounds.

Extracorporeal Shockwave Therapy for Diabetes Related Foot Ulcers: A Pilot Three-Arm Double-Blinded Randomised Controlled Trial - PubMed
Article by L. Hitchman, R. Lathan, B. Ravindhran, M. Sidapra et al. (UK - Int Wound J.).

The Use of Plant-Derived Extracellular Vesicles in Regenerative Medicine Applied to Cutaneous Wound Healing - Mdpi.com
Article by Victoria Pulido-Escribano, Marta Camacho-Cardenosa, Gabriel Dorado, José Manuel Quesada-Gómez et al. (Córdoba, Spain - Pharmaceutics). This review aims to describe the current state of knowledge on the potential therapeutic use of plant-derived extracellular vesicles in wound healing. It also describes the methods of obtaining and applying them, as well as regenerative processes in which they may intervene.

Wearable Electrochemical Biosensors for Monitoring and Management of Chronic Wounds - Mdpi.com
Article by Lingxia Zuo, Yinbing Liu, Jianrong Zhang, Linlin Wang and Jun-Jie Zhu (China - Biosensors). The review explores future trends, such as biodegradable sensors, multi-parameter fusion algorithms, and remote intelligent management systems, with the aim of establishing a foundational framework and providing technical guidance for developing next-generation intelligent wound care solutions.

The Efficiency of Platelet-Rich Plasma (PRP) in Treating Post-Burn and Surgical Scars: A Meta-Analysis Study - Mdpi.com
Article by Ziyad Alharbi and Tala Zafar (Jeddah, Saudi Arabia - JCM). This meta-analysis indicates that PRP may provide significant subjective enhancements in scar quality, particularly from the patient’s viewpoint. The results show the need for standardized PRP protocols, prolonged follow-up periods, and the integration of both patient-centered and objective outcome measures. PRP has significant potential in early postoperative wound healing; nevertheless, additional high-quality, long-term studies are required to clarify its role in mature or fibrotic scars.

Artificial Intelligence in the Management and Treatment of Pediatric Burns: A Narrative Review of Current Applications and Future Directions - Cureus.com
Article by Roban Shabbir, Emilia Preda, Harleen K. Multani, Tioluwa Akinjaiyeju et al. (USA). AI has the potential to complement clinician judgment in pediatric burn care, most immediately for early image-based assessment and remote follow-up. Broader adoption will require pediatric-focused datasets, rigorous external validation, transparent governance for privacy and bias, and clear human-in-the-loop oversight.

How the curvature of a wound leads to healing - Nature.com
Article by Biplab Das. Although characterized in epithelial wound healing, such curvature-dependent ER reorganization may also operate in other systems whether in collective cell migration or in systems such as neuronal growth cones.