Hungarian Wound Care Society

Comparison of wound healing after bypass surgery versus endovascular therapy for dialysis-dependent or independent patients with chronic limb-threatening ischemia and inframalleolar disease: A retrospective cohort study - Sciencedirect.com
Abstract by Shun Kurose, Koichi Morisaki, Daisuke Matsuda, Atsushi Guntani et al. (Japan - Annals of Vascular Surgery).

Wound state monitoring by multiplexed, electrochemical, real-time, localized, inflammation-tracking nitric oxide sensor (MERLIN) - Science.org
Article by Liyang Wang, Yinqiao Wang, Mabel Bartlett, Daniel San Roman et al. (Pittsburgh, USA - Science Advances). MERLIN allows spatial mapping of the NO gradient across the wound bed, which can be used to provide diagnostic information to assist wound care.

Real-time sensors to inform better wound care - Cmu.edu
Wound assessment can be challenging due to its subjective nature, but a new sensor array quantifies biomarkers and has potential to offer real time measurements that could improve the healing process.

Applying Antimicrobial Strategies in Wound Care Practice: A Review of the Evidence - Wiley.com
Article by Joanna Blackburn, Karen Ousey, Mark Rippon, Alan Rogers, Irena Pastar and Hadar Lev-Tov (UK, Australia, USA - International Wound Journal). This review aimed to explore the current barriers to antimicrobial stewardship in wound care clinical practice and discuss the strategies that can be applied to successfully maximise infection prevention.

Polymeric Nanomedicines in Diabetic Wound Healing: Applications and Future Perspectives - Tandfonline.com
Article by Zeyao Chen, Kakei Chan, Xin Li, Li Gong et al. (China, Australia - International Journal of Nanomedicine). Polymeric nanomedicines (PNs) represent an innovative and promising approach to diabetic wound management, outperforming conventional therapies in stability, targeted delivery, and multifunctionality. In the future, investigations should concentrate on refining PNs formulations and administration strategies so as to enhance biocompatibility, and conducting well-designed clinical trials to validate their therapeutic efficacy.

Implementation of a validated non-healing wounds pathway in practice: learning from UK healthcare settings - Wounds-uk.com
Article by Jacqui Fletcher, Rosie Callaghan, Claire Checkley, Jacqueline Dark et al. (Wounds). This document does not provide conceptual background on sNPWT, except a brief introduction. For that purpose, references to relevant literature are provided throughout. It is not possible to overstate the importance of early identification and intervention for achieving optimal outcomes for people with non-healing wounds.

Herbal dual-network hydrogel: A programmed release for enhanced scarless wound healing - Sciencedirect.com
Abstract by Yiming Lin, Qiang Yu, Ruonan Dong, Chenying Shu et al. (China - Chemical Engineering Journal).

Discovery offers new insights into skin healing in salmon - Stir.ac.uk
University of Stirling scientists have discovered cells in the skin of Atlantic salmon that offer new insights into how wounds heal, tissues regenerate, and cellular transitions support long-term skin health.

Innovative approaches to managing diabetic wounds with smart bioactive dressings - News-medical.net
A recent study published in Engineering delves into the advancements in wound management, specifically focusing on microenvironment-sensitive bioactive dressings for diabetic wounds. Diabetic wounds (DWs) are a major complication of diabetes mellitus. With the global diabetic population on the rise, the number of people at risk of developing DWs is also increasing. The lifetime risk of developing DWs for diabetics ranges from 19% to 34%, and the recurrence rate is high, posing a significant challenge to patient health.

Uncovering the Advantages of Foam Dressings with Active Ingredients - Sciencedirect.com
Article by Daniela Chrysostomou, Georgios E. Papanikolaou, Lorraine Boshoff, Thandazi Mbele et al. (Czech Republic, The Netherlands - Pharmaceuticals). Ideally, a foam dressing should have adequate absorption and retention capacities, effectively resolve and prevent infections, protect against external trauma, ensure optimal patient comfort without damaging newly formed granulation tissue, accelerate wound healing processes, and reduce wound care time (e.g., remaining in place for 7 days). Together, these factors make honey- or silver-loaded foam dressings more cost-effective than plain dressings due to their antimicrobial activities and ability to nourish tissues.

Systematic review and meta-analysis of the use of micrografting technology in humans - Sagepub.com
Article by Rawan Almujaydil, Yumeng Yan, Sandra Kuswandani, Faisal Alotaibi et al. (UK, Saudi Arabia - J Int Med Res.). Micrografting technology may lead to shorter healing time and improved patient morbidity.

The Impact of Prophylactic Negative Wound Pressure Treatment (NWPT) on Surgical Site Occurrences After Gynecologic Cancer Surgery: A Meta-Analysis of Randomized Controlled and Observational Cohort Studies - Mdpi.com
Article by Maximos Frountzas, Ioannis Karavolias, Christina Nikolaou, Orsalia Toutouza et al. (Greece, UK - Cancers). The authors' meta-analysis demonstrated lower wound-related postoperative complications in patients treated with negative pressure wound treatment systems compared to conventional gauze after gynecologic oncologic surgery. Nevertheless, these comparisons did not reach statistical significance.

What specific challenges do patients with chronic wounds encounter when attending medical appointments related to wound care? A systematic review - Sciencedirect.com
Article by Krishi Jain, Pinar Avsar, Declan Patton, Zena Moore and Bridget Murray (J Tissue Viability). This systematic review identified several challenges faced by patients with chronic wounds when attending medical appointments. Key issues include increased waiting times, and the excessive cost of appointments. Pain, discomfort, and physical limitations further complicated attendance, particularly for distant clinics, leading to reliance on expensive private transport. Additionally, three studies reported decreased quality of life.

Convergence of biocompatible printed electronics and sensing in wound dressings: a leap forward in sustainable health monitoring - Nature.com
Article by Manoj Jose, Mani Teja Vijjapu, Lukas Neumaier, Lukas Rauter et al. (Belgium, Austria - npj Flexible Electronics). The review explores the potential of sustainable and biocompatible printed electronics in transducing wound biomarkers into actionable healing insights, enabling timely interventions. This work also provides a roadmap for printed electronics-based wound monitoring and on-demand treatment solutions, offering a glimpse into the future promises of the technology.

Modeling treatment of diabetic wounds with oxygen therapy and senolytic drug - Nature.com
Article by Nourridine Siewe and Avner Friedman (USA - Scientific Reports). In this paper the authors simulate treatments with HBOT and quercetin, separately or in combination, of diabetic wounds in aging population.

Measuring wound healing with gases - Nature.com
Abstract by Matthew Parker (Nature Electronics). The researchers — who are based at Northwestern University, the Korea Institute of Science and Technology, and the University of Illinois at Urbana-Champaign — suggest that the device chamber could cover an open wound, allowing inflammation and wound healing to be monitored via emitted VOCs, without directly touching the wound site.

Best practice recommendations for the prevention and management of skin tears in aged skin (2nd Edition) - Woundsinternational.com
Article by Emmy Nokaneng, Corey Heerschap, Debra Thayer, Karen Ousey et al. (Wounds). Skin integrity is key to wound prevention making prevention strategies and preservation of skin health of paramount importance. This updated guideline aims to provide all clinicians with the information and resources they need to prevent, assess, classify and treat skin tears in practice with confidence, improving patients’ overall skin health and outcomes.

The Role of Skin Substitutes in the Therapeutical Management of Burns Affecting Functional Areas - Mdpi.com
Article by Matei Iordache, Luca Avram, Ioan Lascar and Adrian Frunza (Bucharest, Romania - Medicina). This article aims to present and compare the most used skin substitutes, highlighting their respective advantages and limitations. This topic continues to be a subject of significant debate, as an ideal substitute has yet to be created. The cost–efficiency ratio is a practical consideration that must be tailored to each specific medical system.

A Scoping Review to Identify Clinical Signs, Symptoms and Biomarkers Reported in the Literature to Be Indicative of Biofilm in Chronic Wounds - Nih.gov
Article by John D Ivory, Laure Perrier, Akke Vellinga, Duygu Sezgin et al. (Ireland, Canada, Australia - International Wound Journal). The authors advocate that in the interests of optimising patient care and streamlining treatment strategies, a concerted effort to validate or nullify the reported signs and symptoms of biofilm in the literature be carried out and the findings of this scoping review could serve as an ideal starting point.

Polymeric Nanomedicines in Diabetic Wound Healing: Applications and Future Perspectives - Dovepress.com
Article by Zeyao Chen, Kakei Chan, Xin Li, Li Gong et al. (China - International Journal of Nanomedicine). This article systematically examines recent progress in PN-based interventions for diabetic wound recovery, highlighting the pivotal role of PNs in mitigating bacterial infection, modulating inflammatory responses, and promoting cellular regeneration.

New perspectives for wound healing and the treatment of chronic diseases - Idw-online.de
Fibroblasts play a central role in maintaining healthy tissue structures, as well as in the development and progression of diseases. For a long time, these specialised connective tissue cells were thought to represent a single, uniform cell type. A recent publication by researchers at the University of Leipzig Medical Center shows that fibroblasts in human tissue actually consist of distinct populations with specialised functions. This heterogeneity is key to developing targeted therapies in regenerative medicine and in the treatment of diseases.

Increased ROS and Persistent Pro-Inflammatory Responses in a Diabetic Wound Healing Model (db/db): Implications for Delayed Wound Healing - Mdpi.com
Article by Hanan Elajaili, Bailey D. Lyttle, Caitlin V. Lewis, James R. Bardill et al. (USA - IJMS). The authors' results suggest that elevated superoxide production and persistent inflammation contribute to impaired fibroblast function and delayed wound healing in diabetes.

Fibromodulin-overexpressing fibroblast cells increase wound contraction, improve scar quality and enhance angiogenesis: an in-vivo study - Biomedcentral.com
Article by Negar Abdollahzadeh, Mehran Vatanchian, Fatemeh Oroojalian, Seyed Ehsan Enderami, Amir Amani and Reza Salarinia (Bojnurd, Iran - BMC Biotechnology). The results of this study showed that fibroblast cells expressing the fibromodulin gene improve wound contraction and some histological parameters in the deep wound model of the rat.

Effectiveness of silver and iodine dressings on wound healing: a systematic review and meta-analysis - Bmj.com
Article by Yan Jiang, Qijian Zhang, Hongjuan Wang, Maritta Välimäki et al. (Changsha, China - BMJ Open). Silver dressings, demonstrating a comparable healing rate to iodine dressings, significantly reduce healing time, suggesting their potential as a superior adjunct in wound care.

Natural Bioactive Compound Loaded Nanomaterials for Wound Healing - Ijpsjournal.com
Article by Aniket Ade, Rushikesh Mahajan, Pranjal Aher, Khanderao Jadhav and Rishikesh Bacchav (Anjaneri, India - International Journal of Pharmaceutical Sciences). This review critically explores the role of natural bioactive compound-loaded nanomaterials in wound healing, focusing on their mechanisms of action, types of bioactive compounds, and their Nano formulation strategies.

Integral Debridement Throughout the Continuum of Care - Woundsource.com
In this roundtable interview, Karen Bauer, Amanda Murray and Micah Siegel share their experiences and top pearls for incorporating integral debridement into clinical practice.

Integral Debridement for Complex Wounds: An Expert’s Insights - Woundsource.com
Article by Mary Anne R. Obst. Wound bed preparation is a critical component of wound healing. This blog provides an overview of the process of removing necrotic tissue, controlling infection, and promoting an environment conducive to tissue regeneration.

Controlled Intervention Study on Effects of an AI-Based App to Support Wound Care: First Results - PubMed
Abstract by Hannah Pinnekamp, Vanessa Priester, Alexander Brehmer and Uli Fischer (Germany - Stud Health Technol Inform.).

Advanced Wound Care Strategies in Patients with NSTIs - Mdpi.com
Article by Taylor Miller and Jaclyn Clark (Baltimore, USA - JCM). This review seeks to support generalist and acute care surgeons with the knowledge needed to optimize wound healing, enhance functional outcomes, and improve quality of life for necrotizing soft tissue infections (NSTI) survivors.

Impact of postoperative dairy consumption on oral wound healing: critical analysis from a prospective, randomized and controlled trial - Biomedcentral.com
Article by Tobias Otto, Jan Alfred Dittmann, Jacob Stake, Dirk Szulczewski-Stake et al. (Germany - Head & Face Medicine ). The study found no statistically significant associations that dairy product consumption has either a negative or positive effect on wound healing.

Topical metformin in wound healing: a comprehensive systematic review of therapeutic outcomes - PubMed
Abstract by Dorian Maghsoodloo, Hamed Zartab, Milad Alipour, Mohammad Rezaei Zadeh Rukerd et al. (Tehran, Iran - Arch Dermatol Res.).

Comparison and evaluation of negative pressure wound therapy versus standard wound care in the treatment of diabetic foot ulcers - Biomedcentral.com
Article by Quan Guo (Yongzhou, China - BMC Surgery). NPWT is more superior in safety, cost-efficiency, and long-term wound management compared to SWC.

Hemodialysis pathway types influence wound healing complications and survival in end-stage renal disease patients in a retrospective cohort study - Nature.com
Article by Jie Ding and Jun Li (Wuhan, China - Scientific Reports). The authors' findings suggest that while autologous arteriovenous fistula provides superior dialysis efficiency and survival outcomes with fewer complications, patient suitability and individual health conditions must be carefully considered when selecting the appropriate vascular access for hemodialysis.

New generation of skin substitutes give hope to severe burns patients - Sciencedaily.com
Australian researchers have flagged some promising new approaches to treat severe burns that could save lives and dramatically improve patient recovery.

Does Wound Repair of Traumatic Lacerations After the “Golden Period” Increase Poor Wound Outcomes? - Clinicaladvisor.com
Article by Tou Xiong. Traumatic lacerations are a common condition seen in the emergency department (ED), accounting for approximately 8% of visits or an estimated 7 to 9 million lacerations treated each year. There are various methods used for primary wound closure, including sutures, staples, surgical tape, and tissue adhesives. The type of closure will largely depend on the location of injury, size of laceration, depth of the wound, and other marginal factors such as the complexity of wound edges and wound tension.

Safety and tolerability of kinesiotaping as add-on treatment of pressure injuries - PubMed
Abstract by Paola Paglierani, Debora Donatini, Elisa Maietti, Paola Rucci et al. (Italy - J Wound Care).

Biomedical Application of Nanogels: From Cancer to Wound Healing - Mdpi.com
Article by Mohammad Zafaryab and Komal Vig (Montgomery, USA - Molecules). Researchers are looking for novel alternative approaches, as foreign microorganisms in wounds are becoming resistant to antibiotics. Silver nanogels have been reported as a popular antimicrobial choice, as silver has been used as an antimicrobial throughout a prolonged period.

Gold Nanoparticle-Based Hydrogel: Application in Anticancer Drug Delivery and Wound Healing In Vitro - Mdpi.com
Article by Varshan Gounden and Moganavelli Singh (Durban, South Africa - Pharmaceutics). The positive findings from this study confirm the potential of these CS-Au hydrogels to function as smart in vitro delivery systems and scaffolds for wound healing, warranting additional optimizations and in vivo studies.

Risk factors and prevalence of medical device-related pressure injuries in pediatric intensive care - PubMed
Abstract by Müge Seval, Emine Uzuntarla Güney, Tülay Kuzlu Ayyıldız and Nazife Şirin Kuzlu Alkan (Turkey - J Pediatr Nurs.)

Nanoformulations Loaded with Phytochemicals for Combating Wound Infections and Promoting Wound Healing: Current Applications and Innovations - Mdpi.com
Article by Panoraia I. Siafaka, Androulla N. Miliotou, Mehmet Evren Okur, Gökçe Karaotmarlı Güven et al. (Cyprus, Turkey - Applied Sciences). This review summarizes the most current advanced applications combining phytochemicals and nanoformulations with promising wound healing potential. Various nanosystems loaded with phytochemicals have been identified, such as silver nanocarriers, zein-based nanoparticles, and various known polymers, which can be utilized to develop electrospun fibrous structures loaded with phytoremedies.

AMP-IBP5: A Multifunctional Antimicrobial Peptide for Advanced Wound Healing and Inflammatory Skin Disorders - Mdpi.com
Article by Alafate Abudouwanli,Ge Peng, Mengyao Yang, Wanchen Zhao et al. (Japan, China - JFB). This review delves into the broad therapeutic potential of AMP-IBP5 across dermatological applications, focusing on its intricate mechanisms of action, comparative advantages, and its path toward clinical and commercial application.

Formulation And Evaluation of Guar Gum Gel for Wound Healing - Ijpsjournal.com
Article by Neha Rathod, Shivani Wankhade, Aditi Tikait, Swati Deshmukh and Ajip Rathod (Maharashtra, India - International Journal of Pharmaceutical Sciences). The authors' results suggest that the formulated guar goo gel is a promising natural crack mending agent with eventuality for clinical operations.

In Vitro Analysis of Healing Properties of Platelet-Rich Fibrin (PRF) vs. Collagen Membranes in Guided Tissue Regeneration - Lww.com
Article by B. Saravana Kumar, Ushma H. Prajapati, Neelam Das, K. Vel Latha et al. (India - Journal of Pharmacy and Bioallied Sciences). The authors' results suggest that PRF might be a more effective biomaterial for use in guided tissue regeneration.

Biodegradable Double-Layer Hydrogels with Sequential Drug Release for Multi-Phase Collaborative Regulation in Scar-Free Wound Healing - Mdpi.com
Article by Xinyu Zhang, Qianhe Zu, Chunlin Deng, Xin Gao et al. (Baoding, China - JFB). This innovative approach lays a promising foundation for future clinical applications in anti-scar therapies, offering a significant advancement in wound care and regenerative medicine.

Integral Debridement in the Postoperative Setting: An Expert’s Perspective - Woundsource.com
Article by Abigail E. Chaffin. As integral debridement gains wider acceptance, and additional integral debridement technologies are developed, further research is needed to refine protocols and evaluate long-term outcomes. Ongoing studies are building on the already wide evidence base of the role of novel debridement adjuncts, including existing and emergent enzymatic debridement agents, to further enhance wound bed preparation.

Effect of Hyaluronan in Collagen Biomaterials on Human Macrophages and Fibroblasts In Vitro - Mdpi.com
Article by Nancy Avila-Martinez, Maren Pfirrmann, Madalena L. N. P. Gomes, Roman Krymchenko et al. (The Netherlands, JFB). The authors' findings highlight the potential of incorporating hyaluronan into collagen-based skin substitutes to improve the wound healing response.

Implementing Wound Balance: Outcomes and future recommendations - Woundsinternational.com
Article by Harikrishna K. R. Nair, Karen Ousey, Trent Brookshier, Emmanuelle Candas et al. (Wounds). Non-healing wounds can reduce quality of life (QoL) for millions of people globally, are costly, and result in significant patient, clinician and healthcare system burden. There is a significant need to proactively address the projected rise of non-healing wounds by earlier intervention, resource optimisation and patient-centred care. The concept of ‘Wound Balance’ developed in 2023 can help address these unmet needs (Wounds International, 2023). Wound Balance aims to create a holistic picture of the patient and their wound so clinicians can achieve a balance between the many facets of wound care planning and achievable goals.

Multifunctional Carbon-Based Nanocomposite Hydrogels for Wound Healing and Health Management - Mdpi.com
Article by Tianyi Lu, Yaqian Chen, Meng Sun, Yuxian Chen et al. (China - Gels). This review may provide some new inspirations for the future development of carbon-based nanomaterials in wound care and tissue engineering.

TWEAK regulates the functions of hair follicle stem cells via the Fn14-Wnt/β-catenin-CXCR4 signalling axis - Wiley.com
Article by Xiaoyan Zou, Yaning Tian, Lingling Peng, Mai Luo et al. (China - Wound Repair and Regeneration). Targeting the Fn14-Wnt/β-catenin-CXCR4 signalling axis may offer a potential approach for managing hair follicle stem cells-related skin diseases, such as wounds.

Efficacy of xenogeneic fresh and lyophilized amniotic membranes on the healing of experimentally induced full-thickness skin wounds in dogs - Nature.com
Article by Kamal H. Hussein, Esraa Motiea and Manal T. Hussein (Assiut, Egypt - Scientific Reports). The amniotic membrane, particularly in its lyophilized form, offers significant benefits for skin wound healing due to its bioactivity, availability, and cost-effectiveness.

Current State and Advances in Antimicrobial Strategies for Burn Wound Dressings: From Metal-Based Antimicrobials and Natural Bioactive Agents to Future Perspectives - Mdpi.com
Article by Andrea Osmokrovic, Jasmina Stojkovska, Tanja Krunic, Predrag Petrovic et al. (Belgrade, Serbia - IJMS). This review aims to provide a valuable resource for clinicians, researchers, and innovators seeking to improve outcomes in burn wound management.

Sustainable Wound Management in the Tropics: An Innovative Look at Village Practices - Woundsource.com
Article by Kirra Fedyszyn. A poster presented at the Symposium on Advanced Wound Care (SAWC) Spring 2025 outlines an innovative approach to understanding how health care practitioners in rural tropical villages approach wound care and how sustainable, validated wound care strategies can help bridge gaps.

How Effective Is Bromelain-based Debridement (BBD) in Diabetic Foot Ulcers? - Woundsource.com
Article by Brian McCurdy. Bromelain-based debridement is advantageous compared to debridement via gel vehicle, according to this poster presented at SAWC Spring, which compared the procedures in terms of debridement, granulation tissue promotion, and wound closure for diabetic foot ulcers.

Antibacterial Properties of Bioactive Compounds in Chronic Wounds - Woundsource.com
Article by Jennifer J. Spector. A recent study assessed the effects of 4 different bioactive wound healing materials against 3 prevalent bacterial pathogens associated with chronic wounds to identify potentially optimal wound dressing compositions to improve infection and biofilm management.

Innovative Sericin-Based Film-Forming Gel for Wound Healing: Development and Performance Evaluation - Mdpi.com
Article by Suprawee Wongtechanon, Chayanee Noosak, Pavarish Jantorn, Papitchaya Watcharanurak et al. (Thailand, Polymers). The F4 formulation (1% sericin) demonstrated superior performances in drying time, spreadability, stability, swelling ratio, flexibility, and skin adhesion, was easy to apply, and formed a stable film on drying. Biological evaluations showed that F4 exhibited excellent compatibility with skin fibroblast cells, maintained a suitable pH, and significantly promoted cell proliferation and migration.

Effects of Extracorporeal Shockwave Therapy on Wound Healing in Rats - Cureus.com
Article by Takuro Sugiyama, Hidetaka Murakami, Shinichiro Tanaka, Shiro Yoshida et al. (Japan). The authors' findings suggest that extracorporeal shockwave therapy may enhance early wound healing by promoting angiogenesis and collagen production.

Frequency-Specific Sound Enhances Tissue Regrowth - Dermatologytimes.com
Article by Maddi Hebebrand. Acoustic stimulation using infrasound and low-frequency sound enhances wound healing, promoting cellular activity and tissue repair in innovative, non-invasive ways.

Decoding Macrophage Dynamics: A Pathway to Understanding and Treating Inflammatory Skin Diseases - Mdpi.com
Article by Shengliang Gu, Lei Xu, Bin Huang, Kai Xiong et al. (China - IJMS). This article summarizes the roles of macrophages in the inflammatory development and tissue homeostasis of psoriasis and atopic dermatitis.

Impact of malodour on health-related quality of life of patients with chronic wounds due to volatile organic compounds - Wiley.com
Article by E. K. Stuermer, C. Nathrath, H. Lober, M. Wigger et al. (Germany - Wound Repair and Regeneration). The malodour of chronic wounds is caused by a mixture of the intrinsic odour of bacterial products and necrosis. This exploratory study, which combines the analysis of decoded volatile organic compounds and the olfactory assessment of odour, could be a novel, targeted approach for identifying potential ‘anti-wound odour therapies’ that will significantly benefit the health-related quality of life of patients with malodourous tumour wounds, in particular.

Our wounds heal slower than the cuts and scrapes of other primates - Newscientist.com
Article by Chris Simms. Human wounds take almost three times as long to heal as the injuries of other mammals, including chimpanzees, which are among our closest living relatives. It isn’t clear why, but it may be an evolutionary adaptation connected to the loss of most of our body hair.

Effect of active wound dressing on postoperative pain and wound healing in patients undergoing anorectal surgery - Biomedcentral.com
Article by Guangyuan Qie, Miao Wan, Mengdie Cui, Wen Xia and Qianqian Liu (Shanghai, China - BMC Gastroenterology). Active wound dressing has been shown to alleviate postoperative pain in patients undergoing AS, promote wound healing, and effectively regulate levels of growth factors and inflammatory factors.