Hungarian Wound Care Society

PI Education for Older Adults and Their Caregivers: What Gaps Exist? - Woundsource.com
This blog provides a summary of a recent scoping review that evaluated how pressure injury prevention programs are presented to patients and their caregivers.

Aberrances of the Wound Healing Process: A Review - Mdpi.com
Article by Montserrat Fernandez-Guarino, Jorge Naharro-Rodriguez and Stefano Bacci (Spain, Italy - Cosmetics). This review highlights the distinct mechanisms underlying chronic wounds, keloids, and hypertrophic scars and discusses their respective therapeutic approaches, focusing on both established and emerging therapies. Understanding these mechanisms is crucial for optimizing treatment strategies and improving patient outcomes.

Critical Analysis of Cytoplasmic Progression of Inflammatory Signaling Suggests Potential Pharmacologic Targets for Wound Healing and Fibrotic Disorders - Mdpi.com
Article by Michael L. Samulevich, Liam E. Carman and Brian J. Aneskievich (Stors, USA - Biomedicines). Current findings support further intensive studies of the mentioned points in NF-κB regulation both for their basic function in healthy cells as well as with the goal of targeting them for translational benefit in multiple cutaneous wound healing situations, whether stemming from acute injury or a dysregulated inflammatory/fibrotic response.

Time Heals All Wounds: Probing Skin Injuries with Spatial Biology - The-scientist.com
Discover how spatial transcriptomics and proteomics advance wound healing research.

Patient Experience and Wound Healing Outcomes Using Different Palatal Protection Methods After Free Gingival Grafts: A Systematic Review - Mdpi.com
Article by Tomasz Jankowski, Agnieszka Jankowska, Mirona Palczewska-Komsa, Maciej Jedliński et al. (Poland - JFB). Most studies in this review examined platelet-rich fibrin and suggested that it provides no benefits for patients’ subjective experiences or wound healing outcomes. While photobiomodulation appears to support wound epithelialization, it does not influence pain perception.

Expediting Acute Wound Healing by Integrating Multiple Therapeutic Strategies: A Case Series - Hmpgloballearningnetwork.com
Article by Kathy E. Gallagher, Emily C. Alberto, John Getchell, Jessie Powell and Luis Cardenas (Newark, USA - Wound Management & Prevention). Optimizing advanced therapeutic combinations with innovative dressings, including pHA and other beneficial components, has shown reduced health care utilization of acute wound patients by shortening healing time. The resulting decrease in dressing changes, follow-up appointments, and home care could increase patient satisfaction and improve outcomes.

Impact of solution-focused brief therapy and vacuum sealing drainage on mental health of wound care patients - Wjgnet.com
Article by Wen-Juan Shi, Jian Zhou, Qi-Liang Xu, Yi Jiang and Qiang Dai (Liyang, China - World J Psychiatry). The combination of SFBT and NPWT accelerates wound healing, promotes granulation tissue growth, and improves psychological well-being, making it a valuable approach for clinical application.

Activity of Sea Cucumber and Spirulina in Wound Healing and Blood Glucose Decreasing in Streptozotocin- Induced Diabetic Rats - Bio-conferences.org
Article by Hendra Susanto, Mega Safithri, Kustiariyah Tarman and Iriani Setyaningsh (Bogor, Indonesia - BIO Web of Conferences ). The results showed that group of golden sea cucumber orally-topically had the best antihyperglycemic activity with the highest percentage reduction in blood glucose level while group of golden sea cucumber topically-spirulina orally had the best wound healing effect with the highest percentage of wound healing.

Exploration of the Topical Nanoemulgel Bearing with Ferulic Acid and Essential Oil for Diabetic Wound Healing - Mdpi.com
Article by Urati Anuradha, Valamla Bhavana, Padakanti Sandeep Chary, Nitin Pal Kalia and Neelesh Kumar Mehra (Telangana, India - Pathophysiology). The authors' findings indicate that FA-loaded nanoemulgel greatly accelerates the healing of wounds in diabetic rats.

Managing Wound Complications After Osteosarcoma Resection: Stopping Adjuvant Therapy and Performing Secondary Closure - Cureus.com
Article by Kiichi Furuse, Daisuke Kageyama, Masaki Arikawa, Satoshi Akazawa and Takuya Higashino (Japan). Managing wound complications after OS resection requires balancing the completion of adjuvant chemotherapy (AC) with effective limb salvage strategies. Deciding on temporary suspension of AC without delay and secondary closure is important.

Promotion of chronic wound healing by plant-derived active ingredients and research progress and potential of plant polysaccharide hydrogels - Sciencedirect.com
Article by Ru Yan, Yanhong Wang, Weinan Li and Jialin Sun (Harbin, China - Chinese Herbal Medicines). The article delves into the latest advancements in clinical and experimental research on the impact of active constituents in herbal medicine on wound tissue regeneration, summarizing existing studies on the mechanisms of various herbal medicines in the healing of diabetic and burn wounds.

Non‐invasive techniques for wound assessment: A comprehensive review - Nih.gov
Article by Chunlin Zhao, Yuchen Guo, Lingli Li and Mei Yang (Chengdu, China - International Wound Journal). This paper aims to review the various methods of measurement and diagnosis based on non‐invasive wound imaging, and to summarize their application in wound monitoring and assessment.

How AI In Wound Care Can Improve Patient Outcomes - Woundzoom.com
AI wound care enhances patient outcomes by automating processes that previously required manual observation and intervention. Through machine learning algorithms and data-driven insights, AI tools can provide clinicians with more precise information, leading to better decision-making. This article examines the key ways in which AI is transforming wound care and how these advancements directly benefit patients.

Passive Movement Exercise of the Lower Limbs May Facilitate Wound Healing in Patients With Diabetic Foot Ulcers - Cureus.com
Article by Tue Smith Jørgensen, Amalie Schramm, Maria Leinum, Hans Gottlieb et al. (Denmark). The two-leg passive movement intervention showed a non-significant difference in wound healing and was well tolerated by patients with diabetic foot ulcers. Although the study shows potential, the results should be interpreted with its limitations of being underpowered and potentially confounded.

Could a Digital Notification System Improve the Consequences of Ostomy Leakage? - Woundsource.com
Data from a recent clinical trial aimed to address a common concern for patients with ostomies; managing leakage of stomal effluent. This United Kingdom-based study took a closer look at a digital leakage notification system for those with an ostomy.

Cellular and molecular roles of reactive oxygen species in wound healing - Nature.com
Article by Matthew Hunt, Monica Torres, Etty Bachar-Wikstrom and Jakob D. Wikstrom (Stockholm, Sweden - Communications Biology). In this review, the authors highlight current knowledge of the discussed functions, and highlight the potential future direction of new studies, and how these pathways may be targeted in future pre-clinical studies.

Wound Healing Potential of Herbal Hydrogel Formulations of Cedrus brevifolia Extracts in Mice - Mdpi.com
Article by Georgia Lyggitsou, Christina Barda, Maria Anagnostou, Andreas Douros et al. (Athens, Greece - Gels). This study aims to investigate the potential of C. brevifolia resin and bark extracts in promoting wound healing in a mouse model.

Erase the trace: New frontiers in scar prevention and skin repair - Eurekalert.org
In a study published in the journal Biofunctional Materials, researchers review different types of scars along with their various aspects and existing treatment options. New therapies that have the potential to reduce scar formation through skin regeneration were explored, in an effort to prevent scarring in the future.

3D Printing-Based Hydrogel Dressings for Wound Healing - Wiley.com
Article by Xuan Zhou, Xunzhou Yu, Tingting You, Baohua Zhao et al. (Chongqing, China - Advanced Science). The application of multi-functional 3D printing-based hydrogel dressings in a variety of wound environments is discussed in depth, including hemostasis, anti-inflammation, antibacterial, skin appendage regeneration, intelligent monitoring, and machine learning-assisted therapy.

Comparative Evaluation of Wound Healing Efficacy (of Bombyx mori L. Body Extracts, Gland Extracts, and Cocoon for the Treatment of Second-Degree Burns: A Pilot Study - Mdpi.com
Article by Alexandra Kyriaki, Margarita Vidali, Andreas Vitsos, Paschalis Harizanis et al. (Athens, Greece - Processes). This novel insight into the therapeutic properties of silkworm body extracts opens new opportunities for the development of cost-effective, renewable second-degree burn healing treatments.

Natural Product for Wound Healing: Systemic Review - Saudijournals.com
Article by Junaidu Mustapha (Greater Noida, India - Saudi J Med Pharm Sci). The field of herbal medicine and other natural products are used in traditional and alternative medicine to treat wounds. These methods have various benefits over conventional treatments, such as enhanced efficacy owing to different ways in which they work action, antibacterial qualities, and long-term safety when using wound dressings.

Advanced Secondary Intention Healing for Complex Soft-Tissue Defects Using Reprocessed Micronized Acellular Dermal Matrix - Mdpi.com
Article by Ha Jong Nam, Dong Gyu Kim, Je Yeon Byeon, Da Woon Lee et al. (Republic of Korea - Life). No significant correlations were observed between patient variables and wound-healing outcomes, indicating the complex nature of wound healing. mADMs effectively promote secondary intention healing by providing a supportive extracellular matrix scaffold that enhances epithelialization and angiogenesis.

A novel method to assess photobiomodulation in stimulating regenerative capacity and vascularization in zebrafish - Wiley.com
Article by Afnan Sedky Adly, Jean-Christophe Egea, Mahmoud Sedky Adly, Ivan Panayotov et al. (Montpellier, France - Wound Repair and Regneration). This study presented a novel, simple and inexpensive method for the assessment of PBM effects on zebrafish. Laser and ultraviolet therapy appeared to act as regenerative stimulators for caudal-fin regeneration of zebrafish.

Autologous cell therapy for ischemic diabetic foot: a meta-analysis of randomized controlled trials for the development of the Italian guidelines for the treatment of diabetic foot syndrome - PubMed
Abstract by Alessia Scatena, Matteo Apicella, Michele Mantuano, Benedetta Ragghianti et al. (Italy - Acta Diabetol.).

Research Progress on the Application of Natural Medicines in Biomaterial Coatings - Mdpi.com
Article by Yanchao Wang, Huimin Duan, Zhongna Zhang, Lan Chen and Jingan Li (Zhengzhou, China - Materials). This paper summarizes some suggestions by evaluating the literature, such as optimizing the binding method and release system; carrying out more clinical application research; carrying out multidisciplinary cooperation; broadening the application of natural medicine in biomaterial coatings; and developing safer, more effective and multi-functional natural medicine coatings through continuous research and innovation, so as to contribute to the development of the biomedical field.

How Nanoparticles Help in Combating Chronic Wound Biofilms Infection? - Dovepress.com
Article by Gang Jing, Chen Hu, Keyi Fang, Yingying Li and Linlin Wang (Haikou, China - International Journal of Nanomedicine). Nanoparticles represent a promising strategy for combating chronic wound biofilm infections, and this review provides new insights for alternative adjuvant therapies in managing bacterial biofilm infections in chronic wounds.

The efficacy of cellulose dressings in burn wound management: a systematic review and meta-analysis - Sciencedirect.com
Abstract by Tristan Hill, Abdal Qadir Zafar, Tal D Ellenbogen, Neil C Mathias et al. (Leeds, UK - Burns).

How a fish could lead to new hope for treating persistent wounds - Pitt.edu
Zebrafish, though small and unassuming, are valued in biomedical research because they share many genetic similarities with humans, are easy to maintain and can be engineered to glow in the presence of certain molecules. That makes them excellent “living sensors,” ideal for screening compounds for potential biological effects.

The Role of Biomechanical Forces in the Formation and Treatment of Pathological Scars - Dovepress.com
Article by Guangtong Cao, Mingmin Ye, Haiyan Wang, Yi Liu and Mengzhi Li (China - Clinical, Cosmetic and Investigational Dermatology). This review highlights the role of biomechanical forces in scar formation and discusses therapeutic approaches that target these forces to improve clinical outcomes.

Collagen-Based Nanoparticles as Drug Delivery System in Wound Healing Applications - Tandfonline.com
Article by Kusnadi Kusnadi, Yedi Herdiana, Emma Rochima, Okta Nama Putra et al. (Indonesia - International Journal of Nanomedicine). The use of collagen-based NPs presents a compelling strategy for expediting wound healing processes.

The healing process of diabetic ulcers correlates with changes in the cutaneous microbiota - Nature.com
Article by Emanuele Bruni, Giovanni Luca Scaglione, Denise Tampone, Alessia Primerano et al. (Rome, Italy - Scientific Reports). The authors' data indicate that in the absence of antibiotic-based therapy the healing process of diabetic ulcers is accompanied by changes in the microbiome composition.

Maggots in Medicine: A Narrative Review Discussing the Barriers to Maggot Debridement Therapy and Its Utilisation in the Treatment of Chronic Wounds - Natre.com
Article by Zoe Mumford and Yamni Nigam (Swansea, UK - JCM). The findings of this review suggest that maggot debridement therapy is an underused and potentially very effective method of debridement compared to conventional treatments. The identified barriers could be mitigated with relatively low-cost solutions.

Marine Resources Gels as Main Ingredient for Wound Healing Biomaterials: Obtaining and Characterization - Mdpi.com
Article by Kay Hon, Madeleine Bain, Georgina Minns, Eliza Colley and Robert Fitridge (Adelaide, Australia - AJGP). Article by Alina Elena Coman, Maria Minodora Marin, Ana Maria Roșca, Madalina Georgiana Albu Kaya et al (Bucharest, Romania - Gels). The outcomes reveal an innovative path for the production of biomaterials used in wound healing, starting from collagen derived from marine sources.

Conservative management of patients with end-stage chronic limb-threatening ischaemia in the community - Racgp.org.au
Article by Kay Hon, Madeleine Bain, Georgina Minns, Eliza Colley and Robert Fitridge (Adelaide, Australia - AJGP). This review article aims to provide general practitioners with an overview of conservative management of patients with end-stage CLTI in the community.

PI Education for Older Adults and Their Caregivers: What Gaps Exist? - Woundsource.com
The authors shared that they recommend a multi-pronged approach to education on PIs for this patient population. They feel the education should be continuous, providing support over extended periods of time. Additionally, they recommended that these efforts begin at the level of primary care providers as part of a comprehensive approach to their overall health.

What Factors Contribute Most to Peristomal Skin Complications? - Woundsource.com
Peristomal skin complications (PSCs) may arise after ostomy creation, and a recent systematic review and meta-analysis in Wound Management and Prevention took a closer look at what factors may influence this occurrence.

Innovative biopolymers composite based thin film for wound healing applications - Nature.com
Article by Majid Ali, Shakir Ullah, Shaker Ullah, Muhammad Shakeel et al. (Pakistan, Saudi Arabia, Germany - Scientific Reports). The authors' findings suggest its potential for further investigation in treating various infections and its role in developing novel therapeutic interventions.

Engineered, Radially Aligned, Gradient-Metformin Eluting Nanofiber Dressings Accelerate Burn-Wound Healing - Dovepress.com
Article by Shih-Heng Chen, Hsiao-Jui Kuo, Pang-Yun Chou, Chia-Hsuan Tsai et al. (Taoyuan, Taiwan - International Journal of Nanomedicine). The findings in this study emphasize the potential of resorbable, radially aligned nanofiber dressings as advanced wound care solutions, offering broad applicability and meaningful clinical impact.

Characterizing Fibroblast Heterogeneity in Diabetic Wounds Through Single-Cell RNA-Sequencing - Mdpi.com
Article by Helen H. Wang, Maria Korah, Serena L. Jing, Charlotte E. Berry et al. (Stanford, USA - Biomedicines). The authors summarize recent research on the role of fibroblasts in diabetic wound healing and describe the functional and cellular heterogeneity of skin fibroblasts.

Postoperative wound surveillance using patient smartphones: Learning from a large London maternity service - Wounds-uk.com
Article by Melissa Rochon, Karen Cariaga, Sean Derick Ingusan, Angila Jawarchan et al. (Wounds). The integration of digital surveillance technologies for post-discharge monitoring of SSIs following C-sections represents a significant advancement in maternal healthcare. SSIs remain a considerable challenge post-C-section, impacting not only the physical health of new mothers but also their psychological wellbeing and the broader healthcare system.

Refrigerated amniotic membrane maintains its therapeutic qualities for 48 hours - Frontiersin.org
Article by J. Stelling-Férez, J. M. Puente-Cuadrado, V. Álvarez-Yepes and S. Alcaraz (Murcia, Spain - Front. Bioeng. Biotechnol.). The authors' data suggest that the handling method in saline solution at 4°C does not interfere with amniotic membrane’s therapeutic properties.

Solascure and U.S. Army Institute of Surgical Research collaborate for combat wound care - News-medical.net
SolasCure Ltd., a biotechnology company developing a novel treatment to transform chronic wound care and the U.S. Army Institute of Surgical Research ("USAISR"), today announced a research collaboration to evaluate SolasCure's investigational product, Aurase Wound Gel, as a means for managing combat wounds. Aurase Wound Gel is a hydrogel releasing tarumase, a recombinant enzyme derived from medical maggots, which is currently being developed to promote wound healing through debridement and wound bed preparation.

Closed-incision negative pressure wound therapy (NPWT) in elderly patients following sacral pressure sore reconstruction - Biomedcentral.com
Article by Ji Won Jeong, Seungkeun Lee and Jun Ho Park (Republic of Korea - BMC Geriatrics). Closed-incision negative pressure wound therapy (CI-NPWT) shows promise in reducing wound dehiscence and infection rates in elderly patients undergoing sacral pressure sore reconstruction with local flaps.

Hyaluronic Acid Combined with Ozone in Dental Practice - Mdpi.com
Article by Alessio Rosa, Alberto Maria Pujia and Claudio Arcuri (Rome, Italy - Biomedicines). The authors' results indicate that the use of topical HA in combination with ozone therapy is highly effective not only in promoting post-operative healing following dental procedures but also in providing positive outcomes for individuals dealing with chronic gingivitis, periodontal inflammation, and oral ulcers.

Regeneration of tissue damage and the challenge of recruiting the building blocks for repair - Springernature.com
Article by Jenny Kretzschmar (UK). Tissue damage increases the demand for resources. But how does the metabolism adapt to these increased needs? Using fruit fly and axolotl as model organisms, we uncover a remarkable plasticity in systemic lipid turnover upon injury, allowing the effective repair of damaged tissues.

Nanoparticle-Based Therapeutics for Enhanced Burn Wound Healing: A Comprehensive Review - Dovepress.com
Article by Shaoyan Shi, Xuehai Ou, Jiafeng Long, Xiqin Lu et al. (Xi’an, China - International Journal of Nanomedicine). Various nanoparticles, such as metal-based, polymer-based, and extracellular vesicles, are evaluated for their distinctive properties and mechanisms of action, including antimicrobial, anti-inflammatory, and regenerative effects.

A new portable negative pressure wound therapy device: a prospective study investigating clinical outcomes - Magonlinelibrary.com
Article by Victoria Rose, Nadine Hachah Haram and Sarah Gallala (UK, Belgium - Journal of Wound Care). In this study, the suNPWT system supported the healing of closed surgical incisions with no safety concerns relating to its use.

Human keratin matrix in addition to standard of care accelerates healing of venous ulcers: a case series - Magonlinelibrary.com
Article by George Koullias and Allison N Ramey-Ward (USA - Journal of Wound Care). The results of this series highlight the potential of human keratin matrix, in combination with indicated systemic interventions and standard of care, as an effective treatment for hard-to-heal (chronic) VLUs, even in very large wounds.

The role of neuropeptides in cutaneous wound healing: a focus on mechanisms and neuropeptide-derived treatments - Frontiersin.org
Article by Liwei Xing, Bing Chen, Yuliang Qin, Xinyao Li et al. (Kunming, China - Front. Bioeng. Biotechnol.). The review discusses the process of wound healing, types of neuropeptides, potential mechanisms underlying the role of neuropeptides in cutaneous wound healing, as well as some neuropeptide-derived treatment strategies, such as hydrogels, new dressings, electro stimulation, and skin-derived precursors.

Preventing Scar Formation - News-medical.net
Article by Yolanda Smith. The formation of a scar is a natural part of the healing process following an injury to the skin as the body repairs the wound. The appearance of the scar after the area has healed depends on several factors including the type of injury, the area of the body affected, and the healing process itself.