Clean Versus Sterile: Management of Chronic Wounds - Lww.org
Abstract by Andrew Storer, Susan Cali, Kaitlin Denson, Lindyce Kulik et al. (USA - JWOCN).
Reactive Oxygen Species Counteract Wound Contraction and Promote Wound Healing - Biorxiv.org
Abstract by Chang Ding, Linlin Li, Yueyang Wang, Hong-Anh A Nguyen et al. (West Lafayette, USA).
Skin and Wound Healing: Conventional Dosage versus Nanobased Emulsions Forms - Acs.org
Article by João Vitor Vicente-da-Silva, Juliana Oliveira da Silva Lopes Pereira, Flávia Almada do Carmo and Beatriz Ferreira de Carvalho Patricio (Rio de Janeiro, Brazil - ACS Omega).
The authors discuss the skin function and wound healing process, highlighting the cellular and molecular processes, the different wound classifications, and factors that affect physiological healing.
Activities of Daily Living Model: Application to person-centred wound care - Wounds-uk.com
Article by Samantha Holloway.
By considering the activities of daily living and the factors influencing them healthcare professionals can create a comprehensive and more individualised care plan for patients with wounds which addresses all aspects of a patient’s life, promoting better outcomes and overall wellbeing.
A case study to explore the perspectives of tissue viability nurse specialists working in a community healthcare setting in the southeast of England, regarding the effect that psychological stress has on wound healing - Wounds-uk.com
Article by Laura Lodge and Debbie Reed.
This project demonstrated a consensus of opinion from the participants that if patients are not assessed holistically to identify a potential psychological impact of living with a wound, then this might affect the wound healing process. This was corroborated by earlier literature. The use of psychological tools is required when assessing wounds to help with ongoing frustrations associated with wound healing, which, in turn, will engage patients in their healing journey.
Sustaining improved patient outcomes in the reduction of wound infections through implementing evidence-based care into practice - Wounds-uk.com
Article by Kelly Phillips.
Evidence-based decision-making through critical appraisal of research evidence that is available in the field required, combined with user experience and local evaluation and has enabled evidence-based decision-making to be followed. Introducing evidence-based decisions into the local formulary and clinical pathways, supported by education, has enabled patient outcomes to be improved through a reduction in wound infections. By continuous review of the evidence and process, through research review, evaluations and audits, the impact of the decision and sustained improvement has been quantified, assuring that evidence-based decision-making was achieved and is successful.
Wound Healing in Human Skin Equivalents Reconstructed with Biopolymers Under Fine-Dust Exposure - Mdpi.com
Article by Taeeun Kim, Junwoo Lim, Jaehyun Jeong and Heewook Ryu (Seoul, South Korea - Polymers).
The authors revealed that fine-dust exposure significantly delayed wound closure by 2–3 times compared with unexposed controls, impairing re-epithelialization. Live imaging of wound-healing dynamics revealed that trace-metal-containing particles had a more pronounced inhibitory effect than polycyclic aromatic hydrocarbons.
Blood Plasma in Wound Healing: Breakthrough or Hurdle? - Emjreviews.com
Blood plasma, fibrinogen, and fibrin have long been explored for their role in skin tissue engineering and dermatological treatments, with promising preclinical results—but clinical adoption remains limited. A new systematic review evaluates 147 preclinical and 17 clinical studies to assess the effectiveness of these biomaterials in treating various skin conditions, from surgical wounds to severe burns.
Evaluating the Use of a Skin Failure Indicator Scale in the Diagnosis of Acute Skin Failure - Hmpgloballearningnetwork.com
Article by Jessica N. Fields, Hilary Hancock, Jeffrey W. Shupp and Shawn Tejiram (Washington, USA - Wounds).
Twelve patients who were identified has having hospital-acquired pressure injuries (HAPIs) were reclassified as having skin failure using the SFCIS. Further work is necessary to validate this scoring system in diagnosing skin failure and the implications associated with its use.
Microneedles accelerate diabetic wound healing in preclinical models - News-medical.net
Diabetic wounds often lead to severe complications that can result in amputations. These chronic and non-healing wounds are marked by persistent inflammation, affecting more than six per cent of the global population.
A Concept Analysis of Pressure Ulcer Care Integrating Theory of Human Caring - PubMed
Abstract by Sumarno Adi (Indonesia - Scand J Caring Sci.).
The Scoop on Primary Intention Wound Healing (and Other Key Methods) - Mdpi.com
This article primarily focuses on primary intention healing, but such an article wouldn’t be complete without mentioning its sister methods. Keep reading to learn more about what these wound healing methods entail, the phases of wound healing, and the factors that influence wound healing in primaty intention wound healing.
Cervical Necrotizing Fasciitis in an Uncontrolled Diabetic Male Patient: A Multimodal Management Approach - Cureus.com
Article by Srinivasa Swamy Bandaru, Paul Thomas Chirayil, Maher M. Milhem, Rama M. Almasri and Mahra Almazrouei (United Arab Emirates).
An integrated approach, incorporating early imaging, repeated debridement, negative pressure therapy, and skin grafting, can significantly enhance patient outcomes. In this case, comprehensive management resulted in recovery within 21 days, shorter than the typical hospital stay for similar cases.
Enhancing Quality of Life in Patients with Acute Wounds: The Synergistic Effects of Negative Pressure Wound Therapy and Physiotherapy - Mdpi.com
Article by Cristina-Teodora Stanciu, Marcel Mihai Berceanu Vaduva, Daniel Laurentiu Pop and Dinu Vermesan (Timisoara, Romania - Biomedicines).
Combining NPWT with physiotherapy enhances functional recovery, reduces pain and anxiety, and improves quality of life. These findings support a multidisciplinary approach in acute wound management.
How Nursing Interventions in Community Care May Improve Nutritional Support in the Prevention and Treatment of Pressure Injuries - Woundsource.com
Article by Kirra Fedyszyn.
Malnutrition is a key risk factor in the development and delayed healing of pressure injuries, as it impairs immune function, decreases muscle strength, and reduces tissue tolerance to pressure.
Global Periods in 2025 - Woundsource.com
In this video interview, Dr. Vilayvanh Saysoukha explains what healthcare providers need to know about global periods as they relate to wound care and where to find more information.
Management of hypertensive leg ulcers: A French national survey - PubMed
Abstract by Y Zerdani, H Nguyen-Chi, J-B Monfort, P Senet et al. (France - Ann Dermatol Venereol.).
Understanding recurrent pressure injuries: A scoping review of current research and risk factors - Sciencedirect.com
Article by Li Du, Ning Wang, Juhong Pei, Yanxia Jiao et al. (China - Journal of Tissue Viability).
The incidence of recurrent pressure injuries varies widely, and specific definitions and standardised staging criteria must be further determined to improve clinical judgment and reporting accuracy. The risk factors for recurrent pressure injuries involve many aspects. Some studies have described local flaps and overall recurrence risk factors separately, and further verification is needed to determine whether there is a difference between the two.
Closed Incisional Negative Pressure Wound Therapy is Cost-Effective at Reducing Superficial Surgical Site Infections - Liepertpub.com
Abstract by Lauren T Kerivan, Katherine A Vilain, Terra M Hill and Christopher A Guidry (Kansas City, USA - Surg Infect (Larchmt)).
Immune cells ‘bandage’ wounds with bacteria-trapping goo - Nature.com
Article by Miryam Naddaf (London, UK).
Cells called neutrophils form gooey rings around sites where skin is punctured, study in mice shows.
Wound Care. A guide to practice for healthcare professionals - Ausmed.com.au
The guiding principles of wound care have always been focused around defining the wound, identifying any associated factors that may influence the healing process, then selecting the appropriate wound dressing or treatment device to meet the aim and aid the healing process.
The Effects of Encapsulating Bioactive Irish Honey into Pluronic-Based Thermoresponsive Hydrogels and Potential Application in Soft Tissue Regeneration - Mdpi.com
Article by Daniel P. Fitzpatrick, Emma Browne, Carmel Kealey, Damien Brady et al. (Ireland - Gels).
The manual incorporation of honey, irrespective of quality type, presented the amelioration of Pluronic’s capacity to undergo sol–gel transitions, as investigated by parallel plate rheology.
MS&E and surgery researchers team up to enhance wound healing - Wisc.edu
Article by Jason Daley.
Chronic wounds – wounds that haven’t started to heal after several weeks of treatment – affect over 6.5 million people in the U.S., are a threat to patients’ health and quality of life, and have enormous economic costs of more than $25 billion annually. Low-cost, effective, safe, and painless approaches that can accelerate wound healing are desperately needed. With a new four-year, $1.89 million grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases, researchers in the Department of Surgery and the Department of Materials Science & Engineering at the University of Wisconsin-Madison will be testing a cutting-edge technology that may fill this gap.
Novel Study Demonstrates Important Role of Microbes in Wound Healing - Biospace.com
A study led by MicroGenDX’s Caleb Phillips, Ph.D., has developed a predictive model for wound healing based on patient factors and wound microbiome composition. Conducted in collaboration with Texas Tech University and MicroGenDX, the study paves the way for a more personalized approach to wound care by identifying microbial species associated with delayed healing.
Journal of Wound Management – November Issue out now
The November 2024 edition of the Journal of Wound Management features eight insightful articles exploring advancements in wound care from global perspectives. The November issue also includes the supplement: EWMA Document on Cold Plasma. An Emerging Technology for Clinical Use in Wound Healing.
The Importance of Adequate Debridement - Generalsurgerynews.com
Article by Jarrod P. Kaufman (USA).
Debridement is a time-honored method that still has immense value for patients with acute and chronic wounds. When performed correctly and with appropriate frequency, debridement clearly leads to increased healing rates and closure in most types of wounds. Care needs to be taken, however, to clearly define the type of wound being cared for to ensure that the appropriate adjunctive methods are used in special wounds like venous ulcers or pyoderma gangrenosum.
Systematics, diagnosis and treatment of wound infections in chronic wounds: A position paper from WundDACH - PubMed
Abstract by Joachim Dissemond, Julian-Dario Rembe, Bernd Assenheimer, Marjam Barysch-Bonderer et al. (Germany, Switzerland, Ireland, Austria - J Dtsch Dermatol Ges.).
Biofilm Dispersal and Wound Infection Clearance With Preclinical Debridement Agents - Wiley.com
Article by Rebecca Elizabeth Schneider, Jason Valentino Hamdan and Kendra Pauline Rumbaugh (Lubbock, USA - International Wound Journal).
The authors found that sharp debridement followed by multiple glycoside hydrolase treatments enhanced biofilm dispersal. Furthermore, a single dose of glycoside hydrolase in combination with debridement decreased infection load in acute wounds.
Editorial for the Special Issue “Cutaneous Biology, Molecular Dermatology and Dermatopathology” - Mdpi.com
Article by Bijan Safai (USA - IJMS).
This Special Issue delves into the latest research within cutaneous biology, molecular dermatology, and dermatopathology, shedding light on molecular advancements that have recently garnered significant interest and promise substantial development.
Zinc sulfate gel reshapes the wound microenvironment to promote full-thickness wound healing in mice - Nih.gov
Article by Ying Zhang, Xuebo Wei, Yun Xu, Weidong Xia, ChaoYu Zheng et al. (China - PMC PubMed Central).
The authors demonstrated the efficacy of zinc sulfate gel in wound healing in a mouse model of full-thickness skin excision, spared the anti-inflammatory and antioxidant capabilities of zinc ions.
Nanomanaging Chronic Wounds with Targeted Exosome Therapeutics - Mdpi.com
Article by Anita Yadav, Anu Sharma, Mohini Moulick and Subhadip Ghatak (Pittsburgh, USA - Pharmaceutics).
Engineered exosomes have been shown to possess stability and effectiveness in promoting wound healing compared to their unmodified counterparts.
Update on Wound Care: Epidermal Grafting - Hmpgloballearningnetworki.com
Article by Robert S. Kirsner, Brent Bernstein, Animesh Bhatia, John Lantis et al. (USA - Dermatologist).
This article provides an overview of epidermal grafting and its potential roles in wound care and closure. Cases demonstrating the successful use of epidermal skin grafts over various wound types are also included.
Foot Ulcers in Orthopedics - PubMed
Abstract by Felix Waibel and Madlaina Schöni (Zürich, Switzerland - Ther Umsch.).
Hydrogels for Wound Dressings: Applications in Burn Treatment and Chronic Wound Care - Mdpi.com
Article by Adina Alberts, Andreea Gabriela Bratu, Adelina-Gabriela Niculescu and Alexandru Mihai Grumezescu (Bucharest, Romania - J. Compos. Sci. ).
This review aims to explore recent advancements in hydrogel-based wound dressings, emphasizing the state-of-the-art technologies used for this purpose and the trend of achieving personalized therapeutic approaches.
Nanomanaging Chronic Wounds with Targeted Exosome Therapeutics - Mdpi.com
Article by Anita Yadav, Anu Sharma, Mohini Moulick and Subhadip Ghatak (Pittsburgh, USA - Pharmaceutics).
This review seeks to explore the benefits and opportunities of exosome-based therapies in chronic wounds, ensuring sustained efficacy and precise delivery despite the obstacles posed by the wound environment.
Fish Skin Acellular Dermal Matrix Combined With Negative Pressure Wound Therapy for Diabetic Foot Ulcers - Cureus.com
Article by Audrey Poh Poh Tan and Jack Kian Chng (Singapore).
Fish skin acellular dermal matrix offers a biocompatible and sustainable solution for improving wound healing in difficult-totreat diabetic foot ulcers. The addition of NPWT appears to enhance graft uptake, shorten the time to complete wound closure, and lower the risk of infections commonly associated with chronic diabetic foot wounds.
Neutrophil Heterogeneity in Wound Healing - Mdpi.com
Article by Filippo Renó, Corinna Anais Pagano, Monica Bignotto and Maurizio Sabbatini (Italy - Biomedicines).
This review highlights the complexity of neutrophil heterogeneity and its critical roles throughout the phases of wound healing.
Efficacy and safety of platelet-rich plasma as an adjunct therapy to split thickness skin graft in burn patients with granulating raw wounds: a prospective, randomized, double-blind study . study protocol - Biomedcentral.com
Article by Susmita Behera, Biswajit Mishra, Jerin Jose Cherian, Gunjan Kumar, Smita Mahapatra et al. (India - Trials).
The proposed trial will be expected to verify the efficacy and safety of platelet-rich plasma for split-thickness skin graft in deep second-degree or third-degree granulating wounds of burn patients based on the outcome of the study.
Development of Films for Wound Healing Based on Gelatin and Oil/Water Emulsions as Carriers of Bioactive Compounds - Mdpi.com
Article by Ayelen M. Sosa, Celeste Cottet, Belén E. Berin, Luis M. Martínez et al. (Argentina - Pharmaceutics).
The active films developed could provide stable support and a safe delivery system for active compounds to treat skin lesions, minimizing the risk of infection and the need to heal a wound.
Ultrasound in Wound Healing - Physio-pedia.com
Therapeutic ultrasound is utilized by physical therapists to deliver a high frequency mechanical vibration to facilitate healing at a cellular level. Therapeutic ultrasound is often used by physiotherapists to reduce pain, increase circulation and increase mobility of soft tissues. Additionally, the application of ultrasound can be helpful in the reduction of inflammation, reducing pain and the healing of injuries and wounds.
The impact of allergic contact dermatitis on the inflammatory response and repair in wound healing process - Researchgate.net
Article by Wei Zhang, Jiabao Xu, Songyan Qu and Hui Peng (Zhengzhou, China - Frontiers in Medicine).
The study demonstrates that allergic contact dermatitis (ACD) exerts a substantial impact on the inflammatory response, cellular components, and wound healing parameters in the context of skin trauma. The heightened levels of inflammatory markers, altered cellular responses, and delayed wound closure observed in ACD patients underscore the need for targeted interventions tailored to optimize wound repair in this population.
Automated pressure ulcer dimension measurements using a depth camera - PubMed
Abstract by Chih-Yun Pai, Hunter Morera, Sudeep Sarkar, Yangxin Huang et al. (Tampa, USA - J Wound Care).
Lyophilized Extract from the Larvae of the Blowfly Lucilia sericata as a New Strategy for the Management of Chronic Wounds - Mdpi.com
Article by Norman-Philipp Hoff, Falk Peer Gestmann, Theresa Maria Jansen, Sarah Janßen et al. (Germany - Biomedicines).
In 7 of the 10 patients, the application of the extract led to a marked reduction in wound slough, and improved granulation and the progression of wound healing. These effects are likely attributable to the extract’s ability to disrupt bacterial biofilm formation.
In Vitro Effects of Low-Level Laser Therapy on the Viability and Secretory Activity of Resting Macrophages - Mdpi.com
Article by Aleksandra Matuła, Amelia Lizak, Ewa Stodolak-Zych, Aneta Bac et al. (Poland - Biomedicines).
The research results indicate that the effect of low-level laser therapy on resting macrophages modulates their biological activity, and the intensity of photobiostimulation depends on the irradiation parameters, including wavelength, power, dose and method of laser beam application.
Effects of Carbon Dioxide Therapy on Skin Wound Healing - Mdpi.com
Article by José Prazeres, Ana Lima and Gesiane Ribeiro (Lisbon, Portugal - Biomedicines).
Carboxytherapy can be considered a good alternative for treating skin wounds, although further studies should be pursued to elucidate its molecular mechanisms and enhance its efficacy.
Aloe Vera a Promising Remedy for Scald Burns - Auctoresonline.org
Article by Ravi Kumar Chittoria and Shanmuga Priya R (India).
Aloe vera is particularly beneficial in burn wound management due to its affordability, minimal side effects, widespread availability, and scientifically supported therapeutic properties.
Researchers create gel that can self-heal like human skin - Sciencedaily.com
Until now, artificial gels have either managed to replicate high stiffness or natural skin's self-healing properties, but not both. Now, a team of researchers has developed a hydrogel with a unique structure that overcomes earlier limitations, opening the door to applications such as drug delivery, wound healing, soft robotics sensors and artificial skin.
Is Nanofat the Long-Awaited Treatment for Hypertensive Ischemic Leg Ulcers? - Hmpgloballearningnetwork.com
Article by Vivien Moris, Mélodie Terrasa, Eleonor Goubeau, Leslie Ann See et al. (Dijon, France - Wounds).
The authors' study results underscore nanofat grafting as a superior alternative to traditional skin grafting for Martorell hypertensive ischemic leg ulcer, offering advantages in terms of healing time, pain management, and patient quality of life. Further research is needed to confirm these findings and assess the use of nanofat in the management of other chronic wounds.
Use of Supplemented Medical-Grade Honey to Treat Traumatic Skin Injuries in Geriatric Patients in a Home-Care Setting - Cureus.com
Article by Georgios E. Papanikolaou, Pieter Kegels, Georgios Gousios, Filip Kegels et al. (Greece, The Netherlands).
Supplemented medical-grade honey-based products present high clinical efficacy for the treatment of traumatic skin injuries in older adults in a home-care setting, while demonstrating a safe and easy-to-use profile. Therefore, they can be proposed as an alternative or complementary therapeutic approach to conventional TSI therapies.
Production of Aloe vera Phytoplacenta Extract and Potential Applications in Skincare - Mdpi.com
Article by Seung Min Jung, Hye-In Kim, Soo-Yun Kim, Sung Joo Jang et al. (Rep. of Korea - Life).
The authors' comprehensive findings underscore aloe vera phytoplacenta extract's potential in enhancing skin healing, regulating temperature, and modulating cellular processes.
Outcomes of Dermal Regeneration Template and Split-Thickness Skin Grafts in Lower Extremity Wound Closure: An 8-Year Retrospective Analysis - Hmpgloballearningnetwork.com
Article by Rachel N. Rohrich, Karen R. Li, Christian X. Lava, Sami Alahmadi et al. (Washington, USA - Wounds).
Dermal regeneration template plays a key role as a temporizing measure to significantly enhance split-thickness skin grafts take and promote ambulation in patients with chronic wounds but does not decrease the need for future major limb amputation.
Infection in Patients With Burn Injury: Sources, Pathogens, Sensitivity, and Role of Empirical Antibiotics Therapy - Hmpgloballearningnetwork.com
Article by Olayinka Adebanji Olawoye, Chinsunum Peace Isamah, Samuel Adesina Ademola, Afieharo Igbibia Michael et al. (Nigeria - Wounds).
The results of this study indicate that the source of infection determines the most likely organism and its sensitivity profile.
Nanoparticle-Enhanced Collagen Hydrogels for Chronic Wound Management - Mdpi.com
Article by Alexandra Cătălina Bîrcă, Mihai Alexandru Minculescu, Adelina-Gabriela Niculescu, Ariana Hudiță et al. (Bucharest, Romania - JFB).
The authors' results underscore the potential of nanoparticle-based collagen hydrogels as innovative therapeutic tools for managing chronic wounds.
A prospective single center non randomized clinical trial of autologous skin cells with platelet rich plasma for diabetic ulcer and trauma injuries patients - Nature.com
Article by Nur Hakimin Bin Md Noorpi, Mohd Yazid Bin Bajuri, Norliyana Binti Mazli, Ruszymah Binti Hj Idrus et al. (Kuala Lumpur, Malaysia - Scientific Reports).
The ‘skin cell drop’ approach appears safe and effective for treating diabetic ulcers and trauma wounds, with significant reductions in ulcer size.
Creation of a National Chronic Wound Registry-Challenges and Opportunities - PubMed
Abstract by Priya Bishnoi, Zifei Wang, Zhiwen Joseph Lo, Enming Yong et al. (Singapore - Int Wound J.)
Inflammation: a matter of immune cell life and death - Nature.com
Article by Elizabeth C. Bender, Halah S. Tareq and Laura J. Suggs (Austin, USA - npj Biomedical Innovations).
The authors propose that there exists a spectrum of cell living, aging, dying, and death states that have differential effects on inflammatory disease.
The use of stem cells in burns treatment - Umk.pl
Article by Monika Brzozowska, Wiktoria Wardal, Natalia Furlepa, Robert Rzenno et al. (Poland - Journal of Education, Health and Sport).
The mechanisms of action of stem cells appears to be promising in the context of treating burn wounds, but in order for them to fully replace current treatments, a deeper understanding of the complex biological mechanisms and further studies are needed to evaluate the efficacy and safety of different types of stem cells and to identify the most suitable ones.
Curcumin-Functionalized Electrospun Nanofibrous Membranes with Antimicrobial Activity for Wound Healing - Mdpi.com
Article by Neraida Petrai, Konstantinos Loukelis and Maria Chatzinikolaidou (Heraklion, Greece - Nanomaterials).
The authors' findings highlight the potential of electrosprayed curcumin as an effective strategy for bioactive wound dressings.
Wound healing and pain evaluation following diode laser surgery vs. conventional scalpel surgery in the surgical treatment of oral leukoplakia: a randomized controlled trial - Frontiersin.org
Article by Mariana de Pauli Paglioni, Caique Mariano Pedroso, Isabel Schausltz Pereira Faustino, Pablo Agustin Vargas (Brazil - Front. Oral. Health).
There was no significant difference between the diode laser and scalpel treatment arms regarding post operative pain scores. Diode lasers represent better healing at the first week post treatment, but with no differences over time. These findings support the use of either modality as viable management options for oral leukoplakia.
Putting a spotlight on palliative wound care - Cambridgemedia.com.au
Article by Georgina Gethin (Galway, Ireland - Journal of Wound Management).
In this month’s issue of Journal of Wound Management the latest EWMA document is presented, focused on palliative wound care with recommendations for the management of major wound related symptoms including pain, odour, itch, bleeding and exudate, in addition to care of the peri-wound area and nutrition.
Diagnosing Pyoderma Gangrenosum - Woundsource.com
Pyoderma gangrenosum can be a challenging diagnosis for providers to reach. In this video interview, Windy Cole, discusses how to rule out other diagnoses in order to arrive at a diagnosis of PG.
The CEAP Classification: What You Should Know - Woundsource.com
In this blog, learn how the CEAP classification system is defined and how it can be used by clinicians to identify patients at risk for venous leg ulcer (VLU) formation and better define the state of existing VLUs.
Current State and Future Trends of Research on Pressure Injuries in Nursing Homes: Network Analysis and Topic Modeling - Jwmr.org
Abstract by Sung Ok Chang and Ye-Na Lee (Seoul, Korea - J Wound Manag Res.).
3D Bioprinting of Double-Layer Conductive Skin for Wound Healing - PubMed
Abstract by Yuhan Wang, Chen Gao, Shengnan Cheng, Yuxuan Li et al. (China - Adv Healthc Mater.).
Enhancing Perioperative Care: Implementing the Scott Triggers Tool to Prevent Hospital-Acquired Pressure Injuries in Vascular Surgery Patients - PubMed
Abstract by Ruth Mosher (AORN J.).