Photocrosslinked gelatin hydrogel improves wound healing and skin flap survival by the sustained release of basic fibroblast growth factor - Nature.com
Article by Toshihiro Kushibiki, Yoshine Mayumi, Eiko Nakayama, Ryuichi Azuma, Kenichiro Ojima, Akio Horiguchi and Miya Ishihara (Saitama, Japan - Scientific Reports).
The photocrosslinking gelatin hydrogel designed in this study is a potential candidate to enhance wound healing and better skin flap survival.
Using of Amniotic Membrane Derivatives for the Treatment of Chronic Wounds - Mdpi.com
Article by Iveta Schmiedova, Alena Dembickaja, Ludmila Kiselakova, Beata Nowakova and Petr Slama (Czech Republic - Membranes).
Based on authors' results the use of the amniotic membrane for chronic wounds can be considered highly effective.
A smart bandage is the future of fighting infections - Innovationorgins.com
Technion scientists develop self-healing, antibacterial polymer as safer alternative to traditional post-surgical sutures. The smart bandage can dispense antibiotic, monitor wound-healing biomarkers and report important data directly to doctors.
Nutritional Support - Woundsource.com
Article by Nancy Munoz.
Nutritional deficiency is the term used when the reserves of nutrients stored in the body are insufficient to support healthy cellular function. A wound requires nutrients to be redirected from their normal functions to use in the various stages of the healing process. However, when the individual is malnourished, any trauma may prove disastrous as they lack the reserves to respond to the metabolic demands of the wound.
Lower Extremity Wounds: Differential Assessment and Management - Woundsource.com
Article by Holly Hovan.
Lower extremity wounds can often be refractory or slow healing. These wounds require an interprofessional approach and effective, evidence-based management for optimal healing and prevention of recurrence.
Management of complex surgical wounds of the back: identifying an evidence-based approach - PubMed
Abstract by Elizabeth G Zolper, Meher A Saleem, Kevin G Kim, Mark D Mishu, Sarah R Sher, Christopher E Attinger, Kenneth L Fan and Karen K Evans (Washington, USA - Arch Plast Surg.).
Novel imaging methods reveal positive impact of topical negative pressure application on tissue perfusion in an in vivo skin model - PubMed
Abstract by Wibke Müller-Seubert, Sascha Roth, Theresa Hauck, Andreas Arkudas, Raymund E Horch and Ingo Ludolph (Erlangen, Germany - Int Wound J.).
In vitro Antioxidant and in vivo Wound Healing Activities of the 80% Methanol Extract and Solvent Fractions of Seeds of Brassica carinata A. Braun (Brassicaceae) in Mice - Dovepress.com
Article by Belete Kassa Alemu, Kefyalew Ayalew Getahun and Wubayehu Kahaliw (Ethiopia - Journal of Experimental Pharmacology).
The study demonstrated that the 80% methanol extract and solvent fractions of the seeds of B.carinata possess potential wound healing and anti-oxidant effects, supporting the traditional use of the plant for wound management.
Topical Gynura procumbens as a Novel Therapeutic Improves Wound Healing in Diabetic Mice - Mdpi.com
Article by Nutda Sutthammikorn, Volaluck Supajatura, Hainan Yue, Miho Takahashi, Sunee Chansakaow, Nobuhiro Nakano, Pu Song, Takasuke Ogawa, Shigaku Ikeda, Ko Okumura, Hideoki Ogawa and François Niyonsaba (Thailand, Japan, China - Plants).
The findings that G. procumbens accelerates wound healing and activates cells involved in the wound healing process suggest that G. procumbens might be an effective alternative therapeutic option for nonhealing diabetic wounds.
Chronic Venous Leg Ulcer in Klinefelter Syndrome Treated with Platelet-Rich Fibrin: A Case Report - Dovepress.com
Article by Eva Krishna Sutedja, Retno Hesty Maharani, Unwati Sugiri and Pati Aji Achdiat (Bandung, Indonesia - International Medical Case Reports Journal).
Recurrent VLUs are possibly associated with chromosomal abnormalities such as KS. Here, we report on the treatment of KS-associated VLU using PRF with a good therapeutic response.
Non-surgical Management of Complex Refractory Pyoderma Gangrenosum With Negative Pressure Wound Therapy With Instillation - PubMed
Abstract by Frank G Lee, Ethan Song, Sean J Wallace, Thomas J Shaughnessy, Mamtha Raj, Robert Teixeira, Marshall G Miles and Randolph Wojcik Jr (USA - Cureus).
An Overview of Cellulose Derivatives-Based Dressings for Wound-Healing Management - Mdpi.com
Article by Elena-Emilia Tudoroiu, Cristina-Elena Dinu-Pîrvu, Mădălina Georgiana Albu Kaya, Lăcrămioara Popa, Valentina Anuța, Răzvan Mihai Prisada and Mihaela Violeta Ghica (Bucharest, Romania - Pharmaceuticals).
This review presents an extensive overview of recent research regarding promising cellulose derivatives-based materials for the development of multiple biomedical and pharmaceutical applications, such as wound dressings, drug delivery devices, and tissue engineering.
Facile preparation of polysaccharides-based adhesive hydrogel with antibacterial and antioxidant properties for promoting wound healing - PubMed
Abstract by Qingcong Wei, Kunyu Chen, Xiaoyu Zhang, Guanglei Ma, Weiwei Zhang and Zhiguo Hu (Xinxiang, China - Colloids Surf B Biointerfaces).
Resveratrol-Induced Signal Transduction in Wound Healing - Mdpi.com
Article by Anna-Lisa Pignet, Marlies Schellnegger, Andrzej Hecker, Michael Kohlhauser, Petra Kotzbeck and Lars-Peter Kamolz (Graz, Austria - IJMS).
This review highlights the resveratrol-induced molecular pathways with particular focus on the most relevant variables in wound healing, namely inflammation, oxidative stress, autophagy, collagen proliferation and angiogenesis.
Evaluation of Wound Healing Potential of Novel Hydrogel Based on Ocimum basilicum and Trifolium pratense Extracts - Mdpi.com
Article by Ina Andreea Antonescu (Mintaș), Angela Antonescu, Florina Miere (Groza), Luminița Fritea, Alin Cristian Teușdea, Laura Vicaș, Simona Ioana Vicaș, Ilarie Brihan, Maria Domuța, Mihaela Zdrinca, Marcel Zdrinca and Simona Cavalu (Oradea, Romania - Processes).
The topical use of the novel gel formulation containing EOT is a successful therapeutic alternative in the treatment of dermal diseases.
Arginine: What You Need to Know for Pressure Injury Healing - Lww.com
Article by Andy S. Chu and Barbara Delmore (New York, USA - Advances in Skin & Wound Care).
This article provides necessary background on this conditionally indispensable amino acid, its metabolism, and its role in acute and chronic wound healing to assist providers in understanding the recommendation for arginine supplementation.
Novel temperature responsive films impregnated with silver nano particles (Ag-NPs) as potential dressings for wounds - PubMed
Abstract by Joginder Singh Paneysar, Stephen Barton, Premlata Ambre and Evans Coutinho (India, UK - J Pharm Sci.).
Wound Care and Healing for Neonates - Dermatologytimes.com
Article by Linda Stocum. A study published in the Advances in Skin & Wound Care Journal examined wound care information to help educate about care for the specific physiology of newborns.
Pediatric Patients - Woundsource.com
There is often an association when caring for pediatric wounds that they can heal rapidly and that patients have remarkable resilience. This perpetuating thought has resulted in a lack of focus on wound care knowledge in pediatrics. In reality, these patients are among the most vulnerable populations, generally have skin that is more fragile than adult skin, and many of their systems are immature, which can complicate wound care.
A Review of the Skin Failure Concept - Woundsource.com
Article by Jeffrey M. Levine. Like all other organs, skin can fail; however, experts continue to grapple with definitions, causative factors, and manifestations. By defining contributing factors that apply to other organ systems, providers establish skin failure as an entity and thus are able to recognize and address it in practice.
A Peptide/MicroRNA-31 Nanomedicine within an Electrospun Biomaterial Designed to Regenerate Wounds In Vivo - PubMed
Abstract by Mulholland Ej, McErlean Em, Dunne N and McCarthy Ho (United Kingdom, Ireland - Acta Biomater.).
pdf (980 kB)!
Nursing knowledge on skin ulcer healing: a living scoping review protocol - Lww.com
Article by Joao Gomes, Paulino Sousa, Filipe Pereira, Carmen Queiros, Hugo Neves, Catarina Silva, Abel Paiva e Silva, Paulo Parente, Paula Sousa, Alice Brito, Antonia Paiva e Silva, Ernesto Jorge Morais, Alexandrina Cardoso, Ines Cruz, Natalia Machado, Fernando Oliveira, Fernanda Bastos, Paula Prata and Carlos Sequeira (Portugal, JBI).
This review aims to continuously map the nursing knowledge on skin ulcer healing in any context of care.
Pattern of Wound Healing In Burn Patients Nursed On Air Fluidized Bed System: A Study of37 Cases - Ijhcr.com
Article by Poonam Gupta, Shammi Purwar and Shesh Kumar (Saifai-Etawah, India - International Journal of Health and Clinical Research).
The wound healing in burn patients nursed on air fluidized bed is faster than conventionalsetting.It alsoreduces psychological trauma like post traumatic stress disorder (PTSD)as well as overall mortality.
Virtual Reality-Based Analysis of Pressure Ulcer Care Information Related to Medical Equipment for the Prevention of Pressure Ulcer Skin Foam Dressings in the Elderly - PubMed
Abstract by Na Zhao, Zhanhong Tian, Yang Li, Haihua Yu and Yu Yang (China - J Healthc Eng.).
Fabricating scalable, personalized wound dressings with customizable drug loadings via 3D printing - PubMed
Abstract by Jia Heng Teoh, Sook Muay Tay, Jerry Fuh and Chi-Hwa Wang (Singapore - J Control Release).
Roles of Oxidative Stress and Raftlin in Wound Healing Under Negative-Pressure Wound Therapy - Dovepress.com
Article by Xingan Qiu, Yifan Wu, Dong Zhang, Hao Zhang, Aixi Yu and Zonghuan Li (Wuhan, China - Clinical, Cosmetic and Investigational Dermatology).
NPWT may promote wound healing by upregulating Raftlin and inhibiting oxidative stress levels.
Biocompatibility evaluation for the developed hydrogel wound dressing - ISO-10993-11 standards - InVitro and InVivo study - PubMed
Abstract by Thanusha Av and Veena Koul (New Delhi, India - Biomed Phys Eng Express).
VEGF-A, PDGF-BB and HB-EGF engineered for promiscuous super affinity to the extracellular matrix improve wound healing in a model of type 1 diabetes - Nature.com
Article by Michael J. V. White, Priscilla S. Briquez, David A. V. White and Jeffrey A. Hubbell (USA - npj Regenerative Medicine).
The authors' results suggest that the triple therapy of VEGF-PlGF-2123–144, PDGF-BB-PlGF-2123–144, and HB-EGF-PlGF-2123–144 may be an effective therapy for chronic non-healing wounds in that occur as a complication of diabetes.
Experimental study of fat derived pellets promoting wound healing in rats - Tandofonline.com
Article by Li Zeng, Shaolong Zhou, Chen Chen, Lin-hua Zhou, Xiujiang Shi,Zongjian Wu and Sheng-Kang Luo (China - Bioengineered).
The cytotherapeutic effect of fat derived pellets makes it a promising product for wound healing in clinics.
Wound healing activities of polyurethane modified chitosan nanofibers loaded with different concentrations of linezolid in an experimental model of diabetes - Sciencedirect.com
Abstract by Mahmoud H.Teaima, Mohamed K. Elasaly, Samia A. Omar, Mohamed A. El-Nabarawi and Kamel R.Shoueir (Egypt, France - Journal of Drug Delivery Science and Technology).
Anti-Aging β-Klotho Gene-Activated Scaffold Promotes Rejuvenative Wound Healing Response in Human Adipose-Derived Stem Cells - Mdpi.com
Article by Ashang L. Laiva, Fergal J. O’Brien and Michael B. Keogh (Bahrain, Ireland - Pharmaceuticals).
The authors determined that the β-Klotho gene-activated scaffold possesses tremendous potential for wound healing and could advance stem cell-based therapy for rejuvenative healing applications.
Growth factors for treating chronic venous leg ulcers: A systematic review and meta-analysis - Wiley.com
Abstract by Yung Lee, Michael H. Lee, Steven A. Phillips and Michael C. Stacey (Wound Repair and Regeneration).
Pressure Injury Prevalence in Acute Care Hospitals With Unit-Specific Analysis: Results From the International Pressure Ulcer Prevalence (IPUP) Survey Database - PubMed
Abstract by Catherine A VanGilder, Jill Cox, Laura E Edsberg and Kimberly Koloms (USA - J Wound Ostomy Continence Nurs.).
Impact of Complex Wounds on Health-Related Quality of Life: A Descriptive Study - PubMed
Abstract by Catherine R Ratliff and Virginia Rovnyak (Charlottesville, USA - J Wound Ostomy Continence Nurs.).
Characterization and Topical Study of Aloe Vera Hydrogel on Wound-Healing Process - Mdpi.com
Article by Karen Zulema Meza-Valle, Rosa Alicia Alicia Saucedo-Acuña, Karla Lizzette Lizzette Tovar-Carrillo, Juan Carlos Carlos Cuevas-González, Erasto Armando Armando Zaragoza-Contreras and Juana Melgoza-Luevano (Mexico - Polymers).
The results indicated that the Aloe vera hydrogel, prepared with propanediol and TEA, together with its superficial characteristics, improve its rapid penetration without drying out the treated tissue. This produced a positive influence on inflammation, angiogenesis, and wound contraction, reducing 29% the total healing time, reaching the total closure of the wound in 15 days.
Effectiveness of low-level laser therapy compared with other conventional therapies on wound healing and pain reduction in patients with median sternotomy: a systematic review protocol - Lww.com
Article by Mahendiran Murugan, Raja Regan and Ashokan Arumugam (India, United Arab Emirates - JBI Evidence Synthesis).
The outcomes of this review will be of interest to health care professionals (eg, surgeons, physiotherapists, nurses), researchers, and patients regarding the safe use of LLLT in combination with, or as an alternative to, other interventions for augmenting wound healing and reducing pain following median sternotomy.
Efficacy and safety of CO2 laser in the treatment of chronic wounds: A Retrospective Matched Cohort Trial - Wiley.com
Abstract by Haonan Guan, Di Zhang, Xian Ma, Yechen Lu, Jiaoyun Dong, Yiwen Niu, Yingkai Liu, Shuliang Lu, Jiping Xu and Jiajun Tang (Lasers in Sugery and Medicine).
Preparation and Characterization of Curcumin Nanoemulgel Utilizing Ultrasonication Technique for Wound Healing: In Vitro, Ex Vivo, and In Vivo Evaluation - Mdpi.com
Article by Mohammed S. Algahtani, Mohammad Zaki Ahmad, Ihab Hamed Nourein, Hassan A. Albarqi, Hamad S. Alyami, Mohammad H. Alyami, Abdulsalam A. Alqahtani, Ali Alasiri, Thamer S. Algahtani, Abdul Aleem Mohammed and Javed Ahmad (Najran, Saudi Arabia - Gels).
The in vivo wound healing efficacy study and histological examination of healed tissue specimen further signify the role of the nanomedicine-based approach to improve the biopharmaceutical attributes of curcumin.
Consistent practices in pressure ulcer prevention based on international care guidelines: A cross-sectional study - PubMed
Abstract by Elina Haavisto, Minna Stolt, Pauli Puukka, Teija Korhonen and Emilia Kielo-Viljamaa (Finland - Int Wound J.).
Effect of Postoperative Compression Therapy on the Success of Liposuction in Patients with Advanced Lower Limb Lymphedema - PubMed
Abstract by Shuhei Yoshida, Isao Koshima, Hirofumi Imai, Solji Roh, Toshiro Mese, Toshio Uchiki, Ayano Sasaki and Shogo Nagamatsu (Hiroshima, Japan - J Clin Med.).
Overcoming the Challenge of Support Surface Selection: Utilization of Standards - PubMed
Abstract by Kristen Thurman, Michelle Deppisch, Susan S Morello, Rachel Moseley, Stephanie Slayton, Cynthia Sylvia and Jackie Todd (USA - Adv Skin Wound Care).
Fistula Focus: Practical Application Tips for Managing Fistulas - Woundsource.com
Article by Mary Anne R. Obst. A fistula is a connection between two organs that are not normally connected, such as the stomach and the skin. Fistulas develop in various conditions and for a multitude of reasons, such as malignancy, Crohn’s disease, colitis, and others. Many times, fistulas occur after a surgical procedure.
Integration of Choline Chloride-Based Natural Deep Eutectic Solvents and Macroporous Resin for Green Production of Enriched Oil Palm Flavonoids as Natural Wound Healing Agents - Mdpi.com
Article by Mohamad Shazeli Che Zain, Jen Xen Yeoh, Soo Yee Lee, Adlin Afzan and Khozirah Shaari (Selangor, Malaysia - Antioxidants).
Results of the study showed that natural deep eutectic solvents (NaDES) could be a promising eco-friendly green solvent to extract bioactive oil palm (Elaeis guineensis Jacq.) leaves flavonoids that have great potential for applications as wound healing agents.
Use of Oxidized Regenerated Cellulose/Collagen Matrix in Chronic Diabetic Foot Ulcers: A Systematic Review - Lww.com
Article by Gisele Chicone, Viviane Fernandes de Carvalho and Andre´ Oliveira Paggiaro (Sao Paulo, Brazil - Advances in Skin & Wound Care).
Because of several methodology flaws in the reviewed studies, these results suggest that there is currently no research evidence to suggest that the use of oxidized regenerated cellulose/collagen matrix (ORC+C) improves wound healing rates of DFUs.
Design, preparation and in vitro characterization of biomimetic and bioactive chitosan/polyethylene oxide based nanofibers as wound dressings - PubMed
Abstract by Oana Maria Ionescu, Andreea-Teodora Iacob, Arn Mignon, Sandra Van Vlierberghe, Mihaela Baican, Maricel Danu, Constanța Ibănescu, Natalia Simionescu and Lenuța Profire (Romania, Belgium - Int J Biol Macromol.).
Evaluation of the Healing Effect of Ointments Based on Bee Products on Cutaneous Lesions in Wistar Rats - Mdpi.com
Article by Calin Vasile Andritoiu, Cristina Lungu, Maricel Danu, Bianca Ivanescu, Corina Elena Andriescu, Laurian Vlase, Corneliu Havarneanu, Camelia Elena Iurciuc (Tincu) and Marcel Popa (Romania, Pharmaceuticals).
All ointments had beneficial effects on wound contraction and the re-epithelialization period, but the most significant result, both macroscopically and especially in terms of histological architecture, was presented by the ointment that contains all three apitherapy products, due to their synergistic effect.
Chlorhexidine Coated Polyglactin Sutures In Prevention Of Surgical Site Infection - Pharmascope.org
Article by Shivangi Gaur, Subhashini R., Madhulaxmi M. and Abdul Wahab P. U. (India - International Journal of Research in Pharmaceutical Sciences).
Concerning the total number of oral pathogens, that adhered to suture material, no reduction was demonstrated for Chlorhexidine coated sutures. The use of chlorhexidine-coated suture material offers no advantage in intraoral surgery.
Pressure ulcers microbiota dynamics and wound evolution - PubMed
Abstract by Catherine Dunyach-Remy, Florian Salipante, Jean-Philippe Lavigne, Maxime Brunaud, Christophe Demattei, Alex Yahiaoui-Martinez, Sophie Bastide, Claire Palayer, Albert Sotto and Anthony Gélis (France - Sci Rep.).
Synthesis and characterization of a novel pH-responsive drug-releasing nanocomposite hydrogel for skin cancer therapy and wound healing - Rsc.org
Abstract by Andrea Gonsalves, Pranjali Tambe, Duong Le, Dheeraj Thakore, Aniket S. Wadajkar, Jian Yang, Kytai T. Nguyen and Jyothi U. Menon (USA - Journal of Materials Chemistry B).
Ion channel mechanosensor plays a key role in regulating the speed of skin wound healing - News-medical.net
PIEZO1, an ion channel mechanosensor found within cells, has been revealed to play a key role in regulating the speed of skin wound healing by researchers at the University of California, Irvine (UCI).
New Perspectives on Old and New Therapies of Staphylococcal Skin Infections: The Role of Biofilm Targeting in Wound Healing - Mdpi.com
Article by Oriana Simonetti, Giulio Rizzetto, Giulia Radi, Elisa Molinelli, Oscar Cirioni, Andrea Giacometti and Annamaria Offidani (Ancona, Italy - Antibiotics).
According to the authors' review of the literature, targeting of biofilm is an important therapeutic choice in acute and chronic infected skin wounds both to overcome antibiotic resistance and to achieve better wound healing.
Cerium oxide nanoparticle conjugation to microRNA-146a mechanism of correction for impaired diabetic wound healing - PubMed
Abstract by Lindel C Dewberry, Stephen M Niemiec, Sarah A Hilton, Amanda E Louiselle, Sushant Singh, Tamil S Sakthivel, Junyi Hu, Sudipta Seal, Kenneth W Liechty and Carlos Zgheib (USA, India - Nanomedicine).
Factors associated with pressure ulcer onset after knee replacement - PubMed
Abstract by Cristiana Forni, Nicola Cerantola, Gianfranco Ferrarelli, Luana Lombrosi, Andrea Bolzon, Emanuela Natali, Fabio D'Alessandro and Mattia Morri (Bologna, Italy - J Wound Care).
The successful use of polylactide wound dressings for chronic lower leg wounds: A retrospective analysis - Wiley.com
Article by Sebastian P. Nischwitz, Daniel Popp, David Shubitidze, Hanna Luze, Robert Zrim, Klaus Klemm, Matthias Rapp, Herbert L. Haller, Manuel Feisst and Lars-Peter Kamolz (Austria, Germany - International Wound Journal).
This study shows that Suprathel is a valuable tool in the armamentarium of a wound specialist. Not only could the authors show a positive effect on chronic wounds, they could even demonstrate a significant wound size reduction in chronic wounds of old and young, as well as diabetic wounds, with the treatment of older chronic and diabetic wounds yielding an even larger effect size.
Injectable and Antioxidative HT/QGA Hydrogel for Potential Application in Wound Healing - Mdpi.com
Article by Yikun Ren, Dan Zhang, Yuanmeng He, Rong Chang, Shen Guo, Shanshan Ma, Minghao Yao and Fangxia Guan (Zhengzhou, China - Gels).
This hydrogel exhibited excellent injectability, favorable antioxidant activity, and good biocompatibility. Moreover, the authors evaluated the therapeutic effect of HT/QGA hydrogel in a full-thickness skin injury model. These results suggested that HT/QGA hydrogel may offer a great potential application in wound healing.
A Case for Hypochlorous Acid Solution as a Replacement for NSS in Wound Hygiene: A Review - Lermagazine.com
Article by James McGuire. Given its lack of efficaciousness in decreasing bioburden, normal sterile saline may not be the best solution for this important task.
IL-36Ra discovery may help heal skin wounds from ischemia reperfusion - Drugtargetreview.com
The absence of interleukin-36 receptor antagonist (IL-36Ra) significantly slowed down wound healing in ischemia-reperfusion injuries in mice.
Enhanced wound healing properties of guar gum/curcumin-stabilized silver nanoparticle hydrogels - Nature.com
Article by Sakkarin Bhubhanil, Chanon Talodthaisong, Mattaka Khongkow, Katawut Namdee, Prapimpun Wongchitrat, Werayut Yingmema, James A. Hutchison, Sarawut Lapmanee and Sirinan Kulchat (Thailand, Australia - Scientific Reports).
Histopathology indicates that the hydrogel composite enhances transition from the inflammation to proliferation stage of healing, promoting the formation of fibroblasts and new blood vessels, while target gene expression studies confirm that the accelerated tissue remodeling occurs along the normal pathways. As such these hydrogel composites show great promise as wound dressing materials with high antibacterial capacity.
Outpatient wound clinics during COVID-19 maintained quality but served fewer patients - Jamda.com
Article by Sang Kyu Cho, Soeren Mattke, Mary Sheridan and William Ennis (USA - JAMDA).
Despite COVID-19 related disruptions, the authors' results suggest that wound care clinics maintained standards of care and outcomes for patients who sought care. This positive result should not detract from the problem that the number of new wounds seen at the clinics dropped sharply.
Development of nanobiomaterial for wound healing based on silver nanoparticles loaded on chitosan hydrogel - Springer.com
Abstract by S. Bharathi, B. Ramesh, S. Kumaran, M. Radhakrishnan, D. Saravanan, P. Saravanan, S. R. Pugazhvendan and M. S. Nalinasundari (Biotech).
Effect on healing rates of wounds treated with direct cold atmospheric plasma: a case series - Magonlinelibrary.com
Abstract by Jennifer Ernst, Murat Tanyeli, Thomas Borchardt, Moses Ojugo, Andreas Helmke, Wolfgang Viöl, Arndt F Schilling and Gunther Felmerer (Journal of Wound Care).
Wound Care, Then and Now: A Brief History of the Evolution of Wound Care - Woundsource.com
Article by Emily Greenstein. Wound care has evolved from treatments based on superstition to systematic, evidence-based care. The history of wound healing dates back to 2000 BCE.
Skin injuries associated with severe life-threatening situations: A new conceptual framework - PubMed
Abstract by Francisco Pedro García-Fernández, J Javier Soldevilla-Agreda, Manuel Rodriguez-Palma and Pedro L Pancorbo-Hidalgo (Spain - J Nurs Scholarsh.).
The global burden of decubitus ulcers from 1990 to 2019 - PubMed
Abstract by Xianghong Zhang, Na Zhu, Zhihong Li, Xiangtao Xie, Tang Liu and Guoqing Ouyang (China - Sci Rep.).
Direct Current Electrical Fields Improve Experimental Wound Healing by Activation of Cytokine Secretion and Erk1/2 Pathway Stimulation - Mdpi.com
Article by Chao Lu, Jonas Kolbenschlag, Andreas K. Nüssler, Sabrina Ehnert, Colin D. McCaig, Urška Čebron, Adrien Daigeler and Cosima Prahm (Germany, UK - Life).
The results demonstrate that exposure of human epidermal cells to direct current electric fields has positive effects on migration, proliferation, and cytokine secretion - three important steps in wound healing - and these effects may be partially mediated by activation of the Erk1/2 signaling pathway.
Cellular Mechanisms and Therapies in Wound Healing: Looking toward to Future - Researchgate.net
Article by Stefani Bacci (Florence, Italy - Biomedicines).
A deep knowledge of cellular infiltrate responses remains fundamental to the study of wound healing. In fact, there must be an awareness of the fact that the modulation of effector cells (fibroblasts or myofibroblasts) is related to other cell types deeply involved in wound healing (for example, mast cells or dendritic cells) that are present in the skin microenvironment.
Gremlin: a complex molecule regulating wound healing and fibrosis - PubMed
Abstract by Steven O'Reilly (Durham, UK - Cell Mol Life Sci.).
Hold the antibiotics: next-generation hydrogels have arrived - Biotechniques.com
Article by Storm Johnson. Scientists in Sweden have created a new class of non-antibiotic hydrogel capable of fighting multidrug-resistant (MDR) bacterial infections by enhancing the skin’s natural immune defense.
Platelet-Rich Fibrin in Combination with Local Antibiotics Optimizes Wound Healing After Deep Sternal Wound Problems and Prevents Reinfection - PubMed
Abstract by Ralf-Uwe Kuehnel, Filip Schroeter, Torsten Mueller, Roya Ostovar and Johannes M Albes (Bernau, Germany - Surg Technol Int.).
The Hemostatic and Wound Healing Effect of Chitosan Following Debridement of Chronic Ulcers - PubMed
Abstract by David H Keast and Ashrafunissa Janmohammad (London, Canada - Wounds).
Insight Into the Beneficial Role of Lactiplantibacillus plantarum Supernatant Against Bacterial Infections, Oxidative Stress, and Wound Healing in A549 Cells and BALB/c Mice - Frontiersin.org
Article by Ashish Kumar Dubey, Mansi Podia, Priyanka, Sachin Raut, Sanpreet Singh, Anil Kumar Pinnaka and Neeraj Khatri (Chandigarh, India - Front. Pharmacol.).
The authors' findings unveil a protective role of Lp2621 against bacterial infection, oxidative stress, and wound healing.
A new innovation in topical diabetic foot ulcer; hyaluronic acid platelet-rich fibrin (HAPRF) gel - a study in inflammation and angiogenesis - Balimedicaljournal.org
Article by Ronald W. Kartika, Idrus Alwi, Em Yunir, Sarwono Waspadji, Saptawati Bardosono, Suzzana Immanuel, Todung Silalahi, Saleha Sungkar, Jusuf Rachmat, Franciscus D. Suyatna and Mirta Hediyati Reksodiputro (Jakarta, Indonesia - Bali Medical Journal).
A-PRF +HA administration leads to reduce IL-6 levels, and accelerated wound healing of DFUs patients. HAPRF directly aids epithelialization and granulation index.
Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels - Hindawi.com
Article by Monica Mesa and Natalia Y. Becerra (Medellín, Colombia - International Journal of Biomaterials).
The effects of tailoring the porous, morphological, and chemical characteristics of synthetic silicas on the bioactivity of hybrid wound dressings hydrogels are explored in the first part of the review. This is followed by a commented review of the mechanisms of silica/protein and silica/polysaccharide interactions and their impact on the barrier, scaffold, and delivery matrix functions of the derived hydrogels.
Agrin-Matrix Metalloproteinase-12 axis confers a mechanically competent microenvironment in skin wound healing - Nature.com
Article by Sayan Chakraborty, Divyaleka Sampath, Melissa Ong Yu Lin, Matthew Bilton, Cheng-Kuang Huang, Mui Hoon Nai, Kizito Njah, Pierre-Alexis Goy, Cheng-Chun Wang, Ernesto Guccione, Chwee-Teck Lim and Wanjin Hong (Singapore - Nature Communications).
Agrin overhauls cytoskeletal architecture via enhancing actomyosin cables upon sensing geometric stress and force following an injury. Moreover, the authors identify Matrix Metalloproteinase-12 (MMP12) as a downstream effector of Agrin’s mechanoperception.
Efficacy of Hydromechanical Therapy in Nonhealing, Chronic Wounds as a Cost- and Clinically Effective Wound Care Modality - Hmpgloballearningnetwork.com
Article by Haley DesJardins, Sydney Char, Patrick Marasco, Yung-Chang Hsu and Lifei Guo (Burlington, USA).
The current clinical results offer a new perspective on the role of a traditional surgical modality of hydromechanical therapy in chronic wound care and on the associated opportunity of potential cost savings.
Epidemiology, Pathophysiology, and Management Strategies of Neonatal Wound Care - PubMed
Abstract by Yomna Amer, Catherine Bridges and Kalyani Marathe (USA - Neoreviews).
Association of Pressure injury with body care activities in nursing homes - PubMed
Abstract by Kinjal N Sethuraman, Surbhi Leekha, Timileyin Adediran and Mary Claire Roghmann (Baltimore, USA - Wound Repair Regen.).
VAP-PLGA Microspheres (VAP-PLGA) Promote Adipose-Derived Stem Cells (ADSCs)-Induced Wound Healing in Chronic Skin Ulcers in Mice via PI3K/Akt/HIF-1α Pathway - Tandfonline.com
Article by Wen Jiang, Jun Zhang, Xudong Zhang, Chenghong Fan and Jinlong Huang (China - Bioengineered).
VAP promoted the growth, migration, invasion and angiogenesis of ADSCs through activating PI3K/Akt/HIF-1α pathway, and VAP-PLGA enhanced the function of ADSCs in promoting wound healing in vivo, which was associated with angiogenesis, inflammation inhibition and dermal collagen synthesis.
Energy-based devices for the treatment of acne scars: 2021 international consensus recommendations - PubMed
Abstract by Fares Salameh, Peter R Shumaker, Greg J Goodman, Leah K Spring, Meghan Seago, Murad Alam, Firas Al-Niaimi, Daniel Cassuto, Henry Hl Chan, Christine Dierickx, Matthias Donelan, Gerd G Gauglitz, Merete Haedersdal, Andrew C Krakowski, Woraphong Manuskiatti, William B Norbury, Rei Ogawa, David M Ozog, Uwe Paasch, E Victor Ross, Matteo Tretti Clementoni, Jill Waibel, Ardeshir Bayat, Boncheol Leo Goo and Ofir Artzi (Israel, USA, Australia, Denmark, Italy,
China, Luxembourg, Germany, Thailand, Japan, UK, South Africa, Korea - Lasers Surg Med.).
Topical application of metformin accelerates cutaneous wound healing in streptozotocin-induced diabetic rats - PubMed
Abstract by Fatma Kubra Tombulturk, Zeynep Gizem Todurga-Seven, Onder Huseyinbas, Sibel Ozyazgan, Turgut Ulutin and Gonul Kanigur-Sultuybek (Istanbul, Turkey - Mol Biol Rep.).
Wound Healing with Electrical Stimulation Technologies: A Review - Mdpi.com
Article by Yt Jun Cheah, Muhamad Ramdzan Buyong and Mohd Heikal Mohd Yunus (Malysia - Polymers).
With the emerging of tissue engineering and regenerative medicine, the integration of electroconductive biomaterials into modern miniaturised dressing is of interest and has become possible with the advancing understanding of smart biomaterials.
Living Bacterial Hydrogels for Accelerated Infected Wound Healing - Wiley.com
Article by Zunzhen Ming, Lin Han, Meiyu Bao, Huanhuan Zhu, Sujing Qiang, Shaobo Xue and Weiwei Liu (Advanced Sciences).
Both in vitro and in vivo experiments show that hydrogel scaffold has excellent ability against harmful bacteria and anti-inflammatory capabilities, promoting infected wound closure and new tissue regeneration. This work may open up new avenues for the application of living bacteria in the clinical management of infected wounds.
Skin Type and Microbiome Determine the Speed of Wound Healing - Technologynetworks.com
Although the wound healing process in mammals and fish is remarkably similar, research on the latter is scarce. To fill this knowledge gap, a team of undergraduate students from Daegu Gyeongbuk Institute of Science and Technology, Korea, conducted a comparative study of wound healing in seven different fish species and investigated the role played by the skin bacterial community, demonstrating that fish can be an excellent model for exploring the mechanisms of wound healing.
The signaling pathways of traditional Chinese medicine in promoting diabetic wound healing - Sciencedirect.com
Abstract by Xin Zhou, Yanling Guo, Kun Yang, Peng Liu and Jun Wang (Tianjin, China - Journal of Ethnopharmacology).
3D bioprinted silk fibroin hydrogels for tissue engineering - PubMed
Abstract by Soon Hee Kim, Heesun Hong, Olatunji Ajiteru, Md Tipu Sultan, Young Jin Lee, Ji Seung Lee, Ok Joo Lee, Hanna Lee, Hae Sang Park, Kyu Young Choi, Joong Seob Lee, Hyung Woo Ju, In-Sun Hong and Chan Hum Park (Republic of Korea - Nat Protoc.).
Treatment of open wounds secondary to trauma using polyurethane foams with boric acid particles - PubMed
Abstract by Hasan Ulaş Oğur, Rana Kapukaya, Osman Çiloglu, Özgür Külahcı, Volkan Tolga Tekbaş and Abdulkerim Yörükoğlu (Turkey - Ulus Travma Acil Cerrahi Derg).
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