pdf (880 kB)!
Anti-Inflammatory, Antioxidant, and Wound-Healing Properties of Cyanobacteria from Thermal Mud of Balaruc-Les-Bains, France: A Multi-Approach Study - Mdpi.com
Article by Justine Demay, Sébastien Halary, Adeline Knittel-Obrecht, Pascal Villa, Charlotte Duval, Sahima Hamlaoui, Théotime Roussel, Claude Yéprémian, Anita Reinhardt, Cécile Bernard and Benjamin Marie (France, Biomolecules).
The authors' study shows a promising potential in further developments for Balaruc’s cyanobacteria and opens avenues of future work for applications of the active biomolecules, improvement of their production, and the resolution of their mechanism of action.
Does Hyperbaric Oxygen Improve Lower Extremity Ulcer Outcomes? - Nih.gov
Abstract by Laura Bolton (New Brunswick, USA - Wounds).
Cost Effectiveness of Fish Skin Grafts Versus Standard of Care on Wound Healing of Chronic Diabetic Foot Ulcers: A Retrospective Comparative Cohort Study - Nih.gov
Abstract by Christopher Winters, Robert S Kirsner, David J Margolis and John C Lantis (USA - Wounds).
Plastic Surgery Reconstruction of Chronic/Non-Healing Wounds - Nih.gov
Abstract by Tim Leypold, Benedikt Schäfer, Anja M Boos and Justus P Beier (Aachen, Germany - Surg Technol Int.).
Impact of a Swiss pressure ulcer prevention breakthrough collaborative - Nih.gov
Abstract by Anthony Staines, Isabelle Amherdt, Bernard Burnand, Murielle Rotzetter, Philippe Currat, Stéphane Roux and Estelle Lécureux (France, Switzerland - J Eval Clin Pract.).
Effect of photobiomodulation therapy on inflammatory cytokines in healing dynamics of diabetic wounds: a systematic review of preclinical studies - Nih.gov
Abstract by Gagana Karkada, G Arun Maiya, Nicolette N Houreld, Praveen Arany, Mohandas Rao Kg, Shalini Adiga, Shobha Ullas Kamath and Somashekar Shetty (India, South Africa - J Eval Clin Pract.).
Visualization of Wound Healing Progression With Near Infrared Spectroscopy: A Retrospective Study - Nih.gov
Abstract by Adam Landsman (Boston, USA - Wounds).
pdf (7,1 mB)!
An Insight into the Role of Non-Porphyrinoid Photosensitizers for Skin Wound Healing - Mdpi.com
Article by Mariana C. S. Vallejo, Nuno M. M. Moura, Maria Amparo F. Faustino, Adelaide Almeida, Idalina Gonçalves, Vanda V. Serra and Maria Graça P. M. S. Neves (Portugal).
Considering the importance of developing photosensitizers with suitable features for this emergent topic concerning skin wound healing, in this review, a special focus on the achievements attained for each photosensitizer class, namely, of the non-porphyrinoid type, is given.
Development and In Vivo Characterization of Probiotic Lysate-Treated Chitosan Nanogel as a Novel Biocompatible Formulation for Wound Healing - Hindawi.com
Article by Yousef Ashoori, Milad Mohkam, Reza Heidari, Seyedeh Narjes Abootalebi, Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Nasim Golkar and Ahmad Gholami (Iran, Taiwan, Singapore - BioMed Research International).
The favorable effects of probiotic lysate nanogels, including the reasonable wound closing rate, good wound appearance, and satisfactory histological observation via in vivo examination, suggest it as a promising nominee for wound healing purposes.
Autologous micrografts and methotrexate in plantar erosive lichen planus: healing and pain control. A case report - Tandofonline.com
Article by G. Miotti , N. Zingaretti, G. F. Guarneri, V. Manfrè, E. Errichetti, G. Stinco and P. C. Parodi (Udine, Italy - Case Reports in Plastic Surgery and Hand Surgery).
The authors report a case of longstanding and refractory plantar ELPS causing disabling and opiate-resistant pain treated with ‘classic’ meshed skin graft combined with Rigenera® micrografts.
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A Novel Herbal Hydrogel Formulation of Moringa oleifera for Wound Healing - Mdpi.com
Article by Cláudia Mouro, Colum P. Dunne and Isabel C. Gouveia (Portugal, Ireland).
The authors' data provide initial confidence that the TEMPO-oxidized cotton/PVA_CS dressing material containing AG extract demonstrates adequate mechanical attributes for use as a wound dressing and represents a promising approach to prevention of bacterial wound contamination.
Indirect Endovascular Revascularization via Collaterals: A New Classification to Predict Wound Healing and Limb Salvage - Annalsofvascularsurgery.com
Abstract by Jenna C. Bekeny, Abdullah Alfawaz, Jonathan Day, Iram Naz, Christopher E. Attinger, Kenneth L. Fan, Karen K. Evans and Cameron M. Akbari (Annals of Vascular Surgery).
Wound-healing activity of Algerian Lavandula stoechas and Mentha pulegium extracts: from traditional use to scientific validation - Tandfonline.com
Abstract by Faiza Baali, Sabah Boumerfeg, Amel Boudjelal, Marcella Denaro, Giovanna Ginestra, Abderrahmane Baghiani, Nadjat Righi, Amirouche Deghima, Faycel Benbacha, Antonella Smeriglio and Domenico Trombetta (Algeria, Italy).
Wound Management Challenges in Prison Populations - Woundsource.com
Article by Cheryl Carver. Wound care management, whether acute or chronic, can be a challenge for both providers and clinicians. However, wound care inside "the walls" adds a unique twist to the complexity. Wound types generally include arterial, venous, pressure, and diabetic neuropathic wounds, subdermal infections, stab wounds, lacerations, and abscesses.
Analyzing the Effects of Stimulant Abuse in Patients With Burns - Physiciansweekly.com
Research has shown that the misuse of illicit stimulants can lead to a variety of negative health consequences, including vasoconstriction, endothelial dysfunction, and hypertension. In addition, chronic use of these stimulants may lead to accelerated atherosclerosis and cardiac dysfunction. “In patients with burns, these factors can reduce the body’s ability for wound healing...
Novel supramolecular self-healing silk fibroin-based hydrogel via host-guest interaction as wound dressing to enhance wound healing - Sciencedirect.com
Abstract by Rui Yu, Yutong Yang, Jiahui He, Meng Li and Baolin Guo (Xi'an, China - Chemical Engineering Journal).
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A Novel Herbal Hydrogel Formulation of Moringa oleifera for Wound Healing - Mdpi.com
Article by Aaliya Ali, Prakrati Garg, Rohit Goyal, Gurjot Kaur, Xiangkai Li, Poonam Negi, Martin Valis, Kamil Kuca and Saurabh Kulshrestha (India, China, Czecz Republic - Plants).
The histopathological investigation confirmed the findings of accelerated regeneration of tissue accompanied by a decrease in inflammatory cells and increased vascularity of the immediate skin. The results (both in vitro and in vivo) claimed conclusively that our n-hexane hydrogel formulation of Moringa oleifera seeds might serve as an alternative therapy in skin restoration during wound healing.
Inter-Rater Reliability of a Pressure Injury Risk Assessment Scale for Home Care: A Multicenter Cross-Sectional Study - Dovepress.com
Article by Masushi Kohta, Takehiko Ohura, Kunio Tsukada, Yoshinori Nakamura, Mishiho Sukegawa, Eiko Kumagai, Yuki Kameda and Toshihiro Kitte (Japan, Journal of Multidisciplinary Healthcare).
The authors' result showed that the PPRA-Home has substantial inter-rater reliability for evaluation of risks of pressure injury development at home care. However, some research focusing on intra-later reliability and validity of the PPRA-Home with adequate sample sizes are required to provide categorical conclusions on whether it can be used for the risk assessment scale in actual clinical settings.
Effects of Negative-Pressure Wound Therapy With Instillation versus Standard of Care in Multiple Wound Types: Systematic Literature Review and Meta-Analysis - Nih.gov
Abstract by Allen Gabriel, Mark Camardo, Erin O'Rorke, Rebecca Gold and Paul J Kim (USA - Plast Reconstr Surg.).
Bacterial Nanocellulose in Dentistry: Perspectives and Challenges - Mdpi.com
Article by Hélida Gomes de Oliveira Barud, Robson Rosa da Silva, Marco Antonio Costa Borges, Guillermo Raul Castro, Sidney José Lima Ribeiro and Hernane da Silva Barud (Brazil, Sweden, Argentina - Molecules).
This review describes the properties and advantages of some BC studies focused on dental and oral applications, including the design of implants, scaffolds, and wound-dressing materials, as well as carriers for drug delivery in dentistry. Aligned to the current trends and biotechnology evolutions, BC-based nanocomposites offer a great field to be explored and other novel features can be expected in relation to oral and bone tissue repair in the near future.
How These Bandages Might Help Speed up Healing - Unreservedmedia.com
Article by Zoe Ibrahim. In the labs of Université Libre de Bruxelles in Brussels right now, scientists are currently hard at work developing a smart bandage prototype. They hope to equip it with sensors that can communicate precious information in real-time on all types of wounds in order to care for them without delay.
Mechano-responsive hydrogel developed for wound healing - Phys.org
Article by Liu Jia. Traditional hydrogels have limited efficacy owing to their poor mechanical properties, skin adhesiveness and drug delivery efficiency. To address this problem, the researchers in this study designed a tough, antibacterial, drug-loaded mechano-responsive zwitterionic hydrogel.
Dysregulated healing responses in diabetic wounds occur in the early stages post injury - Nih.gov
Abstract by Kiara Boodhoo, Mare Vlok, David L Tabb, Kathryn H Myburgh and Mari van de Vyver (Stellenbosch, South Africa - J Mol Endocrinol.).
An exploratory study of risk factors for pressure injury in patients undergoing spine surgery - Nih.gov
Abstract by DaeHee Suh, Su Yeon Kim, Byunghoon Yoo and Sangseok Lee (Anesth Pain Med. (Seoul)).
An exploratory study of risk factors for pressure injury in patients undergoing spine surgery - Nih.gov
Abstract by DaeHee Suh, Su Yeon Kim, Byunghoon Yoo and Sangseok Lee (Anesth Pain Med. (Seoul)).
Comparing the effects of three different multilayer dressings for pressure ulcer prevention on sacral skin after prolonged loading: An exploratory crossover trial - Nih.gov
Abstract by Anna Lechner, Fiorenza Rancan, Sabrina Hadam, Annika Vogt, Ulrike Blume-Peytavi and Jan Kottner (Berlin, Germany - Wound Repair Regen.).
Prevalence, incidence and risk factors for foot pressure ulcers in hospitalized elderly patients. An observational and prospective study - Nih.gov
Abstract by S Garcia, J Alòs, J Guallar, M Viu and M Serra-Prat (Barcelona, Spain - J Healthc Qual Res.).
The Effects of Brazilian Chitosan-Based Biomaterials on Wound Healing in Rats - Sciencedirect.com
Abstract by Vanessa Gaissler, Flavia Tasmin Techera Antunes, Elenir Willand, Sônia Beatriz Scholl Duarte, Cecilia Suzane Pires, Ruth Natali Florentin Machado,
Iasmine Berbigier de Oliveira, Luciano Pighinelli and Alessandra Hubnerde Souza (Rio Grande do Sul, Brazil - Tissue and Cell).
Advances in Gelatin-based Hydrogels for Wound Management - Pubs.rsc.org
Abstract by Jeon Il Kang and Kyung Min Park (Journals of Materials Chemistry B).
Microfluidic guillotine reveals multiple timescales and mechanical modes of wound response in Stentor coeruleus - Biorxiv.org
Article by Kevin S. Zhang, Lucas R. Blauch, Wesley Huang, Wallace F. Marshall and Sindy K. Y. Tang (San Francisco, USA).
The work advances our understanding of the wound response in Stentor, and will lay the foundation for further investigations into the underlying components and molecular mechanisms involved.
The use of Point-of-Care Bacterial Autofluorescence Imaging in the Management of Diabetic Foot Ulcers: A Pilot Randomised Controlled Trial - Woundcarelearningnetwork.com
Poster by David Russell. Diabetic foot ulcers (DFU) have considerable morbidity and mortality, negatively impact patients’ quality of life and are of significant cost to health services. Despite guideline recommended management less than half of DFUs in the UK have healed by 12 weeks. Bacterial autofluorescence imaging has been shown to improve healing of chronic wounds in case series.
The use of Point-of-Care Bacterial Autofluorescence Imaging in the Management of Diabetic Foot Ulcers: A Pilot Randomised Controlled Trial - Woundcarelearningnetwork.com
Poster by Cindy Duong and James McGuire. Wound healing of recalcitrant wounds is challenging, particularly among those with comorbidities and poor immune systems. Venous leg ulcers, caused by chronic venous insufficiency, have profound effects on patients’ quality of life, especially when recurring.
An in vitro model of wound healing in the CNS: Analysis of cell reaction and interaction at different ages - Sciencedirect.com
Abstract by John S. Rudge, George M. Smith and Jerry Silver (Cleveland, USA - Experimental Neurology).
Functional Analysis of Estrogen Receptor 1 in Diabetic Wound Healing: A Knockdown Cell-Based and Bioinformatic Study - Nih.gov
Abstract by Sha Qi, Qiong Han, Danmou Xing, Long Qian, Xiang Yu, Dong Ren, Huan Wang and Quan Chen (Wuhan, China - Med Sci Monit.).
The modified bilobed flap for reconstructing sacral decubitus ulcers - Nih.gov
Abstract by Xiangong Jiao, Chunxiao Cui, Sally Kiu-Huen Ng, Zhangjia Jiang, Chihui Tu, Jiemin Zhou, Xiandong Lu, Xianwen Ouyang, Tong Luo, Ke Li and Yixin Zhang (China - Burns Trauma).
Review: Role of Inflammatory Markers in the Healing Time of Diabetic Foot Osteomyelitis Treated by Surgery or Antibiotics - Woundsource.com
Article by Tardáguila-García A, García-Álvarez Y, Sanz-Corbalán I, Álvaro-Afonso FJ, Molines-Barroso RJ and Lázaro-Martínez JL (J Wound Care).
There was not enough evidence to confirm the role of inflammatory markers in the healing time of osteomyelitis secondary to diabetic foot ulcers, regardless of the treatment administered.
Oncoplastic breast surgery: the role of negative pressure wound therapy - Nih.gov
Abstract by Fahad M Iqbal, Jeremy P Reid and Raghavan Vidya (United Kingdom - J Wound Care).
The effects of felted foam in diabetic foot treatment: systematic review with meta-analysis - Nih.gov
Abstract by Jayana Castelo Branco Cavalcante de Meneses, José Wicto Pereira Borges, Ana Roberta Vilarouca da Silva, Maria Corina Amaral Viana, Vitória de Cassia Félix Rebouças and Ana Maria Parente Garcia Alencar (Brasil - Rev Esc Enferm USP).
Comparative Analysis of The Light Parameters of Red and Near-Infrared Diode Lasers to Induce Photobiomodulation on Fibroblasts and Keratinocytes: an in vitro study - Nih.gov
Abstract by Nermin Topaloglu, Merve Özdemir and Ziyşan Buse Yaralı Çevik (Izmir, Turkey - Photodermatol Photoimmunol Photomed.).
Assessing the Need for Negative Pressure Wound Therapy Utilization Guidelines: An Overview of the Challenges With Providing Optimal Care - Woundresearch.com
Article by Robert S. Kirsner and Theresa Hurd (Wounds). Evidence-based recommendations are needed to guide decisions regarding NPWT systems, which in turn may improve therapy implementation, access to care, and patient quality of life, while driving operational and financial efficiencies for health care providers.
Remote Wound Care - Woundresearch.com
Article by Laura Bolton (Wounds). With the increasing global presence of and reliance on smartphones, featuring high-resolution digital photography and wireless, high-speed Internet, patients with wounds and point-of-care wound professionals are increasingly engaged in remote wound management and surveillance.
Treatment of Burns in Adult Patients With a Concentrated Surfactant Gel: A Real-life Retrospective Evaluation - Woundresearch.com
Article by Timothy Pittinger, Danielle Curran and Michel Hermans (Wounds). On average, the CSG-BA–treated burns were less deep and smaller than the CSG alone. All wounds reached complete healing or showed continued healing progress.
Use of Polymeric Membrane Dressings for Debridement of Wounds in Extreme Premature Infants < 25 Weeks Gestation - Woundcarelearningnetwork.com
Abstract by Rene A Amaya.
Pilot Study Evaluating Diagnostic Tissue Biomarkers to Predict Healing Outcome and Guide Debridement in Chronic Venous Leg Ulcers - Woundcarelearningnetwork.com
Abstract by Rashmika Reddy, Cheyanne Head, Jelena Marjanovic, Rivka Stone, Ivan Jozic, Irena Pastar and Marjana Tomic-Canic.
Topical oxygen therapy has a role in wound care specialists’ armamentarium - Iwoundsnews.com
Thomas Serena, principal investigator of the recently completed Natrox clinical trial—a randomised controlled multicentre trial examining the effect of topical oxygen wound therapy on the healing rate of chronic diabetic foot ulcers—provides an overview of the pros and cons of topical oxygen therapy.
Decades of data show hyperbaric oxygen therapy belongs in the diabetic foot ulcer treatment algorithm - Iwoundsnews.com
The five-year mortality rate after a major amputation is approximately 50%. By preventing these amputations, physicians treating patients with Wagner Grade III or worse diabetic foot ulcers significantly improve the quality of life of these patients.
Maggot debridement therapy in critical limb ischaemia: a case study - Nih.gov
Abstract by Taku Maeda, Yuhei Yamamoto, Naoki Murao, Toshihiko Hayashi, Chu Kimura, Suguru Matsui, Tatsuya Saito, Hotaka Matsui, Masayuki Osawa and Emi Funayama (Hokkaido, Japan - J Wound Care).
Recent strategic approach in postburn extremity scars and contractures - Nih.gov
Abstract by Percin Karakol and Mehmet Bozkurt (Istanbul, Turkey - J Plast Surg Hand Surg.).
Comparison of the effects of Lactobacillus plantarum versus imipenem on infected burn wound healing - Nih.gov
Abstract by Somayeh Soleymanzadeh Moghadam, Nazanin Mohammad, Maryam Ghooshchian, Sara FathiZadeh, Zohreh Khodaii, Mahmood Faramarzi, Zeinab Fagheei Aghmiyuni, Masoud Roudbari, Abdolreza Pazouki and Tahereh Mousavi Shabestari (Iran - Med J Islam Repub Iran).
Role of Spider Silk in Biomedicine - Medical.net
Article by Benedette Cuffari. Silk is a fibrous protein that is synthesized in the specialized epithelial cells that can be found surrounding the glands of various types of insects. The most common sources of silk include worms of the order Lepidoptera, which include organisms like mites, butterflies and moths, as well as several members of the Arachnida class of organisms, which consists of over 30,000 different species of spiders.
Remote ischaemic conditioning works “from the inside out” to heal perfusion-ischaemic wounds - Iwoundsnews.com
Remote ischaemic conditioning is a “really innovative technology” that can be used as an adjunctive therapy to significantly reduce tissue damage from an interrupted blood supply.
First case of continuous topical oxygen therapy healing a calciphylaxis wound presented at SAWC - Iwoundsnews.com
Windy Cole concluded that topical oxygen therapy offers an effective, non-invasive wound treatment that may speed healing in chronic non-healing wounds of various aetiologies that were recalcitrant to other advanced wound therapies.
The effects of shock wave therapy applied on hypertrophic burn scars: a randomised controlled trial - Nih.gov
Abstract by Peter Moortgat, Mieke Anthonissen, Ulrike Van Daele, Tine Vanhullebusch, Koen Maertens, Lieve De Cuyper, Cynthia Lafaire and Jill Meirte (Belgium - Scars Burn Heal.).
The Incidence of Pressure Ulcers and its Associations in Different Wards of the Hospital: A Systematic Review and Meta-Analysis - Nih.gov
Abstract by Lotfolah Afzali Borojeny, Ahmed N Albatineh, Ali Hasanpour Dehkordi and Reza Ghanei Gheshlagh (Kuwait, Iran - Int J Prev Med.).
How a Burn and Wound Clinic Improved Staff Nurse Retention Through Peer Interviewing - Todayswoundclinic.com
Article by Kathleen Prestifilippo, Emily Webb, Fred Mullins, Shawn Fagan, Zaheed Hassan, Bounthavy Homsombath, Beretta Craft-Coffman, Cynthia Currington, Meganjoy Whelan and Joan Wilson (Augusta, USA).
Facing burnout, a lack of autonomy, inadequate facilities and other issues, nurses frequently leave their wound care facilities. Using a peer interview process for hiring helped these authors forge a united and efficient team, as well as achieve facility compliance at their burn and wound clinic.
Effect of Concentrated Surfactant Gel-based Dressing on the Wound Bed in Patients with Burn and Chronic Wounds - Woundcarelearningnetwork.com
Abstract by Matthew M Melin, Jennifer Reinders, Angie Wubben and Katie Cecconi.
Effects of Strong Acidic Electrolyzed Water in Wound Healing via Inflammatory and Oxidative Stress Response - Hindawi.com
Article by Ailyn Fadriquela, Ma Easter Joy Sajo, Johny Bajgai, Dong-Heui Kim, Cheol-Su Kim, Soo-Ki Kim and Kyu-Jae Lee (Wonju, Republic of Korea).
This study has proven the wound healing effect of StAEW and its earlier mediation through oxidative and inflammatory responses.
Fully automatic wound segmentation with deep convolutional neural networks - Nature.com
Article by Chuanbo Wang, D. M. Anisuzzaman, Victor Williamson, Mrinal Kanti Dhar, Behrouz Rostami, Jeffrey Niezgoda, Sandeep Gopalakrishnan and Zeyun Yu (Milwaukee, USA).
The authors demonstrate the effectiveness and mobility of their method by conducting comprehensive experiments and analyses on various segmentation neural networks.
HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism - Nature.com
Article by Sampath Narayanan, Sofie Eliasson Angelstig, Cheng Xu, Jacob Grünler, Allan Zhao, Wan Zhu, Ning Xu Landén, Mona Ståhle, Jingping Zhang, Mircea Ivan, Raluca Georgiana Maltesen, Ileana Ruxandra Botusan, Neda Rajamand Ekberg, Xiaowei Zheng and Sergiu-Bogdan Catrina (Sweden, China, USA).
miR-210 accelerates wound healing specifically in diabetes through improvement of the cellular metabolism.
A Fibroblast-Derived Human Growth Factor Preparation for the Management of Acute Radiodermatitis: A Case Report - Dovepress.com
Article by Georgia Vadarli and Maria Angelo-Khattar (Dubai, United Arab Emirates - International Medical Case Reports Journal).
This case study outlines the management of a grade 3 acute radiodermatitis in a female with a synergistic preparation of anti-inflammatory cytokines and growth factors derived from human fibroblasts. The treatment resulted in the total resolution of the radiation-induced skin reaction, with a minimally visible residual scar.
Autocrine insulin pathway signaling regulates actin dynamics in cell wound repair - Nih.gov
Abstract by Mitsutoshi Nakamura, Jeffrey M Verboon, Tessa E Allen, Maria Teresa Abreu-Blanco, Raymond Liu, Andrew N M Dominguez, Jeffrey J Delrow and Susan M Parkhurst (Seattle, USA - PLoS Genet.).
How our immune system uses memory to treat injuries - Deccanherald.com
Every injury or infection trains the immune system to remember the wound which allows it to better handle future injuries.
Cord Blood Platelet Gel Leads to Faster Wound Healing in RDEB Children, Study Says - Epidermolysisbullosanews.com
Article by Patricia Inacio. A gel made from platelets — tiny cells involved in blood clotting — that were collected from umbilical cord blood was better and faster at promoting wound healing in children with recessive dystrophic epidermolysis bullosa (RDEB) than a standard approach, a pilot study found.
Convergence of 3D printed biomimetic wound dressings and adult stem cell therapy - Nih.gov
Abstract by Abbas Shafiee, Amanda S Cavalcanti, Navid T Saidy, Dominik Schneidereit, Oliver Friedrich, Akhilandeshwari Ravichandran, Elena M De-Juan-Pardo and Dietmar W Hutmacher (Australia, Biomaterials).
Anti-inflammatory, wound healing and antioxidant potential of compounds from Dioscorea bulbifera L. bulbils - Plos.org
Article by Prapaporn Chaniad, Supinya Tewtrakul, Teeratad Sudsai, Supat Langyanai and Kantarakorn Kaewdana.
The authors' findings provide more evidence to support the traditional use of D. bulbifera for the treatment of wounds and inflammation.
The plasminogen receptor, Plg-RKT, plays a role in inflammation and fibrinolysis during cutaneous wound healing in mice - Nature.com
Article by Lina Ny, Robert J. Parmer, Yue Shen, Sandra Holmberg, Nagyung Baik, Assar Bäckman, Jessica Broden, Malgorzata Wilczynska, Tor Ny and Lindsey A. Miles (USA, Sweden).
Plg-RKT is a new regulator participating in different phases of cutaneous burn wound healing, which coordinately plays a role in the interrelated responses of inflammation, keratinocyte migration, and fibrinolysis.
Value-based Healthcare: Using Human Fibroblast-derived Dermal Substitute in the Treatment of Diabetic Foot Ulcers - Woundcarelearningnetwork.com
Poster abstract by Aseel Bin Sawad, Vipul Dev and Quan Pho. To reduce overall healthcare costs, healthcare plans should continue HFDS coverage and encourage clinicians to expand use of HFDS for the treatment of DFUs.
Evaluation of Effects of Continuous Topical Oxygen Therapy on Diabetic Foot Ulcers - Woundcarelearningnetwork.com
Abstract by Scott Ellis, Matthew Carpiniello, John Lantis II, Munir Patel and Emily Pesek. As one potential option for wound healing devices for diabetic foot ulcers, topical oxygen therapy was well tolerated by our patient population and demonstrated improved wound healing consistently.
Degloving Soft Tissue Injuries of the Extremity: Characterization, Categorization, Outcomes, and Management - Nih.gov
Abstract by Christine Velazquez, Litton Whitaker and Ivo A Pestana (Winston-Salem, USA - Plast Reconstr Surg Glob Open).
Skin wound closure delay in metabolic syndrome correlates with SCF deficiency in keratinocytes - Nature.com
Article by Zhenping Wang, Yanhan Wang, Nicholas Bradbury, Carolina Gonzales Bravo, Bernd Schnabl and Anna Di Nardo (San Diego, USA - Scientific Reports).
This discovery is imperative for developing clinical strategies that might improve the body’s natural repair mechanisms for treating patients with wound-closure pathologies.
Human gingival fibroblast secretome accelerates wound healing through anti-inflammatory and pro-angiogenic mechanisms - Nature.com
Article by Parinaz Ahangar, Stuart J. Mills, Louise E. Smith, Stan Gronthos and Allison J. Cowin (Adelaide, Australia - npj Regenerative Medicine).
The authors's findings demonstrate that treatment of dermal wounds with either hGFs or hGF-CM may provide beneficial gingival-like properties to dermal wounds and may be a potential opportunity for improving healing of the skin.
The complex role of Prostaglandin E 2-EP receptor signaling in wound healing - Nih.gov
Abstract by Kristy E Gilman and Kirsten H Limesand (Tucson, USA - Am J Physiol Regul Integr Comp Physiol.).
Trends in Decubitus Ulcer Disease Burden in European Union 15+ Countries, from 1990 to 2017 - Nih.gov
Abstract by Richard Goodall, Alexander Armstrong, William Hughes, Charles A Fries, Dominic Marshall, Eleanor B Harbinson, Justin Salciccioli and Joseph Shalhoub (UK - Plast Reconstr Surg Glob Open).
Bidirectional Irrigation System to Treat a Difficult Wound: A Case Series - Nih.gov
Abstract by Li-Yung Chen, Jin-De Hou and Chian-Ze Peng (Taiwan - Int J Low Extrem Wounds).
Phytochemical Profile, Safety Assessment and Wound Healing Activity of Artemisia absinthium L. - Mdpi.com
Article by Amel Boudjelal, Antonella Smeriglio, Giovanna Ginestra, Marcella Denaro and Domenico Trombetta (Algeria, Italy - Plants).
Data collected in the present study support and validate the use of A. absinthium as a wound healing agent in the Algerian traditional medicine.
Four new and upcoming technologies in wound healing and regeneration - Nsmedicalnews.com
Article by Peter Littlejohns. New technologies in the pipeline for wound healing include lasers that kill bacteria and flourescent imaging to aid diagnoses.
Medical adhesive material trends - Todaysmedicaldevelopments.com
Medical adhesive materials have significantly evolved since 1980, with innovation closely linked to healthcare quality, environmental sustainability, cost controls, and better workplace and product safety.
Design and evaluation of ciprofloxacin loaded collagen chitosan oxygenating scaffold for skin tissue engineering - Nih.gov
Abstract by Satyavrat Tripathi, Bhisham Narayan Singh, Singh Divakar, Gaurav Kumar, Sarada Prasanna Mallick and Pradeep Srivastava (India - Biomed Mater.).
Autologous Fat Grafting Promotes Macrophage Infiltration to Increase Secretion of Growth Factors and Revascularization, Thereby Treating Diabetic Rat Skin Defect - Dovepress.com
Article by Yu Wang, Hao Zhang, Min Zhou, Xinzeyu Yi, Ping Duan, Aixi Yu and Baiwen Qi (Wuhan, China - Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy).
AFG promotes the infiltration of macrophages to improve the healing environment of diabetic wounds by increasing the secretion of growth factors and revascularization, which provides a potential method for the treatment of diabetic skin defects.
Artificial synthetic spider silk maybe used in wound healing - Indiatimes.com
Researchers for the first time showed how 'click-chemistry' can be used to attach molecules, such as antibiotics or fluorescent dyes, to artificially produced spider silk synthesised by E coli bacteria.
Homogeneous and efficient production of a bacterial nanocellulose-lactoferrin-collagen composite under an electric field as a matrix to promote wound healing - Nih.gov
Abstract by Haibin Yuan, Lin Chen and Feng F Hong (Shanghai, China - Biomater Sci.).
The Adjunct Use of Platelet-Rich Plasma in Split-Thickness Skin Grafts: A Systematic Review - Nih.gov
Abstract by Austin Dunn, Tyler Long, Raymond E Kleinfelder and Matthew Belisario Zarraga (Chicago, USA - Adv Skin Wound Care).
Topical Application of Fibroblast Growth Factor 10-PLGA Microsphere Accelerates Wound Healing via Inhibition of ER Stress - Hindawi.com
Article by Ke Xu, Bo Chai, Kailun Zhang, Jun Xiong, Yiru Zhu, Jingyu Xu, Ningchen An, Weidong Xia, Hao Ji, Yanqing Wu, Hao Li, Jian Xiao, Zhiguo Feng and Hongyu Zhang (Zhejiang, China - Oxidative Medicine and Cellular Longevity).
This study indicates that FGF10-PLGA microspheres accelerate wound healing presumably through modulating ER stress.
Polycaprolactone based electrospun matrices loaded with Ag/hydroxyapatite as wound dressings: Morphology, cell adhesion and antibacterial activity - Nih.gov
Abstract by Abeer A Hassan, Hyam A Radwan, Said A Abdelaal, Najlaa S Al-Radadi, M K Ahmed, Kamel Shoueir and Mayssa Abdel Hady (Egypt, Saudi Arabia - Int J Pharm.).
Modeling early thermal injury using an ex vivo human skin model of contact burns - Nih.gov
Abstract by Aiping Liu, Edgar Ocotl, Aos Karim, Josiah J Wolf, Benjamin L Cox, Kevin W Eliceiri and Angela L F Gibson (Madison, USA - Burns).
Burden Of Groin Wound Complications After Vascular Surgery Involving The Femoral Vessels - Nih.gov
Abstract by Joana Cruz Silva, Vânia Constâncio Oliveira, Pedro Lima, Mafalda Correia, Mário Moreira and Gabriel Anacleto (Coimbra, Portugal - Rev Port Cir Cardiotorac Vasc.).
Healing Process of Rat Skin Wounds Treated With Vitamin C and Low-Intensity Laser Therapy - Cureus.com
Article by Luis Flavio Duraes Gomes Oliva and Doroty Mesquita Dourado. The present findings suggest that in spite of all treatments being effective in the repair of skin wounds compared to the control group, the isolated use of low-intensity therapy laser and its combined use with topical vitamin C showed the most favorable results, indicating that those could be further used for the treatment of skin wounds.
Simvastatin accelerates the healing process of burn wound in Wistar rats through Akt/mTOR signaling pathway - Nih.gov
Abstract by Parisa Ramhormozi, Javad Mohajer Ansari, Sara Simorgh, Hamid Reza Asgari, Mohammad Najafi, Mahmood Barati, Azar Babakhani and Maliheh Nobakht (Iran - Ann Anat.).
Effects of the Traditional Chinese Medical Prescription Linba Fang as a Treatment for Lymphedema - Nih.gov
Abstract by Y Luo, L Zhao and N F Liu (Shanghai, China - Evid Based Complement Alternat Med.).
RUDN University medics created a wound-healing gel with metabolic products of trichoderma - Eurekalert.org
The best way to treat skin damage is to accelerate cell regeneration using ointments with different active ingredients such as metabolic products of microorganisms. Fungi, bacteria, and other organisms produce antibiotics, enzymes, growth promoters, vitamins, and amino acids, and scientists are always looking for ways to turn them into medicinal drugs. One of these useful substances is L-lysine-oxidase produced by Trichoderma fungi.
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Experimental Study on Blue Light Interaction with Human Keloid-Derived Fibroblasts - Mdpi.com
Article by Giada Magni, Martina Banchelli, Federica Cherchi, Elisabetta Coppi, Marco Fraccalvieri, Michele Rossi, Francesca Tatini, Anna Maria Pugliese, Duccio Rossi Degl’Innocenti, Domenico Alfieri, Paolo Matteini, Roberto Pini, Francesco S. Pavone and Francesca Rossi (Florence, Italy - Biomedicines).
The authors" data demonstrate the potentials that PBM shows as an innovative and minimally-invasive approach in the management of hypertrophic scars and keloids, in association with current treatments.
In Vitro Characterization of Pressure Redistribution Among Commercially Available Wound Dressings - Nih.gov
Abstract by Jeffrey A Niezgoda, Jonathan A Niezgoda and Sandeep Gopalakrishnan (Millwaukee, USA - Adv Skin Wound Care).
Outcomes of Wound Care Nurses' Practice in Patients with Pressure Ulcers: An Integrative Review - Nih.gov
Abstract by Dario Monaco, Paolo Iovino, Marzia Lommi, Giulia Marano, Francesco Zaghini, Ercole Vellone, Rosaria Alvaro and Alessandro Sili (Australia, Italy - J Clin Nurs.).
Gas plasma-spurred wound healing is accompanied by regulation of focal adhesion, matrix remodeling, and tissue oxygenation - Nih.gov
Abstract by Anke Schmidt, Grit Liebelt, Felix Nießner, Thomas von Woedtke and Sander Bekeschus (Greifswald, Germany - Redox Biol.).
5 Outdated Wound Care Practices: Do You Still Use These? - Woundsource.com
In a recent survey, the authors asked the WoundSource Editorial Advisory Board members what outdated wound care practices they continue to see in the field. Depending on what health care setting clinicians work in, there are specific guidelines, policies, and procedures that may impact standard of care.
The Combined Use of Negative-Pressure Wound Therapy and Dermal Substitutes for Tissue Repair and Regeneration - Hindawi.com
Article by Liping Zhang, Tingting Weng, Pan Wu, Qiong Li, Chunmao Han and Xingang Wang (Zheijang, China - BioMed Research International).
This article presents a comprehensive overview of the combined use of NPWT and dermal substitutes for tissue repair and regeneration. Relative concerns and prospects are also discussed.
The Comparative Efficacy of Conventional Short-Stretch Multilayer Bandages and Velcro Adjustable Compression Wraps in Active Treatment Phase of Patients with Lower Limb Lymphedema - Nih.gov
Abstract by Pinar Borman, Esra G Koyuncu, Ayşegül Yaman, Emel Calp, Funda Koç, Rüveyda Sargut and Sevilay Karahan (Turkey - Lymphat Res Biol.).
Strategies and challenges in the treatment of chronic venous leg ulcers - Nih.gov
Abstract by Shi-Yan Ren, Yong-Sheng Liu, Guo-Jian Zhu, Meng Liu, Shao-Hui Shi, Xiao-Dong Ren, Ya-Guang Hao and Rong-Ding Gao (China - World J Clin Cases).
A literature review of pharmacological agents to improve venous leg ulcer healing - Woundresearch.com
Article by M. Mark Melin and Steven M. Dean (Wounds). Micronized purified flavonoid fraction is composed of diosmin glycoside, diosmin being converted from hesperidin (found in citrus). The MPFF composition is typically 90% diosmin, 10% hesperidin, and related compounds.
Symptomatic Alleviation of Painful Venous Leg Ulcers Using a Fish Skin Acellular Dermal Matrix - Woundcarelearningnetwork.com
Poster-abstract by Scott Ellis, Matthew Carpiniello, John Lantis II, Munir Patel and Emily Pesek.
Pilot Study Evaluating Diagnostic Tissue Biomarkers to Predict Healing Outcome and Guide Debridement in Chronic Venous Leg Ulcers - Woundcarelearning network.com
Poster-abstract by Rashmika Reddy, Cheyanne Head, Jelena Marjanovic, Rivka Stone, Ivan Jozic, Irena Pastar and Marjana Tomic-Canic.
Evaluation of Efficacy of a Concentrated Surfactant Gel-based Dressing in Non-Venous Leg Ulcers in a Population with Limited Resources - Woundcarelearningnetwork.com
Poster-abstract by Debashish Chakravarthy, Isabelle Lazareth, Christine Moffat, Joachim Dissemond, Serge Bohbot and Sylvie Meaume.
Skin Ulcers: Wound Management - Nih.gov
Abstract by Brian Z Rayala (Chapel Hill, USA - FP Essent.).
Potential Applications of Nanomaterials and Technology for Diabetic Wound Healing - Dovepress.com
Article by Que Bai, Kai Han, Kai Dong, Caiyun Zheng, Yanni Zhang, Qianfa Long and Tingli Lu (Xi’an, China - International Journal of Nanomedicine).
Nanoparticles/hydrogels can be combined with some technology (including PTT, LBL self-assembly technique and 3D-printing technology) to treat diabetic wound repair. By reviewing the recent literatures, the authors also proposed new strategies for improving multifunctional treatment of diabetic wounds in the future.
Lactobacillus reuteri DSM 17938 Increased the Fibroblast Count in the Wound Healing Process on Diabetic Wistar Rats - Ijsr.net
Article by Kezia Natania, Ida Sri Iswari and Ni Wayan Winarti (Indonesia - International Journal of Science and Research).
Lactobacillus reuteri DSM 17938 increased the fibroblasts counts on day five but did not improve neovascularization and re-epithelialization in diabeticmale Wistar rats; nevertheless, the probiotic showed a potential positive effect.
Vibration enhanced cell growth induced by surface acoustic waves as in vitro wound-healing model - Nih.gov
Abstract by Manuel S Brugger, Kathrin Baumgartner, Sophie C F Mauritz, Stefan C Gerlach, Florian Röder, Christine Schlosser, Regina Fluhrer, Achim Wixforth and Christoph Westerhausen (Germany - Proc Natl Acad Sci U S A.).
Sensors for a ‘Smart’ Wound Bandage May Track Healing, Immune Response: Study - Enn.com
Researchers from Skoltech and the University of Texas at Austin have presented a proof-of-concept for a wearable sensor that can track healing in sores, ulcers and other kinds of chronic skin wounds, even without the need to remove the bandages.
Human decellularized adipose matrix derived hydrogel assists mesenchymal stem cells delivery and accelerates chronic wound healing - Nih.gov
Abstract by Zhaoyang Chen, Bowen Zhang, Jun Shu, Haiyang Wang, Yudi Han, Quan Zeng, Youbai Chen, Jiafei Xi, Ran Tao, Xuetao Pei, Wen Yue and Yan Han (Beijing, China - J Biomed Mater Res A.).
Negative pressure wound therapy for prevention of surgical site infection in patients at high risk after clean-contaminated major pancreatic resections: A single-center, phase 3, randomized clinical trial - Nih.gov
Abstract by Stefano Andrianello, Luca Landoni, Cecilia Bortolato, Livio Iudici, Massimiliano Tuveri, Antonio Pea, Matteo De Pastena, Giuseppe Malleo, Deborah Bonamini, Gessica Manzini, Claudio Bassi and Roberto Salvia (Verona, Italy - Surgery).
Polyvinyl alcohol and pectin blended films: preparation, characterization and mesenchymal stem cells attachment - Nih.gov
Abstract by Aliaksandr Kraskouski, Kseniya Hileuskaya, Viktoryia Kulikouskaya, Volha Kabanava, Vladimir Agabekov, Sergei Pinchuk, Irina Vasilevich, Igor Volotovski, Tatyana Kuznetsova and Vasilina Lapitskaya (Minsk, Belarus - J Biomed Mater Res A.).
Curcumin nanoparticles incorporated in PVA/collagen composite films promote wound healing - Tandofonline.com
Article by QingQing Leng, Yue Li, XianLun Pang, BiQiong Wang, ZhouXue Wu, Yun Lu, Kang Xiong, Ling Zhao, Ping Zhou and ShaoZhi Fu (Luzhou, China - Drug Delivery).
Results of authors' in vivo evaluation revealed that the CPCF (composite film) was suitable for wound management and promoted wound healing. Therefore, CPCF may be used as an effective wound dressing and also shows potential in skin tissue engineering.
Snail slime central to sustainable strategy for making wound-healing gold nanoparticles - Chemistryworld.com
Article by Alexandra Klein. Gold nanoparticles made by combining snail slime with colloidal gold can promote wound healing, new research shows. The synthetic strategy avoids the harsh conditions typically associated with making gold nanoparticles by using the snail secretions as reducing agents.
Scratch-induced partial skin wounds re-epithelialize by sheets of independently migrating keratinocytes - Life-science-alliance.org
Article by Laura Bornes, Reinhard Windoffer, Rudolf E Leube, Jessica Morgner and Jacco van Rheenen.
Wound-induced cell loss is replenished by proliferation in a distinct zone away from the wound and this proliferation does not affect overall migration pattern. Whereas suprabasal keratinocytes are rather passive, basal keratinocytes move as a sheet of independently migrating cells into the wound, thereby constantly changing their direct neighboring cells enabling them to bypass intact obstacles. This re-epithelialization strategy results in a fast re-establishment of the protective skin barrier upon wounding.
Constructing Inpatient Pressure Injury Prediction Models Using Machine Learning Techniques - Nih.gov
Abstract by Ya-Han Hu, Yi-Lien Lee, Ming-Feng Kang and Pei-Ju Lee (Chiayi, Taiwan - Comput Inform Nurs.).
Metabolite Characterization and Correlations with Antioxidant and Wound Healing Properties of Oil Palm (Elaeis guineensis Jacq.) Leaflets via 1H-NMR-Based Metabolomics Approach - Mdpi.com
Article by Mohamad Shazeli Che Zain, Soo Yee Lee, Nadiah Mad Nasir, Sharida Fakurazi and Khozirah Shaari (Serdang, Malaysia - Molecules).
This study has provided crucial evidence on the importance of the natural antioxidant compounds on the wound healing properties of OPL.
Multifunctional chitosan-copper-gallic acid based antibacterial nanocomposite wound dressing - Nih.gov
Abstract by Xinyu Sun, Mengna Dong, Zhirong Guo, Hui Zhang, Jiao Wang, Pei Jia, Tong Bu, Yingnan Liu, Lihua Li and Li Wang (Yangling, China - Int J Biol Macromol.).
Salvaging exposed microtia cartilage framework with negative pressure wound therapy - Nih.gov
Abstract by Kaoru Sasaki, Masahiro Sasaki, Junya Oshima, Akio Nishijima, Yukiko Aihara and Mitsuru Sekido (Tsukuba, Japan - J Plast Reconstr Aesthet Surg.).
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