Hungarian Wound Care Society

Nanocarrier-Mediated Topical Insulin Delivery for Wound Healing - Mdpi.com
Article by Ana S. Macedo, Francisca Mendes, Patrícia Filipe, Salette Reis and Pedro Fonte (Portugal - Materials). The encapsulation into nanoparticles improves its stability in the wound, providing adhesion to the mucosal surface and allowing its sustained release. The aim of this review is to perform a standing point about a promising strategy to treat different types of wounds by the topical delivery of insulin-loaded nanocarriers.

What you need to know about gangrene - Medicalnewstoday.com
Gangrene happens when a lack of oxygen-rich blood causes tissue to die in some part of the body, often the hands or feet. It is a serious condition that can result in amputation of a limb or death. It needs urgent treatment to halt the spreadTrusted Source of tissue death as rapidly as possible.

Prevalence, incidence, length of stay and cost of healthcare-acquired pressure ulcers in pediatric populations: A systematic review and meta-analysis - PubMed
Abstract by Christos Triantafyllou, Evangelia Chorianopoulou, Eleni Kourkouni, Theoklis E Zaoutis and Georgia Kourlaba (Athens, Greece - Int J Nurs Stud.).

Negative Pressure Wound Therapy Reduced Amputation Risk for Patient With Diabetic Wound - Ajmc.com
Article by Skylar Jeremias. A patient with a diabetic foot wound who underwent negative pressure wound therapy experienced good healing, reduced amputation risk, and no wound infection, suggesting the treatment method could be effective in other patients with similar wounds.

Educating Your Patients About Wound Care and the Wound Healing Process - Woundsource.com
Patient education should be a priority to empower patients to care for themselves and improve patient outcomes. Involving patients in their own care can help them to understand about their wound and be more adherent to the overall treatment plan. Remember to involve the caregiver or family if applicable.

Arterial Ulcers - Woundsource.com
Arterial ulcers, also referred to as ischemic ulcers, are caused by poor perfusion (delivery of nutrient-rich blood) to the lower extremities. The overlying skin and tissues are then deprived of oxygen, killing these tissues and causing the area to form an open wound. In addition, the lack of blood supply can result in minor scrapes or cuts failing to heal and eventually developing into ulcers.

Case Study: Medical Device-Related Pressure Injury Treatment Using DACC Technology Dressings - Woundsource.com
Article by Charles P. Buscemi. Urinary catheters serve several purposes, including monitoring urine output, relieving urinary retention, and facilitating diagnosis of disease in the lower urinary tract. These catheters can be inserted easily and are universally available, which usually results in their continued and indiscriminate usage. Urinary catheters can be indwelling or external-condom types.

Biohydrogel Based on Dynamic Covalent Bonds for Wound Healing Applications - Mdpi.com
Article by Chukwuma O. Agubata, Cynthia C. Mbaoji, Ifeanyi T. Nzekwe, César Saldías and David Díaz Díaz (Nigeria, Chile, Spain, Germany - Applied Sciences). The PBA-Alg hydrogels exhibit self-healing dynamic covalent interactions and may be useful in dressings for incision wounds.

Revealing How the Body Discovers and Responds to Wounds - Technologynetworks.com
A new study from Vanderbilt University researchers has established a novel way to understand how the body discovers and responds to wounds.

Machine learning analysis of multispectral imaging and clinical risk factors to predict amputation wound healing - Healtheuropa.eu
Abstract by John J Squiers, Jeffrey E Thatcher, David Bastawros, Andrew J Applewhite, Ronald D Baxter, Faliu Yi, Peiran Quan, Shuai Yu, J Michael DiMaio and Dennis R Gable (USA - J Vasc Surg.).

Innovations in hydrogel technology are transforming wound care - PubMed
Using revolutionary technology, hydrogel wound care can help prevent unnecessary infection and heal wounds before they become chronic.

Nanofibrous composite aerogel with multi-bioactive and fluid gating characteristics for promoting diabetic wound healing - Sciencedirect.com
Article by Kexin Zhang, Xiangyu Jiao, Liping Zhou, Jian Wang, Cheng Wang, Yan Qin and Yongqiang Wen (Beijing, China - Biomaterials). Experiments in diabetic mice model showed that Janus nanofibrous aerogel can prevent maceration of peri-wound tissue, shorten the inflammation phase, and promote diabetic wound healing. Its good elasticity and easy production characteristics are friendly for clinical application.

How can nanofibers aid successful wound healing? - Healtheuropa.eu
Dr Shahin Homaeigohar speaks to Health Europa Quarterly (HEQ) about the wound healing potential of nanofibrous dressings.

A multimodal antimicrobial platform based on MXene for treatment of wound infection - PubMed
Abstract by Xia Xu, Shige Wang, Hang Wu, Yanfang Liu, Fei Xu and Jiulong Zhao (Shanghai, China - Colloids Surf B Biointerfaces).

Risk factors of medical device-related pressure injury in intensive care units - PubMed
Abstract by Wen Dang, Yuan Liu, Qing Zhou, Yuyu Duan, Huaxiu Gan, Lin Wang, Qiongli Zhu, Chunyan Xie and Ailing Hu (China - J Clin Nurs.).

Compression bandages or stockings versus no compression for treating venous leg ulcers - PubMed
Abstract by Chunhu Shi, Jo C Dumville, Nicky Cullum, Emma Connaughton and Gill Norman (Manchester, UK - Cochrane Database Syst Rev.).

Myofibroblasts: Function, Formation, and Scope of Molecular Therapies for Skin Fibrosis - Mdpi.com
Article by Yifan Tai, Emma L. Woods, Jordanna Dally, Deling Kong, Robert Steadman, Ryan Moseley and Adam C. Midgley (China, UK - Biomolecules). This comprehensive review article describes the myofibroblast cell phenotype, their origins, and their diverse physiological and pathological functionality. Special attention has been given to mechanisms and molecular pathways governing myofibroblast differentiation, and updates in molecular interventions.

Exploring the Role of Pain as an Early Indicator for Individuals at Risk of Pressure Ulcer Development: A Systematic Review - PubMed
Abstract by Hannah Wilson, Zena Moore, Pinar Avsar, Aglecia Moda Vitoriano Budri, Tom O'Connor, Linda Nugent and Declan Patton (Ireland, Australia, Belgium, China, UK, Saudi-Arabia - Worldviews Evid Based Nurs.).

Decreasing the Likelihood of Multiple Organ Dysfunction Syndrome in Burn Injury with Early Antioxidant Treatment - Mdpi.com
Article by Jackson P. Sterling and Vincent C. Lombardi (Reno, USA - Antioxidants). The authors discuss the current research and advancements in the treatment of burn trauma with the use of antioxidants, and how the early administration of antioxidant can possibly reduce the risk of developing multiple organ dysfunction syndrome (MODS).

Wound Dehiscence - Teachmesurgery.com
Wound dehiscence is where a wound fails to heal, often re-opening a few days after surgery (most common in abdominal surgery). It can be divided into two clinical entities: Superficial dehiscence and Full thickness dehiscence.

Skin-inspired gelatin-based flexible bio-electronic hydrogel for wound healing promotion and motion sensing - PubMed
Abstract by Manhui Zheng, Xuechuan Wang, Ouyang Yue, Mengdi Hou, Huijie Zhang, Sebastian Beyer, Anna Maria Blocki, Qin Wang, Guidong Gong, Xinhua Liu and Junling Guo (China - Biomaterials).

3D-printed antioxidant antibacterial carboxymethyl cellulose/ε-polylysine hydrogel promoted skin wound repair - PubMed
Abstract by Xiaoxue Wang, Jingjie Qi, Wenjie Zhang, Yajie Pu, Rong Yang, Penghui Wang, Shuai Liu, Xiaoyan Tan and Bo Chi (Nanjing, China - Int J Biol Macromol.).

Skin Physiology and its Microbiome as Factors Associated with the Recurrence of Pressure Injuries - PubMed
Abstract by Kana Shibata, Kazuhiro Ogai, Kohei Ogura, Tamae Urai, Miku Aoki, Defa Arisandi , Natsuki Takahashi, Shigefumi Okamoto, Hiromi Sanada and Junko Sugama (Japan, Indonesia - Biol Res Nurs.).

Skin Wound Healing Rate in Fish Depends on Species and Microbiota - Mdpi.com
Article by Tery Yun, Soeun Shin, Kyungwon Bang, Mugeun Lee, Jung-Ah Cho and Myungin Baek (Daegu, Korea - IJMS). The authors findings indicate that not only the species difference but also the microbiota play a significant role in wound healing in fish.

New scoring system for assessing wound healing - Eurekalert.org
Article by Mary Ann Liebert. Evaluating the efficacy of novel therapies requires the ability to monitor wound progression accurately and reproducibly over time. Researchers have proposed a new scoring system for wound healing in mice based on parameters in each phase of healing, as described in an article in the peer-reviewed journal Stem Cells and Development.

Temporary Storage of the Human Nasal Tissue and Cell Sheet for Wound Repair - Frontiersin.org
Article by Yoshiyuki Kasai, Tsunetaro Morino, Izumi Dobashi, Eri Mori, Kazuhisa Yamamoto and Hiromi Kojima (Tokyo, Japan - Front. Bioeng. Biotechnol.). The authors' results show that nasal tissues can be stored temporarily in refrigerators or deep freezers, and Hank’s balanced salt solution can be used for preservation of ready-to-use cell sheets for a few days.

Wound Bed Preparation Challenges - Woundsource.com
Wound bed preparation has been performed for decades in managing wounds of various etiologies. The wound healing process consists of a complex interlinked and independent cascade, which not all wounds follow in a consistent, organized manner. The TIMERS acronym, consisting of four general steps, has assisted clinicians globally to provide a systematic approach to wound bed preparation that includes Tissue debridement, Infection or Inflammation, Moisture balance, Edge effect, Regeneration and repair, and Social factors.

Cellular Mechanisms of FGF-Stimulated Tissue Repair - Mdpi.com
Article by Igor Prudovsky (Scarborough, USA - Cells). The author reviews the available literature on the enhancement of FGF expression and secretion in damaged tissues resulting in the increased FGF supply required for tissue repair.

Early and Intensive Glycemic Control for Diabetic Foot Ulcer Healing: A Prospective Observational Nested Cohort Study - PubMed
Abstract by Aditya Dutta, Anil Bhansali and Ashu Rastogi (Chandigarh, India - Int J Low Extrem Wounds).

Evaluation of Wound Healing Activity of Salvianolic Acid B on In Vitro Experimental Model - Mdpi.com
Article by Urszula Szwedowicz, Anna Szewczyk, Krzysztof Gołąb and Anna Choromańska (Wroclaw, Poland - IJMS). The results obtained in the conducted studies and previous scientific reports on the antibacterial properties and low toxicity of Sal B indicate its high potential in wound healing.

Editorial: Biomaterials for Skin Wound Repair: Tissue Engineering, Guided Regeneration, and Wound Scarring Prevention - Frontiersin.org
Article by Ubaldo Armato and Giuliano Freddi (China, Italy - Front. Bioeng. Biotechnol.). As the author keenly suggests, several social, economic, environmental, psychological determinants are known to interact with the biology of the individual and to determine health outcomes such as disease development, wound healing, and life expectancy. Thus, for an integrated approach to be successful, investments are needed in welfare, education, healthcare, and research, with a patient-centered view aimed at establishing an interdisciplinary environment able to address the still open challenges.

A new, inexpensive way to heal chronic wounds - Sciencedaily.com
Tens of millions of patients around the world suffer from persistent and potentially life-threatening wounds. These chronic wounds, which are also a leading cause of amputation, have treatments, but the cost of existing wound dressings can prevent them from reaching people in need. Now, a Michigan State University researcher is leading an international team of scientists to develop a low-cost, practical biopolymer dressing that helps heal these wounds.

Chemokine-Capturing Wound Contact Layer Rescues Dermal Healing - Wiley.com
Article by Lucas Schirmer, Passant Atallah, Uwe Freudenberg and Carsten Werner (Advanced Science). Beyond dermal wound healing, similar chemokine scavenging technologies using starPEG-GAG-based biohybrid polymer hydrogels are envisioned to create powerful new opportunities for therapeutic intervention in other diseases caused by or associated with excessive inflammation such as hypercytokinemia (“cytokine storm”), arthritis, inflammatory bowel disease, and several others.

Reparative and Maladaptive Inflammation in Tendon Healing - Frontiersin.org
Article by Varun Arvind and Alice H. Huang (New York, USA - Front. Bioeng. Biotechnol.). The authors highlight recent findings in this area, focusing on the cells and cytokines involved in reparative inflammation. They also discuss findings from other model systems when research in tendon is minimal, and explore recent studies in the treatment of human tendinopathy to glean further insights into the immunobiology of tendon healing.

Nanomaterials applied in wound healing: Mechanisms, limitations and perspectives - PubMed
Abstract by Menglei Wang, Xiaowen Huang, Huanxin Zheng, Yingmei Tang, Kang Zeng, Longquan Shao and Li Li (Guangzhou, China - J Control Release).

Wound Dressings for Hip and Knee Total Joint Arthroplasty: A Narrative Review - PubMed
Abstract by Christopher A Rothfusz, Ahmed K Emara, John P McLaughlin, Robert M Molloy, Viktor E Krebs and Nicolas S Piuzzi (Cleveland, USA - JBJS Rev.).

Chitosan/Hyaluronic acid/Alginate and an assorted polymers loaded with honey, plant, and marine compounds for progressive wound healing-Know-how - PubMed
Abstract by Murugan Prasathkumar and Subramaniam Sadhasivam (Coimbatore, India - Int J Biol Macromol.).

Hyaluronic Acid-Based Scaffolds as Potential Bioactive Wound Dressings - Mdpi.com
Article by Maria Teresa Climent Martí, Sergi Fernandez-Gonzalez, Maria Dolores Martí, Maria Jesus Pla, Marc Barahona and Jordi Ponce (Skin Health and Disease). Biopolymers offer interesting properties suitable for the design of wound dressings. This review article will be based on hyaluronic-acid-based scaffolds loaded with therapeutic agents for the treatment of wounds.

Prophylactic incisional negative pressure wound therapy for gynaecologic malignancies - Wiley.com
Article by Sibusiso Alven and Blessing A. Aderibigbe (Eastern Cape, South Africa - Polymers). The use of ciNPT to closure after laparotomy for gynaecological cancer is safe and effective for decreasing SSIs and median hospital stay. The findings of this study suggest clinical benefit with less rate of wound complications. Consequently, the application of ciNPT might be a cost-effective approach.

Come together: On-chip bioelectric wound closure - PubMed
Abstract by Tom J Zajdel, Gawoon Shim and Daniel J Cohen (Princeton, USA - Biosens Bioelectron).

Photobiomodulation Therapy in Burn Wound Healing: Systematic Review and Meta-Analysis of Preclinical Studies - PubMed
Abstract by Naira Figueiredo Deana, Nilton Alves, Carlos Zaror, Mariano Del Sol and Vanderlei Salvador Bagnato (Chile, Brazil - Photobiomodul Photomed Laser Surg.).

Potential Effects of Phenolic Compounds That Can Be Found in Olive Oil on Wound Healing - Mdpi.com
Article by Lucia Melguizo-Rodríguez, Elvira de Luna-Bertos, Javier Ramos-Torrecillas, Rebeca Illescas-Montesa, Victor Javier Costela-Ruiz and Olga García-Martínez (Granada, Spain - Foods). The authors' results indicate the potential usefulness of extra virgin olive oil phenolic compounds for wound treatment, either alone or in combination with other therapies. Human studies are warranted to verify this proposition.

HMP Global Announces Relaunch of ePlasty Digital Journal - Yahoo.com
As part of its continued mission to connect the global healthcare community with clinically relevant information and education that improves patient care, HMP Global, a leading healthcare event and education company, has announced the relaunch of ePlasty, the preeminent peer-reviewed digital journal dedicated to advancing medical and scientific knowledge in plastic and reconstructive surgery, surgical wound healing, vascular surgery, tissue repair, and more.

Wounds in chronic leg oedema - PubMed
Abstract by Ewa Anna Burian, Tonny Karlsmark, Susan Nørregaard, Klaus Kirketerp-Møller, Robert Scott Kirsner, Peter John Franks, Isabelle Quéré and Christine Joy Moffatt (Denmark, USA, UK, France - Int Wound J.).

Fever in a paraplegia patient with a pressure ulcer - PubMed
Abstract by Meheroz H Rabadi (Oklahoma City, USA - Radiol Case Rep.).

Outcomes and Characteristics of Wound Healing in an Outpatient Physical Therapy Clinic - PubMed
Abstract by Kehua Zhou, Leslie Frankish and Michael Ross (USA - Wounds).

Nanomaterials applied in wound healing: Mechanisms, limitations and perspectives - Sciencedirect.com
Abstract by Menglei Wang, Xiaowen Huang, Huanxin Zheng, Yingmei Tang, Kang Zeng, Longquan Shao and Li Li (Guangdong, China).

Natural-Based Biomaterial for Skin Wound Healing (Gelatin vs. Collagen): Expert Review - Mdpi.com
Article by Ruth Naomi, Hasnah Bahari, Pauzi Muhd Ridzuan and Fezah Othman (Malaysia - Polymers). This review compared Col and gelatin in terms of their structures, sources of derivatives, physicochemical properties, results of in vitro and in vivo studies, their roles in wound healing and the current challenges in wound healing. Thus, this review provides the current insights and the latest discoveries on both Col and gelatin in their wound healing mechanisms.

N-Acetylcysteine Added to Local Anesthesia Reduces Scar Area and Width in Early Wound Healing - An Animal Model Study - Mdpi.com
Article by Wiktor Paskal, Adriana M. Paskal, Piotr Pietruski, Albert Stachura, Kacper Pełka, Alan E. Woessner, Kyle P. Quinn, Michał Kopka, Ryszard Galus, Jarosław Wejman and Paweł Włodarski (Poland, USA - IJMS). N-acetylcysteine addition to pre-incisional anesthetic solution decreased wound size and width at an early stage of scar formation at all concentrations; however, with optimal results at 0.03% concentration.

Clinical Study of MEBO Combined with Jinhuang Powder for Diabetic Foot with Infection - Hindawi.com
Article by Hong-Bo Zhan Qing-Qing Sun Lei Yan and Jia Cai (Jingjiang, China - Evidence-Based Complementary and Alternative Medicine). Moist exposed burn ointment (MEBO) combined with Jinhuang powder is effective in treating diabetic foot with infection wound.

The outcome of natural honey used in chronic ulcers - Pharmascope.org
Article by Nizam Ahmed, Aftab Alam Khanzada, Muhammad Rafique Joyo, Tanveer Afzal, Niaz Hussain Keerio, Ghazanfar Ali Shah and Syed Shahid Noor. The leading causes of healing delays were bacterial infection, necrotic tissue involvement, bedridden state, age, fatigue, Ulcer located near the joint. The quality, the simplicity of application and the efficiency make the control of recurrent nonhealing Ulcers easier for natural honey.

Adipose mesenchymal stem cells combined with platelet-rich plasma accelerate diabetic wound healing by modulating the Notch pathway - Biomedcentral.com
Article by Nesrine Ebrahim, Arigue A. Dessouky, Ola Mostafa, Amira Hassouna, Mohamed M. Yousef, Yasmin Seleem, Eman Abd El Aziz M. El Gebaly, Mona M. Allam, Ayman Samir Farid, Bayan A. Saffaf, Dina Sabry, Ahmed Nawar, Ahmed A. Shoulah, Ahmed H. Khalil, Sami F. Abdalla, Mohamed El-Sherbiny, Nehal M. Elsherbiny and Rabab F. Salim (Egypt, New Zealand, Saudi Arabia - Stem Cell Research & Therapy). The authors' data demonstrated that platelet-rich plasma and adipose-derived mesenchymal stem cells combined therapy significantly accelerated healing of diabetic wounds induced experimentally in rats via modulating the Notch pathway, promoting angiogenesis and epidermal stem cells proliferation.

Peptides May Provide Key to Identifying Biomarkers for Healing, Infection - Ajmc.com
Article by Skylar Jeremias. Examination of surgical wound fluids revealed several peptides and proteins that could be useful in identifying biomarkers for wound healing and infection, potentially allowing providers to better diagnose and treat infections.

Rational Design of Immunomodulatory Hydrogels for Chronic Wound Healing - PubMed
Abstract by Mahshid Kharaziha, Avijit Baidya and Nasim Annabi (Iran, USA - Adv Mater.).

Hospital-Acquired Pressure Injuries and Acute Skin Failure in Critical Care: A Case-Control Study - PubMed
Abstract by Joyce Pittman, Terrie Beeson, Jill Dillon, Ziyi Yang, Michelle Mravec, Caeli Malloy and Janet Cuddigan (USA - J Wound Ostomy Continence Nurs.).

Clinical effects of high-intensity laser therapy on patients with chronic refractory wounds: a randomised controlled trial - Bmj.com
Article by Qian Lu, Zhifei Yin, Xuefeng Shen, Jinhua Li, Panpan Su, Min Feng, Xingjun Xu, Weiwei Li, Chuan He and Ying Shen (Suzhou, China). The therapeutic effects of high-intensity laser therapy (HILT) on chronic refractory wounds are significant and far more superior to those of conventional wound dressing.

Combating Infection With Smart Bandages - Technologynetworks.com
Article by Kate Robinson. External barriers such as the skin are the first line of defense against damage to internal structures. Upon injury, there is a complex, coordinated process that takes place to repair the wound, comprising four stages: hemostasis, inflammation, proliferation and remodeling. This process is vital to prevent colonization by pathogens.

In vitro and in vivo Effect of Platelet-Rich Plasma-Based Autologous Topical Serum on Cutaneous Wound Healing - PubMed
Article by Eduardo Anitua, Victoria Muñoz, Libe Aspe, Roberto Tierno, Adrian García-Salvador, Felipe Goñi-de-Cerio and Ander Pino (Spain - Skin Pharmacol Physiol.).

Effect of Complementary Medicine on Pain Relief and Wound Healing after Cesarean Section: A Systematic Review - PubMed
Abstract by Azin Niazi, Maryam Moradi, Vahid Reza Askari and Neda Sharifi (Mashhad, Iran - J Pharmacopuncture).

Are Semi-Quantitative Clinical Cultures Inadequate? Comparison to Quantitative Analysis of 1053 Bacterial Isolates from 350 Wounds - Mdpi.com
Article by Thomas E. Serena, Philip G. Bowler, Gregory S. Schultz, Anna D’souza and Monique Y. Rennie (USA, UK, Canada - Diagnostics). Since tissue biopsy and quantitative culture cannot be widely practiced and semi-quantitative analysis is unreliable, other clinically relevant approaches are required to determine wound bioburden and guide best management practices. Fluorescence imaging is a point-of-care technology that offers great potential in this field.

Anti-Sandwich Structured Photo-Electronic Wound Dressing for Highly Efficient Bacterial Infection Therapy - Wiley.com
Abstract by Kun Zhou, Dongdong Chigan, Letian Xu, Chenjing Liu, Rui Ding, Guoping Li, Zixi Zhang, Dandan Pei, Ang Li, Baolin Guo, Xuzhou Yan and Gang He (Nano-micro Small).

Pressure Ulcers, Stage 2 - Woundsource.com
Pressure ulcers are localized areas of tissue necrosis that typically develop when soft tissue is compressed between a bony prominence and an external surface for a long period of time. Stage 2 pressure ulcers are characterized by partial-thickness skin loss into but no deeper than the dermis. This includes intact or ruptured blisters.

Refractory Wounds: Systemic Factors Affecting Repair – Iatrogenic Factors (Part 3 of 4) - Woundsource.com
Article by Holly Hovan. In this blog, the author focuses on iatrogenic factors, or treatment-related factors, and how these impact healing.

Comorbidities May Delay Healing After Negative Pressure Wound Therapy in Head and Neck Cancer - Ajmc.com
Article by Skylar Jeremias. Despite positive data showing that negative pressure wound therapy (NPWT) can help accelerate wound healing for neck and head wounds, investigators of a review found that the presence of certain comorbidities may slow healing times.

Developing new techniques to build biomaterials - Sciencedaily.com
Scientists have developed an approach that could help in the design of a new generation of synthetic biomaterials made from proteins. The biomaterials could eventually have applications in joint repair or wound healing as well as other fields of healthcare and food production.

What Does It Mean to Cauterize a Wound? - Healthline.com
Cauterization, or cautery, is a medical technique performed by a doctor or surgeon. During the procedure, they use electricity or chemicals to burn tissue in order to close a wound. It may also be done to remove harmful tissue.

Use of Amniotic Tissue-Derived Allografts Post-Mohs Micrographic Surgery: A Preliminary Study Assessing Wound Closure Rate - PubMed
Abstract by Kayleen Seaton, Dustin Mullens, Jason Barr, Elizabeth Hull and Richard Averitte (Scottsdale, USA - Wounds).

Evidence Analyzing Infection Prevention Methods for Surgical Wounds Requires Definition Consensus - Ajmc.com
Artical by Skylar Jeremias. A lack of consensus for the term “immunocompromised” suggests that studies demonstrating the effectiveness of infection prevention in surgical patients at a high risk of wound infection may have limited relevancy.

Cellularized Skin Scaffold Treats Deep Thermal Burns - Hospimedica.com
A new skin graft for the treatment of deep partial-thickness thermal burns helps reduce the amount of autograft needed for future surgery.

The measurement properties of assessment tools for chronic wounds: A systematic review - PubMed
Abstract by Steven Smet, Sebastian Probst, Samantha Holloway, Anika Fourie, Hilde Beele and Dimitri Beeckman (Belgium, UK - Int J Nurs Stud.).

Wound Management of Multi-Site Pressure Ulcer at Different Stages in Elderly Patients - PubMed
Abstract by Shunqing Su, Xiumei Ding, Huijuan Zou, Yuechun Lin, Jianmin Huang, Disheng Xiong, Jinan Kuan, Yanhong Zhang and Rurong Xie (Dongguang, China - Clin Cosmet Investig Dermatol.).

The Role of MSC in Wound Healing, Scarring and Regeneration - Mdpi.com
Article by Raquel Guillamat-Prats (Badalona, Spain - Cells). This review describes the effects of mesenchymal stem/stromal cells (MSCs) and their derived products in each step of the wound repair process. As well, it reviews the pre-clinical and clinical use of MSCs to benefit in skin wound healing in diabetic associated wounds and in pathophysiological fibrosis.

Effect of Electrical Stimulation on Diabetic Human Skin Fibroblast Growth and the Secretion of Cytokines and Growth Factors Involved in Wound Healing - Mdpi.com
Article by Atieh Abedin-Do, Ze Zhang, Yvan Douville, Mireille Méthot and Mahmoud Rouabhia (Québec, Canada - Biology). The beneficial effect of electrical stimulation (ES) on fibroblast growth was maintained up to 5 days post-ES. Overall results suggest the possible use of low-intensity direct current ES to promote wound healing in diabetic patients.

Physical Activity as an Adjunct to Compression Therapy on Healing Outcomes and Recurrence in Patients With Venous Leg Ulcers: A Scoping Review Protocol - Frontiersin.org
Article by Yunjing Qiu, Christian Robert Osadnik, Victoria Team and Carolina Dragica Weller (Melbourne, Australia - Frontiers in Medicine). This scoping review protocol aims to systematically search, appraise, and synthesize quantitative research evidence to assess the effect of physical activity interventions applied in conjunction with compression therapy on venous leg ulcer healing and recurrence.

A new way to speed up wound healing in diabetic patients - Telanganatoday.com
A type of blood cells, called peripheral blood (PB) or bone marrow-derived endothelial progenitor cells (EPCs), contribute to the formation of blood vessels, and thus help in wound healing.

In new publication, 96% of clinicians state that treatment plans informed using the MolecuLight procedure led to improved wound healing - Biospace.com
Published results provides guidelines to standardize use of fluorescence imaging among wound care providers to enhance the quality of patient care.

The Combination of Stromal Vascular Fraction Cells and Platelet-Rich Plasma Reduces Malondialdehyde and Nitric Oxide Levels in Deep Dermal Burn Injury - Dovepress.com
Article by Fonny Josh, Tomie Hermawan Soekamto, Januar Rizky Adriani, Billy Jonatan, Hiroshi Mizuno and Muhammad Faruk (Indonesia, Japan - Journal of Inflammation Research). The combination of SVFs and PRP undeniably reduced the MDA and NO levels in blood and tissue compared to those in the Vaseline and placebo groups. The injection of these two preparations in combination inhibited the local and systemic stress oxidative response, as illustrated by the decreased MDA and NO levels in blood serum and tissue.

Scientists construct nano-scale borate bioactive glass with improved wound healing effects - News-medical.net
Recently, with the help of a steady-state strong magnetic field experimental device, scientists constructed nano-scale borate bioactive glass (Nano-HCA@BG), which can effectively reduce the biological toxicity of borate bioglass, improve the biocompatibility of the glass, and promote the effect of borate bioglass on skin repair.

A 3D skin infection model as an alternative to animal testing - Innovationorigins.com
At the UKJ Skin Clinic in Germany, scientists are working to develop skin infection models that will become an alternative to animal testing in the future to test new wound-healing products.

Chronic Wound Healing by Amniotic Membrane: TGF-β and EGF Signaling Modulation in Re-epithelialization - Frontiersin.org
Article by Catalina Ruiz-Cañada, Ángel Bernabé-García, Sergio Liarte, Mónica Rodríguez-Valiente and Francisco José Nicolás (Murcia, Spain - Front. Bioeng. Biotechnol.). The application of amniotic membrane (AM) on chronic wounds has proven very effective at resetting wound healing, particularly in re-epithelialization. Historically, several aspects of AM effect on wound healing have been evaluated using cell models.

Cutaneous Wound Healing: An Update from Physiopathology to Current Therapies - Mdpi.com
Article by Lucas Fernando Sérgio Gushiken, Fernando Pereira Beserra, Jairo Kenupp Bastos, Christopher John Jackson and Cláudia Helena Pellizzon (Brazil, Australia - Life). This work provides updated concepts of physiological mechanisms, the factors that can interfere, and updated treatments used in skin wound healing.

Resveratrol promotes skin wound healing by regulating the miR-212/CASP8 axis - Nature.com
Article by Yu Liu, Wu Xiong, Chu-Wang Wang, Jian-Ping Shi, Zhi-Qiang Shi and Jian-Da Zhou (China - Laboratory Investigation). The wound-healing process is a natural response to burn injury. Resveratrol (RES) may have potential as a therapy for wound healing, but how and whether RES regulates skin repair remains poorly understood. Human epidermal keratinocyte (HaCaT) cells were treated with lipopolysaccharide (LPS), and a mouse skin wound-healing model was established.

Wound Healing Activity of Extracts of Malva sylvestris and Stachys lavandulifolia - Ccsnet.org
Abstract by Abdollah Pirbalouti and Abed Koohpyeh.

Higher Periwound Temperature Associated with Wound Healing of Pressure Ulcers Detected by Infrared Thermography - PubMed
Abstract by Yen-Hsi Lin, Yen-Chin Chen, Kuo-Sheng Cheng, Po-Jui Yu, Jiun-Ling Wang and Nai-Ying Ko (Taiwan - J Clin Med.).

Wound dressings: curbing inflammation in chronic wound healing - PubMed
Abstract by Davide Vincenzo Verdolino, Helen A Thomason, Andrea Fotticchia and Sarah Cartmell (UK - Emerg Top Life Sci.).

Treatment of Wound Healing with Sequential Therapy to Accelerate Recovery and Inhibit Scar Hyperplasia: A Case Report - Dovepress.com
Article by Xiaoqing Li, Mei He and Hailun He (Chengdu, China - Clinical, Cosmetic and Investigational Dermatology). Clinically sequential therapy has demonstrated marked improvement in authors' case. Scar sequential therapy may offer a new strategy for wound healing recovery.

Improved hemocompatibility for gelatin-graphene oxide composite aerogels reinforced with proanthocyanidins for wound dressing applications - PubMed
Abstract by Jessica Borges-Vilches, Toribio Figueroa, Sebastián Guajardo, Claudio Aguayo and Katherina Fernández (Concepción, Chile - Colloids Surf B Biointerfaces).

The repetitive application of cold atmospheric plasma (CAP) improves microcirculation parameters in chronic wounds - PubMed
Abstract by Jan-Oluf Jensen, Lysann Schulz, Sophie Schleusser, Nico Matzkeit, Felix H Stang, Peter Mailaender, Robert Kraemer, Markus Kleemann, Henriette Deichmann and Tobias Kisch (Germany - Microvasc Res.).

Consensus on the application of negative pressure wound therapy of diabetic foot wounds - PubMed
Abstract by Shizhao Ji, Xiaobin Liu, Jie Huang, Junmin Bao, Zhaohong Chen, Chunmao Han, Daifeng Hao, Jingsong Hong, Dahai Hu, Yufeng Jiang, Shang Ju, Hongye Li, Zongyu Li, Guangping Liang, Yan Liu, Gaoxing Luo, Guozhong Lv, Xingwu Ran, Zhongmin Shi, Juyu Tang, Aiping Wang, Guangyi Wang, Jiangning Wang, Xin Wang, Bing Wen, Jun Wu, Hailin Xu, Maojin Xu, Xiaofei Ye, Liangxi Yuan, Yi Zhang, Shichu Xiao and Zhaofan Xia (China - Burns Trauma).

Effect of negative pressure wound therapy for legs in complex wound diabetic patients: Therapeutic challenge and review - PubMed
Abstract by Túlio Fabiano de Oliveira Leite, Elpidio Ribeiro da Silva and Edwaldo Edner Joviliano (Ribeirão Preto, Brazil - SAGE Open Med Case Rep.).

Epidemiology, Pathophysiology, and Management Strategies of Neonatal Wound Care - PubMed
Abstract by Yomna Amer, Catherine Bridges and Kalyani Marathe (USA - Neoreviews).

Lymphedema / Phlebolymphedema - Woundsource.com
Lymphedema is a condition marked by the retention of interstitial fluid (lymph) and the swelling (edema) of surrounding soft tissue, often affecting the extremities. It is also referred to as lymphatic obstruction. The lymphatic system is responsible for carrying interstitial fluid originating from the blood to the right lymphatic duct and the thoracic duct, also known as the left lymphatic duct, and then back into the bloodstream.

Global Malnutrition Composite Score Addresses Gap in Care - Woundsource.com
Articly by Catherine D’Andrea and Marcia Nusgart. Malnutrition is a leading cause of morbidity and mortality, especially among older hospitalized adults, yet it often goes undiagnosed and therefore untreated. It has been established that malnourished hospitalized patients experience slower wound healing, higher risks of infection, and longer length of stay. Malnutrition is a burdensome condition associated with a 34% higher cost for a hospital stay compared with a non-malnourished patient.

Restructuring of the plasma membrane upon damage by LC3-associated macropinocytosis - Sciencemag.org
Articly by Stine Lauritzen Sønder, Swantje Christin Häger, Anne Sofie Busk Heitmann, Lisa B. Frankel, Catarina Dias, Adam Cohen Simonsen and Jesper Nylandsted (Denmark - Cell Biology). The plasma membrane shapes and protects the eukaryotic cell from its surroundings and is crucial for cell life. Although initial repair mechanisms to reseal injured membranes are well established, less is known about how cells restructure damaged membranes in the aftermath to restore homeostasis.

Naturally-derived targeted therapy for wound healing: Beyond classical strategies - PubMed
Abstract by Saeed El Ashram, Lamia M El-Samad, Amal A Basha and Abeer El Wakil (Egypt - Pharmacol Res.).

The stability and irritability study of the chitosan- Aloe vera spray gel as wound healing - PubMed
Abstract by Dini Retnowati, Retno Sari, Esti Hendradi and Septiani Septiani (Surabaya, Indonesia - J Basic Clin Physiol Pharmacol.).

Tranexamic Acid May Promote Wound Healing by Reducing Blood Loss, Study Suggests - Ajmc.com
Article by Skylar Jeremias. Topical and intravenous tranexamic acid were found to significantly reduce blood loss compared with placebo in patients who have undergone bone surgery, suggesting that both administration methods may be effective at promoting wound healing.

Oncologic feasibility for negative pressure wound therapy application in surgical wounds: A meta-analysis - PubMed
Abstract by Yen-Jen Wang, Xiao-Feng Yao, Yang-Sheng Lin, Jen-Yu Wang and Chang-Cheng Chang (Taipei, Taiwan - Int Wound J.).

Preparation and Application of Quaternized Chitosan- and AgNPs-Base Synergistic Antibacterial Hydrogel for Burn Wound Healing - Mdpi.com
Article by Xushan Chen, Huimin Zhang, Xin Yang, Wuhong Zhang, Ming Jiang, Ting Wen, Jie Wang, Rui Guo and Hanjiao Liu (China - Molecules). The hydrogel, composed of nature biomaterials, has a good cytocompatibility and biodegradability. Moreover, the hydrogel has an excellent antibacterial ability and presents fast healing for burn wounds compared with commercial Ag dressings.

Vitamin E: A Review of Its Application and Methods of Detection When Combined with Implant Biomaterials - Mdpi.com
Article by Francesca Gamna and Silvia Spriano (Torino, Italy - Materials). This review specifically aims to compile research about new biomedical applications of vitamin E carried out in the last 20 years, with the intention of providing an overview of the methodologies used to combine it with implantable biomaterials, as well as to detect and characterize it within these materials.

Roles and mechanisms of stem cell in wound healing - Amegroups.com
Article by Thurga Ayavoo, Karthikeyan Murugesan and Ashok Gnanasekaran (Perak, Malaysia - Stem Cell Investigation). This review focuses on the pre-existing traditional and modern treatments for wound healing, and types and roles of stem cells in wound care management. This review also focuses on the fundamental molecular characterization and factors influencing the molecular mechanisms of stem cells in wound healing.

Bacterial cellulose an effective material in the treatment of chronic venous ulcers of the lower limbs - PubMed
Abstract by Liliada G Silva, Amanda V Albuquerque, Flávia C M Pinto, Rafaela S Ferraz-Carvalho, José L A Aguiar and Esdras M Lins (Recife, Brazil - J Mater Sci Mater Med.).

Flexible Ultrasonic Patch for Accelerating Chronic Wound Healing - Wiley.com
Abstract by Wenhan Lyu, Yinji Ma, Siyu Chen, Haibo Li, Peng Wang, Ying Chen and Xue Feng (Advanced Healthcare Material).

Therapeutic Potential of Luteolin on Impaired Wound Healing in Streptozotocin-Induced Rats - Mdpi.com
Article by Li-You Chen, Hsin-Lin Cheng, Yu-Hsiang Kuan, Tang-Jun Liang, Yun-Yi Chao and Hsing-Chun Lin (Taichung, Taiwan - Biomedicines). Systemic administration of luteolin promotes wound restoration by ameliorating inflammation and oxidative stress through the inactivation of NF-κB and upregulation of Nrf2 in STZ-induced diabetic rats.

Procoagulant and Antimicrobial Effects of Chitosan in Wound Healing - Mdpi.com
Article by Chih-Hsin Wang, Juin-Hong Cherng, Chuan-Chieh Liu, Tong-Jing Fang, Zhi-Jie Hong, Shu-Jen Chang, Gang-Yi Fan and Sheng-Der Hsu (Taipei, Taiwan - IJMS). The authors' findings suggest that chitosan dressing is an effective antimicrobial and procoagulant and promotes wound repair by providing a suitable environment for beneficial microbiota.

Thermal imaging techniques can predict healing of venous leg ulcers - Medical.net
New research shows thermal imaging techniques can predict whether a wound needs extra management, offering an early alert system to improve chronic wound care.

The effect of botulinum toxin injection dose on the appearance of surgical scar - Nature.com
Article by Zhiyou Chen, Zong Chen, Ran Pang, Zhiru Wei, Han Zhang, Wenhui Liu and Guangshuai Li (Zhengzhou, China - Scientific Reports). The purpose of this study was to investigate the effect of different doses of BTxA administered early after surgery on scar improvement through a split-scar experiment.

Unilateral Silver-Loaded Silk Fibroin Difunctional Membranes as Antibacterial Wound Dressings - Acs.org
Article by Jinlong Shao, Yating Cui, Ye Liang, Hong Liu, Baojin Ma and Shaohua Ge (Jinan, China - ACS Omega). Unilateral loading with the simplified layer-by-layer preparation technique provided an effective method to balance the cytotoxicity and the antibacterial property of Ag-loaded materials and thus form a broader therapeutic window for Ag applications. The unilateral Ag-loaded silk fibroin difunctional membranes have the potential to be further preclinically explored as wound dressings.

Adipose Tissue-Derived Mesenchymal Stem Cells (ADMSCs) and ADMSC-Derived Secretome Expedited Wound Healing in a Rodent Model – A Preliminary Study - Dovepress.com
Article by Hui Ma, Ping Kuen Lam, Wing Sum Siu, Cindy See Wai Tong, Kin Ki Yan Lo, Chi Man Koon, Xiao Xiao Wu, Xiang Li, Wen Cheng, Wai Ting Shum and Ping Chung Leung (Hong Kong - Clinical, Cosmetic and Investigational Dermatology). The authors' study indicated both MSCs and MSCs-derived secretome enhanced the wound healing process in early phase. Secretome further promoted the healing effects through promoting the fibroblast proliferation and migration and suppressing the inflammatory response.

Biologic Graft Augmentation of Anterior Mesh Erosion Complicated by Poor Wound Healing Secondary to Heavy Tobacco Use - Mdpi.com
Article by Cheau Williams, Ethan McBrayer and Samantha Leggio (USA - Uro). This case illustrates that complicated transvaginal mesh erosion should initially be augmented with a biologic dermal graft secured via sacrospinous ligament/arcus tendineus fascia pelvis fixation and double-layer closure and not only if visible mesh removal alone fails.

Anti-diabetic and wound healing potential of Benincasa hispida in streptozotocin-induced diabetic rats - Pharmascope.org
Article by Vemulapalli Ravi Kumar, Veerachamy Alagarsamy and Rakesh Kumar Jat (India - International Journal of Research in Pharmaceutical Sciences). B. hispida showed a significant antidiabetic and wound activities mediated through its antioxidant effect.

Application of Fish Collagen-Nanochitosan-Henna Extract Composites for the Control of Skin Pathogens and Accelerating Wound Healing - Hindawi.com
Article by Ahmed A. Tayel, Reem A. Ghanem, Mohammed S. Al-Saggaf, Dalia Elebeedy and Ahmed I. Abd El Maksoud (Egypt, Saudi Arabia - International Journal of Polymer Science). The natural NCht/He/Cg composites are recommended as topical applications for optimum skin disinfection and regeneration.