Wound healing by transplantation of mesenchymal stromal cells loaded on polyethylene terephthalate scaffold: Implications for skin injury treatment - Sciencedirect.com
Article by Betzabeth Pereira , Kharelys Duque, Giselle Ramos-Gonzalez, Dylana Díaz-Solano, Olga Wittig, Mariela Zamora, Teresa Gledhill and José E. Cardier (Caracas, Venezuela - Injury).
The authors' results show that MSCs/PET implants induce a rapid re-epithelialization of deep- and full-thickness wounds. MSCs/PET implants constitute a potential clinical therapy for treating cutaneous wounds.
The Role of Extracellular Matrix in Wound Healing - PubMed
Abstract by Pingping Lin, Guohong Zhang and Hang Li (China - Dermatol Surg.).
The Effects of Vitamin C on Wound Healing – Systematic Review - Springer.com
Abstract by Thanigasalam Thevi, Adinegara Lutfi Abas and Mohan Rajan (Malaysia, India - Indian Journal of Surgery).
Effect of cold atmospheric plasma therapy on wound healing in patients with diabetic foot ulcers: protocol for a systematic review and meta-analysis - Bmj.com
Article by Zinan Li, Qian Zhou, Jiao Yang, Xianliang Qiu, Shunlian Fu and Qiu Chen (Chengdu, China - BMJ).
The results of this research will present a scientific basis for the treatment of diabetic foot with CAP therapy. Bias and significant heterogeneity could emerge as the investigation progresses; therefore, authors will conduct subgroup analysis and sensitivity analysis where appropriate to explore the sources of heterogeneity as much as possible and ensure the reliability of the results.
Recent Advances in Collagen Antimicrobial Biomaterials for Tissue Engineering Applications: A Review - Mdpi.com
Article by Caglar Ersanli, Athina Tzora, Ioannis Skoufos, Chrysoula (Chrysa) Voidarou and Dimitrios I. Zeugolis (Greece, Ireland - IJMS).
In this study, authors reviewed the different approaches used to develop collagen-based antimicrobial devices, such as non-pharmacological, antibiotic, metal oxide, antimicrobial peptide, herbal extract-based, and combination approaches, with a particular focus on preclinical studies that have been published in the last decade.
Predictors of hospital-acquired pressure injuries in patients with complete spinal cord injury: a retrospective case-control study - PubMed
Abstract by Phumeena Balasuberamaniam, Abeer Wasim, Mopina Shrikumar, Tan Chen et al. (Canada, USA - BMC Musculoskelet Disord.).
Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing - Biomedcentral.com
Article by Chuchao Zhou, Boyu Zhang, Yanqing Yang, Qiong Jiang, Tianyu Li, Jun Gong, Hongbo Tang and Qi Zhang (Wuhan, China - Stem Cell Research & Therapy).
This study focuses on the specific roles and mechanisms of different MSC-exos in wound healing, as well as the current limitations and various perspectives.
The Role of Cold Atmospheric Plasma in Wound Healing Processes in Critically Ill Patients - Mdpi.com
Article by Tatiana Bolgeo, Antonio Maconi, Menada Gardalini, Denise Gatti, Roberta Di Matteo, Marco Lapidari, Yaroslava Longhitano, Gabriele Savioli, Andrea Piccioni and Christian Zanza (Italy, USA - JPM).
Cold atmospheric plasma is effective in many areas of the medical field, with no significant adverse effects on healthy cells.
Study evaluates the effects of phenolic compounds in extra virgin olive oil on skin health - News-medical.net
Article by Tarun Sai.
A recent study published in the Nutrients Journal evaluated the effects of phenolic compounds in extra virgin olive oil on the proliferation, cell cycle, migration, and antigenic profile of human fibroblasts.
Stretching Promotes Wound Contraction Through Enhanced Expression of Endothelin Receptor B and TRPC3 in Fibroblasts - Lww.com
Article by Kenichiro Kawai, Hisako Ishise, Tateki Kubo, Barrett Larson, Toshihiro Fujiwara, Soh Nishimoto and Masao Kakibuchi (Japan, USA - Plastic & Reconstructive Surgery-Global Open).
The authors' findings suggest that cyclical stretching of wounds have an effect on both keratinocytes and fibroblasts, where keratinocytes secret more ET-1, and fibroblasts develop more sensitivity to ET-1 by expressing more endothelin receptors and TRPC3.
Tissue Granulation in Cutaneous Wound Healing is Improved by a Camel Milk Peptide in Streptozotocin-induced Diabetes in Rat Models - Arccjournal.com
Article by H. Ebaid, J. Al-Tamimi, I.M. Alhazza and A. Metwalli (Riyadh, Saudi Arabia - Indian Journal of Animal Research).
The authors' data confirmed the potential role of CMP in wound healing in diabetic rats.
Effect of supplements/intensive nutrition on pressure ulcer healing: a multicentre, randomised controlled study - PubMed
Abstract by Merrilyn D Banks, Joan Webster, Judy Bauer, Kathleen Dwyer, Anita Pelecanos et al. (Australia - J Wound Care).
Skin wound healing as a mirror to cardiac wound healing - Wiley.com
Article by Merry L. Lindsey and Mediha Becirovic-Agic (USA, Sweden - Experimental Physiology).
The authors highlight differences and similarities between skin and cardiac wound healing and summarize how skin can be used to provide information about the heart.
Robust classification of wound healing stages in both mice and humans for acute and burn wounds based on transcriptomic data - Biomedcentral.com
Article by Ksenia Zlobina, Eric Malekos, Han Chen and Marcella Gomez (Santa Cruz, USA - BMC Bioinformatics).
In this work, auhors present an algorithm for wound stage detection based on gene expression. This work suggests that there are universal characteristics of gene expression in wound healing stages despite the seeming disparities across species and wounds.
Wound balance: Achieving wound healing with confidence - Woundsinternational. com
Article by Alison Garten, Hans Smola, Christine Blome, Michele Carr, Florian Dumas, John Schäfer, Sharon Trouth, Magali Veiga Marques, Lesa G. Williams, Zena Moore and Harikrishna KR Nair (USA, Germany, UK - Wounds).
This document provides guidance in achieving ‘wound balance’, and specifically how this can be applied to practice to improve outcomes.
Pseudomonas Wound Infection: What Is It and What Are the Signs? - Woundsource.com
Article by Emily Greenstein.
Pseudomonas aeruginosa (PA) is a common gram-negative aerobic bacilli bacterial infection in chronic wounds. PA is an opportunistic infection that can cause serious disease. Patients with an immunocompromised state will often have PA infections.
Beyond Medications: Exploring Virtual Reality's Role in Non-Pharmacological Pain Management for Wound Care - Woundsource.com
Article by Thanoon Thabet.
Pain is an important factor when performing wound care procedures like dressing changes, which account for moderate to severe pain in 74% of wound care patients. A current, non-pharmacological pain management approach emerging as a promising alternative is virtual reality.
Preclinical Assessment of Novel Longer-Duration Wear Negative Pressure Wound Therapy Dressing in a Porcine Model - PubMed
Abstract by Diwi Allen, Timothy Robinson, Marisa Schmidt and Kristine Kieswetter (USA - Wound Repair Regen.).
Prehabilitation: Preventing Operative Complications in Reconstructive Plastic Surgery Patients - Woundsource.com
Surgical site infections (SSIs) are just one of the many complications that may follow a surgical procedure. A study conducted from 2019-2020 found the rate of SSIs in Medicare and Premier populations to be 2%, with the rate of SSIs in patients who received abdominal surgery at approximately 5%.
Closure of pressure injury and mortality in internal medicine wards - PubMed
Abstract by Pinar Gurun, Serdar Ceylan, Merve Guner, Arzu Okyar Bas and Meltem Gulhan Halil (Ankara, Turkey - Eur Geriatr Med.).
Tissue Adhesive, Biocompatible, Antioxidant, and Antibacterial Hydrogels Based on Tannic Acid and Fungal-Derived Carboxymethyl Chitosan for Wound-Dressing Applications - Mdpi.com
Article by Kummara Madhusudana Rao, Uluvangada Thammaiah Uthappa, Hyeon Jin Kim and Sung Soo Han (Gyeongbuk, Korea - Gels).
The developed drug-free antibacterial and tissue-adhesive hydrogels can potentially be used as wound dressings for infected wounds.
Relaxation Intervention to Improve Diabetic Foot Ulcer Healing: Results from a Pilot Randomized Controlled Study - PubMed
Abstract by Gabriela Ferreira, Susana Faria, André Carvalho and M Graça Pereira (Portugal - Wound Repair Regen.).
Severe Pressure Ulcers in Two Patients With Adrenoleukodystrophy - PubMed
Abstract by Koji Obara (Yurihonjo, Japan - Cureus).
Distal memory in wound healing and cancer - Nature.com
Abstract by Frank Lyko (Heidelberg, Germany - Nature Cell Biology).
Sternal Wound Management in Pediatric Cardiac Surgical Patients: A Novel Strategic Interprofessional Approach - PubMed
Abstract by Neerod Kumar Jha, Muhammad Shafique, Raisy Thomas, Salvacion Pangilinan Cruz, Gulnaz Tariq and Laszlo Kiraly (Abu Dhabi, United Arab Emirates - Adv Skin Wound Care).
Surgical Reconstruction of Stage 3 and 4 Pressure Injuries: A Literature Review and Proposed Algorithm from an Interprofessional Working Group - PubMed
Abstract by Samir S Awad, James D Stern, Cathy T Milne, Shane G Dowling, Ron Sotomayor, Elizabeth A Ayello et al. (USA, New Zealand - Adv Skin Wound Care).
Researching the level of agreement among experts on terms used to describe wounds: An international study - Wiley.com
Article by Alessandro Greco, Diego Mastronicola, Francesco Pacini, Luca Giacomelli, Simonetta Papa, Chiara Fiorentini, Valentina David, Sara Rowan, Natascia Mennini and Cristina Magnoni (International Wound Journal).
Establishing a common language that allows univocal and objective communication in describing wounds and their healing is of utmost importance in defining the diagnostic hypothesis and proper wound management. To measure the level of agreement on the description of wounds, an international study was performed among experts of different professional backgrounds on several common terms used to describe ulcerative lesions.
Esophageal wound healing by aligned smooth muscle cell-laden nanofibrous patch - Sciencedirect.com
Article by Miji Yeo, Jung Won Yoon, Gyu Tae Park, Sung-Chan Shin, Young-Cheol Song, Yong-Il Cheon, Byung-Joo Lee, Geun Hyung Kim and Jae Ho Kim (Korea, USA - Materials Today Bio).
Cell electrospinning with its advantages, such as guidance of highly elongated, aligned cell morphology and accelerated smooth muscle cells differentiation, can be an efficient strategy to reconstruct smooth muscle tissues and treat esophageal perforation.
Qualitative study on diabetic cutaneous wound healing with radiation crosslinked bilayer collagen scaffold in rat model - Nature.com
Article by Hongwei Li, Xin Chen, Kang Ren, Lihao Wu, Gong Chen and Ling Xu (China - Scientific Reports).
The work expands the therapeutic ideas for cutaneous wound healing in diabetes.
The Role of Physical Therapies in Wound Healing and Assisted Scarring - Mdpi.com
Article by Montserrat Fernández-Guarino, Stefano Bacci, Luis Alfonso Pérez González, Mariano Bermejo-Martínez, Almudena Cecilia-Matilla and Maria Luisa Hernández-Bule (Spain, Italy - IJMS).
This review aims to summarize the role of physical therapies as complementary treatments in WH and scarring. The article proposes a translational view, opening the opportunity to develop these therapies in an optimal way in clinical management, as many of them are emerging. The role of laser, photobiomodulation, photodynamic therapy, electrical stimulation, ultrasound therapy, and others are highlighted in a practical and comprehensive approach.
The effects of mechanical force on fibroblast behavior in cutaneous injury - Frontiersin.org
Article by Charlotte E. Berry, Mauricio Downer Jr, Annah G. Morgan, Michelle Griffin, Norah E. Liang, Lionel Kameni, Jennifer B. Laufey Parker, Jason Guo, Michael T. Longaker and Derrick C. Wan (Stanford, USA - Front. Surg.).
Using a variety of inventive in vitro and in vivo models, scientists have demonstrated the importance of the fibroblast as a critical cell in mechanosensitivity and mechanoresponsiveness. Several proteins, transcriptional cofactors, and signaling pathways, have been characterized in connection to mechanotransduction in cutaneous injury, and novel technologies in cellular biology have allowed for more granular understanding of these interactions and fibroblast behavior in response to mechanical stress than ever before.
The applications of 3D printing in wound healing: the external delivery of stem cells and antibiosis - Frontiersin.org
Abstract by Qingtong Yu, Qilong Wang, Linzhi Zhang, Wenwen Deng, Xia Cao, Zhe Wang, Xuan Sun, Jiangnan Yu and Ximing Xu (Zhenjiang, China - Adv Drug Deliv Rev.).
Computational modeling and simulation of epithelial wound closure - Nature.com
Article by Jie Bai and Xiaowei Zeng (San Antonio, USA - Scientific Reports).
The model presented in this study can be employed as a numerical tool to unravel the mechanical principles behind the complex wound closure process. These results might have the potential to improve effective wound management and optimize the treatment.
Release systems based on self-assembling RADA16-I hydrogels with a signal sequence which improves wound healing processes - Nature.com
Article by Maria Dzierżyńska, Justyna Sawicka, Milena Deptuła, Paweł Sosnowski, Piotr Sass, Barbara Peplińska, Zuzanna Pietralik-Molińska, Martyna Fularczyk et al. (Poland - Scientific Reports).
Improved wound healing following topical delivery of RADA-GHK and RADA-KGHK was demonstrated using a model of dorsal skin injury in mice and histological analyses. The presented results indicate further research is warranted into the engineered peptides as scaffolds for wound healing and tissue engineering.
How electricity can heal wounds three times as fast - Sciencedaily.com
Chronic wounds are a major health problem for diabetic patients and the elderly -- in extreme cases they can even lead to amputation. Using electric stimulation, researchers have developed a method that speeds up the healing process, making wounds heal three times faster.
Timely Wound Care: The Birth of the Triage System - Woundsource.com
Article by Christine Miller.
A French surgeon recommended immediate surgical intervention for traumatic wounds, including debridement (removal of devitalized tissue) and amputation (for severe injuries), which resulted in better survival rates. Debridement continues to be widely performed in the field of wound management.
Lymphedema and Lipedema: Different Conditions With Similar Obstacles - Woundsource.com
In this interview, WoundCon speaker Brandy Mckeown shares her insights on new innovations and practical knowledge regarding the treatment of lymphedema and lipedema.
Uncommon Wounds: How Online Health Communities Can Help - Woundsource.com
Article by Scott Bolhack.
The author shares insights he gained from the uncommon wound he encountered. Learn how, with his co-author, he discovered the best course of action for this delayed histamine reaction to a stingray injury and how it can be applied to the management of other uncommon wounds.
Natural polymers in wound healing: From academic studies to commercial products - Wiley.com
Article by Mohamadreza Tavakoli, Sheyda Labbaf, Marjan Mirhaj, Saeideh Salehi, Alexander Marcus Seifalian and Mahboubeh Firuzeh (Iran, UK - Journal of Applied Polymer Science).
The outcome was chitosan (CS), as a carbohydrate, has the most clinical application as it is readily available and affordable, and has shown excellent antibacterial activity. Among proteins, keratin (Kr) can be an option with similar characteristics, however, Kr has not yet found clinical use when compared with CS.
Skin Pigmentation Impacts the Clinical Diagnosis of Wound Infection: Imaging of Bacterial Burden to Overcome Diagnostic Limitations - Springer.com
Article by Jonathan Johnson, Alton R. Johnson Jr., Charles A. Andersen, Martha R. Kelso, Alisha R. Oropallo and Thomas E. Serena (USA - Journal of Racial and Ethnic Health Disparities).
The authors' findings underscore the threat of pervasive racialized health inequities in wound care, where missed diagnosis of pathogenic bacteria and infection could delay treatment, increasing the risk of complications and poor outcomes.
Hyperbaric Oxygen Therapy Reduces Oxidative Stress and Inflammation, and Increases Growth Factors Favouring the Healing Process of Diabetic Wounds - Mdpi.com
Article by Xavier Capó, Margalida Monserrat-Mesquida, Magdalena Quetglas-Llabrés, Juan M. Batle, Josep A. Tur, Antoni Pons, Antoni Sureda and Silvia Tejada (Spain - IJMS).
HBOT reduced oxidative and pro-inflammatory mediators, and may participate in activating healing, angiogenesis and vascular tone regulation by increasing the release of growth factors.
Getting to the Root of Skin Healing - The-scientist.com
Article by Iris Kulbatski.
In a recent study published in npj Regenerative Medicine, Claire Higgins, a professor of bioengineering at Imperial College London, and her team performed a pilot clinical study in which they transplanted hair follicles into human skin scars. The team decided to take a deeper look below the skin’s surface to understand how follicle transplants change the architecture of scarred skin tissue.
Therapeutic Strategies For Treatment of Chronic Wounds - Iccliniq.com
Article by Lincy Varghese.
Chronic wounds are the type of wound that fails to improve that passes through the normal stage of wound healing.
Digital Twin in Chronic Wound Management - Springer.com
Abstract by Salih Sarp, Murat Kuzlu, Yanxiao Zhao, Ferhat Ozgur Catak, Umit Cali, Vukica Jovanovic and Ozgur Guler (USA, Norway).
A fabric-based wearable sensor for continuous monitoring of decubitus ulcer of subjects lying on a bed - PubMed
Abstract by Soyeon Lee, Seung-Rok Kim, Kun-Hoo Jeon, Jun-Woo Jeon, Ey-In Lee, Jiwan Jeon, Je-Heon Oh, Ju-Hyun Yoo, Hye-Jun Kil and Jin-Woo Park (Korea - Sci Rep.)
Pressure injury susceptibility related to lifestyle factors in patients with spinal cord injury: a cross-sectional survey - PubMed
Abstract by Dronacharya Gyawali and Niraj Singh Tharu (Dhaka, Bangladesh - J Wound Care).
Use of negative pressure wound therapy on locoregional flaps: a case-control study - PubMed
Abstract by Kong Yuan, Alison Quah, Jolie Hwee, Roland Xu, Wu Yijun, Ng Hui Wen and Pek Chong Han (Singapore - J Wound Care).
Speeding Healing by 30%: The First Transient Electronic Bandage - Scitechdaily.com
Northwestern University scientists have created a first-of-its-kind small, flexible, stretchable bandage that hastens the healing process by administering electrotherapy directly to the injury. In a trial on animals, the innovative bandage was found to heal diabetic sores 30% quicker in mice compared to those without the bandage.
Promoted Skin Wound Healing by Tail-Amputated Eisenia foetida Proteins via the Ras/Raf/MEK/ERK Signaling Pathway - Acs.org
Article by Tianyi Li, Yujie Sun, Jiaqi Wang, Chenning Zhang and Yikun Sun (Beijing, China - ACS Omega).
The tail-amputated E. foetida proteins (ES2) can significantly promote skin wound healing better than the un-amputated earthworm tissue extract without excessive scar tissue formation. This effect was related to the up-regulation of the Ras/Raf/MEK/ERK signaling pathway.
Red Light Therapy: Benefits, Side Effects And Uses - Forbes.com
Article by Kimberly Dawn Neumann and Jessica Cho.
Red light therapy may be beneficial when it comes to improved skin appearance, wound healing and pain management, according to current research.
A hydrogel wound dressing ideally designed for chronic wound care - Sciencedirect.com
Abstract by Yang Li, Daifeng Hao, Guang Feng and Fu-jian Xu (Beijing, China - Matter).
Early Skin Temperature Characteristics of the Kennedy Lesion (Kennedy Terminal Ulcer) - PubMed
Abstract by Karen Lou Kennedy-Evans, Deanna Vargo, Leslie Ritter, Diane Adams, Suzanne Koerner and Ellen Duell (USA - Wound Manag Prev.).
A systematic review of medical science students' knowledge and related factors towards burns first aids - PubMed
Abstract by Hamidreza Alizadeh Otaghvar, Arman Parvizi, Pooyan Ghorbani Vajargah, Amirabbas Mollaei, Samad Karkhah, Poorya Takasi, Seyed Javad Hosseini et al. (Iran - Int Wound J.).
Pressure Injury Prevention in Patients in Prone Position With Acute Respiratory Distress Syndrome and COVID-19 - PubMed
Abstract by Julia Ruhland, Enrico Dähnert, Max Zilezinski and Armin Hauss (Berlin, Germany - Crit Care Nurse).
Electrospinning Nanofibers as a Dressing to Treat Diabetic Wounds - Mdpi.com
Article by Eun Jo Jang, Rajkumar Patel and Madhumita Patel (Korea - Pharmaceutics).
In this review, the authors discuss several polymers used to create nanofiber membranes and their effectiveness in the treatment of diabetic wounds.
Basal Cell Carcinoma Arising From a Nonhealing Lower Extremity Ulcer: A Case Report - Hmpgloballearningnetwork.com
Article by Sidra Deen, Usman Asad and Edward Lee Poythress (Houston, USA - Wounds).
This case highlights the importance of prompt biopsy and cultures in patients with suspicious ulcers and wounds that do not respond to appropriate treatment.
Noninfectious Skin Fistulization as a Delayed Complication of Lumbar Interlaminar Device Implantation: A Report of Two Cases - Hmpgloballearningnetwork.com
Article by Keyvan Mostofi and Morad Peyravi (France, Germany - Wounds).
These 2 cases of delayed noninfectious fistulization following instrumented spine surgery are the first seen by the authors of the current report, and as of the time of this writing, no such cases have been documented in the medical literature.
Pentoxifylline/Chitosan Films on Wound Healing: In Vitro/In Vivo Evaluation - Mdpi.com
Article by Vandiara Martins Moreira, Joandra Maísa da Silva Leite, Kaline de Araújo Medeiros, Karoll Moangella Andrade de Assis, Joyce Cordeiro Borges, Lucas Matheus Barreto Santana et al. (Campina Grande, Brazil - Pharmaceutics).
The combination of chitosan and pentoxifylline is effective in their formation and incorporation, demonstrating that a higher concentration of pentoxifylline accelerates skin-wound reduction.
Fibrous dressing containing bioactive glass with combined chemotherapy and wound healing promotion for post-surgical treatment of melanoma - PubMed
Abstract by Caini Yuan, Daixing Zhang, Yujing Tang, Zifang Guo, Kai Lin, Yingjie Yu, Jinghua Li and Qing Cai (Beijing, China - Biomater Adv.).
Understanding the Basics of Street Medicine and Wound Care - Woundsource.com
Article by Laura Swoboda.
Even when delivering office-based medical care, we know that 80% of outcomes aren’t due to the care we, as clinicians, provide. Instead, these outcomes are related to our patients' environment and social conditions. These factors are collectively known as social determinants of health (SDOH).
Offloading devices for the prevention of heel pressure ulcers: A realist evaluation - PubMed
Abstract by Clare Greenwood, Jane Nixon, E Andrea Nelson, Elizabeth McGinnis and Rebecca Randell (UK - Int J Nurs Stud.).
Efficacy of Strategies Intended to Prevent Surgical Site Infection After Lower Limb Revascularization Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials - PubMed
Abstract by Aidan M Kirkham, Jasmine Candeliere, Daniel I McIsaac, Henry T Stelfox, Luc Dubois, Heather L Gill, Timothy Brandys, Sudhir K Nagpal and Derek J Roberts (Canada - Ann Surg.).
The implications of vaping on surgical wound healing: A systematic review - PubMed
Abstract by Omar Ashour, Leen Al-Huneidy and Hilali Noordeen (Jordan, UK - Surgery).
A Biomimetic, Bilayered Antimicrobial Collagen-Based Scaffold for Enhanced Healing of Complex Wound Conditions - Acs.org
Article by Matthew McGrath, Karolina Zimkowska, Katelyn J. Genoud, Jack Maughan, Javier Gutierrez Gonzalez, Shane Browne and Fergal J. O’Brien (Dublin, Ireland - ACS Appl. Mater. Interfaces).
The authors' results indicate that the bilayered scaffold is an excellent candidate for enhancement of diabetic wound healing by preventing wound infection and supporting angiogenesis.
One Center’s Experience With Team-Based Care for Diabetic Foot Ulcers - Hmpgloballearningnetwork.com
Article by Anthony Tickner and Lucy Gachimu (Worcester, USA).
The authors of this column oversee an advanced wound center team, a multidisciplinary, cohesive group with a variety of skills to become more than the sum of its members. Research has shown that a multidisciplinary approach to wound care can improve wound healing, reduce the number of amputations, and improve patient quality of life.
Effect of negative pressure wound therapy on wound thermometry in diabetic foot ulcers - Nih.gov
Article by Vivek Srivastava, Ram Niwas Meena, Arvind Pratap, Awgesh Kumar Verma, Mumtaz Ahmad Ansari and Shashi Prakash Mishra (Varanasi, India - J Family Med Prim Care).
In terms of early formation of granulation tissue, faster wound size reduction, less discomfort, and patient satisfaction, the study indicated that NPWT appeared to be superior. An initial rise in temperature in a DFU may indicate the presence of a pre-ulcerative lesion.
Autophagy is the key to making chronic wounds acute in skin wound healing - Tandfonline.com
Article by Dalibor Mijaljica, Fabrizio Spada, Daniel J. Klionsky and Ian P. Harrison (Australia, USA - Autophagy).
A moist environment is more conducive to skin wound healing as it helps to not only accelerate cell proliferation and migration, and extracellular matrix reorganization, but also promotes autophagy and reduces the incidence of inflammation.
Gene expression changes in therapeutic ultrasound-treated venous leg ulcers - Frontiersin.org
Article by Olivia Boerman, Zahidur Abedin, Rose Ann DiMaria-Ghalili, Michael S. Weingarten, Michael Neidrauer, Peter A. Lewin and Kara L. Spiller (USA - Front. Med.).
Considering the well-known role of chronic inflammation in impairing wound healing in chronic wounds, these results suggest that a downregulation of inflammatory genes is a possible biological mechanism of ultrasound-mediated venous chronic wound healing. Such increased understanding may ultimately lead to the enhancement of ultrasound devices to accelerate chronic wound healing and increase patient quality of life.
The Role of Vitamin D on the Wound Healing Process: A Case Series - Dovepress.com
Article by Fitri Dona Siregar and Wahyu Hidayat (Bandung, Indonesia - International Medical Case Reports Journal).
Vitamin D supplementation has shown effectiveness in wound-healing processes in the oral mucosa.
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