Hungarian Wound Care Society

Sensory neurons play pivotal role in orchestrating tissue repair and regeneration - News-medical.net
Researchers from Monash University and Osaka University have unveiled a groundbreaking discovery regarding the pivotal role of sensory neurons in orchestrating tissue repair and regeneration, offering significant promise for patients with poorly healing tissues and diabetes.

A review of the current state of natural biomaterials in wound healing applications - Frontiersin.org
Article by Mojtaba Ansari and Ahmad Darvishi (Meybod, Iran - Front. Bioeng. Biotechnol.). Biomaterials applied in wound management have advanced significantly. Natural biomaterials are increasingly used due to their advantages including biomimicry of ECM, convenient accessibility, and involvement in native wound healing. However, there are still limitations such as low mechanical properties and expensive extraction methods.

Use of compression therapy for cellulitis - PubMed
Abstract by Mia Nielsen and Mette Midttun (Denmark - Dan Med J.).

Antibiotic bone cement accelerates diabetic foot wound healing: Elucidating the role of ROCK1 protein expression - Wiley.com
Article by Chenglan Yang and Dali Wang (China - International Wound Journal). The study suggests that antibiotic bone cement enhances diabetic foot wound healing, possibly via upregulation of ROCK1.

Application of hyperbaric oxygen therapy in diabetic foot ulcers: A meta-analysis - Wiley.com
Article by Hai-Rong Chen, Shi-Juan Lu, Qi Wang, Ming-Lan Li et al. (Haikou, China - International Wound Journal). The authors' results suggest that HBOT is effective in increasing the complete healing rate and decreasing the amputation rate in patients with DFUs, but increases the incidence of adverse events, while it has no significant effect on mortality.

Impacts of enhanced recovery after surgery nursing interventions on wound infection and complications following bladder cancer surgery: A meta-analysis - Wiley.com
Article by Fan Yang, Jin Nie, Fan Xiao and Juan Liu (Wuhan, China - International Wound Journal). The authors' study indicates that perioperative care based on the ERAS concept remarkably decreased the occurrence of wound infections and complications following BCa surgery, demonstrating notable nursing efficacy and meriting widespread clinical promotion.

Integrated image and location analysis for wound classification: a deep learning approach - Nature.com
Article by Yash Patel, Tirth Shah, Mrinal Kanti Dhar, Taiyu Zhang et al. (Milwaukee, USA - Scientific Reports). The authors' results indicate the potential of their multi-modal network as an effective decision-support tool for wound image classification, paving the way for its application in various clinical contexts.

Cellular and molecular mechanisms of skin wound healing - Nature.com
Abstract by Oscar A. Peña and Paul Martin (Bristol, UK - Nature Reviews Molecular Cell Biology).

Daytime radiative cooling dressings for accelerating wound healing under sunlight - Nature.com
Abstract by Qian Zhang, Chao Qi, Xueyang Wang, Bin Zhu et al. (China - Nature Chemical Engineering).

Topical oxygen therapy and singlet oxygen in wound healing: A scoping review - PubMed
Abstract by Martina Sýkorová, Christine Joy Moffatt, Neil Stentiford, Ewa Anna Burian et al. (UK, Denmark - Int Wound J.)

Follicular unit grafting in chronic ulcers: A valuable technique for integrated management - PubMed
Abstract by Anahi Belatti, Florencia Bertarini, Virginia Pombo, Luis Mazzuoccolo and Damian Ferrario (Buenos Aires, Argentina - An Bras Dermatol.).

Effectiveness of a Multidisciplinary Limb Preservation Program in Reducing Regional Hospitalization Rates for Patients With Diabetes-Related Foot Complications - Sagepub.com
Article by Ali Manji, Reza Basiri, Francois Harton, Kenton Rommens et al. (Alberta, Canada - The International Journal of Lower Extremity Wounds). The study shows that toe and flow model (TFM) effectively reduces hospitalizations and length of stay for diabetic foot complications, with significantly better outcomes in the TFM region than in standard of care regions.

Evaluation of perineal wound healing and pain outcomes after low-angle mediolateral episiotomy in women undergoing vaginal childbirth: A systematic review and meta-analysis - Nih.gov
Article by Qi Luo, Zhai'e Lu and Binbin Xu (Ningbo, China - International Wound Journal). The meta‐analysis revealed significant heterogeneity among studies regarding postoperative pain, and employed a random‐effects model. Results showed that low‐angle episiotomies significantly reduced postoperative pain, and increased first‐degree healing rates compared to traditional angles.

Assessing the Application and Effectiveness of Human Amniotic Membrane in the Management of Venous and Diabetic Ulcers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials - Cureus.com
Article by Abeer A. Alomairi, Rama A. Alhatlani, Shahad M. Alharbi, Zainab J. Alqurain, Ibtihal Z. Alanazi et al. (Saudi Arabia). Despite moderate heterogeneity among studies, the results strongly suggested the effectiveness and safety of HAM therapy for venous and diabetic leg ulcers.

Pressure ulcer risk assessment in the ICU. Is it time for a more objective measure? - PubMed
Abstract by Natalie L McEvoy, Declan Patton, Gerard F Curley and Zena Moore (Intensive Crit Care Nurs.).

What Kind of Dressing Is Important to Ensure Wound Healing With the Application of Platelet-Rich Plasma in Chronic Ulcers? - Cureus.com
Article by Ashraful Hoque (Dhaka, Bangladesh). This case series aims to investigate the advantages of using saltwater dressing following platelet-rich plasma therapy for chronic wounds.

Negative-Pressure Wound Therapy for the Management of Complex Surgical Wounds in a Minority Population - Cureus.com
Article by Max Murray-Ramcharan, Michelle Feltes Escurra, Ryan Engdahl and Federico L. Gattorno (USA). This case series demonstrates desirable wound healing outcomes with the use of NPWT in the minority population. The authors draw attention to the outpatient benefit of this device that may be lost in those with limited insurance in minority populations and seek to encourage further studies in this population in resource-limited settings to determine its true clinical effectiveness.

Potential of Curcumin in the Management of Skin Diseases - Mdpi.com
Article by Kamila Kasprzak-Drozd, Przemysław Niziński, Anna Hawrył, Marek Gancarz et al. (Lublin, Poland - IJMS). This review summarizes the available information on the therapeutic effect of curcumin in treating skin diseases. The results suggest that curcumin may be an inexpensive, well-tolerated, and effective agent for treating skin diseases.

Trauma Wounds: What Are the First Steps? - Woundsource.com
In this interview from SAWC Spring 2023, Greg Patterson describe how to treat a trauma patient from a multidisciplinary point of view.

Skin Tears: Causes, Prevention, and Treatment - Woundsource.com
Article by Cathy L. Harmon. Skin tears are acute, traumatic wounds that result from some mechanical force such as shearing and/or friction or some type of traumatic injury such as from a fall, equipment, or dressings. Those at the risk for skin tears are geriatric patients, the critically ill, and very young patients.

Effect of Diabetes on Wound Healing: A Bibliometrics and Visual Analysis - Dovepress.com
Article by Xiaona Lang, Lu Li, Yuntao Li and Xin Feng (Tianjin, China - Journal of Multidisciplinary Healthcare). Through the metrology method, the time distribution, author institution, cooperation network, research status, research hotspot and development trend of the literature on the influence of diabetes on wound healing were intuitively displayed, which provided a reference for further research and development direction.

Association Between Hemoglobin Levels and Diabetic Foot Ulcer in Patients With Type 2 Diabetes: A Cross-Sectional Study - Hmpgloballearningnetwork.com
Article by Fengying Jiang, Qingyang Liu and Qiubo Wang (Jiangsu, China - Wounds). Anemia is common in patients with DFU. Anemia is a marker of DFU severity, and Hb level can predict poor prognosis in patients with DFU.

Barriers and facilitators to pressure ulcer prevention behaviours by older people living in their own homes and their lay carers: a qualitative study - PubMed
Abstract by Jennifer Roddis, Judith Dyson, Marjolein Woodhouse, Anne Devrell et al. (UK - BMJ Open).

Novel Foam Dressing With Through Holes and Negative Pressure Wound Therapy With Instillation and Dwell Time: A Retrospective Cohort Study - Hmpgloballearningnetwork.com
Article by Carlotta Scarpa, Martina Grigatti, Sandro Rizzato, Alberto Crema et al. (Padua, Italy - Wounds). ROCF-CC dressings were a useful tool in assisting wound bed preparation and reducing time to skin graft closure in this series of complex VLUs.

Promoting diabetic wounds healing using microneedles - Eurekalert.org
In a review a group of researchers from China summarizes the materials of microneedles, techniques, structure, design, release mechanism, classification of delivered substances and their effects on different stages of wound healing.

Incidence and healing times of postoperative sternal wound infections: a retrospective observational single-centre study - PubMed
Abstract by Torbjörn Ivert, Andreas Berge, Sorosh Bratt and Magnus Dalén (Stockholm, Sweden - Scand Cardiovasc J.).

Association between hypertension and pressure ulcer: A systematic review and meta-analysis - Wiley.com
Article by Yanting Huang, Wei Zhou and Haiyang Du (Xiangyang, China - International Wound Journal). There is no significantly statistical association between hypertension and the occurrence of PU in most cases, while the risk of PU significantly elevates among COVID-19 patients combined with hypertension regardless of patient source and study design.

Effects of botulinum toxin type A in the prevention and treatment of facial hypertrophic scars: A meta-analysis - Wiley.com
Article by Jin Lin and Xiao Wang (Hangzhou, China - International Wound Journal). This study indicates that BTX-A is an effective modality in the prophylaxis and treatment of facial hypertrophic scars, significantly alleviating scar-related pain and preventing scar widening, and is thus worthy of broader clinical application.

Effects of cluster nursing interventions on the prevention of pressure ulcers in intensive care units patients: A meta-analysis - Wiley.com
Article by Ai-Guo Zhang, Ling Li, Yuan-Li Li, Shun-Xia Sun et al. (Chongqing, China - International Wound Journal). This study indicates that the application of cluster nursing interventions in ICU patients can effectively reduce the incidence of PUs, as well as improve patients' anxiety and depression levels, thereby enhancing their quality of life, which is worth clinical promotion and application.

Reconstructive Paradigms: A Problem-Solving Approach in Complex Tissue Defects - Mdpi.com
Article by Andreea Grosu-Bularda, Florin-Vlad Hodea, Andrei Cretu, Flavia-Francesca Lita et al. (București, Romania - JCM). The paradigms provide researchers with formulation and solving models for each unique problem, assembling complex entities composed of theoretical, practical, methodological and instrumental elements.

Advanced Wound Healing Techniques Shorten Healing Time in Bladder Cancer - Oncologynurseadvisor.com
Article by Jessica Nye. Advanced wound healing techniques associated with superior outcomes after bladder cancer surgery compared with conventional suture. These findings were published in the International Wound Journal.

A novel in-bed body posture monitoring for decubitus ulcer prevention using body pressure distribution mapping - PubMed
Abstract by Lindsay Stern, Geoff Fernie and Atena Roshan Fekr (Toronto, Canada - Biomed Eng Online).

A standardized wound infection model for antimicrobial testing of wound dressings in vitro - Wiley.com
Article by Cornelia Wiegand, Sarah Fink, Diana C. Mogrovejo, Marina Ruhlandt et al. (Germany, Austria - International Wound Journal). This wound infection model can be used to evaluate new antimicrobial therapeutics as well as to study host-pathogen interactions.

Natural Compounds and Biomimetic Engineering to Influence Fibroblast Behavior in Wound Healing - Mdpi.com
Article by Charlotte E. Berry, Camille Brenac, Caroline E. Gonzalez, Carter B. Kendig et al. (USA - IJMS). The review concludes by describing novel delivery mechanisms aimed at enhancing the bioavailability of natural compounds. Innovative future strategies involve exploring fibroblast-influencing pathways, responsive biomaterials, smart dressings with real-time monitoring, and applications of stem cells.

Roles of Mechanosensitive Channel Piezo1 in Wound Healing and Scar Formation - Mdpi.com
Article by Hans-Oliver Rennekampff, Mayer Tenenhaus, Isabelle Rennekampff and Ziyad Alharbi (Germany, Saudi Arabia - Life). Recognizing the ever-present and critical importance of optimal and reparative wound healing, and with the availability of new physical mechanomodulating devices, the time is ripe for gaining deeper insights into optimizing wound healing. In this review, authors describe the current knowledge of Piezo1 related to wound healing.

Modulation of diabetic wound healing using carbon monoxide gas-entrapping materials - Cell.com
Article by Emily Witt, Alexander J. Leach, Jianling Bi, Samual Hatfield et al. (USA, Canada - Device). The authors demonstrate that CO-GEMs promote the healing response in murine diabetic wound models (full-thickness wounds and pressure ulcers) compared to N2-GEMs and untreated controls.

Study Spotlight: Enhancing Wound Healing with Disposable Hydro-debridement Toolss - Biomiq.health
Article by Robert Fuller. In this article, the author explores a study conducted in 20-18 by researchers on the efficacy of mono-use, disposable hydro-debridement tools and their applications in improving wound healing outcomes.

Successful topical treatment of human biofilms using multiple antibiotic elution from a collagen-rich hydrogel - Nature.com
Article by Ayushi D. Sharma, Evan H. Jarman, Krutika Kuppalli, Matthew J. Murphy et al. (USA - Scientific Reports). Combinations of antibiotics tailored to each patient’s microbiome eluted from a collagen-rich hydrogel successfully treated bacterial cultures isolated from patient samples via an in vitro assay.

Reducing Hospital-acquired Pressure Injuries: SAWC Insights - Woundsource.com
After COVID19, facilities faced nursing shortages, barriers to efficient documentation, and, subsequently, rises in hospital-acquired injuries (HAPI). In this interview from SAWC Fall 2023, Kim Cummings discusses protocols used at her facility that significantly reduced the number of HAPIs.

Retinol helps wounds heal faster, could help countless older people - Medicalxpress.com
Nano micelles of Retinol, a type of vitamin A commonly used in anti-aging beauty products, can also help wounds heal faster by promoting skin tissue regeneration, according to studies conducted by the University of Surrey and Phytoceutical Ltd.

Successful Management of Chronic Wounds by an Autophagy-Activating Magnetized Water-Based Gel in Elderly Patients: A Case Series - Cureus.com
Article by Piercarlo Minoretti, Manuel Gómez Serrano, Andrés Santiago Sáez, Miryam Liaño Riera and Ángel García Martín (Italy, Spain). These preliminary case studies suggest that a topical gel containing magnetized saline water, which promotes autophagy, may aid healing of chronic wounds in elderly patients.

Complementing Braden scale for pressure ulcer risk with clinical and demographic-related factors in a large cohort of hospitalized Italian patients - PubMed
Abstract by Lorenzo Giovannoni, Yari Longobucco, Paolo Iovino, Chiara Barbetti et al. (Florence, Italy - J Tissue Viability).

Healing an ischial tuberosity pressure ulcer in a patient with neurogenic heterotopic ossification: a case report - PubMed
Abstract by Shuntang Li, Qingwen Nong, Yajun Wu and Daen Liu (Nanning, China - J Wound Care).

Early postoperative interventions in the prevention and management of thyroidectomy scars - Frontiersin.org
Article by Nan Hong, Bin Sheng and Pan Yu (Nanjing, China - Front. Physiol.). The authors review the currently adopted early postoperative strategies for thyroidectomy scar reduction, aiming to illustrate the mechanism of these anti-scar methods and provide flexible and comprehensive treatment selections for clinical physicians to deal with thyroidectomy scars.

Vitamin A’s Role in Skin Influences Wound Repair and Hair Growth - Technologynetworks.com
Retinoic acid, a form of vitamin A, can regulate lineage plasticity in skin stem cells, suggests new research from Rockefeller University. The findings, published in Science, could have clinical implications for regenerative medicine, wound healing and even cancer.

Bibliometric analysis of systematic review and meta-analysis on diabetic foot ulcer - Sciencedirect.com
Article by Yanyan Wang, Cong Wang and Lei Zheng (China). Footwear and offloading interventions, multidisciplinary care, hyperbaric oxygen, platelet-rich plasma, and negative pressure wound therapies are highly regarded in terms of intervention. Diabetic foot osteomyelitis, peripheral diabetic neuropathy, chronic limb-threatening ischemia, and infections are the main comorbidities.

YouTube as a source of information for pressure injury: Quality assessment and content analysis - Wiley.com
Article by Myeonghwan Bang, Chan Woong Jang, Han Eol Cho and Hyoung Seop Kim (Republic of Korea - International Wound Journal). The results of this study could be useful for healthcare providers, as well as patients and caregivers, to search for high-quality and reliable YouTube videos related to pressure injury.

Effects of photodynamic therapy in patients with infected skin ulcers: A meta-analysis - Wiley.com
Article by Rui Gu, Sha'ni Fei, Zhaoyu Liu, Xiaoqi Liu, Xiaoxiao Fang et al. (Beijing, China - International Wound Journal). The examined data revealed that photodynamic therapy had a significantly lower wound ulcer size, better tissue repair and lower microbial cell viability compared with red light exposure in subjects with infected skin wounds.

Effectiveness of glutamine and arginine in wound healing of pressure ulcers: A systematic review protocol - PubMed
Abstract by Tim Torsy, Inge Tency, Dimitri Beeckman and Flore De Vylder (Belgium, Sweden - J Tissue Viability).

The Mechanism of Pyroptosis and Its Application Prospect in Diabetic Wound Healing - Dovepress.com
Article by Abdullah Al Mamun, Chuxiao Shao, Peiwu Geng, Shuanghu Wang and Jian Xiao (China - Journal of Inflammation Research). This review presents a brief overview of the molecular mechanisms underlying pyroptosis and addresses the current research on pyroptosis-dependent signaling pathways in the context of diabetic wound healing.

Negative Pressure Wound Therapy: Challenges, Novel Techniques and Future Perspectives - PubMed
Abstract by Corey Keenan, Noor Obaidi, Jamie Neelon, Irene Yau et al. (USA - Adv Wound Care (New Rochelle)).

The role of the skin microbiome in wound healing - PubMed
Abstract by Yuyan Yang, Jiuzuo Huang, Ang Zeng, Xiao Long et al. (Beijing, China - Burns Trauma).

Effect of two different modalities of hysterectomy on wound infection and wound dehiscence in obese patients - Wiley.com
Article by Ling Long, Xuan He, Yuyang Liu and Cuirong Lei (Chongqing, China - International Wound Journal). The application of laparoscopy to overweight women who have had a hysterectomy results in a reduction in the expected amount of bleeding during surgery and a reduction in the risk of post-operative wound infections.

Effects of predictive nursing interventions on pressure ulcer in older bedridden patients: A meta-analysis - Wiley.com
Article by Zhu-Feng Liu, Juan Meng, Na Jing and Xiao-Yun Liu (Jinan, China - International Wound Journal). This study shows that the implementation of a predictive nursing interventions for elderly bedridden patients can effectively reduce the occurrence of pressure ulcers and significantly improve patients' satisfaction with nursing care, which is worthy of clinical promotion and application.

Effect of quality nursing intervention on wound healing in patients with burns: A meta-analysis - Wiley.com
Article by Ling Liu, Zhu-Feng Liu, Hong-Yu Zhu and Hui-Qin Xu (Jinan, China - International Wound Journal). This meta-analysis shows that applying quality nursing interventions in patients with burns can significantly shorten the wound healing time and reduce the incidence of wound infection and complications, thus promoting early patient recovery.

Ablation VS Laceration: What’s the Difference - Woundsource.com
In this interview from SAWC Spring 2023, Greg Patterson and Mary Ann Obst describe the difference between a laceration and an abrasion. These trauma wounds have key differences that are important to consider in acute care.

MRSA: The Basics - Woundsource.com
Article by Cathy L. Harmon. Methicillin-resistant Staphylococcus aureus, more commonly referred to as MRSA, is a bacterial organism resistant to many antibiotics, in particular the -cillins. The overuse and misuse of antibiotics in the past several decades has contributed to its resistance to certain antibiotics. The most common cause of MRSA is group A Streptococcus.

Role of Data in Wound Care - Woundsource.com
Big data analytics may assess treatments received by millions of patients and may provide which treatment, product, or protocol had favorable outcomes. Experts have started using ML to make workflow improvements, for inpatient monitoring and outpatient communication, and for general hospital operations to increase the efficiency and efficacy of care delivery, as well as decrease complications.

Impact of nutrition on skin wound healing and aesthetic outcomes: A comprehensive narrative review - Sciencedirect.com
Article by Ishith Seth, Bryan Lim, Jevan Cevik, Dylan Gracias et al. (Austria, Denmark, Italy - JPRAS Open). Personalized nutritional plans are essential in surgical care, particularly for enhanced recovery after surgery protocols. Despite the demonstrated benefits of certain nutrients, gaps in research, particularly regarding elements such as iron, necessitate further studies.

Insight into the Antioxidant Activity of Ascorbic Acid-Containing Gelatin Nanoparticles in Simulated Chronic Wound Conditions - Mdpi.com
Article by María del Carmen Morán, Cristina Porredon and Coloma Gibert (Barcelona, Spain - Antioxidants). The proposed gelatin-based NPs showed promising properties as biocompatible inductors of proliferation in both fibroblast and keratinocyte cell lines.

Exploration of the anti-inflammatory, analgesic, and wound healing activities of Bletilla Striata polysaccharide - Sciencedirect.com
Abstract by Xiaomei He, Longyun Liu, Fangli Gu, Renshu Huang et al. (China - International Journal of Biological Macromolecules).

Need for Percent Area Reduction and Percent Volume Reduction Measurements in Diagnostic Wound Imaging: A Statement From the Wound Care Collaborative Community - Part 1 - Hmpgloballearningnetwork.com
Article by Alisha Oropallo,Peggy Dotson, Tod Brindle, Vickie R Driver and Lisa Gould (USA - Wounds). As the WCCC TWG strives to address concerns and enhance wound imaging tools, it becomes evident that these tools, when meeting established criteria and undergoing proper evaluation, could be deemed as ‘digital biomarkers.’ These digital biomarkers, with their potential to provide consistent and accurate measurements, hold promise in advancing the field of wound care and improving patient outcomes.

To Debride or Not to Debride: A Review of Wound Management for Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis - Cureus.com
Article by Christina D. Enescu, Adam J. Elder, Hany Deirawan and Meena Moossavi (Detroit, USA). The goal of this review is to explore and compare the two treatment approaches for SJS and TEN, namely conservative management and surgical debridement.

Multi-resistant organisms in burn patients: Is this the end or a new beginning? - Sciencedirect.com
Abstract by Ahmed Hagiga és Baljit Dheansa (East Grinstead, UK - Burns).

Multi-disciplinary diabetic limb salvage programme in octogenarians with diabetic foot ulcers is not futile: An observational study with historical controls - Wiley.com
Article by Lixia Ge, Jiashen Zhao, Matthew Tan, Elaine Tan, Huiling Liew et al. (Singapore - International Wound Journal). The authors' findings suggest that the programme yielded favourable impacts on the clinical outcomes of patients aged≥80 years with DFUs.

The infected diabetic foot: Analysis of diabetic and non-diabetic foot infections - PubMed
Abstract by Lawrence A Lavery, Mehmet A Suludere, Easton Ryan, Peter A Crisologo et al. (USA, Australia - Wound Repair Regen.).

Risk factors and clinical characteristics of surgical site infections in athletes undergoing Achilles tendon repair surgery - Wiley.com
Article by Chenhao Guo, Yuze Zhang, Wenhan Dong, Bo Huang and Yinghai Liu (Taiyuan, China - International Wound Journal). Critical risk factors such as absence of prophylactic antibiotics, diabetes, open wounds and extended surgery duration play a vital role in SSIs. Addressing these factors is essential for better postoperative outcomes in Achilles tendon repair surgeries.

Chitosan-Based Biomaterial in Wound Healing: A Review - Cureus.com
Article by Suba Rajinikanth B, Densingh Samuel Raj Rajkumar, Keerthika K and Vinothini Vijayaragavan (India). The article analyzes the depth of chitosan-based biomaterials and their impact on wound healing and also the methods to enhance the advantages of chitosan by incorporating bioactive compounds.

Controlling the microenvironment to promote wound healing and regeneration - Phys.org
The Korea Research Institute of Standards and Science has unveiled a new principle for controlling the microenvironment of biological tissues to promote wound healing and regeneration. This discovery holds significant promise for the development of wound healing medication as well as research on fibrotic diseases and cancer.