Cell Migration Assays and Their Application to Wound Healing Assays – A Critical Review - Mdpi.com
Article by Chun Yang, Di Yin, Hongbo Zhang, Ildiko Badea et al. (China, Canada - Micromachines).
This paper provides a comprehensive and critical review of the development of cell migration assays (CMAs) along with their application to wound healing assays. One salient feature of their methodology in this paper is the application of the so-called design thinking; namely they define the requirements of CMAs first and then take them as a benchmark for various developments of CMAs in the literature.
Dermatologists Manage a Minority of Patients With Chronic Wounds, Study Finds - Medscape.com
Article by Doug Brunk.
Between 2011 and 2019, chronic cutaneous wounds accounted for about one third of all healthcare visits for cutaneous wounds, and the most common diagnoses were open wounds of the thumb without nail damage. However, fewer than 8% of chronic wounds were managed by dermatologists during this time.
Ethical considerations in mitigating wound-care with ablution religious practices - Jaad.org
Article by Aarushi K Parikh and Shari R Lipner (USA - J Am Acad Dermatol.).
Dermatologists must continue to support and advocate for their patients' well-being, even when patients may not adhere to medical advice. However, ultimately, while dermatologists have a 85 responsibility to provide patients with the necessary information and guidance for wound care, patients retain autonomy over their own healthcare decisions.
Extracorporeal Shockwave Therapy (ESWT) in an Outpatient Wound Care Clinic: Case Series Analysis of a Non-Invasive Technology in the Management of Chronic Wounds for Wound Bed Preparation - Hmpgloballearningnetwork.com
Article by Denise Nemeth and Jayesh B Shah (San Antonio, USA).
ESWT could offer accessible, fast, safe, and cost-effective management of some complex chronic wounds. Further research is needed to validate these findings.
Clinical Applications of Adipose-Derived Stem Cell (ADSC) Exosomes in Tissue Regeneration - Mdpi.com
Article by Konstantinos S. Papadopoulos, Christina Piperi and Penelope Korkolopoulou (Athens, Greece - IJMS).
The authors address the main characteristics and functional properties of ADSC-exos in tissue regeneration and explore their most recent clinical application in wound healing, musculoskeletal regeneration, dermatology, and plastic surgery as well as in tissue engineering.
Light Therapy Can Increase Brain Connectivity Following Injury - Technologynetworks.com
Lights of different wavelengths have been studied for years for their wound-healing properties.
Exploring Thermal Dynamics in Wound Healing: The Impact of Temperature and Microenvironment - Dovepress.com
Article by Jun Huang, Chunjie Fan, Yindong Ma and Guobao Huang (Jinan, China - Clinical, Cosmetic and Investigational Dermatology).
This work presents a forward-looking perspective on refining wound management through sophisticated, evidence-based interventions, emphasizing the interplay between thermal dynamics and wound healing.
Understanding the Importance of Proteins in The Wound Healing Process - Abintrausa.com
Proteins play a crucial role in the process of wound healing, from the initial inflammation to the final remodeling of the healed tissue, serving as the building blocks for wound repair and regeneration.
Advances of Nanobiomaterials for Treating Skin Pathological Fibrosis - Wiley.com
Article by Yongyuan Kang, Xiaowei Liu, Xiping Chen, Yiyuan Duan et al. (China - Advanced Nanobiomed Research).
Integrating nanomaterials or nanostructures into hydrogels, nanofibers, and microneedles can enhance the biological functionality and maximize the therapeutic effect of nanoparticles at the wound site.
The Relationship Between Elbow Instability and Wound Healing: A Report of Four Cases - Sciencedirect.com
Article by Andrew R. Phillips, James S. Lin and Kanu S. Goyal (Columbus, USA - Journal of Orthopaedic Reports).
Each of the cases emphasizes the importance of achieving elbow stability to prevent SCFs and further wound complications, though further rigorous studies are required to definitively establish a causal relationship.
Venous Leg Ulcers and Comorbidities - Woundsource.com
Venous leg ulcers (VLUs) are often the result of chronic venous insufficiency and venous hypertension, which cause retrograde venous flow or venous obstruction and require long-term monitoring and management. Patients with chronic venous disease often have comorbid conditions that may also contribute to VLU formation and delayed healing. It is essential to manage comorbidities appropriately, because uncontrolled comorbid conditions can increase the risk of VLU development.
Venous Leg Ulcer Recurrence: How to Prevent - Woundsource.com
In this interview, Windy Cole discusses the factors that contribute to the high recurrence rate of venous leg ulcers.
Enhanced wound regeneration by PGS/PLA fiber dressing containing platelet-rich plasma: an in vitro study - Nature.com
Article by Parisa Heydari, Anousheh Zargar Kharazi and Laleh Shariati (Isfahan, Iran - Scientific Reports).
Based on the results obtained, the PGS/PLA-PRP dressing developed might be a promising evolution in skin tissue engineering ensuring improved wound healing and tissue regeneration.
Microneedles for Enhanced Bacterial Pathogen Inactivation and Accelerated Wound Healing - Wiley.com
Article by Akshay Krishnakumar, Nicholas L.F. Gallina, Devendra Sarnaik, Robyn R McCain et al. (West Lafayette, USA - Advanced Materials Technologies).
In vitro, antibacterial efficacy of the microneedles is validated against two common wound pathogens, Pseudomonas aeruginosa (P. aeruginosa) and Staphylococcus aureus (S. aureus).
Factors Influencing Wound Healing in Diabetic Foot Patients - PubMed
Abstract by Sang Heon Lee, Sung Hwan Kim, Kyung Bum Kim, Ho Sung Kim and Young Koo Lee (South Korea - Medicina (Kaunas)).
Biomaterials for immunomodulation in wound healing - PubMed
Abstract by Ying Wang, Katrina Vizely, Chen Yu Li, Karen Shen, Amid Shakeri et al. (Canada, USA - Regen Biomater.).
Pressure Injury Prevention in Adult Critically Ill Patients: A Best Practice Implementation Project - PubMed
Abstract by Aline de Oliveira Ramalho (Am J Nurs.).
Epidemiological characteristics and factors affecting healing in unintentional pediatric wounds - Frontiersin.org
Article by Hua Gao, Yang Li, Shaobin Jin, Wenli Zhai et al. (Shandong, China - Front. Public Health).
In children, the common sites of unintentional skin lacerations show distinct age and gender distribution characteristics. Older age, outdoor injuries, longer wound lengths, and lower limb injuries are independent risk factors for poor wound healing.
Controlled oxygen delivery to power tissue regeneration - Nature.com
Article by Elizabeth Zoneff, Yi Wang, Colin Jackson, Oliver Smith, Serena Duchi et al. (Australia - Nature Communications).
In this review, the authors explore the biological relevance of oxygen at both a cellular and tissue level, and the importance of its controlled delivery via engineered biomaterials and devices.
The Negative Impact of Vaping and Electric Cigarettes for Healing of Acute Wounds: A Literature Review - Ijmscr.org
Abstract by Machfira Bulantrisna and Ahmad Fawzy (Indonesia - Int. J. of Medical Science and Clinical Research Studies).
Recent advances in molecular mechanisms of skin wound healing and its treatments - Frontiersin.org
Article by Abdullah Al Mamun, Chuxiao Shao, Peiwu Geng et al. (China - Front. Immunol.).
This review provides an updated overview of recent advancements in chronic wound healing and therapeutic management using innovative approaches.
Multiplicative Effects of Essential Oils and Other Active Components on Skin Tissue and Skin Cancers - Mdpi.com
Article by Hyeong Jae Kim and Jeong Hee Hong (Incheon, South Korea - IJMS).
This review provides a basis for the development of novel therapies for skin diseases and cancers, especially melanoma.
Pressure injury education for older adults and carers living in community settings: A scoping review - PubMed
Abstract by Ashlyn Sahay, Eileen Willis and Stephen Yu (Norman Gardens, Australia - Int Wound J.).
Researchers design new regenerative medicine therapy to accelerate diabetic wound repair - News-medical.net
Researchers at the Icahn School of Medicine at Mount Sinai have designed a regenerative medicine therapy to speed up diabetic wound repair. Using tiny fat particles loaded with genetic instructions to calm down inflammation, the treatment was shown to target problem-causing cells and reduce swelling and harmful molecules in mouse models of damaged skin.
Skin fragility and wound management in Ehlers- Danlos Syndrome: a report by the Ehlers Danlos Syndrome society skin working group - Oup.com
Abstract by Chloe Angwin, Brent J Doolan, Ingrid Hausser, Barry Labine et al. (UK, Germany, USA, Australia - Clinical and Experimental Dermatology).
Evaluation of the Biological Activity of Manna Exudate, from Fraxinus ornus L., and Its Potential Use as Hydrogel Formulation in Dermatology and Cosmetology - Mdpi.com
Article by Carla Villa, Francesco Saverio Robustelli della Cuna, Elena Grignani, Sara Perteghella et al. (Italy - Gels).
All the peculiarities that make the pectin hydrogels ideal systems for skin disease, as wound dressings and for antiaging cosmetic formulations.
Effect of Topical Silver Nanoparticle Formulation on Wound Bacteria Clearance and Healing in Patients With Infected Wounds Compared to Standard Topical Antibiotic Application: A Randomized Open-Label Parallel Clinical Trial - Cureus.com
Article by Basanti K. Pathi, Subrajit Mishra, Niranjan Moharana, Abinash Kanungo et al. (Bhubaneswar, India).
Kadermin, the silver nanoparticle-based cream, has better efficacy in achieving faster wound bacteria clearance and healing in infected wounds compared to Mupirocin. This may have relevance for its use as an antibiotic-sparing agent in wound management.
Therapeutic Potential of Bovine Milk-Derived Extracellular Vesicles - Cureus.com
Article by Madhusha Prasadani, Suranga Kodithuwakku, Georgia Pennarossa, Alireza Fazeli and Tiziana A. L. Brevini (Estonia, Sri Lanka, Italy, UK - IJMS).
Although a number of aspects still need to be further elucidated, the available data point to the role of milk extracellular vesicles as a potential candidate with therapeutics potential, and the supplementation of milk extracellular vesicles would pave the way to understanding their in-depth effects.
In vitro evaluation of a hybrid negative pressure system for wound therapy - Wiley.com
Article by Jack S Davey, Wye Li Chong, Jake Fountain, Jane Heller et al. (Australia - Vet Surg.).
The h-NPWT system achieved negative pressures that were comparable to those of a commercial control NPWT device. The addition of tubing between the skin substrate and the canister did not affect the pressure applied at the wound site.
Preventing Maceration in Wounds - Woundsource.com
Maceration occurs when skin has been exposed to moisture for too long. By identifying patients who are at risk of developing wound maceration and providing appropriate care, clinicians can prevent wound maceration.
Clearing The Air About Moist Vs. Dry Wound Healing - Woundsource.com
Article by Bruce E. Ruben.
Cell growth needs moisture and the main goal of moist wound therapy is to create and maintain these optimal moist conditions. Cells can grow, divide and migrate at an increased rate to enhance the formation of new tissue.
Negative Pressure Wound Therapy versus Conventional Dressing in Lower Limb Fractures: Systematic Review and Meta-analysis - Lww.com
Article by André S. Alves, Jérôme Martineau, Matteo Scampa, Daniel F. Kalbermatten and Carlo Oranges (Geneva, Switzerland - Plastic & Reconstructive Surgery-Global Open).
NPWT appears to be a reasonable option for wound management in Gustilo 3 lower limb fractures in terms of infection rates.
Improved Treatment Outcome Following the Use of a Wound Dressings in Cutaneous Leishmaniasis Lesions - Mdpi.com
Article by Pedro B. Borba, Jamile Lago, Tainã Lago, Mariana Araújo-Pereira et al. (Brazil - Pathogens).
The authors' results show that the application of wound dressings to Cutaneous Leishmaniasis (LS) lesions can improve chemotherapy outcome in CL caused by L. braziliensis.
Content of a wound care mobile application for newly graduated nurses: an e-Delphi study - Biomedcentral.com
Article by Julie Gagnon, Julie Chartrand, Sebastian Probst and Michelle Lalonde (Canada - BMC Nursing).
The results of this study will inform the development of the initial content of the algorithm for a wound care mobile application. Expert participation and their insights on infection-related matters have the potential to support evidence-based wound care practice. Ongoing debates surround items without consensus. Finally, this study establishes expert wound care nurses’ perspectives on the competencies anticipated from newly graduated nurses.
Effects of Topical Insulin on Second-Degree Burn Wound Healing: Brief Report - Hmpgloballearningnetwork.com
Article by Vagner Franco da Silveira Jr., Juliany Lino Gomes Silva, Maria Helena Melo Lima and Mario Jose Abdalla Saad (Campinas, Brazil - Wound Management & Prevention).
In this study, topical insulin reduced healing time in second-degree burns. Further investigation is warranted to support wider use in clinical practice.
Healing faster: Unveiling the future of tissue & organ repair - Eurekalert.org
Cutting-edge research co-led by University of Ottawa's Dr. Emilio I. Alarcón could impact millions of lives with peptide-based hydrogels that will close skin wounds, deliver therapeutics to damaged heart muscle and reshape and heal injured corneas.
Antibacterial activity of medicinal plants and their role in wound healing - Springeropen.com
Article by Zeinab Breijyeh and Rafik Karaman (Israel, Italy - Future Journal of Pharmaceutical Sciences).
Phytomedicine is one of the top options for the treatment of chronic illnesses for millions of people around the world. To learn about the bioactive components of medicinal plants, their medical benefits, and their synergistic or additive effects to enhance the action of medications, substantial new studies are still needed.
Mast cells and wound healing: Still an open question - PubMed
Abstract by Montserrat Fernández-Guarino and Stefano Bacci (Spain, Italy - Histol Histopathol.).
In vitro analysis of interactions between Pseudomonas aeruginosa and Candida albicans treated with silver sulfadiazine in wound infections - PubMed
Abstract by Preetha Kamath, Suchismita Paul, Jose Valdes, Joel Gil et al. (Miami, USA - JAC Antimicrob Resist.)
Advancements in Dermatological Applications of Curcumin: Clinical Efficacy and Mechanistic Insights in the Management of Skin Disorders - Dovepress.com
Article by Zhiming Mo, Jiayi Yuan, Xuelian Guan and Jianhong Peng (Dongguan, China - Clinical, Cosmetic and Investigational Dermatology).
The integration of curcumin into dermatological practice requires a balanced consideration of evidence-based efficacy and safety. Curcumin’s comprehensive utility in dermatology, coupled with the necessity for advanced scientific exploration, emphasizes the importance of combining traditional knowledge with contemporary research to improve patient care in dermatology.
Technologies used in the treatment of burn victims in intensive care: a scope review - Scielo.br
Article by Kyohana Matos de Freitas Clementino, Gabriela Duarte Bezerra, Gleice Adriana Araujo Gonçalves, Maria Corina Amaral Viana et al. (Crato, Brazil - Rev. Bras. Enferm.).
The study identified essential technologies in burn care, emphasizing the need for further research on “soft” technologies. The findings support the promotion of evidence-based nursing care for burn patients in intensive care and enhance knowledge about effective treatments.
A Multi-Faceted Digital Health Solution for Monitoring and Managing Diabetic Foot Ulcer Risk: A Case Series - PubMed
Abstract by Emily Matijevich, Evan Minty, Emily Bray, Courtney Bachus et al. (Canada, USA - Sensors (Basel)).
Pressure injury treatment by intermittent electrical stimulation (PROTECT-2): protocol for a multicenter randomized clinical trial - PubMed
Abstract by Chase Donaldson, Marcelo Gama de Abreu, Edward J Mascha, James Rowbottom et al. (USA, Austria, Canada - Trials).
Is the varying management of incontinence-associated dermatitis due to a lack of understanding of etiology? - PubMed
Abstract by Michelle Porter (Lincolnshire, UK - Br J Community Nurs.)
Breakthrough in hemostasis and wound healing research - Sciecedaily.com
A breakthrough study features a biomedical engineering innovation with the potential to transform trauma care and surgical practices. A scientific research team has developed platelet-like particles that integrate into the body's clotting pathways to stop hemorrhage.
Infection-Free and Enhanced Wound Healing Potential of Alginate Gels Incorporating Silver and Tannylated Calcium Peroxide Nanoparticles - Mdpi.com
Article by Alexandra Catalina Bîrcă, Oana Gherasim, Adelina-Gabriela Niculescu, Alexandru Mihai Grumezescu et al. (Bucharest, Romania - IJMS).
The biofilm modulation data indicated a synergistic antimicrobial effect between silver and tannylated calcium peroxide nanoparticles, with a prominent inhibitory action against the Gram-positive bacterial biofilm after 48 h.
Pre-Incisional and Multiple Intradermal Injection of N-Acetylcysteine Slightly Improves Incisional Wound Healing in an Animal Model - Mdpi.com
Article by Wiktor Pascal, Antoni Smoliński, Mateusz Gotowiec, Marta Wojtkiewicz et al. (Poland, USA - IJMS).
The authors' results point to a limited efficacy of multiple N-acetylcysteine injections post-surgery in wound healing.
Improved wound healing with a modified electrosurgical electrode - Woundsource.com
Abstract by P. E. M. Butler, C. Barry-Walsh, B. Curren, P. A. Grace et al. (Dublin, Ireland - British Journal of Plastic Surgery).
Identifying the Different Types of Wound Drainage - Woundsource.com
As health care professionals monitor the wound drainage of a patient, it is critical to be able to recognize the different types of wound drainage. Open wounds and incision wounds may both present varying types of exudate, some of which are perfectly healthy and others that can signal an infection or slow healing.
The Four Stages of Wound Healing - Woundsource.com
The stages of wound healing proceed in an organized way and follow four processes: hemostasis, inflammation, proliferation and maturation. Although the stages of wound healing are linear, wounds can progress backward or forward depending on internal and external patient conditions.
Compression and Wound Patient Adherence - Woundsource.com
In this interview, Dr. Naz Wahab discusses why patients can have difficulty adhering to compression garments or compression materials, and how their providers can help address these difficulties.
An Injectable, Self-Healing, Adhesive Multifunctional Hydrogel Promotes Bacteria-Infected Wound Healing - Mdpi.com
Article by Ling Zhang, Yan Wang, Mingrui Yang, Wen Yu et al. (China - Polymers).
The authors' results prove that the P(LA-SL)-PA hydrogels could act as effective wound dressings for promoting the healing of infected wounds.
Learning update: Focus on wound care - Pharmacymagazine.co.uk
Article by Richard Thomas.
Superficial damage to the skin occurs often in everyday life and triggers the three-stage process of wound healing: inflammation, proliferation and remodelling. It is important to create the optimal environment for wounds to heal while minimising scar formation.
Efficacy of Honey-Based Wound Dressing Versus Hydrogel-Based Wound Dressing in Wound Healing Process: A Literature Review - Imscr.org
Article by Firda Rahmania and Ahmad Fawzy (Indonesia - International Journal of Medical Science and Clinical Research Studies).
The efficacy of honey dressing surpasses that of hydrogel dressing in wound management. Honey's multifaceted properties, including its potent antimicrobial activity, ability to promote tissue regeneration, and anti-inflammatory effects, make it a superior choice for wound healing across all phases.
Is there a best way to remove dead tissue from surgical wounds? - Cochrane.org
Article by F. Smith, J. Donaldson and T. Brown.
We cannot be certain whether removal of dead or infected tissue of surgical wounds or care that is usually provided makes any difference to how long it takes to remove all of the dead tissue from the wound and for the wound to heal.
In vivo and in silico Studies of Effects of Oil Extracted from Cannabis sativa L. Seeds on Healing of Burned Skin Wounds in Rats - Frontiersin.org
Abstract by Mouna Bouarfa, Mohamed Chebaibi, Fatima Ez-Zahra Amrati, Zouhair Souirti et al. (Morocco, Turkey, USA, Saudi Arabia - Front. Chem.).
Is Shock Wave Application Effective on Various Chronic Wounds in the Geriatric Population? Preliminary Clinical Study - Tandfonline.com
Article by Robert Dymarek, Izabela Kuberka, Karolina Walewicz, Jakub Taradaj et al. (Poland - Clinical Interventions in Aging).
The ESWT application yields substantial immediate clinical effects that support the healing of chronic wounds in older adults. Even a single ESWT session can prove to be clinically effective and beneficial in the management of chronic wounds.
Acute Surgical and Rehabilitation Management of Complex Hand Burns in Combat Casualties - Mdpi.com
Article by Jill M. Cancio, Jonathan B. Lundy and Leopoldo C. Cancio (Fort Sam Houston - European Burn Journal).
Basic treatment principles for the acutely burned hand include edema management; early wound coverage, including excision of the burn and skin grafting; early and aggressive hand therapy; and burn-scar contracture mitigation strategies.
Impact of oral nutritional supplement composition on healing of different chronic wounds: A systematic review - Sciencedirect.com
Abstract by Allan Carlos Soares do Espírito Santo, Clara Sandra de Araújo Sugizaki, Alcides Corrêa de Morais Junior, Nara Aline Costa et al. (Goiânia, Brazil - Nutrition).
Lower limb lymphedema disrupts both static and dynamic balance - Nih.gov
Abstract by Özlem Karasimav, Pınar Borman, Meltem Dalyan, Elif Yalçin et al. (Ankara, Turkey - Clin Biomech (Bristol, Avon)).
Characterization of a full-thickness decellularized and lyophilized human placental membrane for clinical applications - Wiley.com
Article by Bradley Wetzell, Britini Ork, Davorka Softic, Jennifer Morse, William Hutchens et al. (Virginia Beach, USA - International Wound Journal).
It was accepted as a natural scaffold in vivo with evidence of host-cell infiltration, angiogenesis, tissue remodelling, and structural layer retention for up to 10 weeks in a murine subcutaneous implant model.
A survey of skin failure perceptions amongst pressure injury management staff in China: A cross-sectional study - Wiley.com
Article by Xiaodan Lu, Bingbing Wu, Qian Li, Xuyang Wang et al. (Hangzhou, China - International Wound Journal).
Participants exhibited a positive attitude towards skin failure, highlighting the need for future improvements in skin failure training.
Unraveling the Mechanisms Involved in the Beneficial Effects of Magnesium Treatment on Skin Wound Healing - Mdpi.com
Article by Yuta Yoshino, Tatsuki Teruya, Chika Miyamoto, Mai Hirose, Satoshi Endo and Akira Ikari (Gifu, Japan - IJMS).
The authors' results revealed that MgCl2 inhibits epidermal differentiation but promotes cell migration, suggesting that applying magnesium to the early wound healing process could be beneficial.
Improving outcomes for patients with hard-to-heal wounds following adoption of the Wound Hygiene Protocol: real-world evidence - Magonlibrary.com
Abstract by Rachel Torkington-Stokes, Kate Moran, Diego Sevilla Martinez, Deborah Cesura Granara and Daniel Gary Metcalf (UK, Spain, Italy - Journal of Wound Care).
Safety and effectiveness of an antiseptic wound cleansing and irrigation solution containing polyhexamethylene biguanide - Magonlibrary.com
Abstract by Mark G Rippon, Kristian Daly, Alan A Rogers and Samantha Westgate (UK - Journal of Wound Care).
Gelatin-based biomaterials and gelatin as an additive for chronic wound repair - Frontiersin.org
Article by Hongwei Cao, Jingren Wang, Zhanying Hao and Danyang Zhao (Shenyang, China - Front. Pharmacol.).
In this article, the authors introduce the natural process of wound healing. They present the role of gelatin-based biomaterials and gelatin as an additive in wound healing.
Hydrogel Dressings - News-medical.net
Article by Liji Thomas.
Hydrogel dressings are an emerging area for wound care, as they increase the speed and success of wound healing.
Supporting patients with venous leg ulcers in self-care monitoring: an interview study with primary health care professionals - Tandfonline.com
Article by Natali Johnsson, Cecilia Fagerström, Catharina Lindberg and Hanna Tuvesson (Sweden - Scandinavian Journal of Primary Health Care).
Primary health care professionals actively monitor patients’ self-care and establish caring relationships. They see a need for a structured primary health care work routine for ulcer management.
Superbugs: More About Key Drug-Resistant Organisms - Woundsource.com
At present, estimates place drug-resistant organisms as causing over 700,000 deaths per year globally. By 2050, predictions say that the number of deaths caused by these organisms could surpass mortalities caused by cancer, nearly 10 million deaths per year. Thus, it is important to understand how these organisms work and know several strategies for combatting these infections while adhering to antimicrobial stewardship best practices.
When to Use Antimicrobials and Why - Woundsource.com
In this interview, Christine Miller discusses judicious use of antimicrobials in wound care, especially related to the care of chronic wounds.
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