An Evidence-Based, Sustainable Solution for Wound Management in Low-Resource Settings: Part 1 - Woundsource.com
Article by Linda Benskin and Richard Benskin.
At any given time, as many as one in five adults in rural areas of tropical developing countries experience incapacitation due to a wound. This series summarizes 20+ years of research, culminating with testing Available Technology Dressings (ATDs), a very specific sustainable moist dressing technique which can be taught to patients and lay health care providers. Part 1 addresses the Available Technology Dressing (ATD) controlled trial.
Cutaneous Wound Healing and the Effects of Cannabidiol - Mdpi.com
Article by Pearl Shah, Kathryne Holmes, Fairouz Chibane, Phillip Wang et al. (USA - IJMS).
The authors' data support the potential use of CBD to improve diabetic cutaneous wound healing.
Use of a Novel Human Keratin Matrix Improves Healing Rates in Diabetic Lower Extremity Wounds - Hmpgloballearningnetwork.com
Article by Allison N. Ramey-Ward and Ryan Chatelain (USA).
The authors' results suggest that human keratin matrix may help regulate the pathological processes that contribute to wound chronicity to “kick-start” wound healing. This case series demonstrates that HKM is a promising technology to improve healing rates in nonhealing lower extremity wounds in patients with diabetes.
Evaluating the Efficacy of Topical Phenytoin in the Healing of Neuropathic Diabetic Foot Ulcers: A Comparative Study - Cureus.com
Article by Tabana C., Shaheen Banu A. and Saravanakumar Ganesan (Sivagangai, India).
Topical phenytoin demonstrated a promising enhancement in the healing of mildly infected neuropathic diabetic foot ulcers compared to conventional dressings.
Reconstructive Options for Pressure Ulcers in Pediatric Patients - PubMed
Abstract by Dominika Krakowczyk, Jakub Opyrchał, Tomasz Koszutski, Krzysztof Dowgierd and Łukasz Krakowczyk (Poland, Children (Basel)).
Patient participation in surgical wound care in acute care settings: An integrative review - Sciencedirect.com
Article by Kita Liosatos, Georgia Tobiano and Brigid M. Gillespie (Australia - International Journal of Nursing Studies).
This review highlights opportunities to personalise and prioritise a patient-oriented approach to surgical wound care. Clinicians and educators should adopt an individualised approach by tailoring patient participation based on patient factors (i.e. physical symptoms) and adopt patient-centred communication approaches.
Studies on bioactivities of Manuka and regional varieties of honey for their potential use as natural antibiotic agents for infection control related to wound healing and in pharmaceutical formulations - PubMed
Abstract by Divakar Dahiya, Caoimhin Mackin and Poonam Singh Nigam (UK - AIMS Microbiol.).
Unravelling the Microbiome's Role in Healing Diabetic Wounds - PubMed
Abstract by Sanchit Dhankhar, Nitika Garg, Samrat Chauhan, Monika Saini et al. (India - Curr Pharm Biotechnol.).
Synthesis of Transparent Bacterial Cellulose Films as a Platform for Targeted Drug Delivery in Wound Care - Mdpi.com
Article by Julia Didier Pedrosa de Amorim, Yasmim de Farias Cavalcanti, Alexandre D’Lamare Maia de Medeiros, Cláudio José Galdino da Silva Junior et al. (Brazil - Processes).
This study highlighted bacterial cellulose (BC) properties and drug incorporation and release behavior. The findings contribute towards optimizing wound dressings with controlled drug release, showcasing the potential of transparent BC films as an effective platform for wound care and drug-delivery applications.
Negative Pressure Level and Effects on Bacterial Growth Kinetics in an in vitro Wound Model - PubMed
Abstract by Adam Bobkiewicz, Wojciech Francuzik, Amy Martinkosky and Maciej Borejsza-Wysocki (Poland, Germany - Pol J Microbiol.).
Spiny mice hold the key to regenerative wound healing - Drugdiscoverynews.com
Article by Luisa Torres.
Understanding tissue regeneration in spiny mice could help improve human wound healing.
Repairing Exposed Tendon Wounds with Absorbable Gelatin Sponges and Autologous Split-Thickness Skin Grafts: A Case Series - Lww.com
Article by Gang Jing and LinLin Wang (Hainan, China - Adv Skin Wound Care).
The proposed method proved successful in repairing exposed tendon wounds, effectively preventing infection and necrosis.
Prophylactic dressings to prevent sacral pressure injuries in adult patients admitted to intensive care units: A three-arm feasibility randomized controlled trial - Sciencedirect.com
Article by Sharon Latimer, Rachel M Walker, Wendy Chaboyer, Lukman Thalib et al. (Australia - Intensive Crit Care Nurs.).
Rigorous comparative effectiveness evidence on prophylactic sacral dressings is needed so clinicians, managers and policy makers can make informed practice decisions based on performance, preference, and cost-effectiveness.
Evaluation of a Semi-Automated Wound-Halving Algorithm for Split-Wound Design Studies: A Step towards Enhanced Wound-Healing Assessment - Mdpi.com
Article by Paul Julius Georg, Meret Emily Schmid, Sofia Zahia, Sebastian Probst et al. (Switzerland, Australia, Ireland, Italy - JCM).
The data suggest that this wound-halving algorithm is suitable and reliable for conducting wound studies. This innovative combination of a semi-automated algorithm paired with a unique study design offers several advantages, including reduced patient recruitment needs, accelerated study planning, and cost savings, thereby expediting evidence generation in the field of wound care.
Eco-Friendly Production of Polyvinyl Alcohol/Carboxymethyl Cellulose Wound Healing Dressing Containing Sericin - Mdpi.com
Article by Massimo Mariello, Enrico Binetti, Maria Teresa Todaro, Antonio Qualtieri et al. (Lecce, Italy - Gels).
The proposed hydrogel dressing was tested in vitro with HaCaT keratinocytes and ex vivo with epidermal tissues, demonstrating an effective advantage on wound healing acceleration.
Negative Pressure Wound Therapy for Chronic Wounds - PubMed
Abstract by Wenbo Li and Jianghong Zheng (Shanghai, China - Ann Plast Surg.).
The risk factors in diabetic foot ulcers and predictive value of prognosis of wound tissue vascular endothelium growth factor - Nature.com
Article by Jing Xu, Jian Gao, Hui Li, Zhoujun Zhu, Junliang Liu and Chong Gao (China - Scientific Reports).
Diabetes mellitus duration, FPG, HbA1c, ABI, serum VEGF, VEGF in wound tissue, and positive rate of VEGF expression are the independent risk factors for prognosis in DFU patients. Patients with these risk factors should be screened in time, which is of great significance to prevent DFU related adverse events and improve outcomes.
Use of Split-Thickness Skin Grafts and Autologous Skin Cell Suspension in a Case of Extensive Fournier Gangrene - Cureus.com
Article by Connor J. English, Oluwafolaranmi E. Sodade, Cindy L. Austin and Krisi A. Causa (USA).
Autologous skin cell suspension technology has been used in addition to split-thickness skin grafting (STSG) to provide better wound healing and closure. This patient experienced excellent wound progression, following Fournier gangrene, through the application of ASCS with STSG, despite challenges related to the wounds, anatomical location, comorbidities, size, and the patient’s medical history.
Advances in Chronic Wound Management: From Conventional Treatment to Novel Therapies and Biological Dressings - PubMed
Abstract by Anisa Andleeb, Hamza Khan, Aneeta Andleeb, Maria Khan and Muhammad Tariq (Pakistan - Crit Rev Biomed Eng.).
Wound management materials and technologies from bench to bedside and beyond - Nature.com
Abstract by Canran Wang, Ehsan Shirzaei Sani, Chia-Ding Shih, Chwee Teck Lim et al. (USA - Nature Reviews Materials).
Researchers develop cutting-edge smart bandages for improved wound healing - News-medical.net
A team of researchers from the Keck School of Medicine of USC and the California Institute of Technology (Caltech) is developing a series of cutting-edge technologies to revolutionize wound care, including smart bandages that would automatically sense and respond to changing conditions inside a wound. These high-tech dressings would provide continuous data on healing and potential complications, including infections or abnormal inflammation, and could deliver medications or other treatments in real time.
Comparing Wound Healing and Infection Risk Between Early and Late Dressing Removal After Abdominal Hysterectomy - Cureus.com
Article by Emrullah Akay, Kübra Irmak, Ravza Incebıyık, Fatma Sağlam and Enes Burak Mutlu (Turkey).
Early dressing removal after abdominal hysterectomy was observed to positively affect wound healing and facilitate earlier hospital discharge. However, no significant differences were found in hospital readmission rates between the two groups.
Adipose-Derived Stem Cell Exosomes Facilitate Diabetic Wound Healing: Mechanisms and Potential Applications - Dovepress.com
Article by Kang Wang, Zihui Yang, Boyu Zhang, Song Gong and Yiping Wu (Wuhan, China - International Journal of Nanomedicine).
A thorough understanding of these molecular mechanisms and potential applications is anticipated to furnish a theoretical groundwork for combating diabetic wound healing.
Impact of oral nutritional supplement composition on healing of different chronic wounds: A systematic review - PubMed
Abstract by Allan Carlos Soares do Espírito Santo, Clara Sandra de Araújo Sugizaki, Alcides Corrêa de Morais Junior, Nara Aline Costa et al. (Goiânia, Brazil - Nutrition).
Nutrition Support for Older Adults With Pressure Injuries Receiving Maintenance Hemodialysis: A Case Study - PubMed
Abstract by Julius S Navarro and Rebecca Brody (USA - J Ren Nutr.).
How Might Climate Impact Chronic Wounds? - Woundsource.com
When pondering the multitude of considerations that go into treating chronic wounds, climate is not likely one of the first factors that comes to mind. However, in their track at WoundCon Summer, Maria Goddard and Laura Swoboda highlighted climate-related concerns that could be impacting your patients.
Phlebolymphedema Foundations for Wound Care Professionals - Woundsource.com
At WoundCon Summer, Frank Aviles, Jr. shared what providers need to know about phlebolymphedema, a condition resulting from concurrently impaired venous and lymphatic systems. In order to better understand this pathology, one must also understand its individual components and characteristics.
A bioelectronic device for electric field treatment of wounds reduces inflammation in an in vivo mouse model - Plos.org
Article by Cristian O. Hernandez, Hao-Chieh Hsieh, Kan Zhu, Houpu Li et al. (USA - Plos One).
The authors' wearable device supports the rationale for the application of programmed electric fields for wound management in vivo and provides an exciting basis for further development of our technology based on the modulation of macrophages and inflammation to better wound healing.
Hydrogel Wound Dressings Accelerating Healing Process of Wounds in Movable Parts - Mdpi.com
Article by Pengcheng Yu, Liqi Wei, Zhiqi Yang, Xin Liu et al. (Changchun, China - IJMS).
The authors focus on the recent advances in hydrogel-based movable wound dressings and propose the challenges and perspectives of such dressings.
The utility of negative pressure wound therapy in the management of complex deep cardiothoracic surgical site infections - PubMed
Abstract by Yasser Aljehani, Farouk Alrashaid, Hatem El-Bawab, Naif Alkhaldi et al. (Dammam, Saudi Arabia - Wounds).
Offloading Options Clinicians Should Know When Managing Diabetic Foot Ulcers - Woundsource.com
Article by Roshni Gandhi Patel.
Diabetic foot ulcers (DFU) pose significant challenges in clinical management, often requiring effective offloading strategies to promote healing and prevent complications. With the 2023 International Working Group on the Diabetic Foot (IWGDF) guidelines as a reference point, this article delves into various essential offloading options clinicians should know.
The Development of the Available Technology Dressing, an Evidence-Based, Sustainable Solution for Wound Management in Low-Resource Settings - Hmpgloballearningnetwork.com
Article by Linda Benskin and Richard Benskin.
This study demonstrated that the proposed Available Technology Dressings (ATD) concept is sound. All materials (the irrigation device, periwound protectant, primary dressing, absorbent, and wrap) should be chosen for their functional properties and be readily available (which implies affordability) in the setting of the learners. Because the technique must be rigorously followed for the dressing to provide optimal benefits while minimizing risk of complications, the reason for each aspect of the dressing technique must be taught.
Neuroimmunomodulatory effect of Nitric Oxide on chronic wound healing after photodynamic therapy - Sciencedirect.com
Article by Patrizia Nardini, Lorenzo Notari, Miriam Magazzini, Bianca Mariani et al. (Italy, UK - Photodiagnosis and Photodynamic Therapy).
The significance of photodynamic therapy in enhancing the clinical condition of the lesion is highlighted.
The scientific study of herbal wound healing therapies: Current state of play - Sciencedirect.com
Abstract by P. Krishnan (Stockton-on-Tees, UK - Current Anaesthesia & Critical Care).
Hypoxic environment of wounds and photosynthesis-based oxygen therapy - Nig.gov
Article by Shuning Tian, Shenyu Tan, Mingjie Fan, Wenlin Gong, Tianchang Yang et al. (Nanjing, China - Burns & Trauma).
In this paper, oxygen treatment methods for wounds are reviewed, and the oxygen supply principle and construction of artificial photosynthesis systems are described.
Peceleganan Spray for the Treatment of Skin Wound Infections. A Randomized Clinical Trial - Jamanetwork.com
Article by Yating Wei, Yi Li, Xiaojian Li, Yaohua Zhao et al. (China - JAMA Network Open).
This randomized clinical trial found that peceleganan spray is a safe topical antimicrobial agent with a satisfactory clinical efficacy rate for the treatment of skin wound infections, while the effectiveness of bacterial clearance remains uncertain.
ER-mitochondria association negatively affects wound healing by regulating NLRP3 activation - Nature.com
Article by Caterina Licini, Gianluca Morroni, Guendalina Lucarini, Veronica Angela Maria Vitto et al. (Italy - Cell Death & Disease).
These results identify the ER-mitochondria association as a key factor for NLRP3 activation and reveal a new mechanism in the regulation of the wound healing process that might be clinically relevant.
Regulation of the Degradation Properties of Tyrosinase-Catalyzed Crosslinking Silk Membranes for Superficial Wound Repair - Mdpi.com
Article by Yu Liu, Xuping Liu, Yuhong Jiao and Mingzhong Li (Suzhou, China - Materials).
This work provides a new c-SF membrane with controllable rapid degradability and favorable cytocompatibility, which can help to meet requirements for biodegradable superficial wound repair membranes.
Improving the Care and Cost of Treating Community-Acquired Stage 3 and 4 Decubitus Ulcers - PubMed
Abstract by Paulina B Le, Joseph Kelly-Brown, Kylee J Yturralde, Donna J McGreevy et al. (Columbia, USA - Ann Plast Surg.).
Synergetic Antibacterial Nanoparticles with Broad-Spectrum for Wound Healing and Lung Infection Therapy - Wiley.com
Article by Lei Guo, Yixin Tang, Lu Wang, Rui Zhou, Siyuan Wang et al. (Changchun, China - Advanced Function Materials).
This study provides a new strategy for designing a synergetic anti-antimicrobial resistance (AMR) bacteria system and the function for deep tissue/organ infection therapy in the future.
A Prospective Study of Sutured Versus Non-sutured Subcutaneous Fat Tissue in Laparotomy Wound Closure - Cureus.com
Article by Jasira Padinhare Madathil, Revathy P. Kumar, T. V. Haridas, Jim Job et al. (UK, India).
Subcutaneous suturing during elective laparotomy wound closure significantly reduced superficial surgical site infection, hematoma, seroma, and total wound dehiscence; in the remaining categories, subcutaneous and non-subcutaneous sutures did not differ significantly. It also did not help to reduce hospital stays.
Research Perspectives on Quality of Life in Wound Care Patients - Wiley.com
Caroline Fife and Marissa Carter discuss their research into the numerous medical problems that patients with chronic wounds and ulcers have, and how this can impact their quality of life.
The rat as an animal model in chronic wound research: An update - PubMed
Abstract by Mahboubeh Ghanbari, Yury Salkovskiy and Mark A Carlson (Omaha, USA - Life Sci.).
A Closer Look at Venous Leg Ulcers and Chronic Venous Insufficiency in Over One Million Medicare Enrollees - Wiley.com
Approximately 70% of chronic lower extremity wounds diagnosed every year in the United States are identified as venous leg ulcers (VLUs). VLUs and, by extension, chronic venous insufficiency are growing concerns for wound care professionals. As such, it is vital to stay up to date on recent literature published on this condition's impact and management, with an eye towards improving practices and outcomes to break the cycle of ulceration, infection, and remission.
Antimicrobial photodynamic therapy with methylene blue and its derivatives in animal studies: Systematic review - PubMed
Abstract by Ana Paula Martin Cardozo, Daniela de Fátima Teixeira da Silva, Kristianne Porta Santos Fernandes, Rita de Cassia Ferreira et al. (São Paulo, Brazil - Photodermatol Photoimmunol Photomed.).
Analysis of Current Trends in Angiogenesis Research for Wound Healing: A Bibliometric Study from 2013 to 2023 - Sciencedirect.com
Article by Miao Wang, Cheng Xu, Di Wang, Jie Lu et al. (Shanghai, China - Heliyon).
In this investigation, authors compiled the features of publications and determined the most impactful nations, organizations, writers, periodicals, popular subjects, and patterns concerning the process of angiogenesis in the context of wound healing.
Interventions for postburn pruritus - PubMed
Abstract by Sarthak Sinha, Vincent A Gabriel, Rohit K Arora, Wisoo Shin et al. (Canada, USA, India - Cochrane Database Syst Rev.).
Recent advances in molecular mechanisms of skin wound healing and its treatments - PubMed
Abstract by Abdullah Al Mamun, Chuxiao Shao, Peiwu Geng et al. (China - Front Immunol.).
A Multifunctional Dressing for Effective Wound Care in Home Health - Woundsource.com
Home care can pose unique challenges, which Judy Burbage, poster author from SAWC Spring shares potential solutions for in this interview.
Edema Insights for Wound Care Professionals - Woundsource.com
Learn more from these experts in this special episode of Speaking of Wounds. Discussion topics include comorbidities, compression therapy, patient-specific scenarios to consider.
Tunneling Wound Assessment and Treatment - Woundsource.com
Perhaps the most difficult type of wound for health care professionals to treat is a tunneling wound. Tunneling wounds require careful wound assessment and management. This blog covers the causes, assessment and management of these wounds.
An exploratory randomized clinical trial on negative pressure wound therapy for lower limb full-thickness skin grafts of dermatosurgical patients - Wiley.com
Article by Vivian Mikaela Lindholm, Anna Wilhelmina Salminen, Sari Johanna Koskenmies, Mari Kaarina Salmivuori et al. (Helsinki, Finland - International Wound Journal).
The study showed no benefit from NPWT for lower limb full-thickness skin grafts.
A systematic review on the impact of sub-epidermal moisture assessments on pressure ulcer/injury care delivery pathways - Wiley.com
Article by Pinar Avsar, Declan Patton, Janet Cuddigan and Zena Moore (Ireland, USA, UK - International Wound Journal).
The authors' findings emphasise the importance of incorporating SEM assessments as part of comprehensive PI/PU prevention strategies in all care settings and patient populations.
Instantly adhesive and ultra-elastic patches for dynamic organ and wound repairs - Nature.com
Article by Parth Chansoria, Ameya Chaudhari, Emma L. Etter, Emily E. Bonacquisti et al. (Chapel Hill, USA - Nature Communications).
Patches coated with extracellular vesicles derived from mesenchymal stem cells demonstrate robust wound healing capability in vivo without inducing a foreign body response and without the need for patch removal that can cause pain and bleeding.
Perioperative corticosteroids for preventing complications following facial plastic surgery - Nih.gov
Article by Edina MK da Silva, Bernardo Hochman, Lydia M Ferreira and Cochrane Wounds Group (São Paulo, Brazil - Cochrane Database Syst Rev.).
The current evidence does not support use of corticosteroids as a routine treatment in facial plastic surgery. More trials will need to be conducted before it can be established whether this treatment works and is safe.
Biopolymers Take Center Stage in Wound Healing Advancements - Mdpi.com
Article by Gorka Orive and Martín Federico Desimone (Spain, Argentina - Pharmaceutics).
Biopolymers, as naturally occurring polymers derived from biological sources, offer unique advantages for wound healing applications. Their biocompatibility, biodegradability, and structural versatility make them ideal candidates for developing novel wound dressings, drug delivery systems, and tissue engineering scaffolds. Scientific research underscores the exciting possibilities of natural polymers in the field of biomedicine.
Flexible, biodegradable ultrasonic wireless electrotherapy device based on highly self-aligned piezoelectric biofilms - Science.org
Article by Haoyue Xue, Jing Jin, Zhi Tan, Keliang Chen et al. (Chengdu - Science Advances).
The authors' encouraging results offer reliable approaches for engineering piezoelectric biofilms and developing transient bioelectronics.
Enhanced Skin Assessment Methodology to Detect Early Tissue Damage and Prevent Pressure Injuries - PubMed
Abstract by Joyce Pittman, Jo Ann Otts and Madhuri Mulekar (Alabama, USA - J Wound Ostomy Continence Nurs.).
The effects of wearing textured versus smooth shoe insoles for 4-weeks in people with diabetic peripheral neuropathy: a randomised controlled trial - PubMed
Abstract by Anna L Hatton, Mark D Chatfield, Elise M Gane, Jayishni N Maharaj et al. (Australia, UK, New Zealand - Disabil Rehabil.)
A Prospective, Open-Label, Nonrandomized Clinical Trial Using Polyvinyl Alcohol Antibacterial Foam for Debridement of Diabetic Foot Ulcers - Hmpgloballearningnetwork.com
Article by Eric Lullove (Coconut Creek, USA - Wounds).
The findings suggest that PVA GV/MB foam dressings, when combined with surgical debridement, are effective in promoting the healing of chronic diabetic foot ulcers.
Monitoring the Effect of Continuous Topical Oxygen Therapy With Near-Infrared Spectroscopy: A Pilot Case Series in Wound Healing - Hmpgloballearningnetwork.com
Article by Windy Cole and Emma Woodmansey (USA, UK - Wounds).
This case series reinforces previous studies that cTOT is an effective, noninvasive treatment as a key adjunct to standard care in nonhealing wounds. Moreover, point-of-care tools such as the NIRS imaging device provided objective information concerning tissue oxygenation improvements, thus giving useful insights to the clinician.
Quality of life case series review: wound bed preparation from a UK perspective - PubMed
Abstract by Priti Bhatt (London, UK - Br J Community Nurs.).
The Efficacy of Local Autologous Platelet-Rich Plasma Prepared by Single and Double Spin Methods in the Treatment of Chronic Ulcer - Cureus.com
Article by Devesh Dubey and Babita Raghuwansh (Bhopal, India).
The single spin platelet-rich plasma method exhibited considerable improvements in healing parameters, showcasing its potential for chronic ulcer management.
Preparation of the Wound Bed of the Diabetic Foot Ulcer - Springer.com
Abstract by Kevin Riemer and Kevin Buczkowski (USA - The Diabetic Foot).
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