Advanced Treatment Options of Pyoderma Gangrenosum Ulcers - Woundresearch.com
Article by Danijela Semenič and Petra Bukovec. Pyoderma gangrenosum (PG) is a neutrophilic dermatosis often associated with autoimmune disease that, despite published literature, still poses diagnostic and therapeutic challenges due to its lack of serological and histological markers and wide possibility of differential diagnosis.
Mesenchymal Stem Cells Adaptively Respond to Environmental Cues Thereby Improving Granulation Tissue Formation and Wound Healing - Frontiersin.org
Article by Dongsheng Jiang and Karin Scharffetter-Kochanek (Germany). Granulation tissue formation constitutes a key step during wound healing of the skin and other organs. Granulation tissue concomitantly initiates regenerative M2 macrophages polarization, fibroblast proliferation, myofibroblast differentiation with subsequent contraction of the wound, new vessel formation, and matrix deposition.
The knowledge of pressure ulcer among nursing students and related factors - Nih.gov
Abstract by Sarmilan Murugiah, Kosheila Ramuni, Urmisha Das, Hafizah Che Hassan and Sevender Khor Bibi Florina Abdullah (Malaysia - Enferm Clin.).
Living with leg lymphedema: developing a novel model of quality lymphedema care for cancer survivors - Nih.gov
Abstract by Catharine Bowman, Devesh Oberoi, Lori Radke, George J Francis and Linda E Carlson (Calgary, Canada - J Cancer Surviv.).
pdf (1,78 mB)!
Bioinspired Materials for Wound Healing Application: The Potential of Silk Fibroin - Mdpi.com
Article by Mauro Pollini and Federica Paladini (Lecce, Italy - Materials). Nature is an incredible source of inspiration for scientific research due to the multiple
examples of sophisticated structures and architectures which have evolved for billions of years in different environments. Numerous biomaterials have evolved toward high level functions and performances, which can be exploited for designing novel biomedical devices.
Step-up approach combined with negative pressure wound therapy for the treatment of severe necrotizing pancreatitis: a case report - Nih.gov
Abstract by Yosuke Namba, Yasuhiro Matsugu, Masaru Furukawa, Maiko Namba, Tamito Sasaki and Toshiyuki Itamoto (Hiroshima, Japan - Clin J Gastroenterol.).
Pharmacological activation of Nrf2 promotes wound healing - Nih.gov
Abstract by Paul Victor, Dronamraju Sarada and Kunka Mohanram Ramkumar (Chennai, India - Eur J Pharmacol.).
The use of negative-pressure wound therapy after total knee arthroplasty is effective for reducing complications and the need for reintervention - Nih.gov
Abstract by Camilo Partezani Helito, Marcel Faraco Sobrado, Pedro Nogueira Giglio, Marcelo Batista Bonadio, José Ricardo Pécora, Marco Kawamura Demange and Riccardo Gomes Gobbi (São Paulo, Brazil - BMC Musculoskelet Disord.).
New Insights into the Pathophysiology of Primary and Secondary Lymphedema: Histopathological Studies on Human Lymphatic Collecting Vessels - Nih.gov
Abstract by Virginia Barone, Annalisa Borghini, Erica Tedone Clemente, Margherita Aglianò, Guido Gabriele, Paolo Gennaro and Elisabetta Weber (Siena, Italy - Lymphat Res Biol.).
Functional Mining of the Crotalus Spp. Venom Protease Repertoire Reveals Potential for Chronic Wound Therapeutics - Mdpi.com
Article by David Meléndez-Martínez, Luis Fernando Plenge-Tellechea, Ana Gatica-Colima, Martha Sandra Cruz-Pérez, José Manuel Aguilar-Yáñez and Cuauhtémoc Licona-Cassani (Mexico - Molecules).
The authors' results demonstrated the presence of metalloproteases capable of degrading gelatin (a collagen derivative) and fibrin clots, whereas serine proteases were capable of degrading fibrinogen-generating fibrin clots, mimicking thrombin activity. Moreover, they demonstrated that Crotalus spp. are a valuable source of proteases that can aid chronic wound-healing treatments.
Novel biophysical marker enables detection of pressure wounds five days earlier than visual skin assessment - Iwoundsnews.com
Preliminary evidence supports the use of a novel biophysical marker—the measurement of sub-epidermal moisture—to detect tissue damage early, allowing wound care specialists to identify pressure/shear-induced tissue damage and intervene “when the damage is still microscopic and reversible”.
Predictors of Surgical Site Infections Among Patients With Diabetes Mellitus Post Coronary Artery Bypass Graft Surgery: A Quasi-experimental Study - Woundresearch.com
Article by Audai A. Hayajneh, Issa M. Hweidi and Ala M. Zytoon. Three key factors were found to predict the occurrence of SSIs in patients with DM undergoing CABG. These findings underscore the necessity for health care providers to adhere to and employ meticulous infection control practices when managing at-risk CABG patients.
Liposuction Treatment of a Subacute Morel-Lavallée Lesion: A Case Report - Woundresearch.com
Article by Shana S. Kalaria, Alexis Boson and Lance W. Griffin. This case of MLL was diagnosed early and successfully treated with liposuction, resulting in an acceptable cosmetic outcome. It is the authors’ hope that this case report will lead to earlier diagnosis and proper treatment of MLLs.
Successful treatment of enterocutaneous fistula after esophagectomy with scopolamine ointment and negative pressure wound therapy: a case report - Nih.gov
Abstract by Shigemasa Suzuki, Ryusuke Aihara, Takashi Ooki, Naoki Matsumura, Wataru Wada, Akira Mogi, Yasuo Hosouchi, Yasuji Nishida, Makoto Sakai, Makoto Sohda, Hiroshi Saeki and Ken Shirabe (Maebashi, Japan - Surg Case Rep.).
Development of the spinal cord injury pressure sore onset risk screening (SCI-PreSORS) instrument: a pressure injury risk decision tree for spinal cord injury rehabilitation - Nih.gov
Abstract by Jude J Delparte, Heather M Flett, Carol Y Scovil and Anthony S Burns (Toronto, Canada - Spinal Cord).
Shoelace Technique Plus Negative-Pressure Wound Therapy Closure in Fasciotomy Wounds - Nih.gov
Abstract by Engin Eceviz and Hüseyin Bilgehan Çevik (Turkey - Adv Skin Wound Care).
First-ever research network tackles diabetic foot complications - Nih.gov
Funded by the National Institutes of Health, six U.S. research institutions are launching the first-ever multicenter network to study diabetic foot ulcers, a common and burdensome complication of diabetes and the leading cause of lower limb amputations in the United States.
Long non-coding RNA H19 contributes to wound healing of diabetic foot ulcer - Nih.gov
Abstract by Bo Li, Yue Zhou, Jing Chen, Tingting Wang, Zhijuan Li, Yili Fu, Changlong Bi and Aixia Zhai (China - J Mol Endocrinol.).
Innovative Bioactive Glass Fiber Technology Accelerates Wound Healing and Minimizes Costs: A Case Series - Nih.gov
Abstract by Donald W Buck 2nd (St. Louis, USA - Adv Skin Wound Care.).
Application and nursing effect analysis of negative pressure wound therapy combined with drip irrigation in the treatment of diabetic refractory wounds - Nih.gov
Abstract by Yaping Peng, Hongyan Shen, Ke Li, Xiu Cheng and Zhiying Zhao (Suzhou, China - Minerva Med.).
The infected diabetic foot: Can serum biomarkers predict osteomyelitis after hospital discharge for diabetic foot infections? - Nih.gov
Abstract by Peter Andrew Crisologo, Kathryn E Davis, Junho Ahn, David Farrar, Suzanne Van Asten, Javier La Fontaine and Lawrence A Lavery (Dallas, USA - Wound Repair Regen.).
The ‘Gold Standard’ of Diabetic Peripheral Neuropathy Testing - Todayswoundcilinic.com
Article by Jaclyn Gaydos. Although it is debatable today, the Semmes-Weinstein Monofilament Examination (SWME) is considered to be the gold standard for first-line screening of diabetic peripheral
neuropathy in the feet.
The Efficacy of Five Different Wound Dressings on Some Histological Parameters in Children With Partial-Thickness Burns - Oup.com
Abstract by Birsen Harma, Mehmet Gül and Mehmet Demircan (Malatya, Turkey - Journal of Burn Care & Research).
Cold Plasma Speeds Diabetic Ulcer Healing - Medpagetoday.com
Article by Kristen Monaco. Eight applications were added to standard wound care in randomized study.
Effect of Novel Anteromedial Approach on Wound Complications Following Ankle Arthroplasty - Nih.gov
Abstract by Mansur M Halai, Ellie Pinsker and Timothy R Daniels (Toronto, Canada - Foot Ankle Int.).
Acidified nitrite improves wound healing in type 2 diabetic rats: Role of oxidative stress and inflammation - Nih.gov
Abstract by Hamideh Afzali, Mohammad Khaksari, Reza Norouzirad, Sajad Jeddi, Khosrow Kashfi and Asghar Ghasemi (Iran, USA - Nitric Oxide.).
Delayed Wound Healing: Investigating and Addressing the Cause - Wounsource.com
Article by Janet Wolfson. Delayed wound healing: how did it start, what are we doing to prevent delay, and what could we be doing differently when delay is noted?
Sub-epidermal moisture measurement: an evidence-based approach to the assessment for early evidence of pressure ulcer presence - Nih.gov
Abstract by Aglecia Moda Vitoriano Budri, Zena Moore, Declan Patton, Tom O'Connor, Linda Nugent and Pinar Avsar (Dublin, Ireland - Int Wound J.).
Vacuum-Assisted Closure Therapy for the Treatment of Poststernotomy Wound Dehiscence in Neonates and Infants - Nih.gov
Abstract by Federico Lo Torto, Gianmarco Turriziani, Fabio Miraldi, Bruno Carlesimo and Diego Ribuffo (Roma, Italy - Thorac Cardiovasc Surg.)
The Use of Closed Incision Negative Pressure Therapy Immediately After Total Ankle Arthroplasty Surgeries - Nih.gov
Abstract by Alexandra Sidorski and Gregory Lundeen (Reno, USA - Cureus)
pdf (4,84 mB)!
Enhancement of Skin Wound Healing by rhEGF-Loaded Carboxymethyl Chitosan Nanoparticles - Mdpi.com
Article by Pei Zhang and Chenguang Liu (China - Polymers). Topically applied rhEGF:CC-NPs significantly accelerated the wound-closure rate in full thickness,
which was most probably due to its sustained release and enhanced skin permeation. In conclusion, carboxymethyl chitosan-based nanoparticles were constructed and showed good cytocompatibility. Moreover, these findings also demonstrated the therapeutic potential of rhEGF:CC-NPs as a topical wound-healing drug carrier.
Treatment of Hard-to-heal Diabetic Foot Ulcers With a Hepatic-derived Wound Matrix - Woundresearch.com
Article by Robert Fridman, Payam Rafat, Carl C. Van Gils, Deena Horn, Dean Vayser and C. Jake Lambert, Jr.
This study evaluates the ability of a novel hepatic-derived wound matrix (HD-WM) to treat hard-to-heal DFUs.
Current Concepts of Non-Traumatic Foot Amputation: Indications and Aftercare - Todayswoundcilinic.com
Article by Kazu Suzuki and Tiffany M. Chin. Which level of amputation is appropriate for patients with diabetes? These authors review considerations when patients need non-traumatic amputation, including surgical indications and how to help patients
function best postoperatively.
A novel multifaceted approach for wound healing: optimization and in vivo evaluation of spray dried tadalafil loaded pro-nanoliposomal powder - Nih.gov
Abstract by Jana K Alwattar, Racha Chouaib, Alia Khalil and Mohammed M Mehanna (Lebanon, Egypt - Int J Pharm.)
Novel Application of Immunomodulatory Mushroom Polysaccharide (β-Glucan) and Triterpenes for Diabetic Wound Care - Intechopen.com
Article by Shiu-Nan Chen, Yu-Sheng Wu, Sherwin Chen, Ya-Chin Chang and Chung-Lun Lu.
Difficulty in healing wound now is a common condition that occurred in diabetic patients, and the physiological hyperglycemic status of diabetic patients resulting in the wounds continue to produce an inflammatory response. Thus, the authors hope to use β-glucan and triterpenes for difficult wound healing that possess immunomodulatory activity on the wound micro-environment and stimulate the positive effects on healing.
Evaluation of Botulium toxin type A for treating hypertrophic scars: A split-scar, double-blind randomized controlled trial - Nih.gov
Abstract by Ahmad R Elshahed, Khaled S Elmanzalawy, Hany Shehata and Mohamed L ElSaie (Egypt - J Cosmet Dermatol.)
Curcumin preconditioned human adipose derived stem cells co-transplanted with platelet rich plasma improve wound healing in diabetic rats - Nih.gov
Abstract by Hafiz Ghufran, Azra Mehmood, Maryam Azam, Hira Butt, Amna Ramzan, Muhammad Amin Yousaf, Asim Ejaz, Moazzam N Tarar and Sheikh Riazuddin (Pakistan, USA - Life Sci.)
New treatment for chronic wounds using CO2 lasers - Medicalxpress.com
Chronic wound repair can be a major problem in wound treatment. Recently, several studies have suggested that carbon dioxide (CO2) laser can be used to improve the healing of chronic wounds. This study investigates the efficacy of laser debridement to treat chronic wounds using a comparison of traditional surgical debridement and ultrapulsed CO2 laser debridement.
3-D Skin Bioprinting: The Future for Wound Healing? - Dermatologyadvisor.com
Article by Tori Rodriquez. Although prevention strategies have reduced the incidence of serious burns since the 20th century, burns remain a leading cause of trauma worldwide. Each year, more than 11 million people globally and 1 million people in the United States require medical treatment for burns. Other types of chronic wounds, such as diabetic and pressure ulcers, also affect a substantial number
of Americans.
Development and validation of an ICU-specific pressure injury risk assessment scale - Nih.gov
Abstract by Ingrid Wåhlin, Anna-Christina Ek, Margareta Lindgren, Sebastian Geijer and Kristofer Årestedt (Sweden - Scand J Caring Sci.).
Preparation of aminated fish scale collagen and oxidized sodium alginate hybrid hydrogel for enhanced full-thickness wound healing - Nih.gov
Abstract by Xiaolian Feng, Xiaofang Zhang, Shiqi Li, Yunquan Zheng, Xianai Shi, Feng Li, Shaobin Guo and Jianmin Yang (Fuzhou, China - Int J Biol Macromol.).
Negative Pressure Wound Therapy in children: A 25 cases series - Nih.gov
Abstract by L Pouzet, U Lancien, A Hamel, P Perrot and F Duteille (France - Ann Chir Plast Esthet.).
A modified negative pressure wound therapy for the treatment of refractory wounds: A preliminary study - Nih.gov
Abstract by Dong Xing, Zhaoxu Yang, Can Cao, Zhijie Dong, Jingchao Wei, Xuehong Zheng and Wenyi Li (Shijiazhuang, China - Medicine (Baltimore)).
Prolactin may serve as a regulator to promote vocal fold wound healing - Portlandpress.com
Downloadable arcticle by Haizhou Wang, Xueyan Li, Jieyu Lu, Paul Jones and Wen Xu (China, USA - Biosci. Rep.).
Reduced prolactin (PRL) has been shown to delay wound healing with a limited understanding of the underlying mechanisms. Here, the authors aim to explore the role of PRL in the repair of vocal fold (VF) injury.
Alginate/human elastin-like polypeptide composite films with antioxidant properties for potential wound healing application - Sciencedirect.com
Abstract by Carlo Bergonzi, Giovanna Gomez d'Ayala, Lisa Elviria Paola Laurienzo, Antonella Bandiera and Ovidio Catanzano (Italy - International Journal of Biological Macromolecules).
Diabetic Wound Management in Long-Term Care - Seniornews.com
Caring for a wound is important for people of any age, but for diabetics, and especially seniors it’s crucial. Older patients living in long term care facilities are often not physically active, and some are completely bed bound. According to the American Diabetes Association (ADA), long term care facilities are host to a
larger number of seniors dealing with diabetes.
Targeted inhibition of endothelial calpain delays wound healing by reducing inflammation and angiogenesis - Nature.com
Article by Chenlong Yi, Weihua Wu, Dong Zheng, Guangying Peng, Haoyue Huang, Zhenya Shen and Xiaomei Teng (Suzhou, China).
Wound healing is a multistep phenomenon that relies on complex interactions between various cell types. Calpains are a well-known family of calcium-dependent cysteine proteases that regulate several processes, including cellular adhesion, proliferation, and migration,
as well as inflammation and angiogenesis.
Extracellular vesicle‐enclosed miR‐486‐5p mediates wound healing with adipose‐derived stem cells by promoting angiogenesis - Wiley.com
Article by Yingjie Lu, Huicai Wen, Jinjun Huang, Peng Liao, Huaiwei Liao, Jun Tu and Yuanlin Zeng (Journal of Cellular and Molecular Medicine). Adipose‐derived stem cells (ASC) are said to have a pivotal role in wound healing. Specifically, ASC‐secreted extracellular vesicles (EV) carry diverse cargos such as microRNAs (miRNAs)
to participate in the ASC‐based therapies.
In vitro evaluation of antioxidant and antibacterial activities of eucheuma cottonii extract and its in vivo evaluation of the wound healing activity in mice - Nih.gov
Abstract by Brian Sheng Xian Teo, Rui Yi Gan, Sarah Abdul Aziz, Thanchanok Sirirak, Mohd Fadli Mohd Asmani and Eddy Yusuf (Malaysia, Thailand - J Cosmet Dermatol.).
The impact of non-toxic blue light (453 nm) on cellular antioxidative capacity, TGF-β1 signaling, and myofibrogenesis of human skin fibroblasts - Nih.gov
Abstract by Julia M Krassovka, Christoph V Suschek, Max Prost, Vera Grotheer, Jennifer L Schiefer, Erhan Demir, Paul C Fuchs, Joachim Windolf, Ewa K Stürmer and Christian Opländer (Germany - J Photochem Photobiol B.).
Prospective, Single-center, Open-label, Pilot Study Using Cryopreserved Umbilical Tissue Containing Viable Cells in the Treatment of Complex Acute and Chronic Wounds - Woundresearch.com
Article by Robert F. Mullins, Zaheed Hassan, Bounthavy Homsombath, Shawn Fagan, Beretta Craft-Coffman, Joan Wilson, John G. Rumbaugh, Molly C. Saunders and Alla Danilkovitch (USA). Complex wounds with exposed bone, muscle, tendon, or hardware continue to be a therapeutic challenge for wound care providers. Wounds with exposed structures are more susceptible to infection, necrosis,
and amputation.
Clinical Evaluation of Scar Quality Following the Use of Prophylactic Negative Pressure Wound Therapy in Obese Women Undergoing Cesarean Delivery: A Trial-Based Scar Evaluation - Nih.gov
Abstract by Nana Hyldig, Sören Möller, Jan Stener Joergensen and Camilla Bille (Odense, Denmark - Ann Plast Surg.).
Silver nanocomposites based on the bacterial fucose-rich polysaccharide secreted by Enterobacter A47 for wound dressing applications: Synthesis, characterization and in vitro bioactivity - Nih.gov
Abstract by Patrícia Concórdio-Reis, Carolina V Pereira, Miguel P Batista, Chantal Sevrin, Christian Grandfils, Ana C Marques, Elvira Fortunato, Frédéric B Gaspar, Ana A Matias, Filomena Freitas and Maria A M Reis (Portugal, Belgium - Int J Biol Macromol.).
Treatment of hard-to-heal leg ulcers with hyaluronic acid, sodium alginate and negative pressure wound therapy - Nih.gov
Abstract by Omer Arda Cetinkaya, Suleyman Utku Celik, Can Yahya Boztug and Hakan Uncu (Ankara, Turkey - J Wound Care).
The Impact of Restoring Flow in Order to Preserve Limbs - Todayswoundcilinic.com
Article by Desmond Bell. When trying to prevent lower extremity amputation, it is critical that wound clinicians restore blood flow in a quick and aggressive fashion. This author offers a historic perspective of advances in endovascular technologies and how they can save limbs.
Fighting Peripheral Arterial Disease One Leg at a Time - Todayswoundcilinic.com
Article by Caroline E. Fife. To prevent amputation by screening for and treating peripheral arterial disease, this author notes CMS quality measures can aid clinicians in doing the right thing.
Electromedical devices in wound healing management: a narrative review - Magonlinelibrary.com
Abstract by Beniamino Palmieri, Maria Vadalà and Carmen Laurino. The review focuses on the evidence-based medicine and adequate clinical trial design in relation to these devices.
The Risk of Infection and Indication of Systemic Antibiotics in Chronic Wounds - Woundresearch.com
Article by Rachel L. Reitan, Robert M. McBroom and Richard E. Gilder. This evidence-based practice project aims to identify both chronic wounds at risk for infection and the risk factors associated with chronic wound infection, evaluate the use of systemic antibiotics in patients with chronic wounds, and reduce the use of systemic antibiotics in chronic wounds that are not infected or at risk for infection by implementing a Wounds at Risk (WAR) score for all patients admitted with chronic wounds.
A Literature Review of Pharmacological Agents to Improve Venous Leg Ulcer Healing - Woundresearch.com
Article by Brandon P. Kitchens, Robert J. Snyder and Cherison Cuffy. Venous leg ulcers (VLUs), or varicose ulcers, are the final stage of chronic venous insufficiency (CVI) and are the most common type of leg ulcer. The development of VLUs on distal legs and ankles can occur
after minor trauma or spontaneously.
Lotus Leaf Inspired Antiadhesive and Antibacterial Gauze for Enhanced Infected Dermal Wound Regeneration - Sciencedirect.com
Abstract by Shengyu Lia, Anqi Chen, Yanxin Chena, Yao Yang, Qianwen Zhang, Sha Luoa, Mengqi Ye, Yajiao Zhou, Ying An, Wen Huang, Tengxiao Xuan, Yuexiao Pan, Xuan Xuan, Huacheng He and Jiang Wub (Wenzhou, China - Chemical Engineering Journal).
Nontoxic pH-sensitive silver nanocomposite hydrogels for potential wound healing applications - Tandofonline.com
Abstract by S. Sudarsan, M. S. Selvi, G. Chitra, M. Sakthivel, D. S. Franklin and S. Guhanathan (India - Polymer-Plastics Technology and Materials).
Evaluation of Negative-Pressure Wound Therapy for Surgical Site Infections After Ileostomy Closure in Colorectal Cancer Patients: A Prospective Multicenter Study - Nih.gov
Abstract by Koichi Okuya, Ichiro Takemasa, Tetsuhiro Tsuruma, Ai Noda, Kenichi Sasaki, Tomomi Ueki, Mitsuhiro Mukaiya, Keita Saito, Kenji Okita, Toshihiko Nishidate, Emi Akizuki, Atsushi Hamabe and Masayuki Ishii (Japan - Surg. Today).
A Topical Naltrexone Formulation For Surgical Wound Healing: A Case Report - Wiley.com
Abstract by Jack Dunn, Yi Liu, Fabiana Banov, Sebastian Denison and Daniel Banov (Journal of Cosmetic Dermatology).
pdf (952 kB)!
Comprehensive Review of Hybrid Collagen and Silk Fibroin for Cutaneous Wound Healing - Mdpi.com
Article by Ruth Naomi, Juthamas Ratanavaraporn and Mh Busra Fauzi (Malaysia, Thailand - Materials).
Discovery of Channa striata extracts as regenerative medicine in promoting wound healing and scarless skin regeneration - Eurekaselect.com
Abstract by Soon Hong Kwan and Mohd Nazri Ismail (The Natural Products Journal).
GM-CSF Calibrates Macrophage Defense and Wound Healing Programs During Intestinal Infection and Inflammation - Nih.gov
Abstract by Tomas Castro-Dopico, Aaron Fleming, Thomas W Dennison, John R Ferdinand, Katherine Harcourt, Benjamin J Stewart, Zaeem Cader, Zewen K Tuong, Chenzhi Jing, Laurence S C Lok, Rebeccah J Mathews, Anaïs Portet, Arthur Kaser, Simon Clare and Menna R Clatworthy (UK - Cell Rep.).
Fabrication and Characterization of Ultrathin Spin-Coated poly(L-lactic Acid) Films Suitable for Cell Attachment and Curcumin Loading - Nih.gov
Abstract by Viktoryia Kulikouskaya, Ihnat Chyshankou, Sergei Pinchuk, Irina Vasilevich, Igor Volotovski and Vladimir Agabekov (Minsk, Belarus - Biomed Mater.).
Chitosan/polypropylene Glycol Hydrogel Composite Film Designed With TiO 2 Nanoparticles: A Promising Scaffold of Biomedical Applications - Nih.gov
Abstract by Ahmet Ulu, Emre Birhanlı, Süleyman Köytepe and Burhan Ateş (Malatya, Turkey - Int J Biol Macromol.).
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Insights into Host–Pathogen Interactions in Biofilm-Infected Wounds Reveal Possibilities for New Treatment Strategies - Mdpi.com
Article by Hannah Trøstrup, Anne Sofie Boe Laulund and Claus Moser (Denmark - Antibiotics).
Mathematical Modelling Can Advance Wound Healing Research - Nih.gov
Abstract by Shakti Narayana Menon and Jennifer A Flegg (India, Australia - Adv Wound Care (New Rochelle)).
Polypeptide-Based Self-Healing Hydrogels: Design and Biomedical Applications - Nih.gov
Abstract by Lili Cai, Sa Liu, Jianwei Guo and Yong-Guang Jia (Guangzhou, China - Acta Biomater.).
MicroRNA-21-3p Accelerates Diabetic Wound Healing in Mice by Downregulating SPRY1 - Nih.gov
Abstract by Yaohong Wu, Kun Zhang, Rong Liu, Hexing Zhang, Dong Chen, Shuangqi Yu, Wei Chen, Song Wan, Yi Zhang, Zhiwei Jia, Rongchun Chen and Fan Ding (China - Aging (Albany NY)).
Wound Healing Pathophysiology and Infection - Woundsource.com
With multiple risk factors impeding wound healing and wounds often diagnosed with mixed etiology, wound healing can be complicated. Understanding the pathophysiology of wound healing can help clinicians to better comprehend the needs of a wound to help it progress through the stages
of wound healing.
Topical Timolol for Recalcitrant Hand Eczema - Dermatologyadvisor.com
Article by Emily Pond. The efficacy of topical timolol for the treatment of recalcitrant fissures and erosions in patients with chronic hand eczema was supported in a short communication published in the Journal of the
American Academy of Dermatology.
BIBA Briefings: Critical limb-threatening ischaemia interventions buck trend for emergency only procedures - Iwoundnews.com
A BIBA MedTech Insights survey (conducted May 2020) indicates a trend towards centres only performing emergency percutaneous peripheral procedures during the COVID-19 pandemic. However, this trend is not seen with stenting/angioplasty for critical limb-threatening ischaemia. With critical limb ischaemia, the trend is for at least some elective
procedures to still be performed.
Fat cells help wounds heal - Sciencemag.org
Abstract by Annalisa M. VanHook (USA - Science Signaling).
Toward improved wound healing: Chemical synthesis of a trefoil factor peptide - Phys.org
The fascinating family of trefoil factor peptides brings hope to both research and industry to improve the treatment of chronic disorders such as Crohn's disease. For the first time, a team led by ERC awardee Markus Muttenthaler from the Faculty of Chemistry of the University of Vienna succeeded in the synthesis and folding of the peptide TFF1, a key player in
mucosal protection and repair.
Pre-Clinical Assessment of Single-Use Negative Pressure Wound Therapy During In Vivo Porcine Wound Healing - Nih.gov
Abstract by Varuni R Brownhill, Elizabeth Huddleston, Andrea Bell, Jeffrey Hart, Iain Webster, Matthew Hardman and Holly Nicola Wilkinson (UK - Adv Wound Care (New Rochelle)).
Varicose veins in primary care - Bmj.com
Abstract by Eleanor Atkins, Nadeem A Mughal, Fiona Place and Patrick A Coughlin (BMJ).
Wound closure and coverage techniques - Musculoskeletalkey.com
Article by Robert D Teasdall and James Long.
Knock-out of MicroRNA 145 Impairs Cardiac Fibroblast Function and Wound Healing Post-Myocardial Infarction - Nih.gov
Abstract by Hui-Fang Song, Sheng He, Shu-Hong Li, Jun Wu, Wenjuan Yin, Zhengbo Shao, Guo-Qing Du, Jie Wu, Jiao Li, Richard D Weisel, Subodh Verma, Jun Xie and Ren-Ke Li (China, Canada - J Cell Mol Med.).
Clinical Experiences With Closed Incisional Negative Pressure Wound Treatment on Various Anatomic Locations - Nih.gov
Abstract by Burak Ozkan, Nilgun Markal Ertas, Ulas Bali and Cagri A Uysal (Turkey - Cureus).
Impact of topical nifedipine on wound healing in animal model - Scielo.br
Abstract by Augusto Cézar Lacerda Brasileiro, Dinaldo Cavalcanti de Oliveira, Pollianne Barbosa da Silva and João Kairo Soares de Lima Rocha (Brasil - Jornal Vascular Brasileiro).
pdf (724 kB)!
An overview of the therapeutic potential of regenerative medicine in cutaneous wound healing - Core.ac.uk
Article by Calver Pang, Amel Ibrahim, Neil W Bulstrode and Patrizia Ferretti (USA, UK).
Examination of the Therapeutic Potential of Mouse Oral Mucosa Stem Cells in a Wound-Healing Diabetic Mice Model - Mdpi.com
Article by Shiri Kuperman, Ram Efraty, Ina Arie, Arkadi Rahmanov, Marina Rahmanov Gavrielov, Matityahau Noff, Ron Fishel and Sandu Pitaru (Israel - Int. J. Environ. Res. Public Health).
pdf (1 mB)!
Mechanical Properties of Alginate Based Biopolymers as Wound Dressing Material - Iop.org
Article by Ane Nurjanah, Muhammad Bachri Amran and Rusnadi (Bandung, Indonesia).
Development of NSAID-loaded Nano-Composite Scaffolds for Skin Tissue Engineering Applications - Nih.gov
Abstract by Mubashra Zehra, Azra Mehmood, Muhammad Yar, Lubna Shahzadi and Sheikh Riazuddin (Lahore, Pakistan - J Biomed Mater Res B Appl Biomater.).
Peptide chitosan/dextran core/shell vascularized 3D constructs for wound healing - Pubs.acs.org
Abstract by Paul R. Turner, Eoin Murray, C. John McAdam, Michelle A. McConnell and Jaydee Dones Cabral (ACS Appl. Mater. Interfaces).
Structural features and antimicrobial activity of hydrogels obtained by the sol–gel method from silicon, zinc, and boron glycerolates - Springer.com
Abstract by Tat’yana G. Khonina, Nikolay V. Kungurov, Natal’ya V. Zilberberg, Natal’ya P. Evstigneeva, Muza М. Kokhan, Anton I. Polishchuk, Elena V. Shadrina, Elena Yu. Nikitina, Vasily V. Permikin and Oleg N. Chupakhin (Ekaterinburg, Russia - Journal of Sol-Gel Science and Technology).
Development of Curcumin-Loaded chitosan/pluronic Membranes for Wound Healing Applications - Nih.gov
Abstract by Adalberto Enumo Jr, Débora Fretes Argenta, Giovana Carolina Bazzo, Thiago Caon, Hellen Karine Stulzer and Alexandre Luis Parize (Florianópolis, Brazil - Int J Biol Macromol.).
Synthesis of Chemically Cross-Linked Hydrogel Films Based on Basil Seed (Ocimum Basilicum L.) Mucilage for Wound Dressing Drug Delivery Applications - Nih.gov
Abstract by Masoomeh Sadat Hosseini and Mohammad Reza Nabid (Tehran, Iran - Int J Biol Macromol.).
A Protocol of Systematic Review and Meta-Analysis of Continuous Vacuum Sealing Drainage for Diabetic Foot Ulcer - Nih.gov
Abstract by Xiao-Gang Bai, Jing Wang, Xia Li, Wei Li and Jie Xu (Yan'an, China - Medicine (Baltimore)).
Early Enteral Nutrition in Geriatric Burn Patients: Is There a Benefit? - Physiciansweekly.com
Nutrition is a critical component of acute burn care and wound healing. There is no consensus over the appropriate timing of initiating enteral nutrition in geriatric burn patients. This study aimed to assess the impact of early enteral nutrition on outcomes in this patient population.
Asymmetric Membranes: A Potential Scaffold for Wound Healing Applications - X-mol.com
Abstract by Seyyed Mojtaba Mousavi; Maryam Zarei; Seyyed Alireza Hashemi; Seeram Ramakrishna; Wei-Hung Chiang; Chin Wei Lai; Ahmad Gholami; Navid Omidifar and Mansoureh Shokripour (Symmetry).
Negative Pressure Wound Therapy in the Treatment of Surgical Site Infection in Cardiac Surgery - Nih.gov
Abstract by Mayra de Castro Oliveira, Alessandra Yuri Takehana de Andrade, Ruth Natalia Teresa Turrini and Vanessa de Brito Poveda (São Paulo, Brazil - Rev Bras Enferm.).
Management of a Difficult-to-Treat Diabetic Foot Wound Complicated by Osteomyelitis: A Case Study - Nih.gov
Abstract by Maram Alkhatieb, Hatan Mortada and Hattan Aljaaly (Jeddah, Saudi Arabia - Case Rep Surg.).
Papain Immobilized on Alginate Membrane for Wound Dressing Application - Nih.gov
Abstract by Raimundo Nonato Fernandes Moreira Filho, Niédja Fittipaldi Vasconcelos, Fabia Karine Andrade, Morsyleide de Freitas Rosa and Rodrigo Silveira Vieira (Fortaleza, Brazil - Colloids Surf B Biointerfaces.).
The Impact of Fibrin Sealant Volume on Skin Graft Contraction in a Full-Thickness Skin Graft Model - Nih.gov
Abstract by Ara Kim, Sanghun Lee, Hojune Lee, Ha Seong Lim and So Young Lim (Republic of Korea - J Craniofac Surg.).
Fucoidan-loaded hydrogels facilitates wound healing using photodynamic therapy by in vitro and in vivo evaluation - Sciencedirect.com
Abstract by Karuppusamy Shanmugapriya, Hyejin Kim and Hyun Wook Kang (Busan, South Korea - Carbohydrate Polymers).
PLGF-1 contained in normal wound myofibroblast-derived microvesicles stimulated collagen production by dermal fibroblasts - Springer.com
Abstract by Syrine Arif, Sébastien Larochelle and Véronique J. Moulin (Laval, Canada - Journal of Cell Communication and Signaling).
A Revolution in Healing - Tufts.edu
The science of wound healing goes back to earliest records of civilization. Clay tablets dating back to 2200 BC describe the “three healing gestures”—washing, making the plasters, and bandaging.
Today, the basics of bandaging remain largely unchanged. Skin wounds—cuts, scrapes, punctures and burns—are protected with gauze, held in place by either a cloth wrap or adhesive tape, with the same pragmatic purpose of staunching bleeding and preventing infection.
The Benefits of Moist Wound Healing - Woundsource.com
Moist wound healing is the practice of keeping a wound in an optimally moist environment in order to promote faster healing. Research has shown that moist wound healing is three to five times quicker than the healing of wounds that are allowed to dry out. British researcher George D. Winter described the benefits of moist wound healing in the 1960s.
Closed Incision Negative Pressure Therapy Achieves Better Outcome Than Standard Wound Care: Clinical Outcome and Cost-Effectiveness Analysis in Open Ventral Hernia Repair With Synthetic Mesh Positioning - Nih.gov
Abstract by Leo Licari, Sofia Campanella, Claudia Carolla, Simona Viola and Guseppe Salamone (Palermo, Italy - Cureus).
Negative Pressure Wound Therapy Versus Conventional Dressing for Open Fractures in Lower Extremity Trauma - Nih.gov
Abstract by Muhammad Tahir, Ejaz A Chaudhry, Faridullah K Zimri, Nadeem Ahmed, Saeed A Shaikh, Shoaib Khan, Usama K Choudry, Amer Aziz and Allah R Jamali (Pakistan, United Kingdom - Bone Joint J.).
An Application of a Negative-Pressure Wound Dressing for Partial- Or Full-Thickness Burn Wounds - Nih.gov
Abstract by Yulong Cheng, Zengding Zhou, Huan Hu, Wenbo Li, Yi Liu, Zihuan Xia, Chenliang Deng, Guangyu Mao, Lei Yi, Xiangdong Liu, Songlin Yang, Jianghong Zheng and Feng Guo (Shanghai, China - Int J Low Extrem Wounds.).
Clinical Application of Self-Made Drainage Tubes in Different Layers of Soft Tissue for Negative-Pressure Wound Therapy in 33 Patients - Nih.gov
Abstract by Y H Zhao, C D Xia, G Y Shao, Y Y Feng, W Xiong, Y M Shen, L L Xu, W Q Huang, H T Deng and D L Yuan (Jiangyin, China - Zhonghua Shao Shang Za Zhi.).
Paracrine SPARC signaling dysregulates alveolar epithelial barrier integrity and function in lung fibrosis - Nature.com
Article by Franco Conforti, Robert Ridley, Christopher Brereton, Aiman Alzetani, Benjamin Johnson, Ben G. Marshall, Sophie V. Fletcher, Christian H. Ottensmeier, Luca Richeldi, Paul Skipp, Yihua Wang, Mark G. Jones and Donna E. Davies (UK, Italy - Cell Death Discovery).
Oxygen-Ozone (O2-O3) Therapy in Peripheral Arterial Disease (PAD): A Review Study - Dovepress.com
Downloadable article by Hanna Juchniewicz and Anna Lubkowska (Szczecin, Poland - Therapeutics and Clinical Risk Management).
Hypothesis Validation of Rosiglitazone a Potential Inhibitor Against Glycogen Synthase kinase-3β, for the Management of Multifaceted Pathophysiology of the Diabetic Wound: An Insilico Study - Nih.gov
Abstract by Tajuddin Mohammed, Bharat Kumar Reddy Sanapalli, Sayyada Saleha Momina, Rakesh Kumar Jat and Nagakanyaka Devi Paladugu (India - Med Hypotheses.).
Rare Case of Adhesive Large Bowel Obstruction in Acute Burn Patient: Management of Open Abdomen With ABTHERA ADVANCE™ Open Abdomen Dressing - Nih.gov
Abstract by Yao C Huang, Elizabeth Vujcich and Jason Brown (Brisbane, Australia - J Surg Case Rep.).
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