Hungarian Wound Care Society

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News from the field of wound care and wound healing - June, 2020

ECET 2021 joins forces with EWMA 2021 - Ewma.org
The 2021 conference of the European Council of Enterostomal Therapist, ECET, will be held jointly with the annual EWMA Conference, EWMA-Journées Cicatristations 2021.


Diabetic foot: the cancer of diabetes - Healthawareness.co.uk
Article by Alberto Piaggesi. It has been estimated that a limb is lost every 30 seconds in the world because of diabetic foot. And the associated mortality is higher than that of many forms of cancer. More must be done to raise awareness of the chronic complications of diabetes.


The Challenge of Managing Wounds and Pressure Injuries During COVID-19 - Todayswoundclinic.com
As health care providers scramble to treat COVID-19 patients and try to prevent the spread of the novel coronavirus, concerns are arising such as the potential for more pressure injuries. Several expert panelists discuss their experiences and how they are using innovations like telemedicine to adapt.


Idiopathic Necrotizing Fasciitis Following Fracture Fixation: A Case Report - Nih.gov
Abstract by Muhammad Umar Joomun, Zhiya Li, Deting Xue, Huawei Shao and Zhijun Pan (China - Medicine (Baltimore)).


Prophylactic Negative Pressure Wound Therapy for Closed Laparotomy Wounds: A Systematic Review and Meta-Analysis of Randomised Controlled Trials - Nih.gov
Abstract by Patrick Anthony Boland, Michael E Kelly, Noel E Donlon, Jarlath C Bolger, Brian J Mehigan, Paul H McCormick and John O Larkin (Dublin, Ireland - Ir J Med Sci.).


Soft Tissue Coverage for Severe Infections - Nih.gov
Abstract by Vanessa Prokuski and Adam Strohl (USA - Hand Clin.).


Beyond the Bandage: A Look at Adjustable Compression Wraps - Woundcarelearningnetwork.com
Article by Erin Fazzari. Complete decongestive therapy (CDT) is the standard of care for the treatment of lymphedema. This includes skin and wound care, manual lymphatic drainage, remedial exercises, and compression therapy. In the active decongestive phase, compression therapy typically involves the use of a multi-layered, short stretch compression bandage with open celled-foam.


When the Traditional Approach is Not an Option - Then What? - Woundcarelearningnetwork.com
Article by Suzie Ehmann. Compression is an essential component for the acute treatment and long-term management of chronic edema conditions. However, clinically, it is not unusual that patients present with comorbidities, environmental challenges, and /or behaviors that preclude the consistent use of standard of care compression therapy.


Pain Relief from Lymphedema Therapy with Intermittent Pneumatic Compression in Patients with COPD? - Woundcarelearningnetwork.com
Poster by Amanda L Killeen, Kara M Brock, Bradley James and Jodi L Walters.


Researchers use electric fields to herd cells like flocks of sheep - Princeton.edu
Article by Molly Sharlach. Princeton researchers have created a device that can herd groups of cells like sheep, precisely directing the cells’ movements by manipulating electric fields to mimic those found in the body during healing. The technique opens new possibilities for tissue engineering, including approaches to promote wound healing, repair blood vessels or sculpt tissues.


Pigment Epithelium-Derived Factor Attenuates Angiogenesis and Collagen Deposition in Hypertrophic Scars - Nih.gov
Abstract by Da Ma, Lin Chen, Junhe Shi, Yan Zhao, Shruti Vasani, Kevin Chen, Bruna Romana-Souza, Jack Henkin and Luisa A DiPietro (China, USA, Brazil - Wound Repair Regen.).


Epidemiological Characteristics and Clinical Analyses of Chronic Cutaneous Wounds of Inpatients in China: Prevention and Control - Nih.gov
Abstract by Biao Cheng, Yufeng Jiang, Xiaobing Fu, Daifeng Hao, Hongwei Liu, Yi Liu, Zhifeng Huang, Qian Tan, Lingfeng Wang, Dahai Hu, Yanqing Yang, Chunmao Han, Zhifeng Cheng, Xingwu Ran and Ying Li (China - Wound Repair Regen.).


Chitosan Dressings Containing Inorganic Additives and Levofloxacin as Potential Wound Care Products With Enhanced Hemostatic Properties - Nih.gov
Abstract by Ioanna Koumentakou, Zoi Terzopoulou, Anna Michopoulou, Ilias Kalafatakis, Konstantinos Theodorakis, Dimitrios Tzetzis and Dimitrios Bikiaris (Greece - Int J Biol Macromol.).


Teicoplanin-loaded chitosan-PEO Nanofibers for Local Antibiotic Delivery and Wound Healing - Nih.gov
Abstract by Nafise Amiri, Saeed Ajami, Azadeh Shahroodi, Nafise Jannatabadi, Shahrzad Amiri Darban, Bibi Sedigheh Fazly Bazzaz, Elham Pishavar, Fatemeh Kalalinia and Jebrail Movaffagh (Mashhad, Iran - Int J Biol Macromol.).


Tannic acid-reinforced methacrylated chitosan/methacrylated silk fibroin hydrogels with multifunctionality for accelerating wound healing - Sciencedirect.com
Abstract by XiHe, Xuezhe Liu, Jin Yang, Haibo Du, Ningwen Chai, Zhou Sha, Mengru Geng, Xiaojun Zhou and Chuanglong He (Shanghai, China - Carbohydrate Polymers).


What Is Antifungal Cream? - Woundsource.com
Antifungal cream is a broad term used to describe a range of products containing antifungal agents that are topically applied to the skin to control and manage fungal infections. These products may be formulated with a moisture barrier to protect and condition the skin. Antifungal creams are used both as a palliative treatment for existing fungal infections and as a prophylactic measure in cases where there is a risk of fungal infection.


Treatment of Deep Full-thickness Wounds Containing Exposed Muscle, Tendon, and/or Bone Using a Bioactive Human Skin Allograft: A Large Cohort Case Series - Woundresearch.com
Article by Michael S. Flood, Blake Weeks, Kenneth O. Anaeme, Heather Aguirre, Kimberlee B. Hobizal, Sandi E. Jiongco, Robert J. Klein, Andrew Lemoi, Rafael Rafols and Adam S. Landsman (USA - Wounds).


Early-stage Management of Complex Lower Extremity Wounds Using Negative Pressure Wound Therapy With Instillation and a Reticulated Open Cell Foam With Through Holes - Woundresearch.com
Article by Windy Cole (Independence, USA - Wounds).


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Nanoparticle-Based Therapeutic Approach for Diabetic Wound Healing - Mdpi.com
Article by Hariharan Ezhilarasu, Dinesh Vishalli, S. Thameem Dheen, Boon-Huat Bay and Dinesh Kumar Srinivasan (Singapore, India - Nanomaterials).


Wound healing after excision of subcutaneous tumors treated with near‐infrared photoimmunotherapy - Wiley.com
Article by Adrian Rosenberg, Fuyuki Inagaki, Takuya Kato, Ryuhei Okada, Hiroaki Wakiyama, Aki Furusawa, Peter L. Choyke and Hisataka Kobayashi (Bethesda, USA - Cancer Medicine).


The Experience of Using the Drug Reamberin and NPWT-therapy in Preparing Wounds for Autodermoplasty - Nih.gov
Abstract by M V Varganov, A A Miklichev and K D Bogdanov (Izhevsk, Russia - Khirurgiia (Mosk).).


Limb Salvage Procedure in Immunocompromised Patients With Therapy-Resistant Leg ulcers-The Value of Ultra-Radical Debridement and Instillation Negative-Pressure Wound Therapy - Nih.gov
Abstract by Alexander Geierlehner, Raymund E Horch, Wibke Müller-Seubert, Andreas Arkudas and Ingo Ludolph (Erlangen, Germany - Int Wound J.).


Are ‘smart’ bandages the future of wound care? - Medicaldevice-network.com
Effective treatment options for chronic wounds are limited, but the consequences of poor management can be devasting and even lead to amputation. Natalie Healey speaks to Dr Ali Tamayol, from the University of Connecticut who has developed a wirelessly controlled bandage that precisely delivers a combination therapy deep into the wound to encourage healing.


The Effect of Form of Carboxymethyl-Chitosan Dressings on Biological Properties in Wound Healing - Nih.gov
Abstract by Dong Wang, Nihui Zhang, Guolong Meng, Jing He and Fang Wu (Chengdu, China - Colloids Surf B Biointerfaces.).


Multi-layer Dressing Made of Laminated Electrospun Nanowebs and Cellulose-Based Adhesive for Comprehensive Wound Care - Nih.gov
Abstract by Ahmed A Nada, Eman A Ali, Ahmed A F Soliman, Jialong Shen, Nabil Y Abou-Zeid and Samuel M Hudson (Egypt, USA - Int J Biol Macromol.).


Dual Spinneret Electrospun nanofibrous/gel Structure of chitosan-gelatin/chitosan-hyaluronic Acid as a Wound Dressing: In-vitro and In-Vivo Studies - Nih.gov
Abstract by Abbas Zakeri Bazmandeh, Esmaeil Mirzaei, Milad Fadaie, Sadegh Shirian and Younes Ghasemi (Iran - Int J Biol Macromol.).


Chitosan dressings containing inorganic additives and levofloxacin as potential wound care products with enhanced hemostatic properties - Sciencedirect.com
Abstract by Ioanna Koumentakou, Zoi Terzopoulou, Anna Michopoulou, Ilias Kalafatakis, Konstantinos Theodorakis, Dimitrios Tzetzis and Dimitrios Bikiaris (Greece - International Journal of Biological Macromolecules).


Nanospheres Loaded with Curcumin Improve the Bioactivity of Umbilical Cord Blood-Mesenchymal Stem Cells via c-Src Activation During the Skin Wound Healing Process - Nih.gov
Article by Do-Wan Kim, Chang-Hyung Choi, Jong Pil Park and Sei-Jung Lee (Korea - Cells).


Effective Enzymatic Debridement of Burn Wounds Depends on the Denaturation Status of Collagen - Nih.gov
Abstract by Kelly A A Kwa, Ludo van Haasterecht, Anouk Elgersma, Roelf S Breederveld, Marie Louise Groot, Paul P M van Zuijlen, Bouke K H L Boekema (The Netherlands - Wound Repair Regen.).


The Impact of Negative-Pressure Wound Therapy With Instillation on Wounds Requiring Operative Debridement: Pilot Randomised, Controlled Trial - Nih.gov
Abstract by Paul J Kim, Lawrence A Lavery, Robert D Galiano, Christopher J Salgado, Dennis P Orgill, Stephen J Kovach, Brent H Bernstein and Christopher E Attinger (USA - Int Wound J.).


Effect of Decellularized Adipose Tissue Combined With Vacuum Sealing Drainage on Wound Inflammation in Pigs - Nih.gov
Abstract by Yiming Wang, Wenxin Wei and Yan Han (Beijing, China - Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi.).


Plasma Endothelial Cells-Derived Extracellular Vesicles Promote Wound Healing in Diabetes Through YAP and the PI3K/Akt/mTOR Pathway - Nih.gov
Abstract by Feng Wei, Aixue Wang, Qing Wang, Wenrui Han, Rong Rong, Lijuan Wang, Sijia Liu, Yimeng Zhang, Chao Dong and Yanling Li (Shijiazhuang, China - Aging (Albany NY)).


Genetics May Play Key Role in Wound Healing - Genengnews.com
Researchers say they have completed a first-of-its-kind study that determines that genetics may play a role in how wounds heal.


Single-layered Versus Multiple-Layered Wound Closure for Flank Incision: Results of a Prospective, Randomized, Double-Blinded Multicenter Study - Nih.gov
Abstract by Maximilian C Kriegmair, Nina Younsi, Kiriaki Hiller, Conrad Leitsmann, Karl F Kowalewski, Fabian Siegel, Martin Rothamel, Manuel Ritter, Christian Bolenz, Martin Kriegmair, Lutz Trojan and Maurice S Michel (Germany - BJU Int.).


A Comparison of Subconjunctival Wound Healing Between Different Methods of Dissecting Subconjunctival Tissues - Nih.gov
Abstract by Ruowen Gong, Chengguo Zuo, Keling Wu, Simin Zhang, Xi Qin, Yangyang Li, Xinbo Gao, Danping Huang and Mingkai Lin (Ophthalmic Res.).


Is honey effective for healing? - Telanganatoday.com
Honey has been shown to have an antibacterial effect on bacteria commonly present in wounds.


Changing the patterns of hospitalized diabetic foot ulcer (DFU) over a 5-year period in a multi-disciplinary setting in Thailand - Biomedcentral.com
Article by Yotsapon Thewjitcharoen, Jeeraphan Sripatpong, Sirinate Krittiyawong, Sriurai Porramatikul, Taweesak Srikummoon, Somkiet Mahaudomporn, Siriwan Butadej, Soontaree Nakasatien and Thep Himathongkam (Bangkok, Thailand - BMC Endocrine Disorders).


Corneal wound healing - Meta.org
Abstract by Steven E Wilson.


Time laps of wound healing - Meta.org
A 3:04 video.


A Supersaturated Oxygen Emulsion for Wound Care and Skin Rejuvenation - Nih.gov
Abstract by Michael H Gold and Mark S Nestor (J Drugs Dermatol.).


Preparation of Smooth and Macroporous Hydrogel via Hand-Held Blender for Wound Healing Applications: in-vitro and in-vivo Evaluations - Nih.gov
Abstract by Weiyu Zhang, Xiaoxuan Ma, Yang Li and Daidi Fan (China - Biomed Mater.).


Development of Satureja Cuneifolia-Loaded Sodium alginate/polyethylene Glycol Scaffolds Produced by 3D-printing Technology as a Diabetic Wound Dressing Material - Nih.gov
Abstract by Elif Ilhan, Sumeyye Cesur, Ece Guler, Fadime Topal, Deniz Albayrak, Mehmet Mucahit Guncu, Muhammet Emin Cam, Turgut Taskin, Hilal Turkoglu Sasmazel, Burak Aksu, Faik Nuzhet Oktar and Oguzhan Gunduz (Turkey, United Kingdom - Int J Biol Macromol.).


Negative pressure wound therapy vs conventional wound treatment in subcutaneous abdominal wound healing Impairment: The SAWHI randomized clinical trial - Mdlinx.com
Abstract by Seide D, Diedrich S, Herrle F, et al (JAMA).


Alginate Versus NPWT in the Preparation of Surgical Excisions for an STSG: ATEC Trial - Nih.gov
Article by Dominique Casanova, Pierre Guerreschi, Raphael Sinna, Nicolas Bertheuil, Cécile Philandrianos, Bérengère Chignon-Sicard, Franck Duteille, Michael Atlan, Pascal Rousseau, Gilles Chatellier, Fabien Boucher, Nathalie Pham Dang, Adeline Cambon-Binder, Audrey Michot, Isabelle Pluvy, Frédéric Seigle-Murandi, Weiguo Hu and Marc Revol (France - Plast Reconstr Surg Glob Open.).


Researchers develop microscopy technique for noninvasive evaluation of wound healing - Eurekalert.org
Researchers at the GSK Center for Optical Molecular Imaging have developed a new microscope that looks at the different parameters that change during wound healing. They hope to use this technique to understand how skin disorders, such as foot ulcers in diabetic patients and psoriasis, can be treated.


Wound Management With Active Leptospermum Honey - Woundcarelearningnetwork.com
Infographic by Ferne T. Elsass.


Closed Incision Negative Pressure Wound Therapy After Resection of Large, Radiated, Soft Tissue Sarcomas - Nih.gov
Abstract by Timothy J Irwin and Dennis Orgill (Boston, USA - Cureus).


Skin Repair and Healing: Research into Collagen & Polysaccharide Bioinks - 3dprint.com
Researchers from Australia and China continue the recent trend for exploring the uses of 3D printing and bioprinting for tissue regeneration and wound healing, reviewing the latest research and techniques in ‘Advances in the Research of Bioinks Based on Natural Collagen, Polysaccharide and Their Derivatives for Skin 3D Bioprinting.


The Effects and Use of Negative Pressure Wound Therapy - A Set of Case Reports - Nih.gov
Abstract by L Brzulová, J Škach, K Kocmanová, A Škaryd and P Hromádka (Rozhl Chir.).


The Effects and Use of Negative Pressure Wound Therapy - A Set of Case Reports - Mdlinx.com
Abstract by Highcock AJ, As-Sultany M, Finley R, et al (Journal of Arthroplasty).


Evaluation of the Efficacy of Ultrapulsed CO 2 Laser in Chronic Wounds - Nih.gov
Abstract by Bo Jiang, Rui Tang, Danyu Zheng, Yuting Yang, Ying Li, Ruxi Yang, Ligang Liu and Hong Yan (Sichuan, China - Lasers Surg Med.).


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Demonstration of re-epithelialization in a bioprinted human skin equivalent wound model - Biorxiv.org
Article by Carlos Poblete Jara, Carolina Motter Catarino, Yuguo Lei, Lício Augusto Velloso, Pankaj Karande, William H. Velander and Eliana Pereira de Araujo (Brazil, USA).


Negative pressure wound therapy for surgical wounds healing by primary closure - Cochranelibrary.com
Abstract by Gill Norman, En Lin Goh, Jo C Dumville, Chunhu Shi, Zhenmi Liu, Laura Chiverton, Monica Stankiewicz and Adam Reid (Australia, UK).


Role of Xanthine Oxidoreductase in Diabetic Wound Healing - Pitt.edu
Presenter: Kathy Gonzalez. Impaired diabetic wound healing is attributed to increased reactive oxygen species (ROS) and decreased nitric oxide (NO) production...


Role of Xanthine Oxidoreductase in Diabetic Wound Healing - Researchsquare.com
Abstract by Ling Guo, Ya Zhang, Juan Du, Dan Feng Yuan, Shu Zhang, Hua Cai Zhang, Jun Wei Mi, Ya Lei Ning, Min Jia Chen, Da Lin Wen, Jian Hui Sun, Di Liu, Ling Zeng, An Qiang Zhang, Jian Xin Jiang and Hong Huang.


Graphene stimulates wound healing - Medicalxpress.com
Chronic or hard-to-heal wounds, those that do not heal after six weeks, place a significant economic burden on health systems around the world, costing around $30 billion annually. They lead to half-a-million amputations per year globally. In the United States alone, more than 6.5 million people suffer from such wounds. Faced with this problem and considering that proper assessment of these wounds is not within the reach of caregivers with the relevant expertise, Graphene Flagship scientists in France have developed a new graphene patch that allows them to be monitored remotely.


Phomopsidione-loaded Chitosan Polyethylene Glycol (PEG) Nanocomposite Dressing for Pressure Ulcers - Nih.gov
Abstract by Ihsan Bin Idris Chin, Tong Woei Yenn, Leong Chean Ring, Yusriah Lazim, Wen-Nee Tan, Syarifah Ab Rashid, Cheng See Yuan, Zaida Rahayu Yet, Siti Zubaidah Abdullah and Md Abu Taher (Malaysia - J Pharm Sci.).


Photodynamic therapy in wound healing in vivo: a systematic review - Sciencedirect.com
Abstract by Jully Oyama, Áquila Carolina Fernandes Herculano Ramos-Milaré, Daniele Stéfanie Sara Lopes Lera-Nonose, Vanessa Nesi-Reis, Izabel Galhardo Demarchi, Sandra Mara Alessi Aristides, Jorge Juarez Vieira Teixeira, Thaís Gomes Verzignassi Silveirac and Maria Valdrinez Campana Lonardonic (Brazil - Photodiagnosis and Photodynamic Therapy).


Bacterial Controller Aided Wound Healing: A Case Study in Dynamical Population Controller Design - Biorvix.org
Downloadable article by Leopold N. Green Jr., Chelsea Y. Hu, Xinying Ren and Richard M Murray (Pasadena, USA).


New Bandages May Boost Healing Of Diabetic And Chronic Wounds - Medicaldialogues.in
University of Sheffield engineers have developed new dressings that could boost the healing process in patients with burns injuries or chronic woundsNew dressings contain an agent that helps to form new blood vessels - a critical part of the healing process.


The Wound Healing Process - Woundsource.com
Promoting the wound healing process is a primary responsibility for most health care practitioners. It can take 1-3 days for a closed wound to actually establish a seal. Infections usually occur in 3-6 days but may not appear for up to 30 days, according to the CDC guidelines for preventing surgical infections.


Mesenchymal Stromal Cells Pretreated With Pro-Inflammatory Cytokines Promote Skin Wound Healing Through VEGFC-mediated Angiogenesis - Nih.gov
Abstract by Mengting Zhu, Yunpeng Chu, Qianwen Shang, Zhiyuan Zheng, Yanan Li, Lijuan Cao, Yongjing Chen, Jianchang Cao, Oscar K Lee, Ying Wang, Gerry Melino, Guozhong Lv, Changshun Shao and Yufang Shi (China, Italy - Stem Cells Transl Med.).


Application of Stable Continuous External Electric Field Promotes Wound Healing in Pig Wound Models - Nih.gov
Abstract by Yi Liang, Hao Tian, Jie Liu, YanLing Lv, Yuan Wang, JiaPing Zhang and YueSheng Huang (China - Bioelectrochemistry).


Can Skin Cells Improve Outcomes for Patients With Deep Burns? - Woundresearch.com
Article by Laura Bolton (New Brunswick, USA). Early excision and split-thickness skin autografts (STSGs) have become standard care for full-thickness burns, but healing the donor site challenges these patients who are already at metabolic and microbial risks, increasing with the total body surface area (TBSA) burned.


Outcomes and Characteristics of Wound Healing in an Outpatient Physical Therapy Clinic - Woundresearch.com
Article by Kehua Zhou, Leslie Frankish and Michael Ross (USA, Taiwan - Wounds)


Antimicrobial activities of bacterial cellulose – Silver montmorillonite nanocomposites for wound healing - Sciencedirect.com
Abstract by Manuel Horue, Maximiliano L.Cacicedo, Mariela A. Fernandez, Boris Rodenak-Kladniew, Rosa M.Torres Sánchez and Guillermo R.Castroa (La Plata, Argentina).


How COVID-19 Is Changing Wound Care and Why You Should Be Preparing Now for the Next Wave - Sciencedirect.com
Article by Lee C. Rogers. COVID-19 has changed the way wound clinics operate, with wound care becoming untethered from site-specific locations. This author provides guidance for adjusting wound clinic practices to prep for a potential second wave of infection this winter, as well as developing a post-pandemic wound care model that can include providing wound care without walls.


Traditional and Advanced Therapeutic Modalities for Wounds in the Paediatric Population: An Evidence-Based Review - Nih.gov
Abstract by Stephanie A McNamara, Penelope A Hirt, Maximillian A Weigelt, Sonali Nanda, Valeria de Bedout, Robert S Kirsner and Lawrence A Schachner (Miami, USA - J Wound Care.).


Negative Pressure Wound Therapy Affects Circulating Plasma microRNAs in Patients With Diabetic Foot ulceration - Nih.gov
Abstract by Przemysław Kapusta, Pawel S Konieczny, Jerzy Hohendorff, Sebastian Borys, Justyna Totoń-Żurańska, Beata M Kieć-Wilk, Pawel P Wołkow and Maciej T Malecki (Krakow, Poland - Diabetes Res Clin Pract.).


Croton Urucurana Baillon Stem Bark Ointment Accelerates the Closure of Cutaneous Wounds in Knockout IL-10 Mice - Nih.gov
Abstract by Thalia Del Rosario Loyo Casao, Camila Graça Pinheiro, Mariáurea Matias Sarandy, Ana Caroline Zanatta, Wagner Vilegas, Rômulo Dias Novaes, Reggiani Vilela Gonçalves and João Paulo Viana Leite (Brazil - J Ethnopharmacol.).


Reducing Hematomas and Skin Complications - Woundcarelearningnetwork.com
Poster. Hematomas are caused by accumulation of clotted blood resulting from bleeding usually associated with trauma, anticoagulation therapy or surgically induced tissue injury.


Management of Deep Sternal Wound Infection: Complete Sternal Osteomyelitis - Nih.gov
Abstract by Khaled Ebrahim Al-Ebrahim (Jeddah, Saudi Arabia - Heart Surg Forum.).


The Utility of Portable Negative Pressure Wound Therapy in the Management of Prosthetic Dialysis Arteriovenous Graft Infection - Nih.gov
Abstract by Nobuhisa Morimoto, Madoka Tanabe, Atsuhiro Imono, Megumi Otani, Shingo Shioji, Suguru Hirasawa, Shota Aki, Makoto Aoyagi and Hiroyuki Tanaka (Yokosuka, Japan - J Vasc Access.).


Prophylactic Use of Negative Pressure Wound Therapy Reduces Surgical Site Infections in Elective Colorectal Surgery: A Prospective Cohort Study - Nih.gov
Abstract by Pedro Abadía, Juan Ocaña, Diego Ramos, Juan D Pina, Irene Moreno, Juan C García, Gloria Rodríguez, Estela Tobaruela and Javier Die (Madrid, Spain - Surg Infect (Larchmt).).


A Free-Standing Multilayer Film as a Novel Delivery Carrier of Platelet Lysates for Potential Wound-Dressing Applications - Nih.gov
Abstract by Qian Tang, Thou Lim, Xiao-Juan Wei, Qi-Yang Wang, Jian-Chen Xu, Li-Yan Shen, Zhen-Zhong Zhu and Chang-Qing Zhang (China - Biomaterials.).


How to Enhance the Management of Chronic Conditions When You Can’t See Your Patients - Woundsource.com
We know that telemedicine cannot replace an in-person visit to a provider, but during this time of crisis it serves as an advanced approach in wound care.


Negative Pressure Wound Therapy in Pyoderma Gangrenosum Treatment - Nih.gov
Abstract by Dariusz Bazaliński, Anna Karwiec, Marek Kucharzewski and Paweł Więch (Poland - Am J Case Rep.).


Quick Facts – COVID-19 and Wound Care - Woundsource.com
Infographics.


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Nigella sativa and Its Active Compound, Thymoquinone, Accelerate Wound Healing in an In Vivo Animal Model: A Comprehensive Review - Mdpi.com
Article by Nusaibah Sallehuddin, Abid Nordin, Ruszymah Bt Hj Idrus and Mh Busra Fauzi (Kuala Lumpur, Malaysia - International Journal of Environmental Research and Public Health).


Are "Smart" Bandages the Future of Wound Care? - Nridigital.com
Effective treatment options for chronic wounds are limited, but the consequences of poor management can be devastating and even lead to amputation. Natalie Healey speaks to Dr Ali Tamayol, from the University of Connecticut, who has developed a wirelessly controlled bandage that precisely delivers a combination therapy deep into the wound to encourage healing.


Thuja occidentalis mediated AuNPs as wound dressing agents for abdominal wound healing in nursing care after surgery - Springer.com
Abstract by Yan Dong, Xiu-Mei Hu, Yun-Feng Cao, Ya-Chao Wang, Ling-Zi Li, Jian-Yu Lu and Xiu-Xia Li (Shandong, China).


Potential Molecular Mechanisms of Negative Pressure in Promoting Wound Healing - Nih.gov
Abstract by Jiaoyun Dong, Chun Qing, Fei Song, Xiqiao Wang, Shuliang Lu and Ming Tian (Shanghai, China - Int Wound J.).


In Vivo Wound Healing and In Vitro Anti-Inflammatory Activity Evaluation of Phlomis russeliana Extract Gel Formulations - Mdpi.com
Article by Mehmet Evren Okur, Ayşe Esra Karadağ, Neslihan Üstündağ Okur, Yağmur Özhan,Hande Sipahi, Şule Ayla, Benay Daylan, Betül Demirci and Fatih Demirci (Turkey, Cyprus).


Stem cell-loaded microneedles speed up wound healing - Newatlas.com
Article by Michael Irving. Stem cells are powerful tools that could one day unlock new frontiers in regenerative medicine. Now, a new study has shown that a certain type of stem cell can be delivered into injured tissues with dissolvable microneedles, to heal wounds.


Topical ozonated virgin coconut oil improves wound healing and increases HSP90α, VEGF-A, EGF, bFGF and CD34 in diabetic ulcer mouse model of wound healing - F1000research.com
Article by Renni Yuniati, Prasetyowati Subchan, Wibi Riawan, Matthew Brian Khrisna, Maryam Restiwijaya, Niken Safitri Dyan and Muhammad Nur (Java, Indonesia).


Is itching really a sign of wound healing - Youtube.com
Putting a bandage over an open wound helps it heal by preventing dirt and other particles from hurting the wound even more - a 1:36 video.


Determinants of Success After Metatarsal Head Resection for the Treatment of Neuropathic Diabetic Foot Ulcers - Jfas.org
Abstract by Alireza Kalantar Motamedi and Mohammad Ansari Kalantar Motamedi (The Journal of Foot & Ankle Surgery).


Continuous Wound Infiltration With Ropivacaine After Mastectomy: A Randomized Controlled Trial - Nih.gov
Abstract by Marie Beguinot, Emilie Monrigal, Fabrice Kwiatkowski, Angeline Ginzac, Dominique Joly, Guillaume Gayraud, Guillaume Le Bouedec and Pierre Gimbergues (France - J Surg Res.).


Adaptive Expression of Biofilm Regulators and Adhesion Factors of Staphylococcus aureus During Acute Wound Infection Under the Treatment of Negative Pressure Wound Therapy in vivo - Nih.gov
Abstract by Tongtong Li, Guoqi Wang, Peng Yin, Zhirui Li, Lihai Zhang and Peifu Tang (China - Exp Ther Med.).


Effects of Negative Pressure Wound Therapy Associated With Local Insulin Injection on TGF-β1 Expression in Diabetic Foot Wounds - Nih.gov
Abstract by Y L Huang, F Ju, S C Lai, Z C Chen, X Y Chen, L H Zhou and M X Fu (Haikou, China - J Biol Regul Homeost Agents.).


Negative-pressure Wound Therapy Does Not Reduce Superficial SSI in Pancreatectomy and Hepatectomy Procedures - Nih.gov
Abstract by Conor H O'Neill and Robert C G Martin 2nd (Louisville, USA - J Surg Oncol.).


Antioxidant dressing therapy versus standard wound care in chronic wounds (the REOX study): study protocol for a randomized controlled trial - Biomedcentral.com
Article by Inés María Comino-Sanz, María Dolores López-Franco, Begoña Castro and Pedro Luis Pancorbo-Hidalgo (Spain).


Protein Tyrosine Phosphatase 1B Inhibition as a Potential Therapeutic Target for Chronic Wounds in Diabetes - Nih.gov
Abstract by Ana Margarida da Silva Figueiredo, Ermelindo Carreira Leal and Eugénia Maria Lourenço de Carvalho (Coimbra, Portugal - Pharmacol Res.).


Microbiota-sourced purines support wound healing and mucus barrier function - Sciencedirect.com
Downloadable article by J. Scott Lee, Ruth X. Wang, Matthew S. Goldberg, Garrett P. Clifford, Daniel J. Kao and Sean P. Colgan (Aurora, USA).


Digging in With Diabetic Foot Ulcers - Woundcarelearningnetwork.com
Article by Dana R. Windsor. Diabetic foot ulcers (DFUs) are the most common lower extremity complication of diabetic patients, and can lead to devastating consequences if not managed quickly and effectively. It is estimated that DFUs will affect about 15% to 35% of people with diabetes during their lifetime and will contribute to about 20% of hospital admissions among patients with diabetes.


Assessing DFU Perfusion: Comparing the Tried & True to the Novel & New - Todayswoundclinic.com
Article by Windy Cole and Stacey Coe. Is near-infrared spectroscopy a promising noninvastive vascular study to measure tissue perfusion in diabetic foot ulcers? Presenting a case study, these authors assess how an innovative device can provide clinicians a better picture of the potential for wound healing.


Basics of Podiatry for the Non-podiatrist: Part 1 - Woundcarelearningnetwork.com
In this podcast Steve Bergquist, MD, CWSP, talks with Windy Cole, DPM, about the basics of podiatry. Dr. Cole discusses how she treats diabetic foot ulcers, venous leg ulcers, and other ulcer types with non-podiatrists in mind.


Novel Management of Diabetic Foot Ulcers Using Injectable Micronized Dehydrated Amnion Chorion Membrane (dHACM) Allograft Tissue: Two Case Studies - Woundcarelearningnetwork.com
Poster by Zeyad Tareq Al-Azzawi, William Tettelbach and Hussam Itani.


Suction Drains - Nih.gov
Article by BA Ramesh and Jayalakshmi BK. (India).


Improved Perioperative Seroma and Complication Rates Following the Application of a 2-Layer Negative Pressure Wound Therapy System After Inguinal Lymphadenectomy for Metastatic Cutaneous Melanoma - Nih.gov
Abstract by Marc D Moncrieff, Riti A Sharma, Esther Gathura and Martin J Heaton (Norwich, United Kingdom - Ann Surg Oncol.).


Lessons Learned From Implementation and Management of Skin Allograft Banking Programs in Low- And Middle-Income Countries: A Systematic Review - Nih.gov
Abstract by Jeffrey L Roberson, Julie Pham, Jolie Shen, Kelly Stewart, Paa Ekow Hoyte-Williams, Kajal Mehta, Shankar Rai, Jorge Morales Pedraza, Nikki Allorto, Tam N Pham and Barclay T Stewart (USA, Ghana, Nepal, Austria, South Africa - J Burn Care Res.).


New wound-healing research project wins NASA tick of approval - Miragenews.com
A group of Australian scientists has caught the attention of NASA with a novel technology development that could potentially heal wounds in days rather than weeks without using stitches.


ETH researchers deconstruct tissue repair - Eurekalert.org
Anyone who is injured hopes for a speedy recovery. But wounds that heal too quickly can heal badly: if the concentration of certain growth factors becomes too high and the healing process overshoots the mark, then bulging (in technical jargon: hypertrophic) scars form and even the surrounding skin loses some of its elasticity.


Researchers identify secretion mechanisms for a protein necessary for maintaining healthy connective tissues - Medicalexpress.com
Researchers have discovered that a defective form of the protein aortic carboxypeptidase-like protein (ACLP) from patients with Ehlers-Danlos syndrome (EDS) is retained in cells and induces cellular stress. This finding may provide targets for pharmacologic and therapeutic interventions in treating individuals with EDS as well as wound healing disorders and fibrosis.


Combined Timed Surgery and Conservative Management of Primary Necrotizing Fasciitis of the Breast: A Case Report - Nih.gov
Abstract by Concetta Anna Dodaro, Antonio Zaffiro, Anna Maria Iannicelli, Ludovica Giordano, Luigi Sorbino, Francesco Mangiapia, Mariangela Lanzano and Fabrizio Schonauer (Naples, Italy - Am J Case Rep.).


Wound Complications And Reoperations Following Transtibial Amputation Of The Leg - Nih.gov
Abstract by Ahmed Khouqeer, Alexander Uribe-Gomez, Sherene S Sharath, Panos Kougias and Neal R Barshes (Houston, USA - Ann Vasc Surg.).


Effective Combination of Lymphatico-Venous Anastomosis and Negative Pressure Wound Therapy for Lymphocyst: A Case Study - Nih.gov
Abstract by Ayano Shimono, Hisashi Sakuma, Shiho Watanabe and Hikaru Kono (Japan - J Obstet Gynaecol Res.).


The Impact of Copper Impregnated Wound Dressings on Surgical Site Infection Following Caesarean Section: A Double Blind Randomised Controlled Study - Nih.gov
Abstract by Linda P Arendsen, R Thakar, P Bassett and A H Sultan (United Kingdom - Eur J Obstet Gynecol Reprod Biol.).


Hyperbaric Oxygen Therapy Eases Persistent Postconcussion Symptoms - Medscape.com
Article by Megan Brooks. Hyperbaric oxygen therapy (HBOT) markedly reduces multiple symptoms of persistent postconcussion syndrome (PPCS) following mild traumatic brain injury (mTBI), results from a randomized controlled crossover study show.


Negative Pressure Wound Therapy Combined With Instillation for Sternoclavicular Joint Infection - Nih.gov
Article by Waldemar Schreiner, Ingo Ludolph, Wojciech Dudek, Raymund E Horch and Horia Sirbu (Erlangen-Nuremberg, Germany - Ann Thorac Surg.)


Negative Pressure Wound Therapy for Deep Sternal Wound Infections: Microbiological Characteristics and Antibiotic Resistance - Nih.gov
Abstract by Yu V Belov, A N Kosenkov, I A Vinokurov and A Al-YOusef (Moscow, Russia - Khirurgiia).


Pediatric Tracheostomy Wound Healing: A Retrospective Cohort Study - Nih.gov
Abstract by Brian H Odom, Charlotte Yates, Leah Lowe and Lisa VanHoose (USA - Adv Skin Wound Care).


Utilizing Negative Pressure Wound Therapy with Instillation (NPWT-i) to Achieve Source Control of Complex Aeromonas Hydrophilus Necrotizing Infection Following a Traumatic Amputation - Woundcarelearningnetwork.com
Poster by Richard Hill. The usage of NPWT-i gives clinicians the option to achieve source control in complex wounds with active, myonecrotic infection through bactericidal solution instillation.


Human interleukin-4–treated regulatory macrophages promote epithelial wound healing and reduce colitis in a mouse model - Sciencemag.com
Article by Timothy S. Jayme, Gabriella Leung, Arthur Wang, Matthew L. Workentine, Sruthi Rajeev, Adam Shute, Blanca E. Callejas, Nicole Mancini, Paul L. Beck, Remo Panaccione and Derek M. McKay (Canada).


Hypertrophic Scars and Keloids: Overview of the Evidence and Practical Guide for Differentiating Between These Abnormal Scars - Nih.gov
Abstract by G C Limandjaja, F B Niessen, R Scheper and S Gibbs (Amsterdam, The Netherlands - Exp Dermatol.).


Re-suturing of Puerperal Perineal Wound: An Assessment of Indications, Risk Factors and Outcomes - Nih.gov
Abstract by Reut Rotem, Hen Y Sela, Orna Reichman, Adi Y Weintraub, Sorina Grisaru-Granovsky and Misgav Rottenstreich (Israel - Eur J Obstet Gynecol Reprod Biol.).


Novel Fenugreek Gum-Cellulose Composite Hydrogel With Wound Healing Synergism: Facile Preparation, Characterization and Wound Healing Activity Evaluation - Nih.gov
Abstract by Yudi Deng, Xushan Yang, Xudong Zhang, Hehe Cao, Lianzhi Mao, Miaomaio Yuan and Wenzhen Liao (China - Int J Biol Macromol.).


Evaluate the Effect of Zinc Oxide and Silver Nanoparticles (ZnO-Ag NPs) on Biofilm and icaA Gene Expression in Methicillin-Resistant Staphylococcus Aureus (MRSA) Isolated From Burn Wound Infection - Nih.gov
Abstract by Ali Shakerimoghaddam , Delaramsadat Razavi, Farzaneh Rahvar, Maria Khurshid, Shokoufeh Moghadam Ostadkelayeh, Seyed-Alireza Esmaeili, Azad Khaledi and Mohsen Eshraghi (Iran - J Burn Care Res.).


When A Patient Presents With Limb-Threatening Necrotizing Fasciitis - Podiatrytoday.com
Presenting a case of a 64-year-old male with diabetes who developed a limb-threatening infection after dropping boiling tea on his left foot, this author shares insights on the aggressive treatment regimen and multidisciplinary care that enabled the patient to return to normal activities in four months.


Improvement in Mechanical Properties and Biodegradability of PLA Using Poly(ethylene Glycol) and Triacetin for Antibacterial Wound Dressing Applications - Nih.gov
Abstract by Bita Darabian, Hamed Bagheri and Soheila Mohammadi (Iran - Prog Biomater.).


Healing of Full-Thickness Murine Skin Wounds Containing Nanofibers Using Splints for Efficient Reepithelialization and to Avoid Contracture - Nih.gov
Abstract by Nilika Bhattacharya, Arup K Indra and Gitali Ganguli-Indra (USA - Method Mol Biol.).


Synergistic Effect and Antibiofilm Activity of a Skin and Wound Cleanser - Woundresearch.com
Article by Ann Beal Salamone, Joseph C. Salamone, Rebecca Erin McMahon, Suprena Poleon, Nina Bionda and Peter D’Arpa (USA)


A Bio on Biofilm - Woundcarelearningnetwork.com
Article by Seth Snowden. When bacteria, fungi, and other microorganisms are introduced into a wound as a result of contact between the wound and a contaminated source, the microorganisms can begin to take residence. The individual bacterial cells inhabiting the wound begin to produce and release substances that, with time, meld together and collectively create a biofilm.


A Novel Biofilm Disruptive Agent Influences the Wound Healing Process by Altering the Level of Cytokines and Chemokines Within the Wound - Woundcarelearningnetwork.com
Poster. Wound healing occurs through specific overlapping steps involving different host cell types and mediated by cytokines and chemokines (C/C) with pleiotropic functions. We previously showed by H&E staining that treatment with the novel antimicrobial biofilm disruptive agent (BDA) decreased inflammation on day 1 post-injury (D1), increased angiogenesis and granulation tissue formation on D3, and enhanced keratinocyte hyperplasia on D7.


Combination Therapy of Oxidised Regenerated Cellulose/Collagen/Silver Dressings With Negative Pressure Wound Therapy for Coverage of Exposed Critical Structures in Complex Lower-Extremity Wounds - Nih.gov
Abstract by Mei Ling Loh, Benjamin K L Goh, Yuan Kong, George Varughese, Jia Lin Ng, Zhiwen J Lo and Chong Han Pek (Singapore - Int Wound J.).


Inpatient Versus Outpatient Management of Negative Pressure Wound Therapy in Pediatric Patients - Nih.gov
Abstract by Katherine B Santosa, Alexandra M Keane, Matt Keller, Margaret A Olsen, Erika D Sears and Alison K Snyder-Warwick (USA - J Surg Res.).


Improved Surface Adhesion and Wound Healing Effect of Madecassoside Liposomes Modified by Temperature-Responsive PEG-PCL-PEG Copolymers - Nih.gov
Abstract by Meifeng Liu, Weichi Chen, Xingyu Zhang, Pengwen Su, Feng Yue, Shaoqun Zeng and Song Du (China - Eur J Pharm Sci.).


The NPWT Switch Worth Making: Learn How a Hospital System Succesfully Transitioned to a New NPWT System - Woundresearch.com
A 5:30 video by Carol Davis.


Single-stage Biomatrix and Skin Graft Under a Single-patient Portable NPWT Device Decreases Hospital Costs - Woundresearch.com
A 5:01 video by Charles K. Lee. („Egylépéses biomátrix és bőrátültetés egybeteges hordozható NPWT-eszközzel csökkenti a kórházi költségeket”)


A Closer Look at Hyperbaric Safety and Training - Todayswoundclinic.com
Article by W. T. Workman.


Unraveling Compression Science - Woundcarelearningnetwork.com
Article by Suzie Ehmann.


The Effects of Nitrofurazone on Wound Healing in Thoracoabdominal Full-thickness Skin Defects - Woundresearch.com
Article by Sami Karapolat, Banu Karapolat, Alaaddin Buran, Burcu Kemal Okatan, Atila Turkyilmaz, Turan Set and Celal Tekinbas (Trabzon, Turkey).


High Potential for Complications After Traumatic Exposure in Patients With a Total Knee Replacement - Woundresearch.com
Article by Camilo Partezani Helito, Marcel Faraco Sobrado, Marco Aurelio Cotegipe Negrelli, José Ricardo Pécora, Riccardo Gomes Gobbi and Fabio Janson Angelini (Brazil).


Efficacy of a Urinary Bladder Matrix for Treating Wound Dehiscence With Hardware Exposure in a Patient With Rheumatoid Arthritis - Woundresearch.com
Article by Roger D. Bui, Kenrick Lam and Vinod K. Panchbhavi (Galveston, USA).


Mutual inter-regulation between iNOS and TGF-β1: Possible molecular and cellular mechanisms of iNOS in wound healing - Sciencedirect.com
Abstract by Seham A. Abd El-Aleem, Hanaa Hassanein Mohammed, Entesar Ali Sabera, Azza S. Embaby and Laiche Djouhri (Egypt, Quatar - Biochimica et Biophysica Acta).


ETH researchers deconstruct tissue repair - Ethz.ch
ETH researchers have deconstructed the mechanisms that control wound healing and scar formation in more detail. To this end, biologists and engineers have developed a new method that allows the biomechanical properties of the healing tissue to be measured in vivo for the first time.


Result of the 2020 Council election - Ewma.org
The following candidates were elected by the individual members: Samantha Holloway, UK (Re-election); Elena Conde Montero, Spain; Pedro Pancorbo-Hildago, Spain (Re-election); Luc Teot, France (Re-election); Evelien Touriany, Belgium (Re-election).


Effect of photobiomodulation on cellular migration and survival in diabetic and hypoxic diabetic wounded fibroblast cells - Springer.com
Abstract by Sandy W. Jere, Nicolette N. Houreld and Heidi Abrahamse (South Africa - Lasers in Medical Science).


Skin Remodeling and Wound Healing in the Gottingen Minipig Following Exposure to Sulfur Mustard - Nih.gov
Abstract by Jeffrey D Laskin, Gabriella Wahler, Claire R Croutch, Patrick J Sinko, Debra L Laskin, Diane E Heck and Laurie B Joseph (USA - Exp Mol Pathol.).


Trace amines produced by skin bacteria accelerate wound healing in mice - Nature.com
Article by Arif Luqman, Muhammad Zainul Muttaqin, Sumah Yulaipi, Patrick Ebner, Miki Matsuo, Susanne Zabel, Paula Maria Tribelli, Kay Nieselt, Dewi Hidayati and Friedrich Götz (Germany, Indonesia, Argentina - Communications Biology)


That Time You Honestly Told Your Daughter About Therapy and Wound Care - Todayswoundclinic.com
Article by Frank Aviles Jr. (USA).


Preoperative Japanese Society for the Surgery of the Foot Lesser toe score and erythrocyte sedimentation rate influence wound healing following rheumatoid forefoot surgery - Tandfonline.com
Article by Koji Ohta, Jun-ichi Fukushi, Satoshi Ikemura, Satoshi Kamura, Hisa-aki Miyahara and Yasuharu Nakashima (Japan - Journal Modern Rheumatology).


Mussel-inspired Dual-crosslinking Hyaluronic Acid/ε-polylysine Hydrogel with Self-healing and Antibacterial Properties for Wound Healing - Acs.org
Abstract by Shuai Liu, Xin Liu, Yanhan Ren, Peng hui Wang, Yajie Pu, Rong Yang, Xiaoxue Wang, Xiao yan Tan, Zhiwen Ye, Victor Maurizot and Bo Chi (CS Appl. Mater. Interfaces).


The proinflammatory cytokines IL‐1β and TNF‐α modulate corneal epithelial wound healing through p16Ink4a suppressing STAT3 activity - Wiley.com
Abstract by Xiaolei Wang, Songmei Zhang, Muchen Dong, Yunqiu Li, Qingjun Zhou and Lingling Yang (China - Journal of Cellular Physiology).


Natural SIRT1 modifiers as promising therapeutic agents for improving diabetic wound healing - Sciencedirect.com
Abstract by Pranav Kumar Prabhakar, Karmveer Singh, Dhiraj Kabra and Jeena Gupta (India - Phytomedicine).


Batch Preparation of Electrospun Polycaprolactone/Chitosan/Aloe Vera Blended Nanofiber Membranes for Novel Wound Dressing - Nih.gov
Abstract by Jing Yin and Lan Xu (Suzhou, China - Int J Biol Macromol.).


Mechanisms Involved in the Development and Healing of Diabetic Foot Ulceration - Medscape.com
Abstract by Thanh Dinh; Francesco Tecilazich; Antonios Kafanas; John Doupis; Charalambos Gnardellis; Ermelindo Leal; Ana Tellechea; Leena Pradhan; Thomas E. Lyons; John M. Giurini and Aristidis Veves (USA, Greece).