Hungarian Wound Care Society

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News from the field of wound care and wound healing - March, 2020

Spray-On Gene Therapy With RenovaCare SkinGun™ in New Study Underway at King’s College London - Apnews.com
RenovaCare, Inc., developer of patented technologies for spraying self-donated stem cells for the regeneration of skin and other organs and tissues, today announced that the Company’s novel SkinGun™ is now being used to apply regenerative cells in a preclinical study of new gene therapies, underway at King’s College London. Researchers are using the SkinGun™ to ultra-gently spray gene-supplemented cells for accelerated wound healing in Recessive Dystrophic Epidermolysis Bullosa (RDEB), a debilitating skin disease which afflicts young children and leads to premature death.


Practical Things You Should Know about Wound Healing and Vacuum-Assisted Closure Management - Nih.gov
Abstract by Singh D., Chopra K., Sabino J., Brown E. (USA) from Plast Reconstr Surg.


Status and Future Scope of Hydrogels in Wound Healing: Synthesis, Materials and Evaluation - Sciencedirect.com
Abstract by Jinxi Xiang, Lan Shen and Yanlong Hong (Shanghai, China).


Custom Clotting Particles Could Help Heal Chronic Wounds - Ncsu.edu
NC State inventors have developed preformed fibrin that mimics the body’s natural clotting process, which could enhance treatment outcomes in chronic wounds.


Skin wound healing triggers epigenetic modifications of histone H4 - Biomedcentral.com
Article by Carlos H. V. Nascimento-Filho, Ericka J. D. Silveira, Eny M. Goloni-Bertollo, Lelia Batista de Souza, Cristiane H. Squarize and Rogerio M. Castilho (USA-Brasil).


Treating Chronic Pain With Lasers - Painnewsnetwork.com
Months after surgery for my badly broken foot, the last scab finally fell off, revealing to my horror that the surgical incision had not closed. I have Ehlers-Danlos Syndrome (EDS), a genetic condition that prevents my body from building proper collagen. Poor wound healing is a common complication for people like me.


Wound Healing in the Womb - Sciencemag.org
Downloadable article by P. J. Skerrett which was published in the May 24, 1991 issue of Science.


Antimicrobial and anti-inflammatory potential of Angelica dahurica and Rheum officinale extract accelerates wound healing in Staphylococcus aureus-infected wounds - Nature.com
Article written by Wan-Ting Yang, Chun-Yen Ke, Wen-Tien Wu, Yi-Hsiung Tseng and Ru-Ping Lee.


Randomised trial of skin cell suspension confirms efficacy for healing of venous ulcers - Iwoundsnews.com
Use of autologous skin cell suspension (ASCS) in addition to compression has been shown to accelerate healing in large venous leg ulcers (VLUs), according to the results of a multicentre randomised trial conducted in the UK.


Lipid helps heal the eye's frontline protection - Eurekalert.org
A species of a lipid that naturally helps skin injuries heal appears to also aid repair of common corneal injuries, even when other conditions, like diabetes, make healing difficult, scientists report.


How tissues harm themselves during wound healing - Eurekalert.org
Researchers from Osaka University identify the protein Rbm7 as a novel regulator of the development of tissue fibrosis.


Closed Incision Negative Pressure Wound Therapy in the Management of a Complex Fasciotomy Wound in a Pediatric Patient - Cureus.com
Full article written by Gordon Lee, Patrick C. Murray and Ian G. Hasegawa


Formulation and Evaluation of the Wound Healing Chitosan Gel of Povidone Iodine - Researchgate.net
Following the above link you can request the .pdf version of the article written by Ashwani Mishra, Subhash Pande and Anupam Kumar Pathak.


Urea for Wound Healing - Jamanetwork.com
Downloadable article of C. J. Elmore's article from 1938.


New graphene patch for remote wound monitoring - Medical.net
French scientists at the Neel Institute have produced a graphene patch that records the condition of chronic wounds, such as ulcers suffered by the elderly or those with diabetes, at any time. The data can be sent from home to the hospital via mobile phone, facilitating a rapid response to possible infections.


pdf (1,1 mB)!
Negative pressure wound therapy compared with standard moist wound care on diabetic foot ulcers in real-life clinical practice: results of the German DiaFu-RCT - Bmj.com
Downloadable article of Dörthe Seidel, Martin Storck, Holger Lawall, Gernold Wozniak, Peter Mauckner, Dirk Hochlenert, Walter Wetzel-Roth, Klemens Sondern, Matthias Hahn, Gerhard Rothenaicher, Thomas Krönert, Karl Zink and Edmund Neugebauer.


Negative Pressure Wound Therapy Devices Market 2019 Industry Trends, Opportunities and... - Monroescoop.com
With having published myriads of reports, Negative Pressure Wound Therapy Devices Market Research imparts its stalwartness to clients existing all over the globe. Our dedicated team of experts deliver reports with accurate data extracted from trusted sources. We ride the wave of digitalization – facilitate clients with the changing trends in various industries, regions and consumers. You can buy this report.


Study shows how skin cells change when preparing to heal wounds - Drugtargetreview.com
The researchers hope their study into how cellular heterogeneity changes as the skin heals wounds will allow further research into pathological conditions that cause poor wound healing.


What You Need to Know About Vacuum-Assisted Wound Closure (VAC) - Healthline.com
Vacuum-assisted closure (VAC) is a method of decreasing air pressure around a wound to assist the healing. It’s also referred to as negative pressure wound therapy. During a VAC procedure, a healthcare professional applies a foam bandage over an open wound, and a vacuum pump creates negative pressure around the wound.


pdf (300 kB)!
Microgravity and Cell Adherence - Mdpi.com
Downloadable article of Johann Bauer (Max Planck Institute f. Biochemistry, Martinsried, Germany)


Phagocytosis of Wnt inhibitor SFRP4 by late wound macrophages drives chronic Wnt activity for fibrotic skin healing - Sciencemag.org
Article written by Denise Gay†, Giulia Ghinatti, Christian F. Guerrero-Juarez, Rubén A. Ferrer, Federica Ferri, Chae Ho Lim, Shohei Murakami, Nathalie Gault, Vilma Barroca, Isabelle Rombeau, Philippe Mauffrey, Lamya Irbah, Elsa Treffeisen, Sandra Franz, Alexandre Boissonnas, Christophe Combadière, Mayumi Ito, Maksim V. Plikus and Paul-Henri Romeo.


Wound healing activity of a traditional Chinese medicine (Longxuejie) in capsule dosage form - Physiciansweekly.com
This study was designed to investigate the wound healing effects of a Traditional Chinese Medicine (Longxuejie) combined with dragon’s blood capsule. A total of 80 patients with ulcerative bedsore observed in our hospital department of Geriatrics were selected from May 2016 to May 2017. (abstract)


Defying Hard-to-Heal Wounds with an Early Antibiofilm Intervention Strategy: Wound Hygiene - Woundsource.com
This international consensus document provides an overview of biofilm formation and its role in delayed wound healing, the epidemiology of chronic wounds, and the burden of non-healing wounds on quality of life, on health care use, and on financial resources.


New UCI-led study reveals how skin cells prepare to heal wounds - Som.uci.edu
A team of University of California, Irvine researchers have published the first comprehensive overview of the major changes that occur in mammalian skin cells as they prepare to heal wounds. Results from the study provide a blueprint for future investigation into pathological conditions associated with poor wound healing, such as in diabetic patients.


Chronic venous insufficiency identified as a leading cause of lower extremity lymphoedema - Iwoundsnews.com
A retrospective analysis of patients diagnosed with lower extremity lymphoedema, and treated in a cancer-affiliated physical therapy department, has found that chronic venous insufficiency (or phlebolymphoedema) is the "predominant cause of lower extremity lymphoedema".


An injectable photopolymerized hydrogel with antimicrobial and biocompatible properties for infected skin regeneration - Nature.com
Article of Ao Sun, Xinye He, Lang Li, Tao Li, Qinya Liu, Xinli Zhou, Xiao Ji, Wei Li and Zhiyong Qian.


Wound Closure Strips Market - Micro-anchor Skin Closures to Fuel Market Growth - Biospace.com
According to the report, the global wound closure strips market was valued at US$ 250 Mn in 2018 and is projected to expand at a CAGR of ~7% from 2019 to 2027. Wound closure ensures and accelerates wound healing by protecting the site and influencing migration of keratinocytes over the granulation tissue. Wound closure strips are porous surgical tape strips, which can be used to close small wounds.


Adipose stem cells isolated from diabetic mice improve cutaneous wound healing in streptozotocin-induced diabetic mice - Biomedcentral.com
Downloadable article of Ran An, Yong Zhang, Yu Qiao, Lili Song, Hongjun Wang and Xiao Dong.


How can bioinspired nanofibers regenerate skin and aid wound healing? - Avancedsciencenews.com
Electrospinning is an emerging fabrication technology that has attracted a lot of attention in recent years in fields ranging from medicine and tissue engineering to energy and environmental science due to the ease of producing well-defined, fibrous woven or non-woven materials. The process begins when a polymer solution or melt is exposed to a high electric field that causes it to deform and spin, and manipulates it to very fine meshes of micro/nanostructured fibers.


Wound Healing Market Trends, Key Players, Overview, Competitive Breakdown and Regional 2025 Forecast - Nysenewstimes.com
The key objective of “Wound Healing Market 2020-2025 Trends and Global Insights” report is to help the user understand the market in terms of its segmentation, influential trends, leading players, market potential, primary and secondary research, and the challenges that the market is facing.


Enzymatic Wound Debridement Market Analysis by Size, Share, Growth, Trends up to 2027 - 3wnews.org
Enzymatic wound debridement includes the application of proteolytic enzymes to wound in order to accelerate to remove necrotic tissue and control digestion. It is a chemical reaction (hydrolysis) which involves the degradation of proteinaceous devitalized tissue. Enzymatic debriding agents are used along with moist wound healing agents which aids the autolytic debridement process.


Skin Care Benefits From Honey- Based Products - Stylenest.co.uk
Honey has been used in medicine since Ancient Egypt, mostly due to its wound-healing properties and antibacterial action. However, its antimicrobial features are also regularly used in the beauty industry. When applied to your skin, Honey creates an invisible shield to fight all the acne-causing bacteria, damage, and environmental factors.


Diabetic Foot Ulcers and Pressure Ulcers Market trends, supply and demand with global forecast 2020-2026 just published: Medtronic PLC, Acelity L.P., 3M Healthcare,Smith & Nephew PLC - Newskangaroos.com
The research study covers the key players in the market and their major role in the market for the present and future prospective. The Diabetic Foot Ulcers and Pressure Ulcers market report delivers insights and expert analysis of key market players' strategies in the market. The market report provides an extensive analysis of the realistic data of the Diabetic Foot Ulcers and Pressure Ulcers market.


Hyperbaric Oxygen Effective Option For Non Healing Chronic Diabetic Foot Ulcers - Medicaldialogues.in
Hyperbaric Oxygen has been found to have a tremendous role in wound healing in refractory diabetic ulcers, finds a new study.


Interdisciplinary wound care teams are integral for CLTI patients' care, ISET session concludes - Iwoundsnews.com
The 32nd International Symposium on Endovascular Therapy (ISET; 22–25 January, Hollywood, USA) had a particular focus on treating critical limb-threatening ischaemia (CLTI). In the session “Improving outcomes and prognosis for CLI”, conference attendees learnt about the global scale of the disease, the importance of adequate wound care post-treatment, and the possibility of revascularisation in the outpatient environment.


Effects of Topical Insulin on Wound Healing: A Review of Animal and Human Evidences - Dovepress.com
Downloadable article of Jiao Wang and Jixiong Xu (Nanchang, China).


Assessment of Acceptability and Ease of Use of Haemoglobin Spray (Granulox®) in the Management of Chronic Wounds - Dovepress.com
Downloadable article of Knut Kröger, Gabor Gäbel and Benjamin Juntermanns (Krefeld, Germany).


Wound Measurement Market to Receive Overwhelming Hike in Revenues by 2020-2025... - Openpr.com
Global Wound Measurement market would thus note a steady growth over the forecast period of 2020 - 2025. The robust CAGR (Compound Annual Rate Growth) will chart an upward growth curve and create lucrative growth opportunities in the global Wound Measurement market.


ECRG4 regulates neutrophil recruitment and CD44 expression during the inflammatory response to injury - Sciencemag.org
Article from California written by Robert A. Dorschner, Jisook Lee, Olga Cohen, Todd Costantini, Andrew Baird and Brian P. Eliceiri.


A statistical inference approach to reconstruct intercellular interactions in cell migration experiments - Sciencemag.org
Italian-French article written by Elena Agliari, Pablo J. Sáez, Adriano Barra, Matthieu Piel, Pablo Vargas and Michele Castellana.


Can a cannabis-based medicine applied to a non-healing wound improve healing and reduce pain? - Isrctn.com
Wound healing is a serious problem worldwide. Non-healing wounds lead to reduced quality of life, limb amputation, increased death rates, and losses in human productivity. They can also lead to increased opioid use (and potential addiction) and antibiotic resistance.


Wound Debridement Market Size, Share, Trends, Segmentation and Forecast to 2027 - 3wnews.com
The “Global Wound Debridement Market Analysis to 2027” is a specialized and in-depth study with a special focus on the global market trend analysis. The report aims to provide an overview of wound debridement with detailed market segmentation by product type, therapy and geography.


Iran Develops Antibacterial Wound Dressing Curbing Red Blood Cell Disruption - Ifpnews.com
Iranian scientists have fabricated an alginate fibrous wound dressing with antibacterial and wound healing properties that can decrease disruption of red blood cells in the wound bed.


Modified Usage of Negative Pressure Wound Therapy for the Management of Severe Deep Fascial Space Infections in the Head and Neck - Dovepress.com
Downloadable article of Jian Cao, Zhixu Liu, Dongyang Ma, Shunyao Shen and Xudong Wang.


RedDress Announces Launch of ActiGraft, FDA-Cleared for the Treatment of Chronic and Acute Wound Types - Newkerala.com
RedDress, a privately held, Israel and U.S. based company, announced the U.S. launch of ActiGraft, the first wound treatment that transforms - in real time - a patient's blood into an autologous whole blood clot tissue.


Cold Plasma Market is projected to reach a market value of by US$ 51,314.6 Mn by 2026 end - Lakeshoregazette.com
With the advancing electronics and semiconductors industry, the demand for cold plasma (CP) has been on the rise. While cold plasma applications in sterilization and disinfection are currently accounting for maximum revenue in the cold plasma market, rapidly emerging applications in wound healing and adhesion will reportedly create lucrative opportunities for stakeholders.


pdf (1 mB)!
Review on Wound Healing Therapeutic Regimens in Ayurveda - Ijapr.in
Pdf version of the article of B. Venkateshwarlu, C. Muralikrishna, K. Midhuna Mohan, K. Anumol and G. Babu.


Hydrogel Dressings Market 2020 | Industry Growth Rate, Latest Trends, Opportunities & Challenges, Demand and Analysis Forecast to 2024 - Kpmnews.com
The "Hydrogel Dressings Market" report is a valuable source of perceptive data for business strategists that provides the industry overview with growth analysis and historical & futuristic cost, revenue, demand and supply data.


Evaluation of the In Vitro Wound-Healing Activity and Phytochemical Characterization of Propolis and Honey - Mdpi.com
A downloadable paper by Alexandra M. Afonso, Joana Gonçalves, Ângelo Luís, Eugenia Gallardo and Ana Paula Duarte.


A New Handheld 3D Printer Treats Severe Burns - Thomasnet.com
Researchers from the University of Toronto have created a revolutionary handheld 3D printer, but this one is no 3Doodler. The handheld device 3D prints skin and it could help heal patients suffering from severe burns.


Rising Prevalence of Orthopedic Ailments to Propel Bone Wax Market - Biospace.com
Bone wax is a product that enhances wound healing by aiding in hemostasis, i.e. the process of causing bleeding to stop. Bone wax usually comprises of roughly 70% beeswax and 30% of softening agents. The softening agents used are typically oils, petrolatum, paraffin wax and palmitates.


Global Wound Healing Market 2020 Business Scenario – Smith & Nephew, Integra LifeSciences, B. Braun Melsungen, Mölnlycke Health Care, 3M,etc - Nysenewstime.com
"Global Wound Healing Market 2020" analyses the Top Companies Business Insights, Industry Share, Market Size, Products, Applications, Sales-Revenue and Regional Analysis. The total market is further divided into market drivers, trends, strategies, dynamics, market outlook and forecast to 2026.


Deep venous stenting presents advantage over ablation in achieving better ulcer healing rates - Venousnews.com
Venous leg ulcers (VLUs) secondary to deep venous stenosis represent a distinct class of patients who require a unique treatment paradigm, argued Abhishek Mohapatra (University of Pittsburgh Medical Center, Pittsburgh, USA), presenting results of a retrospective study of patients presenting with VLUs—between 2013 and 2017—that favoured deep venous stenting over ablation techniques.


Wound Irrigation Solution Market Detailed Analysis and Forecast 2018-2028 - Monroescoop.com
Wound irrigation refers to a procedure undertaken in the course of a variety of standard wound healing techniques that works by supplying a steady stream of a medicated solution to an open wound surface to assist with more reliable visual examination of the wound, to remove deeply located debris, and achieve wound hydration. The goal of wound irrigation is chiefly to clean the wound while avoiding any further damage or trauma to the wound bed while also minimizing the risk of further introducing pathogens into the wound bed.


Smart bandage technology could push wound care into the future - Aiin.healthcare
AI-powered smart bandages could soon be used to treat severe wounds, monitoring the healing process and delivering various stimuli when appropriate, according to researchers from the University of California Santa Cruz (UCSC).


CutisCare Launches Technology to Improve Patient Access to Wound Care - Digitaljournal.com
The CareAccel™ Growth Acceleration platform is a mobile and desktop application designed with clinical education best practices in mind. The technology gives program directors the data and intelligence to identify healthcare providers in the community that have a propensity for treating patients with chronic wounds. Through trip planning, real-time entry and reporting, and an interactive mapping interface, program directors are able to more efficiently and effectively plan their activities to reach more healthcare providers.


Researchers identify protein critical for wound healing after spinal cord injury - Eurekalert.org
Plexin-B2, an axon guidance protein in the central nervous system (CNS), plays an important role in wound healing and neural repair following spinal cord injury (SCI), according to research conducted at the Icahn School of Medicine at Mount Sinai and published today in Nature Neuroscience. The study's findings could aid the development of therapies that target axon guidance pathways for more effective treatment of SCI patients.


Smart Bandage Research Uses mHealth to Improve Wound Healing, Care - Mhealthintelligence.com
Researchers are working on a smart bandage that would use a combination of mHealth, telehealth, AI and regenerative medicine to improve wound healing and care management.


Prevention and Treatment of Diabetic Foot Ulcers May Benefit From Multimodal Approach - Dermatologyadvisor.com
Diabetic foot ulcers continue to be a major cause of morbidity and mortality in patients with diabetes despite several standard of care options. A paper published in the American Journal of Clinical Dermatology highlights new trends in the management of diabetic foot ulcers, including the use of adjunctive therapies.


How bioelectronic medical devices are transforming modern healthcare - Pharmafield.co.uk
Every 37 seconds someone in the western world dies from a venous thromboembolism (VTE). In England, this equates to approximately 40,000 deaths each year. 62% of these deaths are deemed preventable given the proper treatment1 and around 30% of those who have suffered will likely endure further health problems within the next 10 years of their life.


Negative Pressure Wound Therapy Devices Market Size, Share, Growth, Trends, Segmentation and Forecast by 2025 - Nysenewstimes.com
Negative pressure wound therapy devices is a medical procedure in which a vacuum dressing is used to enhance and promote wound healing in acute, chronic and burn wounds. It involves the use of a sealed wound dressing attached to a pump to create a negative pressure environment in the wound. Applying continued vacuum helps to increase blood flow to the area and draw out excess fluid from the wound. the vacuum can either be applied continuously or intermittently based on the wound type or location.


Multi-Layered Polyamide/Collagen Scaffolds with Topical Sustained Release of N-Acetylcysteine for Promoting Wound Healing - Dovepress.com
Downlodable paper of Jinfei Hou, Lifeng Chen, Muran Zhou and colleagues.


Surgical Sutures Market 2026 Global Industry Size, Share, Growth - CP Medical, Inc., BSN Medical, DemeTech Corporation, Ethicon, Inc. and More - Digitaljournal.com
The global surgical sutures market is expected to rise at a CAGR of 6.0% between 2017 and 2025 majorly owing to the rising number of surgical procedures. Fortune Business Insights in a report, titled "Surgical Sutures: Global Market Analysis, Insights and Forecast, 2018-2025" provides valuable information on the factors enabling growth in the market.


Yarn Made from Human Tissue Helps Repair Wounds - Hospimedica.com
Yarn grown from human skin cells can be knitted, crocheted, and sewed to create pouches, valves, and tubes, and even perforated membranes, according to a new study.


Critical Timing: The Inflammatory Phase of Wound Healing - Woundsource.com
Wound healing is a complex biological process that involves a sequence of molecular and cellular events to restore damaged tissue. These events occur within the extracellular matrix, a complex three-dimensional acellular environment that is present within all tissue and essential for life.


Advanced Therapies for Wound Management: The Role of Collagen - Woundsource.com
Wound chronicity is an ongoing challenge for patients and health care professionals around the globe. An astonishing 4.5 million people in the United States experience lower extremity wound chronicity, while an estimated 1% are affected in the Western population with all types of chronic wounds.


InDex Pharmaceuticals Publishes Mechanism of Action Data for Cobitolimod in Scientific Journal - Yahoo.com
InDex Pharmaceuticals Holding AB (publ) today announced the publication of scientific data on the mechanism of action of cobitolimod, the company's lead drug candidate in development for the treatment of moderate to severe ulcerative colitis. The paper, published in the peer-reviewed Journal of Crohns and Colitis (JCC), shows that the Toll-like receptor 9 (TLR9) agonist cobitolimod can modulate the immune system in ulcerative colitis by balancing the mucosal Th17/Treg cell response.


Advanced Wound Care Market Size was Valued at USD 8,457 Million in 2018 and Grow at a CAGR of 6.5% by 2019 to 2026 - Yahoo.com
Wound care is categorized into two types namely traditional wound care (TWC) and advanced wound care (AWC). Advanced wound care products (AWC) are designed for treating acute & chronic wounds. Chronic wounds take longer to heal and are expensive to treat.


ILS’ turmeric-based wound healing drug to hit markets soon - Orissapost.com
The Institute of Life Sciences (ILS), transferred a technology for production of curcumin sponge for wound healing for commercialisation on the concluding day of a conclave on ‘Science and Technology Interventions for Welfare of Tribal Population’ at the institute premises here.


Inflammation Prevention, Wound Healing And Building Immunity - Reasons Why You Need Zinc - Ndtv.com
Zinc is an important micronutrient for the body. The body cannot produce or store zinc and thus it is important that you get it from your diet. Some important functions that presence of zinc plays in our body are: DNA synthesis, growth and development, wound healing, immune function, gene expression, enzymatic reactions and protein synthesis.