Chronic Inflammation in Non-Healing Skin Wounds and Promising Natural Bioactive Compounds Treatment - Mdpi.com
Article by Priscila Schilrreff and Ulrike Alexiev (Berlin, Germany - IJMS).
The authors focus on natural compounds with antioxidant, anti-inflammatory, and antibacterial activities and their mechanisms of action, as well as on recent wound treatments and therapeutic advancements capitalizing on nanotechnology or new biomaterial platforms.
Antioxidant and Wound Healing Potential of Vitis vinifera Seeds Supported by Phytochemical Characterization and Docking Studies - Mdpi.com
Article by Tarfah Al-Warhi, Eman Maher Zahran, Samy Selim, Mohammad M. Al-Sanea, Mohammed M. Ghoneim, Sherif A. Maher, Yaser A. Mostafa, Faisal Alsenani, Mahmoud A. Elrehany, Mohammed S. Almuhayawi, Soad K. Al Jaouni, Usama Ramadan Abdelmohsen and Abeer H. Elmaidomy (Saudi Arabia, Egypt - Antioxidants).
The authors' highlights the potential of V. vinifera seed extract in wound repair uncovering the most probable mechanisms of action using in silico analysis.
Topical application of sustained released-carbon monoxide promotes cutaneous wound healing in diabetic mice - PubMed
Abstract by Tomohisa Takagi, Tetsuya Okayama, Jun Asai, Katsura Mizushima, Yasuko Hirai, Kazuhiko Uchiyama, Takeshi Ishikawa, Yuji Naito and Yoshito Itoh (Kyoto, Japan - Biochem Pharmacol.).
Establishment of an In Vitro Scab Model for Investigating Different Phases of Wound Healing - Mdpi.com
Article by Chao Liu, Helen Rinderknecht, Tina Histing, Jonas Kolbenschlag, Andreas K. Nussler and Sabrina Ehnert (Tübingen, Germany - Bioengineering).
The established in vitro scab model can be used to analyze the first phases of wound healing where blood and skin cells interact, as it is viable and responsive for more than 2 weeks.
Hyperbaric Oxygen Therapy in the Management of Chronic Wounds - Clinicaladvisor.com
Article by Blakley Sproles, Thomas Colletti, Michael R. Cook, David G. Cox and Jenna Rolfs (Lynchburg, USA).
Research suggests that optimal clinical outcomes and quality of life can be obtained with use of hyperbaric oxygen therapy in applicable candidates while also reducing the burden of health care expenditures on the treatment of chronic wounds.
Network analysis reveals dysregulated functional patterns in type II diabetic skin - Nature.com
Article by Chunan Liu, Sudha Ram and Bonnie L. Hurwitz (Tucson, USA - Scientific Reports).
Network-based analysis and topological properties allow authors to expand insight into the pathogenesis of T2DM patients to develop skin disorders, which highlights the importance of the system biology approach to study complex diseases. The hub genes and key coordinators may be used as novel therapeutic targets to advance diabetic skin care.
Dressings that use negative pressure for closed surgical wounds - Cochrane.org
Article by Norman G, Shi C, Goh EL, Murphy EMA, Reid A, Chiverton L, Stankiewicz M and Dumville JC.
There is a large number of ongoing studies, the results of which may change the findings of this review. Decisions about use of NPWT should take into account surgical indication and setting and consider evidence for all outcomes.
PDGF-BB-derived supramolecular hydrogel for promoting skin wound healing - Biomedcentral.com
Article by Ke Jian, Chenghao Yang, Tingting Li, Xia Wu, Jun Shen, Jiaying Wei, Zhimou Yang, Dan Yuan, Mingyi Zhao and Junfeng Shi (China - Journal of Nanobiotechnology).
The authors' results demonstrate that the hydrogel can stimulate collagen deposition and angiogenesis, enhance skin regeneration, and show an excellent therapeutic effect.
Polymerizable Skin Hydrogel for Full Thickness Wound Healing - Mdpi.com
Article by Mairobi Persinal-Medina, Sara Llames, Manuel Chacón, Natalia Vázquez, Marta Pevida, Ignacio Alcalde, Sergio Alonso-Alonso, Laura María Martínez-López, Jesús Merayo-Lloves and Álvaro Meana (Spain - IJMS).
The authors suggest that the polymerizable skin hydrogel is an inexpensive, easy and rapid treatment that could be transferred into clinical practice in order to improve the treatment of skin wounds.
Observations by health care professionals about wound healing in Ghanaian patients who skin-bleach - Wiley.com
Article by Okensama M La-Anyane, Richard S Feinn, David J Hill, Lynn Copes, Gifty Kwakye and Bernard K Seshie (USA, Ghana - IWJ).
The authors' findings support the anecdotes about observable wound healing impairments in patients who skin-bleach.
Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications - Hindawi.com
Article by Yara Adib, Armand Bensussan and Laurence Michel (France - Mediators of Inflammation).
This review focuses on innate cell populations involved in the initial phase of this orchestrated process, including innate cells from both the skin and the immune system.
Phytotherapy in Diabetic Foot Ulcers: A Promising Strategy for Effective Wound Healing - Tandfonline.com
Abstract by Sonal Sekhar Miraj, Shilia Jacob Kurian, Gabriel Sunil Rodrigues, Kavitha Saravu, Mahadev Rao, Siba Prasad Raychaudhury, Bernard W. Downs and Debasis Bagchi (India, USA - JANA).
Machine Learning-Based Pressure Ulcer Prediction in Modular Critical Care Data - PubMed
Abstract by Petr Šín, Alica Hokynková, Nováková Marie, Pokorná Andrea, Rostislav Krč and Jan Podroužek (Brno, Czech Republic - Diagnostics (Basel)).
Reducing the Incidence and Prevalence of Pressure Injury in Adult ICU Patients with Support Surface Use: A Systematic Review - PubMed
Abstract by Adi Angriawan Bambi, Saldy Yusuf and Andi Masyitha Irwan (Adv Skin Wound Care).
Evaluation of a Gel Containing a Propionibacterium Extract in an In Vivo Model of Wound Healing - Mdpi.com
Article by Campolo M., Gallo G., Roviello F., Ardizzone A., La Torre M., Filippone A., Lanza M., Cuzzocrea S., Siroli L. and Esposito E. (Italy - IJMS).
The results obtained in vivo showed that through local reduction of oxidative stress and inflammation (IL-1β, TNF-α), the Emorsan® Gel significantly reduced the infiltration of mast cells into the injured wound, leading to the amelioration of symptoms such as itch and skin irritation.
A strategy to enable rapid healing and prevent recurrence of venous ulcers - PubMed
Abstract by Kenji Yamamoto, Senri Miwa, Tomoyuki Yamada, Shuji Setozaki, Mamoru Hamuro, Shunji Kurokawa and Sakae Enomoto (Japan - Wounds).
The Future of Burn Care From a Complexity Science Perspective - Silverchair.com
Article by Paul P. M. van Zuijlen, Halil Ibrahim Korkmaz, Vivek M. Sheraton, Tsjitske M. Haanstra, Anouk Pijpe, Annebeth de Vries, Cornelis H. van der Vlies, Eelke Bosma, Evelien de Jong, Esther Middelkoop, Fred J. Vermolen and Peter M. A. Sloot (The Netherlands, Singapore, Russia - Journal of Burn Care & Research).
This paper aims to create awareness of the concept of complexity and to demonstrate the value and possibilities of complexity science methods and tools for the future of burn care through examples from preclinical, clinical, and organizational perspectives in burn care.
Researchers At Mendel University Test New Type of Healing Patches For Burns - Brnodaily.com
Article by Juris Duka. Researchers from the Faculty of Agriculture of Brno’s Mendel University tested a new composition of patches for healing burnt tissue. In collaboration with other institutions, they developed an innovative technique of adding organic nanoparticles with embedded fish oil to the patch base.
Development, characterization and in vivo evaluation of the ointment containing hyaluronic acid for potential wound healing applications - Tandfonline.com
Abstract by Thiago Gomes Figueira, Francisco Vieira dos Santos and Sérgio Akinobu Yoshioka (São Carlos, Brazil - J. of Biomaterials Science).
Improving venous ulcer outcomes - PubMed
Abstract by Laura Bolton (New Brunswick, USA - Wounds).
The value of a biopsy in chronic ulcers: a case series - PubMed
Abstract by Jocelyn Tisch Mendes and Robert J Klein (Greenville, USA - Wounds).
Negative pressure wound therapy versus gauze dressings in managing open fracture wound of lower limbs: A meta-analysis of randomized controlled trials - PubMed
Abstract by Hu Qian, Ting Lei and Yihe Hu (China - Foot Ankle Surg.).
LncRNA XIST accelerates burn wound healing by promoting M2 macrophage polarization through targeting IL-33 via miR-19b - Nature.com
Article by Li Pi, Bairong Fang, Xianxi Meng and Li Qian (Changsha, China - Cell Death Discovery).
The authors' findings indicate that XIST can promote burn wound healing and enhance the polarization of M2 macrophages by targeting the IL-33/miR-19b axis, which may serve as a potential theoretical basis for the treatment of burn wound healing.
Preparation and Characterization of Polysaccharide-Based Hydrogels for Cutaneous Wound Healing - Mdpi.com
Article by Hongyan Xue, Meng Sun, Xiaoliang Zhao, Yonggang Wang, Jinxin Yan and Weijie Zhang (Lanzhou, China - Polymers).
The plant polysaccharides and CS-based hydrogel should be a candidate for cutaneous wound dressings.
Risk factors for hospital-acquired and community-acquired pressure injuries: a multicentre mixed case-control study - PubMed
Abstract by Lei Ding, Xia Hu, Lili Wei, Mojian Sun, Guixia Sun, Guangfeng Jiang and Huanting Li (Qingdao, China - BMJ Open).
In vivo wound healing effect of Italian and Algerian Pistacia vera L. resins - PubMed
Abstract by Amel Boudjelal, Edoardo Napoli, Abderrahim Benkhaled, Louiza Benazi, Rahima Bey, Davide Gentile and Giuseppe Ruberto (Algeria, Italy - Fitoterapia).
Wound Healing Modulation through the Local Application of Powder Collagen-Derived Treatments in an Excisional Cutaneous Murine Model - Mdpi.com
Article by Selma Benito-Martínez, Bárbara Pérez-Köhler, Marta Rodríguez, Jesús María Izco, José Ignacio Recalde and Gemma Pascual (Spain - Biomedicines).
The authors' findings suggest that the new collagen treatment, compared to the untreated control group, produces significantly faster wound closure and, at the same time, promotes a slight progression of the reparative process compared with the rest of the groups.
Hydrogel assisted synthesis of gold nanoparticles with enhanced microbicidal and in vivo wound healing potential - Nature.com
Article by Zahra Batool, Gulzar Muhammad, Muhammad Mudassir Iqbal, Muhammad Shahbaz Aslam, Muhammad Arshad Raza, Noreen Sajjad, Muhammad Abdullah, Naeem Akhtar, Asad Syed, Abdallah M. Elgorban, Salim S. Al-Rejaie and Zahid Shafiq (Pakistan, USA, Saudi Arabia - Scientific Reports).
The present study reports a hydrogel-based sunlight-assisted synthesis of gold nanoparticles with enhanced antimicrobial and wound healing potential.
Electrical stimulation promotes the wound-healing properties of diabetic human skin fibroblasts - Wiley.com
Abstract by Atieh Abedin-Do, Ze Zhang, Yvan Douville, Mireille Méthot, Julien Bernatchez and Mahmoud Rouabhia (J of Tissue Engineering and Regenerative Medicine).
Flexible printable electrical patches for accelerated wound healing - Newswise.com
A more recent therapy that is being explored is electrical field (EF) stimulation; this method accelerates wound healing with limited side effects. Administering EF stimulation at the wound site activates the migration of skin and other granulation cells to the site, induces blood vessel formation and controls excessive inflammation.
A Retrospective Health Economic Analysis of a Stable Hypochlorous Acid Preserved Wound Cleanser Versus 0.9% Saline Solution as Instillation for Negative-Pressure Wound Therapy in Severe and Infected Wounds - Cureus.com
Article by Kathy E. Gallagher, Emily C. Alberto, Peter J. Mallow, Michel H. Hermans and Luis Cardenas.
The use of NPWT with HAPWOC versus NaCl as instillation in NPWT reduces the number of visits to the operating room and LOS. This has a significant impact on lowering the cost of care when HAPWOC is used.
Why Caregivers Need Education and Support - Woundsource.com
Article by Cheryl Carver.
Providing caregivers with the necessary training, knowledge, and support makes all the difference in patient outcomes. It is critical for caregivers to feel confident, informed, supported, and equipped in their position. We all want the appropriate training for our job roles, and so do caregivers.
Ensuring Equity of Wound Care Through Technology - Woundsource.com
By equipping nurses with the tools necessary to document wounds quickly and accurately, care can be prioritized more effectively. This continuity is especially important during times of the pandemic where we have experienced increases in nursing shortages and traveling nurses moving among hospitals.
Patient Engagement: Encouraging Healing by Involving Patients in Wound Care - Woundsource.com
Patient engagement in wound care improves patient experience and satisfaction and results in increased clinical and economic benefits. As such, it is a worthwhile approach to take, but there are some considerations.
Electrospun Medical Sutures for Wound Healing: A Review - Mdpi.com
Article by Lin Xu, Yanan Liu, Wenhui Zhou and Deng Guang Yu (Shanghai, China - Polymers).
This review firstly discusses the structural classification of sutures and the performance analysis affecting the manufacture and use of sutures, followed by the discussion and classification of electrospinning technology, and then summarizes the relevant research on absorbable and non-absorbable sutures.
Synergistic efficacy of colistin and silver nanoparticles impregnated human amniotic membrane in a burn wound infected rat model - Nature.com
Article by Nadia Wali, Aroosh Shabbir, Nadia Wajid, Nasir Abbas and Syed Zeeshan Haider Naqvi (Pakistan - Scientific Reports).
The authors' study concluded that the increased antimicrobial activity of the novel combination of colistin and silver nanoparticle-loaded decellularized human amniotic membrane manifested its potential as an effective burn wound dressing.
A multicenter clinical trial evaluating the durability of diabetic foot ulcer healing in ulcers treated with topical oxygen and standard of care versus standard of care alone 1 year post healing - Wiley.com
Article by Omar Al-Jalodi, Megan Kupcella, Kristy Breisinger and Thomas E. Serena (International Wound Journal).
At the conclusion of a recently completed randomised controlled DFU clinical trial evaluating the efficacy of topical oxygen therapy and standard of care (SOC) compared to SOC alone, patients with healed ulcers were asked to enrol in a long-term follow-up study.
Solid bone marrow aspirates may be a promising therapeutic approach for promoting wound healing - News-medical.net
A new study compares the regenerative potential of blood/bone marrow aspirate concentrates obtained from arterial blood, venous blood, and bone marrow aspirate. The study, conducted in rabbits, is reported in the peer-reviewed journal Tissue Engineering Part A.
Preparation and Characterization of Platelet Lysate (PL)-Loaded Electrospun Nanofibers for Epidermal Wound Healing - Jpharmsci.org
Article by Simin Nazarnezhad, Farzad Kermani, Vahid Reza Askari, Seyede Atefe Hosseini, Alireza Ebrahimzadeh-Bideskan, Ali Moradi, Reza Kazemi Oskuee, Sahar Mollazadeh and Saeid Kargozar (Journal of Pharmaceutical Sciences).
The tailored fabrication of PCL/GEL-PVA/CS nanofibers may be considered a suitable construct for epidermal wound healing.
Fluorescent Imaging as a Component of Diagnosing Pyoderma Gangrenosum: A Case Report - PubMed
Abstract by Brett G MacLeod, Carissa S Klarich, Laurel L Wessman, Kevin J Gaddis, Nikifor K Konstantinov, Angie Wubben and M Mark Melin (Minneapolis, USA - Adv Skin Wound Care).
Repositioning Strategies to Prevent Pressure Injuries in the ICU: Integrative Review on Implementation Factors - PubMed
Abstract by Symone Everett Day, Binu Koirala and Kimberly McIltrot (Baltimore, USA - Adv Skin Wound Care).
A tannin-functionalized soy protein-based adhesive hydrogel as a wound dressing - Sciencedirect.com
Article by Xinxin Huang, Chao Ma, Yecheng Xu, Jinfeng Cao, Jingchao Li, Jianzhang Li, Sheldon Q. Shi and Qiang Gao (China, USA - Industrial Crops and Products).
This study provides a convenient approach to preparing multifunctional hydrogels and promoting the application of soy protein isolate in biomedical materials.
The potential application of Spirulina in dermatology - Wiley.com
Abstract by Isadora Kaniak Ikeda, Eduardo Bittencourt Sydney, Alessandra Cristine and Novak Sydney (JCD).
Immortelle essential oil-based ointment improves wound healing in a diabetic rat model - PubMed
Abstract by Marijana Andjić, Nevena Draginić, Aleksandar Kočović, Jovana Jeremić, Ksenija Vučićević, Nevena Jeremić, Veljko Krstonošić, Biljana Božin, Nebojša Kladar, Ivan Čapo, Ljiljana Andrijević, Danijela Pecarski, Sergey Bolevich, Vladimir Jakovljević and Jovana Bradić (Serbia, Russia - Biomed Pharmacother.).
Ropivacaine inhibits wound healing by suppressing the proliferation and migration of keratinocytes via the PI3K/AKT/mTOR Pathway - Biomedcentral.com
Article by Xiaoyang Wu, Quanyu Sun, Simeng He, Ya Wu, Shihan Du, Lirong Gong, Jianbo Yu and Haifeng Guo (China - BMC Anesthesiology).
The authors' research demonstrated that ropivacaine treatment showed a more decreased wound closure rate. Mechanistically, they found that ropivacaine suppressed the proliferation and migration of keratinocytes and altered the expression of cytokines by inhibiting PI3K/AKT/mTOR pathway.
A Prospective Randomized Controlled Multicenter Clinical Trial Comparing Paste-Type Acellular Dermal Matrix to Standard Care for the Treatment of Chronic Wounds - Mdpi.com
Article by Youn Hwan Kim, Hyung Sup Shim, Jihye Lee and Sang Wha Kim (Seoul, Korea - JCM).
Paste-type acellular dermal matrix might be a useful option for wound healing and can be applied safely and efficiently for advanced wound care.
Preparing and Characterizing Novel Biodegradable Starch/PVA-Based Films with Nano-Sized Zinc-Oxide Particles for Wound-Dressing Applications - Mdpi.com
Article by Mohammad Mohsen Delavari and Ion Stiharu (Montreal, Canada - Applied Sciences).
The new starch-based materials exhibited suitable physical and chemical properties, including solubility, gel fraction, fluid absorption, biodegradability, surface morphology (scanning electron microscopy imaging), and mechanical properties.
Down-Regulation of miR-138 Alleviates Inflammatory Response and Promotes Wound Healing in Diabetic Foot Ulcer Rats via Activating PI3K/AKT Pathway and hTERT - Dovepress.com
Article by Jian Wang, Xiaodan Zhao, Guichang Tian, Xiaochao Liu, Chengyan Gui and Lin Xu (Yantai, China - Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy).
Down-regulation of miR-138 could alleviate inflammatory response and promote wound healing in DFU rats by activating PI3K/AKT pathway and hTERT.
Goat intestinal tissues yield wound healing biomaterial - Nature.com
Researchers have devised effective techniques to extract biomaterial from goat intestinal tissues. It was able to regenerate cells and inhibit the growth of specific pathogenic bacteria.
Wound care in hidradenitis suppurativa - Wiley.com
Abstract by Omkar Mayur and Priyanka Vedak (Dermatological Reviews).
Association of Wound Healing With Quality and Continuity of Care and Sociodemographic Characteristics - Ajmc.com
Article by Sang Kyu Cho, Soeren Mattke, Mary Sheridan and William Ennis (USA - The American Journal of Managed Care).
Clinic-level measures of care continuity, clinical quality, and sociodemographic composition of their catchment areas’ population explain a meaningful part of differences in clinics’ wound healing performance. Better care continuity appears to have a greater beneficial effect in disadvantaged populations.
Sub-epidermal moisture assessment as a prompt for clinical action in treatment of pressure ulcers in at-risk hospital patients - PubMed
Abstract by Karen Ousey, John Stephenson and Joanna Blackburn (Huddersfield, UK - J Wound Care).
Use of injectable acellular dermal matrix combined with negative pressure wound therapy in open diabetic foot amputation - PubMed
Abstract by Jiyong Ahn, Ho Youn Park, Asode Ananthram Shetty and Wonha Hwang (South Korea, UK - J Wound Care).
Modified application of vacuum-assisted closure in thoracic surgery patients - PubMed
Abstract by Farouk Alreshaid and Yasser Aljehani (Al Khobar, Saudi Arabia - J Wound Care).
Wound Management: The Challenges of a Global Pandemic - Woundsource.com
Article by Martin Vera.
No one estimated the timeline on this pandemic. We just hit the two-year mark, and it’s not completely over. Positively speaking, most of us want to act like all is well and just get on with our lives. Unfortunately, others didn’t believe it’s over, and a massive amount of people still don’t, whereas others just thought that as long as it didn’t hit home, they were OK.
Legal Perils and Pitfalls of Wound Care – Tube Feed or Not Tube Feed. That Is the Question! - Woundsource.com
Article by Heidi Cross.
Many individuals experience unintentional weight loss at older ages, a condition often called the “anorexia of aging.” This is defined as a decrease in appetite and/or food intake in old age. It often is the result of physiologic and hormonal changes.
Effect of a wound healing protocol on patients with stage III and IV pressure ulcers: a preliminary observational study - Magonlinelibrary.com
Abstract by Dario Monaco, Francesco Zaghini, Jacopo Fiorini, Giulia Venturini, Paolo Iovino, Ercole Vellone, Rosaria Alvaro and Alessandro Sili (J. of Wound Care).
Mupirocin Promotes Wound Healing by Stimulating Growth Factor Production and Proliferation of Human Keratinocytes - Frontiersin.org
Article by Danielle Twilley, Oleg Reva, Debra Meyer and Namrita Lall (South Africa, USA, India, Jamaica - Front. Pharmacol.).
This is the first report on the effect of mupirocin on growth factors expressed by human keratinocytes as well as the stimulation of keratinocyte proliferation.
Topical application of oxygen nano-bubble water enhances the healing process of ischaemic skin wound healing in an animal model - Wiley.com
Article by Kohei Aoki, Yukiko Ida, Noritoshi Fukushima and Hajime Matsumura (Shinjuku, Japan - Int. Wound J.)
The authors found that O2NBW used in TOT can promote ischaemic wound healing by stimulating collagen deposition and angiogenesis.
Epidermal Expression of Collagenase Delays Wound-Healing in Transgenic Mice - Rutgers.edu
Abstract by Teresa Di Colandrea, Kiran K Chada, Lisy Wang, John Wille and Jeanine D’Armiento (USA - J. of Investigative Dermatology).
Status and challenges of electrical stimulation use in chronic wound healing - Sciencedirect.com
Abstract by Miruna Verdes, Kimberly Mace, Lee Margetts and Sarah Cartmell (Manchaster, UK - Current Opinion in Biotechnology).
Volatile Organic Compounds in the Early Diagnosis of Non-healing Surgical Wounds: A Systematic Review - Springer.com
Abstract by Nicola Reeves, Samuel Phillips, Aron Hughes, Sarah Maddocks, Matthew Bates, Jared Torkington, Lori Robins and Julie Cornish (World Journal of Surgery)
Effect of Chinese herbal topical medicine, acupuncture, and moxibustion on pressure ulcer wound healing: A meta-analysis - Wiley.com
Article by Feida Wang, Mingxu Chen and Jia Du (Int. Wound J.).
Traditional Chinese medicine treatments had a significantly higher complete healing and curative ratio post-treatment compared with control for subjects with pressure ulcer wounds.
Finding the Right Covering for a Wound - Generalsurgerynews.com
Article by Victoria Stern.
The ultimate goal of wound care is to accelerate healing and prevent acute wounds from becoming chronic. Part of this process involves choosing a wound dressing that complements the characteristics of the wound.
Molecular mechanisms of skin wound healing in non-diabetic and diabetic mice in excision and pressure experimental wounds - Researchgate.net
Article by Vito Antonio Baldassarro, Luca Lorenzini, Alessandro Giuliani, Maura Cescatti, Giuseppe Alastra, Micaela Pannella, Bruno Pietro Imbimbo, Gino Villetti, Laura Calzà and Luciana Giardino (Italy - Cell Tissue Res.).
The molecular analysis suggests that db/db mice have a longer inflammatory phase of the wound repair process, delaying the progression toward the proliferation and remodeling phases.
Risk Factors for Hospital-Acquired Pressure Injury in Adult Critical Care Patients - Researchgate.net
Abstract by Phillip Kim, Vamsi K Aribindi, Amy M Shui, Sharvari S Deshpande, Sachin Rangarajan, Kaelan Schorger, J Matthew Aldrich and Hanmin Lee (San Francisco, USA - Am J Crit Care).
Elastic Fibre Proteins in Elastogenesis and Wound Healing - Mdpi.com
Article by Xinyang Zhang, Yasmene F. Alanazi, Thomas A. Jowitt, Alan M. Roseman and Clair Baldock (UK, Saudi Arabia - IJMS).
The authors summarise the elastic fibres' roles in elastogenesis, discuss the effect of their mutations on relevant diseases, and describe their interactions involved in forming the elastic fibre network.
Assessing the inflammatory response to in vitro polymicrobial wound biofilms in a skin epidermis model - Nature.com
Article by Jason L. Brown, Eleanor Townsend, Robert D. Short, Craig Williams, Chris Woodall, Christopher J. Nile and Gordon Ramage (UK - npj Biofilms and Microbiomes).
The authors' primary aim was to create a complex in vitro biofilm model containing a range of microorganisms commonly isolated from the infected wound milieu.
Food and Drug Administration perspective: Advancing product development for non-healing chronic wounds - Wiley.com
Abstract by Kapil Dev Verma, Felisa Lewis, Maryjoy Mejia, Meghana Chalasani and Kendall A. Marcus (Wound Repair and Regeneration).
Incisional Negative Pressure Wound Therapy to Decrease the Incidence of Surgical Site Infections in Trauma Laparotomy Wounds - PubMed
Abstract by Ishraq Kabir, Tuan Nguyen, Julia Heaton, Kristen Peterson and Michael Martyak (Norfolk, USA - Am Surg.).
The Impact of Prolonged Inflammation on Wound Healing - Mdpi.com
Article by Judith C. J. Holzer-Geissler, Simon Schwingenschuh, Martin Zacharias, Johanna Einsiedler, Sonja Kainz, Peter Reisenegger, Christian Holecek, Elisabeth Hofmann, Barbara Wolff-Winiski, Hermann Fahrngruber, Thomas Birngruber, Lars-Peter Kamolz and Petra Kotzbeck (Austria - Biomedicines).
By using resiquimod, the authors were able to show that prolonged inflammation delayed wound healing, which is often observed in chronic wounds in patients. The model they used shows the importance of inflammation in wound healing and gives an insight into the progression of chronic wounds.
Revolutionizing non-conventional wound healing using honey by simultaneously targeting multiple molecular mechanisms - Sciencedirect.com
Article by Carlos C. F. Pleeging, Frank A. D. T. G. Wagener, Hilde de Rooster and Niels A. J. Cremers (The Netherlands, Belgium - Drug Resistance Updates).
Honey is a valuable alternative to conventional antimicrobial and anti-inflammatory therapies that can strongly reduce nosocomial infections.
A Relevant Wound-Like in vitro Media to Study Bacterial Cooperation and Biofilm in Chronic Wounds - Frontiersin.org
Article by Cassandra Pouget, Catherine Dunyach-Remy, Thierry Bernardi, Christian Provot, Jason Tasse, Albert Sotto and Jean-Philippe Lavigne (France - Front. Microbiol.).
The authors' data confirmed the impact of the chronic wound environment on biofilm formation and bacteria virulence. They indicated that P. aeruginosa and S. aureus cooperated in coinfected wounds.
Biofilm Survival Strategies in Chronic Wounds - Mdpi.com
Article by Ida Clement Thaarup, Anne Kristine Servais Iversen, Mads Lichtenberg, Thomas Bjarnsholt and Tim Holm Jakobsen (Copenhagen, Denmark - Microorganism).
The authors have strived to clarify the limitations of the current knowledge in regard to this specific topic, without ignoring important in vitro and in vivo observations.
Wound fluid sampling methods for proteomic studies: A scoping review - Wiley.com
Article by Joe Harvey, Kieran T. Mellody, Nicky Cullum, Rachel E. B. Watson and Jo Dumville (Manchester, UK - Wound Repair and Regeneration).
This scoping review highlights the variety of methods used for wound fluid collection. Many studies had small sample sizes and short sample collection periods; these weaknesses have hampered the discovery and validation of novel biomarkers.
Tips for a Successful Wound Care Telemedicine Consultation - Hmpgloballearningnetwork.com
Article by Alisha Oropallo.
The widespread adoption of this technology has enabled flexible interaction with the patient regardless of time and location, and more importantly to limit unnecessary exposure, particularly for high-risk individuals.
Why Won’t This Heal? Dealing With a Recalcitrant Wound: Part 2 - Woundsource.com
Article by Becky Naughton. In Part 1 of this series on recalcitrant wounds, we started our discussion on some factors on why wounds may seem to stall or stop healing. In Part 2, we will discuss other possible factors that can cause a recalcitrant wound.
Skinfold Assessment, Management, and Moisture - Woundsource.com
Article by Holly Hovan.
The literature suggests that patients with a high degree of adiposity are more at risk for inflammatory conditions, and the numbers of these patients continue to rise.
Non-contact electrical stimulation as an effective means to promote wound healing - PubMed
Abstract by Junwei Xu, Yunxue Jia, Weizhen Huang, Qiusheng Shi, Xuemei Sun, Lisha Zheng, Ming Wang, Ping Li and Yubo Fan (Beijing, China - Bioelectrochemistry).
Wound healing properties of Carica papaya latex: In vivo evaluation in mice burn model - Academia.eu
Article by Shila Gurung and Natasa Skalko-Basnet (Nepal, Norway - Journal of Etnopharmacology, 2008).
It may be concluded that papaya latex formulated in the Carbopol gel is effective in thetreatment of burns and thus supports its traditional use.
Targeting a protein to combat slow wound healing - Medicalxpress.com
Article by Mike Addelman.
Untreatable wounds are likely to get better when the levels of a biochemical catalyst found in the skin increases, find scientists at The University of Manchester.
Wild Blueberry Extract May Help Wounds Heal Faster - Scitechdaily.com
Wild blueberries have the potential to enhance cell migration, new blood vessel formation (angiogenesis) and vascularization and to speed up wound closure. This is especially important in conditions that require enhanced wound closure in patients with chronic wounds such as diabetic wounds, burns and pressure ulcers.
Pyoderma gangrenosum study pilot registry: The first step to a better understanding - PubMed
Abstract by Victoria E Orfaly, Ashley M Reese, Marcia Friedman, Emile Latour and Alex G Ortega-Loayza (Portland, USA - Wound Repair Regen.).
Biopaper Based on Ultralong Hydroxyapatite Nanowires and Cellulose Fibers Promotes Skin Wound Healing by Inducing Angiogenesis - Mdpi.com
Article by Jing Gao, Liang-Shi Hao, Bing-Bing Ning, Yuan-Kang Zhu, Ju-Bo Guan, Hui-Wen Ren, Han-Ping Yu, Ying-Jie Zhu and Jun-Li Duan (China - Coatings).
The biopaper can promote the rat skin to achieve thicker skin re-epithelialization and the formation of new blood vessels, and thus promote the healing of the wound. Therefore, the ultralong HAP nanowire-based biopaper has the potential to be a safe and effective wound dressing and has significant clinical application prospects.
10 Things to Know About Hyperbaric Oxygen Therapy - Generalsurgerynews.com
Article by Chase Doyle. The top 10 things that every provider should know about HBO therapy. They include the differences between topical and systemic HBO therapy, as well as various indications, contraindications and side effects.
Use of collagen and negative pressure wound therapy on a diabetic foot ulcer: a case study - PubMed
Abstract by Marcela Pacheco Cifuentes (Santiago, Chile - J. Wound Care).
Accelerated Skin Wound Healing Using Flexible Photovoltaic-Bioelectrode Electrical Stimulation - Mdpi.com
Article by Chao Han, Junfei Huang, Aodi Zhangji, Xufeng Tong, Kaige Yu, Kai Chen, Xinlan Liu, Yang Yang, Yuxin Chen, Waqar Ali Memon, Kamran Amin, Wanlei Gao, Zexing Deng, Kun Zhou, Yuheng Wang and Xiangdong Qi (China - Micromachines).
The results of in vitro cell experiments and diabetic skin-relieving biological experiments showed the proliferation of skin fibroblasts and the expression of transforming growth factors increased, and the skin wounds of diabetic mouse healed faster.
Neutrophils guide pre-existing matrix into injured organs to initiate tissue repair - Nature.com
Abstract by Lai Guan Ng (Singapore - Nature Immunology).
Biomimetic Peptide Nanoparticles Participate in Natural Coagulation for Hemostasis and Wound Healing - Rsc.org
Abstract by Huange Xu, Qilin Liang, Litao Li, Gaofeng Qi, Lei Wang, Lining Zhan, Mengru Ding, Kuo Zhang and Xu Cui (Biomaterials Science).
Hydrogel films of methanolic Mentha piperita extract and silver nanoparticles enhance wound healing in rats with diabetes Type I - Tandfonline.com
Article by Mariam Mojallya, Eram Sharmin, Yosra Alhindi, Najla A. Obaid, Riyad Almaimani, Mohamed Althubiti, Shakir Idris, Abdelghany H. Abdelghany, Bassem Refaat, Hiba S. Al-Amodi, Ashraf N. Abdalla and Hala F. M. Kamel (Saudi Arabia - Journal of Taibah University for Science).
Hydrogel film with mint and loaded silver nanoparticles (Gel 2) significantly improved wound-healing time in diabetic rats.
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